indigo carmine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4575 | 860-22-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Indolesulfonic acid used as a dye in renal function testing for the detection of nitrates and chlorates, and in the testing of milk. It is a dye excreted by the kidney through tubular secretion and enhances visualization of the ureteral orifices by its deep blue color.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| July 8, 2022 | FDA | PROVEPHARM SAS |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V04CH02 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Tests for renal function and ureteral injuries |
| MeSH PA | D004396 | Coloring Agents |
| CHEBI has role | CHEBI:50412 | two-colour indicator |
| CHEBI has role | CHEBI:77178 | biological stain |
| CHEBI has role | CHEBI:77182 | food coloring |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Visualization of the ureteral orifices | indication | 236168003 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
|---|---|---|---|---|---|---|---|---|---|
| 40MG/5ML (8MG/ML) | BLUDIGO | PROVEPHARM SAS | N216264 | July 8, 2022 | RX | SOLUTION | INTRAVENOUS | July 8, 2027 | NEW CHEMICAL ENTITY |
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4022196 | VUID |
| N0000148133 | NUI |
| 4018104 | VANDF |
| 4020216 | VANDF |
| 4022196 | VANDF |
| 4041712 | VANDF |
| CHEBI:31695 | CHEBI |
| CHEMBL2105023 | ChEMBL_ID |
| DB11577 | DRUGBANK_ID |
| 227312 | RXNORM |
| 4874 | MMSL |
| 6084 | MMSL |
| NOCODE | MMSL |
| d03700 | MMSL |
| 001233 | NDDF |
| 002341 | NDDF |
| 010433 | NDDF |
| 412548006 | SNOMEDCT_US |
| 783880009 | SNOMEDCT_US |
| C0021219 | UMLSCUI |
| D007203 | MESH_DESCRIPTOR_UI |
| 2723854 | PUBCHEM_CID |
| D01563 | KEGG_DRUG |
| D3741U8K7L | UNII |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Indigo Carmine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0517-0375 | INJECTION, SOLUTION | 8 mg | INTRAMUSCULAR | UNAPPROVED DRUG OTHER | 13 sections |
| Indigo Carmine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4520 | INJECTION, SOLUTION | 8 mg | INTRAMUSCULAR | UNAPPROVED DRUG OTHER | 13 sections |
| BLUDIGO | HUMAN PRESCRIPTION DRUG LABEL | 1 | 81284-315 | INJECTION | 8 mg | INTRAVENOUS | NDA | 25 sections |
| BLUDIGO | HUMAN PRESCRIPTION DRUG LABEL | 1 | 81284-315 | INJECTION | 8 mg | INTRAVENOUS | NDA | 25 sections |