flumetasone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| prednisone and prednisolone derivatives | 4548 | 2135-17-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An anti-inflammatory glucocorticoid used in veterinary practice.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D07AB03 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, PLAIN Corticosteroids, moderately potent (group II) |
| ATC | D07BB01 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, COMBINATIONS WITH ANTISEPTICS Corticosteroids, moderately potent, combinations with antiseptics |
| ATC | D07CB05 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, COMBINATIONS WITH ANTIBIOTICS Corticosteroids, moderately potent, combinations with antibiotics |
| ATC | D07XB01 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, OTHER COMBINATIONS Corticosteroids, moderately potent, other combinations |
| ATC | S02CA02 | SENSORY ORGANS OTOLOGICALS CORTICOSTEROIDS AND ANTIINFECTIVES IN COMBINATION Corticosteroids and antiinfectives in combination |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D005938 | Glucocorticoids |
| MeSH PA | D006728 | Hormones |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Atopic dermatitis | indication | 24079001 | DOID:3310 |
| Contact dermatitis | indication | 40275004 | DOID:2773 |
| Seborrheic dermatitis | indication | 50563003 | DOID:8741 |
| Lichen simplex chronicus | indication | 53891004 | |
| Granuloma annulare | indication | 65508009 | DOID:3777 |
| Pruritus ani | indication | 90446007 | |
| Discoid lupus erythematosus | indication | 200938002 | |
| Plaque psoriasis | indication | 200965009 | |
| Scalp psoriasis | indication | 238608008 | |
| Pruritus of genital organs | indication | 267802000 | |
| Eruption of skin | indication | 271807003 | DOID:0050486 |
| Primary cutaneous T-cell lymphoma | indication | 400122007 | |
| Hypopituitarism | contraindication | 74728003 | DOID:9406 |
| Skin striae | contraindication | 201066002 | |
| Telangiectasia disorder | contraindication | 247479008 | |
| Atrophoderma | contraindication | 399979006 |
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cats | Acute and chronic dermatoses of varying etiology | Indication |
| Dogs | Musculoskeletal conditions caused by inflammation of muscles or joints and accessory structures where permanent structural changes do not exist | Indication |
| Dogs | Acute and chronic dermatoses of varying etiology | Indication |
| Dogs | Otitis externa in conjunction with topical medication | Indication |
| Dogs | Allergic states | Indication |
| Dogs | Shock and shock-like states | Indication |
| Horse | Musculoskeletal conditions caused by inflammation, where permanent structural changes do not exist | Indication |
| Horse | Allergic states | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Flucort Solution | Zoetis Inc. | 1 |
| Flucort Tablets | Zoetis Inc. | 1 |
| Anaprime Suspension | Zoetis Inc. | 1 |
| Anaprime Ophthalmic Solution | Zoetis Inc. | 3 |
| Anaprime Opthakote Ophthalmic | Zoetis Inc. | 3 |
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 11.06 | acidic |
| pKa2 | 12.45 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D04208 | KEGG_DRUG |
| N0000167461 | NUI |
| CHEBI:34764 | CHEBI |
| CHEMBL1201392 | ChEMBL_ID |
| DB00663 | DRUGBANK_ID |
| 4458 | RXNORM |
| 004949 | NDDF |
| 116598007 | SNOMEDCT_US |
| 3037004 | SNOMEDCT_US |
| C0016294 | UMLSCUI |
| D005443 | MESH_DESCRIPTOR_UI |
| 16490 | PUBCHEM_CID |
| 1355 | INN_ID |
| LR3CD8SX89 | UNII |
Pharmaceutical products:
None