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cupric chloride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4530 | 7447-39-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK1,JAK2,JAK3,MAP2K6,MAP3K14,MAP3K21,MAP3K7,MAP4K1,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MARK4,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKCD,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ZAP70 | 61 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| June 26, 1986 | FDA | HOSPIRA |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Kounis syndrome | 45.47 | 43.87 | 9 | 749 | 2544 | 90625145 |
| Vaginal flatulence | 44.98 | 43.87 | 12 | 746 | 12626 | 90615063 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Vaginal flatulence | 45.42 | 36.02 | 12 | 915 | 12132 | 110576240 |
| Female genital tract fistula | 41.76 | 36.02 | 12 | 915 | 16507 | 110571865 |
| Proctitis | 41.47 | 36.02 | 12 | 915 | 16915 | 110571457 |
| Vaginal discharge | 40.80 | 36.02 | 12 | 915 | 17896 | 110570476 |
| Radiculopathy | 39.89 | 36.02 | 12 | 915 | 19324 | 110569048 |
| Macular degeneration | 38.55 | 36.02 | 12 | 915 | 21647 | 110566725 |
| Kounis syndrome | 37.89 | 36.02 | 9 | 918 | 5916 | 110582456 |
| Chronic sinusitis | 36.82 | 36.02 | 12 | 915 | 25072 | 110563300 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| CHEBI has role | CHEBI:86385 | Delta(7)-cholestenol Delta(7)-Delta(8)-isomerase inhibitors |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Wilson's disease | contraindication | 88518009 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D03612 | KEGG_DRUG |
| 4018533 | VUID |
| N0000146855 | NUI |
| 10125-13-0 | SECONDARY_CAS_RN |
| 4017668 | VANDF |
| 4018533 | VANDF |
| CHEBI:49553 | CHEBI |
| CHEMBL444436 | ChEMBL_ID |
| C029892 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB09131 | DRUGBANK_ID |
| S2QG84156O | UNII |
| 21833 | RXNORM |
| 3685 | MMSL |
| 37993 | MMSL |
| 4512 | MMSL |
| 000854 | NDDF |
| C0056593 | UMLSCUI |
| CUL | PDB_CHEM_ID |
| 24014 | PUBCHEM_CID |
| S2QG84156O | INXIGHT DRUGS |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| COPPER | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-4092 | INJECTION, SOLUTION | 0.40 mg | INTRAVENOUS | NDA | 19 sections |
| CUPRIC CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51754-0103 | INJECTION, SOLUTION | 0.40 mg | INTRAVENOUS | ANDA | 21 sections |
| Cupric Chloride | HUMAN PRESCRIPTION DRUG LABEL | 1 | 70069-506 | INJECTION | 0.40 mg | INTRAVENOUS | ANDA | 13 sections |
| CUPRIC CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72603-351 | INJECTION, SOLUTION | 0.40 mg | INTRAVENOUS | ANDA | 12 sections |
| CUPRIC CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72819-234 | INJECTION, SOLUTION | 0.40 mg | INTRAVENOUS | ANDA | 12 sections |
| CUPRIC CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72819-234 | INJECTION, SOLUTION | 0.40 mg | INTRAVENOUS | ANDA | 12 sections |
| CUPRIC CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 80830-2301 | INJECTION, SOLUTION | 0.40 mg | INTRAVENOUS | ANDA | 12 sections |
| CUPRIC CHLORIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 84897-013 | INJECTION, SOLUTION | 0.40 mg | INTRAVENOUS | ANDA | 12 sections |