ferrous sulfate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4528	7720-78-7

Description:

Molecule	Description
Synonyms: ferrous sulfate ferrous sulfate, dried	Ferro-Gradumet is ferrous sulfate in controlled release form; RN given refers to Fe(+2)[1:1] salt Molecular weight: 151.90 Formula: FeO4S CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 80.26 ALOGS: ROTB: None

Molecule

Description

Synonyms:

ferrous sulfate
ferrous sulfate, dried

Ferro-Gradumet is ferrous sulfate in controlled release form; RN given refers to Fe(+2)[1:1] salt

Molecular weight: 151.90
Formula: FeO4S
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 80.26
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
0.20	g	O

ADMET properties:

Show entries

Search:

Property	Value	Reference
S (Water solubility)	570 mg/mL	Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose)	30.56 µM/kg/day	Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BDDCS (Biopharmaceutical Drug Disposition Classification System)	3	Benet LZ, Broccatelli F, Oprea TI

Showing 1 to 3 of 3 entries

Previous1Next

Approvals:

Date	Agency	Company	Orphan
Aug. 13, 1946	FDA	LEDERLE

FDA Adverse Event Reporting System (Female)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Drug ineffective	220.58	10.23	303	49767	1044462	62394490
Acute kidney injury	166.77	10.23	521	49549	262894	63176058
Anaemia	126.80	10.23	512	49558	292918	63146034
Contraindicated product administered	115.58	10.23	17	50053	217631	63221321
Drug intolerance	114.66	10.23	50	50020	308611	63130341
Hand deformity	111.70	10.23	3	50067	159454	63279498
Glossodynia	104.77	10.23	10	50060	178866	63260086
Systemic lupus erythematosus	100.71	10.23	21	50049	208897	63230055
Arthropathy	88.80	10.23	37	50033	234755	63204197
Hepatic enzyme increased	88.41	10.23	25	50045	202303	63236649

Showing 1 to 10 of 208 entries

Previous1 2 3 4 5…21Next

FDA Adverse Event Reporting System (Male)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Acute kidney injury	79.11	11.87	446	26055	304542	34625888
Drug ineffective	65.77	11.87	157	26344	456594	34473836
Completed suicide	56.01	11.87	5	26496	98163	34832267
Foetal exposure during pregnancy	55.68	11.87	102	26399	37999	34892431
Hyperkalaemia	54.79	11.87	145	26356	69244	34861186
Foetal disorder	46.47	11.87	19	26482	807	34929623
Hospitalisation	46.02	11.87	120	26381	56782	34873648
Anaemia	45.78	11.87	318	26183	233017	34697413
Faeces discoloured	45.05	11.87	56	26445	14822	34915608
Gastrointestinal tract mucosal pigmentation	44.58	11.87	16	26485	474	34929956

Showing 1 to 10 of 73 entries

Previous1 2 3 4 5…8Next

FDA Adverse Event Reporting System (Geriatric)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Acute kidney injury	231.61	10.32	930	63517	518474	79161467
Drug ineffective	194.72	10.32	362	64085	1080551	78599390
Anaemia	145.37	10.32	727	63720	444288	79235653
Completed suicide	132.96	10.32	20	64427	245747	79434194
Hypervolaemia	100.67	10.32	147	64300	42543	79637398
Hyperkalaemia	100.47	10.32	259	64188	114139	79565802
Drug intolerance	92.56	10.32	49	64398	264070	79415871
Haemoglobin decreased	92.46	10.32	390	64057	221729	79458212
Gastrointestinal haemorrhage	86.11	10.32	289	64158	147430	79532511
Contraindicated product administered	74.20	10.32	18	64429	157520	79522421

Showing 1 to 10 of 227 entries

Previous1 2 3 4 5…23Next

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Show entries

Search:

Source	Code	Description
ATC	B03AA07	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron bivalent, oral preparations
ATC	B03AD03	BLOOD AND BLOOD FORMING ORGANS ANTIANEMIC PREPARATIONS IRON PREPARATIONS Iron in combination with folic acid
CHEBI has role	CHEBI:63247	reducer

Showing 1 to 3 of 3 entries

Previous1Next

Drug Use | Suggest Off label Use Form| |View source of the data|

Show entries

Search:

Disease	Relation	SNOMED_ID	DOID
Anemia of prematurity	indication	47100003	DOID:11243
Megaloblastic anemia due to folate deficiency	indication	85649008	DOID:14026
Vitamin deficiency	indication	85670002
Iron deficiency anemia	indication	87522002
Mineral deficiency	indication	111379007
Mineral Deficiency Prevention	indication
Vitamin Deficiency Prevention	indication
Peptic ulcer	contraindication	13200003	DOID:750
Operation on stomach	contraindication	16453004
Primary hyperoxaluria	contraindication	17901006	DOID:2977

Showing 1 to 10 of 20 entries

Previous1 2Next

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

Show entries

Search:

ID	Source
000840	NDDF
007813	NDDF
24393	PUBCHEM_CID
24947	RXNORM
387402000	SNOMEDCT_US
39R4TAN1VT	UNII
4017662	VANDF
4017664	VANDF
4017707	VUID
4017707	VANDF

Showing 1 to 10 of 23 entries

Previous1 2 3Next

Pharmaceutical products:

Show entries

Search:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
FERROUS SULFATE	HUMAN OTC DRUG LABEL	1	50436-5890	TABLET	325 mg	ORAL	Unapproved drug other	10 sections
FERROUS SULFATE	HUMAN OTC DRUG LABEL	1	53807-177	ELIXIR	220 mg	ORAL	UNAPPROVED DRUG OTHER	15 sections
FERROUS SULFATE	HUMAN OTC DRUG LABEL	1	53808-0918	TABLET	325 mg	ORAL	UNAPPROVED DRUG OTHER	10 sections
Ferrous Sulfate	HUMAN OTC DRUG LABEL	1	54738-963	TABLET	325 mg	ORAL	unapproved drug other	11 sections
Ferrous Sulfate	HUMAN OTC DRUG LABEL	1	54738-963	TABLET	325 mg	ORAL	unapproved drug other	11 sections
FERROUS SULFATE	HUMAN OTC DRUG LABEL	2	58607-113	TABLET	65 mg	ORAL	unapproved drug other	9 sections
Ferrous Sulfate	HUMAN OTC DRUG LABEL	1	67296-1555	TABLET, FILM COATED	325 mg	ORAL	unapproved drug other	10 sections
Ferrous Sulfate	HUMAN PRESCRIPTION DRUG LABEL	1	69517-133	TABLET	65 mg	ORAL	unapproved drug other	6 sections
Ferrous Sulfate	Human OTC Drug Label	1	76413-308	TABLET, FILM COATED	325 mg	ORAL	UNAPPROVED DRUG OTHER	10 sections
Ferrous Sulfate	Human OTC Drug Label	1	76413-356	TABLET, FILM COATED	325 mg	ORAL	UNAPPROVED DRUG OTHER	11 sections

Showing 1 to 10 of 13 entries

Previous1 2Next