teriparatide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
peptides and glycopeptides	4514	52232-67-4

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: teriparatide recombinant human forsteo teriparatide teriparatide acetate hPTH 1-34 parathar	A polypeptide that consists of the 1-34 amino-acid fragment of human PARATHYROID HORMONE, the biologically active N-terminal region. The acetate form is given by intravenous infusion in the differential diagnosis of HYPOPARATHYROIDISM and PSEUDOHYPOPARATHYROIDISM. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995) Molecular weight: 4117.77 Formula: C181H291N55O51S2 CLOGP: LIPINSKI: None HAC: 106 HDO: 60 TPSA: 1752.65 ALOGS: ROTB: 144

Molecule

Description

Molfile Inchi Smiles

Synonyms:

teriparatide recombinant human
forsteo
teriparatide
teriparatide acetate
hPTH 1-34
parathar

A polypeptide that consists of the 1-34 amino-acid fragment of human PARATHYROID HORMONE, the biologically active N-terminal region. The acetate form is given by intravenous infusion in the differential diagnosis of HYPOPARATHYROIDISM and PSEUDOHYPOPARATHYROIDISM. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)

Molecular weight: 4117.77
Formula: C181H291N55O51S2
CLOGP:
LIPINSKI: None
HAC: 106
HDO: 60
TPSA: 1752.65
ALOGS:
ROTB: 144

Drug dosage:

Dose	Unit	Route
20	mcg	P

ADMET properties:

Property	Value	Reference
Vd (Volume of distribution)	0.17 L/kg	Lombardo F, Berellini G, Obach RS
CL (Clearance)	21.40 mL/min/kg	Lombardo F, Berellini G, Obach RS
t_half (Half-life)	0.14 hours	Lombardo F, Berellini G, Obach RS

Approvals:

Date	Agency	Company
July 23, 2019	PMDA	Eli Lilly Japan
June 10, 2003	EMA
Nov. 26, 2002	FDA	LILLY

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Fall	1261.69	13.20	1834	63585	333098	50206607
Product complaint	1205.75	13.20	480	64939	10986	50528719
Blood calcium increased	945.35	13.20	361	65058	7358	50532347
Hip fracture	740.53	13.20	445	64974	25486	50514219
Bone pain	710.87	13.20	545	64874	46684	50493021
Muscle spasms	529.36	13.20	728	64691	124825	50414880
Therapy cessation	483.31	13.20	341	65078	25670	50514035
Drug ineffective	475.60	13.20	235	65184	819098	49720607
Injection site haemorrhage	468.08	13.20	310	65109	21036	50518669
Hospitalisation	443.13	13.20	491	64928	67446	50472259
Spinal fracture	441.19	13.20	266	65153	15307	50524398
Product storage error	423.66	13.20	238	65181	11986	50527719
Dizziness	423.20	13.20	1188	64231	345181	50194524
Femur fracture	329.44	13.20	318	65101	37146	50502559
Pelvic fracture	319.14	13.20	194	65225	11326	50528379
Hypercalcaemia	311.18	13.20	251	65168	23101	50516604
Pain in extremity	277.52	13.20	878	64541	271987	50267718
Fracture	272.33	13.20	203	65216	16630	50523075
Injection site erythema	271.95	13.20	405	65014	74531	50465174
Wrist fracture	261.91	13.20	171	65248	11316	50528389
Back pain	245.91	13.20	732	64687	219298	50320407
Injection site bruising	239.98	13.20	266	65153	36502	50503203
Toxicity to various agents	219.55	13.20	14	65405	212485	50327220
Bone density decreased	219.19	13.20	151	65268	10924	50528781
Rib fracture	201.47	13.20	180	65239	19041	50520664
Off label use	198.53	13.20	193	65226	474233	50065472
Injection site haematoma	185.90	13.20	109	65310	5951	50533754
Arthralgia	177.71	13.20	1069	64350	437633	50102072
Drug intolerance	177.64	13.20	34	65385	219070	50320635
Upper limb fracture	173.03	13.20	152	65267	15721	50523984
Infusion related reaction	167.00	13.20	14	65405	169543	50370162
Feeling abnormal	164.86	13.20	443	64976	125049	50414656
Spinal operation	164.63	13.20	102	65317	6158	50533547
Injection site pain	164.43	13.20	410	65009	110614	50429091
Completed suicide	151.70	13.20	4	65415	131885	50407820
Treatment failure	148.50	13.20	7	65412	137630	50402075
Neutropenia	143.57	13.20	13	65406	147952	50391753
Asthenia	142.95	13.20	799	64620	318243	50221462
Acute kidney injury	135.01	13.20	63	65356	227995	50311710
Drug hypersensitivity	134.34	13.20	79	65340	250931	50288774
Lumbar vertebral fracture	133.97	13.20	80	65339	4517	50535188
Femoral neck fracture	129.40	13.20	94	65325	7396	50532309
Product dose omission issue	128.60	13.20	524	64895	183314	50356391
Chronic obstructive pulmonary disease	124.48	13.20	237	65182	53198	50486507
Nephrolithiasis	123.58	13.20	186	65233	34507	50505198
Vertebroplasty	121.41	13.20	35	65384	279	50539426
Synovitis	119.84	13.20	11	65408	123854	50415851
Therapeutic product effect decreased	119.35	13.20	17	65402	136033	50403672
Febrile neutropenia	108.56	13.20	4	65415	97663	50442042
Drug interaction	107.94	13.20	62	65357	199559	50340146
Bone disorder	107.65	13.20	127	65292	18625	50521080
Spinal compression fracture	106.62	13.20	105	65314	12551	50527154
Compression fracture	104.82	13.20	75	65344	5762	50533943
Glossodynia	104.80	13.20	13	65406	115556	50424149
Hand deformity	102.22	13.20	7	65412	100192	50439513
Pyrexia	100.99	13.20	213	65206	379990	50159715
Foot fracture	99.03	13.20	126	65293	19965	50519740
Surgery	97.84	13.20	155	65264	30050	50509655
Product use issue	96.93	13.20	36	65383	149439	50390266
Thoracic vertebral fracture	93.72	13.20	61	65358	4012	50535693
Systemic lupus erythematosus	92.65	13.20	33	65386	140589	50399116
Blood alkaline phosphatase increased	91.81	13.20	170	65249	37356	50502349
Therapeutic product effect incomplete	91.61	13.20	7	65412	91508	50448197
Heart rate increased	90.77	13.20	262	65157	76988	50462717
Product use in unapproved indication	89.59	13.20	20	65399	115799	50423906
Gait disturbance	88.27	13.20	406	65013	149599	50390106
Humerus fracture	87.15	13.20	75	65344	7543	50532162
Palpitations	79.64	13.20	286	65133	94220	50445485
Hepatic enzyme increased	79.62	13.20	39	65380	137341	50402364
Thrombocytopenia	79.06	13.20	33	65386	127640	50412065
Osteitis deformans	77.81	13.20	23	65396	202	50539503
Disease progression	77.35	13.20	15	65404	95851	50443854
Myalgia	77.24	13.20	342	65077	123977	50415728
Ankle fracture	73.41	13.20	96	65323	15626	50524079
Therapy interrupted	73.11	13.20	109	65310	20043	50519662
Rheumatoid arthritis	72.79	13.20	93	65326	202457	50337248
Wound	67.69	13.20	26	65393	105768	50433937
Vitamin D decreased	67.59	13.20	68	65351	8338	50531367
Medication error	67.25	13.20	146	65273	35958	50503747
Patella fracture	66.89	13.20	37	65382	1805	50537900
Pericarditis	66.32	13.20	11	65408	78678	50461027
Malignant neoplasm progression	66	13.20	6	65413	68118	50471587
Rash	65.51	13.20	317	65102	437154	50102551
Stomatitis	64.69	13.20	25	65394	101319	50438386
White blood cell count decreased	63.40	13.20	36	65383	116686	50423019
Cerebrovascular accident	63.03	13.20	266	65153	94414	50445291
Tibia fracture	61.49	13.20	49	65370	4426	50535279
Condition aggravated	60.61	13.20	190	65229	296868	50242837
Lower respiratory tract infection	59.91	13.20	24	65395	95177	50444528
Hand fracture	59.43	13.20	48	65371	4420	50535285
Intentional overdose	59.24	13.20	6	65413	62498	50477207
Lower limb fracture	58.91	13.20	82	65337	14164	50525541
Drug abuse	58.71	13.20	5	65414	59841	50479864
Contusion	57.55	13.20	292	65127	111891	50427814
Recalled product	57.40	13.20	30	65389	1305	50538400
Diarrhoea	56.21	13.20	489	64930	587987	49951718
Stress fracture	55.98	13.20	56	65363	6819	50532886
Leukopenia	55.67	13.20	10	65409	67518	50472187
Swelling	53.66	13.20	112	65307	200760	50338945
Nausea	53.52	13.20	1239	64180	704159	49835546
Platelet count decreased	51.99	13.20	33	65386	100693	50439012
Cardiac disorder	49.72	13.20	145	65274	42834	50496871
Blood parathyroid hormone increased	49.71	13.20	36	65383	2818	50536887
Helicobacter infection	49.17	13.20	4	65415	49698	50490007
Myocardial infarction	48.68	13.20	236	65183	88791	50450914
Pancytopenia	48.45	13.20	24	65395	84006	50455699
Duodenal ulcer perforation	47.05	13.20	3	65416	45608	50494097
Intentional product use issue	45.83	13.20	21	65398	76897	50462808
Psoriasis	45.75	13.20	16	65403	68984	50470721
Breast cancer	45.17	13.20	140	65279	42750	50496955
Balance disorder	45.17	13.20	196	65223	70394	50469311
Malaise	45.02	13.20	645	64774	334887	50204818
Head injury	44.57	13.20	97	65322	23923	50515782
Anaphylactic reaction	44.57	13.20	8	65411	54047	50485658
Urine calcium increased	44.14	13.20	11	65408	46	50539659
Pathological fracture	44.04	13.20	52	65367	7630	50532075
Fractured sacrum	44.02	13.20	28	65391	1770	50537935
Nervousness	43.92	13.20	105	65314	27546	50512159
Therapeutic response decreased	43.57	13.20	5	65414	47226	50492479
Musculoskeletal discomfort	43.55	13.20	73	65346	14825	50524880
Calciphylaxis	43.06	13.20	32	65387	2606	50537099
Hypersensitivity	42.87	13.20	139	65280	215022	50324683
Hip surgery	42.85	13.20	32	65387	2626	50537079
Body height decreased	42.53	13.20	55	65364	8853	50530852
Neutrophil count decreased	42.14	13.20	5	65414	46021	50493684
Suicide attempt	41.92	13.20	8	65411	51724	50487981
Peripheral swelling	41.76	13.20	132	65287	205804	50333901
Joint swelling	41.28	13.20	170	65249	245116	50294589
Fear	40.82	13.20	70	65349	14479	50525226
Bone fissure	40.72	13.20	13	65406	151	50539554
Sinusitis	39.97	13.20	102	65317	170456	50369249
Incorrect product administration duration	39.27	13.20	54	65365	9221	50530484
Cervical vertebral fracture	39.11	13.20	28	65391	2152	50537553
Fracture nonunion	38.84	13.20	28	65391	2176	50537529
Arrhythmia	38.53	13.20	112	65307	33020	50506685
Injection site rash	37.95	13.20	72	65347	16105	50523600
Abdominal pain	37.73	13.20	167	65252	236061	50303644
Lung neoplasm malignant	37.67	13.20	70	65349	15414	50524291
Transient ischaemic attack	37.57	13.20	109	65310	32101	50507604
Breast cancer in situ	36.82	13.20	23	65396	1408	50538297
Folliculitis	36.57	13.20	4	65415	39221	50500484
Bradycardia	36.24	13.20	19	65400	64407	50475298
Neuropathy peripheral	36.22	13.20	43	65376	96714	50442991
Dyspnoea	36.17	13.20	495	64924	547113	49992592
Road traffic accident	36.05	13.20	90	65329	24262	50515443
Alanine aminotransferase increased	35.56	13.20	37	65382	88322	50451383
Death	35.43	13.20	604	64815	324775	50214930
Ulna fracture	35.41	13.20	20	65399	1016	50538689
Wheezing	35.34	13.20	18	65401	62029	50477676
Hypokalaemia	35.24	13.20	37	65382	87955	50451750
Hypotension	34.92	13.20	171	65248	235298	50304407
Hip arthroplasty	34.55	13.20	102	65317	30327	50509378
Post procedural complication	33.93	13.20	66	65353	15038	50524667
Osteocalcin increased	33.91	13.20	6	65413	0	50539705
N-telopeptide urine increased	33.91	13.20	6	65413	0	50539705
Calcinosis	33.37	13.20	24	65395	1858	50537847
Fibula fracture	33.13	13.20	29	65390	2983	50536722
Weight decreased	32.75	13.20	433	64986	220812	50318893
Device failure	32.65	13.20	38	65381	5490	50534215
Movement disorder	32.48	13.20	71	65348	17561	50522144
Injury associated with device	32.27	13.20	29	65390	3088	50536617
Abdominal discomfort	32.21	13.20	172	65247	231469	50308236
Blood calcium abnormal	31.91	13.20	19	65400	1067	50538638
Radius fracture	31.55	13.20	29	65390	3180	50536525
Pain	31.16	13.20	973	64446	577930	49961775
Muscular weakness	31.13	13.20	220	65199	94793	50444912
Blister	30.87	13.20	39	65380	85379	50454326
Multiple fractures	30.29	13.20	40	65379	6571	50533134
Loss of consciousness	29.86	13.20	234	65185	104119	50435586
Accident	29.80	13.20	35	65384	5106	50534599
Memory impairment	29.74	13.20	190	65229	79170	50460535
Muscle injury	29.52	13.20	6	65413	37105	50502600
Atypical femur fracture	29.38	13.20	34	65385	4882	50534823
Back disorder	29.09	13.20	47	65372	9258	50530447
Neck pain	28.86	13.20	148	65271	56919	50482786
Hypercalciuria	28.83	13.20	11	65408	223	50539482
Suicidal ideation	28.77	13.20	18	65401	55367	50484338
Multiple sclerosis relapse	28.41	13.20	10	65409	42954	50496751
Haemoglobin decreased	28.33	13.20	78	65341	127138	50412567
Hyperparathyroidism	28.08	13.20	24	65395	2390	50537315
Clavicle fracture	27.81	13.20	26	65393	2913	50536792
Emphysema	27.17	13.20	45	65374	9048	50530657
Osteonecrosis	27.03	13.20	77	65342	22440	50517265
Agitation	26.84	13.20	18	65401	53366	50486339
Spinal deformity	26.24	13.20	16	65403	938	50538767
Accidental underdose	26.06	13.20	14	65405	644	50539061
Breast calcifications	25.85	13.20	17	65402	1138	50538567
Metabolic acidosis	25.74	13.20	9	65410	38816	50500889
C-reactive protein increased	25.46	13.20	29	65390	66445	50473260
Bone marrow failure	25.29	13.20	3	65416	27621	50512084
Dementia Alzheimer's type	25.06	13.20	16	65403	1018	50538687
Headache	24.79	13.20	842	64577	505693	50034012
Calcium ionised increased	24.67	13.20	8	65411	98	50539607
Vomiting	24.44	13.20	434	64985	460324	50079381
Bone scan abnormal	24.32	13.20	11	65408	347	50539358
Facial bones fracture	24.27	13.20	25	65394	3152	50536553
Joint dislocation	24.26	13.20	51	65368	12282	50527423
Oxygen saturation decreased	23.90	13.20	36	65383	73212	50466493
Blood bilirubin increased	23.84	13.20	6	65413	32032	50507673
Discomfort	23.72	13.20	67	65352	108313	50431392
Enchondromatosis	23.53	13.20	7	65412	63	50539642
Hernial eventration	23.49	13.20	5	65414	8	50539697
Sternal fracture	23.49	13.20	20	65399	1982	50537723
Colon cancer	23.32	13.20	41	65378	8650	50531055
Hypoacusis	23.24	13.20	69	65350	20578	50519127
Bone cancer	23.05	13.20	16	65403	1171	50538534
Heart rate irregular	23.04	13.20	66	65353	19294	50520411
Liver function test increased	22.91	13.20	3	65416	25603	50514102
Angioedema	22.89	13.20	10	65409	37666	50502039
Vein disorder	22.74	13.20	28	65391	4291	50535414
Rhabdomyolysis	22.71	13.20	11	65408	39016	50500689
Osteoporotic fracture	22.68	13.20	24	65395	3121	50536584
Cementoplasty	22.61	13.20	4	65415	0	50539705
Ilium fracture	22.55	13.20	8	65411	131	50539574
Addison's disease	22.44	13.20	7	65412	75	50539630
Nerve compression	22.39	13.20	37	65382	7425	50532280
Aspartate aminotransferase increased	22.08	13.20	42	65377	77956	50461749
Encephalopathy	22.03	13.20	8	65411	33703	50506002
Breast cancer female	21.92	13.20	35	65384	6827	50532878
Hallucination, synaesthetic	21.74	13.20	6	65413	40	50539665
Dysstasia	21.45	13.20	61	65358	17758	50521947
Visual acuity reduced	21.44	13.20	66	65353	20073	50519632
Groin pain	21.38	13.20	40	65379	8851	50530854
Sleep disorder due to general medical condition, insomnia type	21.35	13.20	7	65412	31440	50508265
Cardio-respiratory arrest	21.20	13.20	23	65396	53869	50485836
Type 2 diabetes mellitus	21.08	13.20	9	65410	34366	50505339
Alopecia	20.95	13.20	209	65210	244838	50294867
General physical health deterioration	20.77	13.20	104	65315	142330	50397375
Limb discomfort	20.73	13.20	74	65345	24283	50515422
Hernia hiatus repair	20.68	13.20	6	65413	49	50539656
Hyperkalaemia	20.66	13.20	19	65400	48070	50491635
Leukaemia	20.58	13.20	24	65395	3475	50536230
Drug eruption	20.56	13.20	3	65416	23603	50516102
Hypervolaemia	20.53	13.20	4	65415	25495	50514210
Extraskeletal ossification	20.17	13.20	7	65412	107	50539598
Hepatic cancer	20.16	13.20	23	65396	3252	50536453
Drug withdrawal syndrome	20.06	13.20	4	65415	25077	50514628
Plasma cell myeloma	20.05	13.20	87	65332	31235	50508470
Vertigo	19.97	13.20	125	65294	51707	50487998
Prosthesis implantation	19.79	13.20	6	65413	58	50539647
Serotonin syndrome	19.64	13.20	4	65415	24709	50514996
Influenza	19.46	13.20	189	65230	89349	50450356
Complication associated with device	19.46	13.20	52	65367	14603	50525102
Injection site irritation	19.44	13.20	26	65393	4324	50535381
Transaminases increased	19.23	13.20	6	65413	27818	50511887
Hyponatraemia	19.20	13.20	62	65357	96077	50443628
Constipation	19.18	13.20	342	65077	185366	50354339
Gammopathy	19.17	13.20	7	65412	125	50539580
Productive cough	19.10	13.20	24	65395	52670	50487035
Irritable bowel syndrome	19.10	13.20	23	65396	51418	50488287
Arthropathy	18.87	13.20	123	65296	157783	50381922
Pleural effusion	18.84	13.20	49	65370	81405	50458300
Oedema	18.82	13.20	39	65380	70142	50469563
Tetany	18.62	13.20	16	65403	1605	50538100
Cough	18.51	13.20	211	65208	241053	50298652
Neoplasm malignant	18.46	13.20	70	65349	23645	50516060
Parkinson's disease	18.40	13.20	14	65405	1181	50538524
Musculoskeletal chest pain	18.23	13.20	59	65360	18427	50521278
Intestinal obstruction	18.22	13.20	75	65344	26308	50513397
Hepatitis	18.10	13.20	9	65410	31444	50508261
Injection site streaking	18.04	13.20	5	65414	34	50539671
Rash maculo-papular	17.96	13.20	6	65413	26635	50513070
Drug ineffective for unapproved indication	17.87	13.20	3	65416	21278	50518427
Liver injury	17.78	13.20	5	65414	24801	50514904
Sleep disorder due to a general medical condition	17.53	13.20	33	65386	7338	50532367
Cystitis	17.50	13.20	108	65311	44456	50495249
Fracture malunion	17.33	13.20	7	65412	166	50539539
Sedation	17.25	13.20	9	65410	30601	50509104
Rehabilitation therapy	17.24	13.20	14	65405	1299	50538406
Hepatocellular injury	17.22	13.20	6	65413	25941	50513764
Spinal disorder	17.20	13.20	35	65384	8235	50531470
Product distribution issue	17.18	13.20	11	65408	703	50539002
Infection	17.17	13.20	142	65277	172812	50366893
Growing pains	17.08	13.20	4	65415	12	50539693
Posture abnormal	16.98	13.20	17	65402	2072	50537633
Basosquamous carcinoma of skin	16.96	13.20	3	65416	0	50539705
Wrong product stored	16.96	13.20	3	65416	0	50539705
Pulmonary arterial hypertension	16.76	13.20	3	65416	20316	50519389
Joint arthroplasty	16.75	13.20	17	65402	2106	50537599
Blood creatinine increased	16.72	13.20	47	65372	76113	50463592
Joint injury	16.70	13.20	64	65355	21725	50517980
Upper respiratory tract infection	16.53	13.20	38	65381	65860	50473845
Face injury	16.31	13.20	19	65400	2747	50536958
Injection site discolouration	16.31	13.20	31	65388	6943	50532762
Liver function test abnormal	16.27	13.20	20	65399	44319	50495386
Dystrophic calcification	16.19	13.20	6	65413	112	50539593
Cataract operation	16.01	13.20	23	65396	4088	50535617
Gait inability	15.99	13.20	92	65327	36935	50502770
Parathyroid tumour benign	15.98	13.20	10	65409	614	50539091
Spinal stenosis	15.94	13.20	46	65373	13504	50526201
Coma	15.77	13.20	31	65388	56848	50482857
Urinary bladder polyp	15.51	13.20	5	65414	60	50539645
Jaw disorder	15.50	13.20	25	65394	4918	50534787
International normalised ratio increased	15.28	13.20	20	65399	43132	50496573
Extrasystoles	15.22	13.20	24	65395	4631	50535074
Septic shock	15.14	13.20	32	65387	57143	50482562
Scoliosis	15.09	13.20	29	65390	6547	50533158
Spinal fusion surgery	15.05	13.20	22	65397	3973	50535732
Cardiac failure congestive	14.99	13.20	171	65248	84211	50455494
Skeletal injury	14.88	13.20	12	65407	1102	50538603
Traumatic shock	14.88	13.20	3	65416	3	50539702
Acetabulum fracture	14.85	13.20	7	65412	243	50539462
Loss of personal independence in daily activities	14.81	13.20	44	65375	70006	50469699
Cardiac flutter	14.75	13.20	20	65399	3370	50536335
Depressed level of consciousness	14.68	13.20	28	65391	51925	50487780
Neoplasm	14.67	13.20	27	65392	5901	50533804
Psychotic disorder	14.55	13.20	5	65414	21807	50517898
Wrong technique in device usage process	14.53	13.20	17	65402	2469	50537236
Lymphocyte count decreased	14.44	13.20	8	65411	26299	50513406
Knee operation	14.40	13.20	24	65395	4849	50534856
Pain in jaw	14.39	13.20	92	65327	38336	50501369
Multiple organ dysfunction syndrome	14.33	13.20	27	65392	50310	50489395
Pseudarthrosis	14.19	13.20	8	65411	405	50539300
Dyspnoea exertional	14.14	13.20	28	65391	51205	50488500
Cytomegalovirus infection	14.08	13.20	3	65416	17959	50521746
Mass	14.04	13.20	41	65378	12116	50527589
Manufacturing product shipping issue	14.03	13.20	5	65414	83	50539622
Kyphosis	13.93	13.20	16	65403	2279	50537426
Blood lactate dehydrogenase increased	13.92	13.20	4	65415	19558	50520147
Pulmonary embolism	13.85	13.20	76	65343	101628	50438077
Hyperglycaemia	13.81	13.20	16	65403	36389	50503316
Limb crushing injury	13.80	13.20	6	65413	172	50539533
N-telopeptide urine decreased	13.67	13.20	3	65416	6	50539699
Oestrogen receptor assay positive	13.67	13.20	8	65411	435	50539270
Cardiac pacemaker insertion	13.59	13.20	20	65399	3633	50536072
Arterial disorder	13.57	13.20	11	65408	1018	50538687
Intentional product misuse	13.47	13.20	105	65314	46629	50493076
Tremor	13.45	13.20	216	65203	114687	50425018
Bone graft	13.37	13.20	10	65409	822	50538883
Ascites	13.35	13.20	16	65403	35845	50503860
Angina pectoris	13.29	13.20	68	65351	26120	50513585

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Hip fracture	124.07	21.92	54	5820	10438	29558215
Hospitalisation	118.74	21.92	87	5787	45901	29522752
Product complaint	113.22	21.92	42	5832	5363	29563290
Bone pain	89.79	21.92	52	5822	18400	29550253
Fall	88.06	21.92	139	5735	177039	29391614
Spinal fracture	75.40	21.92	33	5841	6453	29562200
Therapy cessation	68.34	21.92	40	5834	14422	29554231
Spinal operation	62.69	21.92	22	5852	2392	29566261
Bone density decreased	54.14	21.92	18	5856	1662	29566991
Muscle spasms	45.22	21.92	60	5814	65022	29503631
Back pain	43.53	21.92	75	5799	102209	29466444
Arthralgia	42.84	21.92	89	5785	139528	29429125
Vertebroplasty	41.83	21.92	7	5867	26	29568627
Femur fracture	40.21	21.92	22	5852	6969	29561684
Death	39.77	21.92	153	5721	341931	29226722
Pain in extremity	38.15	21.92	74	5800	110359	29458294
Thoracic vertebral fracture	37.29	21.92	13	5861	1385	29567268
Blood calcium increased	36.18	21.92	16	5858	3203	29565450
Injection site pain	35.96	21.92	38	5836	32408	29536245
Injection site erythema	32.80	21.92	25	5849	13931	29554722
Dizziness	31.76	21.92	96	5778	189588	29379065
Acute kidney injury	31.74	21.92	7	5867	265260	29303393
Injection site haemorrhage	31.41	21.92	20	5854	8366	29560287
Fracture	29.26	21.92	17	5857	6036	29562617
Pneumonia	28.40	21.92	132	5742	320040	29248613
Pain	27.96	21.92	86	5788	171346	29397307
Chronic obstructive pulmonary disease	27.25	21.92	37	5837	40918	29527735
Atypical femur fracture	26.64	21.92	7	5867	284	29568369
Injection site bruising	25.74	21.92	17	5857	7563	29561090
Osteoporotic fracture	25.61	21.92	9	5865	982	29567671
Incorrect product administration duration	24.02	21.92	13	5861	4028	29564625
Upper limb fracture	23.99	21.92	13	5861	4038	29564615
Product storage error	23.16	21.92	15	5859	6455	29562198

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Product complaint	1530.79	14.19	486	41769	11468	64445009
Fall	743.81	14.19	1121	41134	415705	64040772
Blood calcium increased	608.63	14.19	224	42031	8318	64448159
Bone pain	492.82	14.19	335	41920	47237	64409240
Product storage error	419.96	14.19	195	42060	13123	64443354
Injection site haemorrhage	411.62	14.19	234	42021	24044	64432433
Hip fracture	403.32	14.19	240	42015	26859	64429618
Muscle spasms	390.29	14.19	471	41784	140552	64315925
Spinal fracture	389.78	14.19	193	42062	14981	64441496
Therapy cessation	310.92	14.19	218	42037	32271	64424206
Dizziness	293.73	14.19	775	41480	429388	64027089
Injection site erythema	290.48	14.19	291	41964	70509	64385968
Injection site bruising	249.68	14.19	200	42055	36173	64420304
Hypercalcaemia	229.05	14.19	179	42076	31237	64425240
Femur fracture	226.46	14.19	184	42071	33951	64422526
Pain in extremity	221.80	14.19	561	41694	302524	64153953
Back pain	219.57	14.19	497	41758	249674	64206803
Wrist fracture	201.33	14.19	108	42147	9893	64446584
Drug ineffective	197.10	14.19	158	42097	840089	63616388
Toxicity to various agents	193.94	14.19	11	42244	363502	64092975
Pelvic fracture	184.87	14.19	104	42151	10459	64446018
Arthralgia	180.59	14.19	667	41588	441593	64014884
Injection site pain	178.12	14.19	286	41969	111122	64345355
Bone density decreased	174.21	14.19	98	42157	9854	64446623
Hospitalisation	172.49	14.19	229	42026	74978	64381499
Acute kidney injury	167.44	14.19	44	42211	449196	64007281
Feeling abnormal	166.36	14.19	307	41948	133295	64323182
Spinal operation	157.43	14.19	78	42177	6055	64450422
Upper limb fracture	140.41	14.19	99	42156	14767	64441710
Fracture	132.66	14.19	105	42150	18650	64437827
Neutropenia	131.67	14.19	6	42249	239618	64216859
Completed suicide	128.85	14.19	4	42251	224410	64232067
Vertebroplasty	125.78	14.19	30	42225	226	64456251
Rib fracture	125.55	14.19	113	42142	23925	64432552
Femoral neck fracture	121.28	14.19	74	42181	8650	64447827
Product dose omission issue	117.46	14.19	336	41919	194411	64262066
Therapy interrupted	110.22	14.19	97	42158	19939	64436538
Lumbar vertebral fracture	104.01	14.19	57	42198	5445	64451032
Off label use	99.23	14.19	164	42091	632642	63823835
Drug interaction	95.11	14.19	60	42195	362023	64094454
Thoracic vertebral fracture	93.97	14.19	50	42205	4503	64451974
Spinal compression fracture	84.22	14.19	73	42182	14702	64441775
Foot fracture	82.52	14.19	79	42176	18078	64438399
Asthenia	80.98	14.19	518	41737	427526	64028951
Nephrolithiasis	80.73	14.19	120	42135	43563	64412914
Pyrexia	77.48	14.19	156	42099	558488	63897989
Pain	73.27	14.19	615	41640	552896	63903581
Product use in unapproved indication	72.26	14.19	14	42241	176604	64279873
Thrombocytopenia	69.18	14.19	30	42225	223771	64232706
Palpitations	67.54	14.19	185	42070	104303	64352174
Humerus fracture	66.43	14.19	49	42206	7836	64448641
Nausea	65.78	14.19	794	41461	785006	63671471
Infusion related reaction	65.28	14.19	14	42241	164453	64292024
Drug abuse	64.77	14.19	6	42249	132368	64324109
Drug intolerance	63.39	14.19	22	42233	187970	64268507
Blood alkaline phosphatase increased	60.94	14.19	122	42133	56157	64400320
Contusion	60.43	14.19	188	42067	113777	64342700
Heart rate increased	60.12	14.19	171	42084	98504	64357973
Disease progression	58.44	14.19	11	42244	141669	64314808
Atypical femur fracture	58.10	14.19	37	42218	4661	64451816
Treatment failure	57.95	14.19	5	42250	116811	64339666
Osteitis deformans	57.08	14.19	15	42240	174	64456303
Hand fracture	56.85	14.19	37	42218	4837	64451640
Compression fracture	55.92	14.19	39	42216	5713	64450764
Chronic obstructive pulmonary disease	53.27	14.19	133	42122	70915	64385562
Malignant neoplasm progression	52.93	14.19	6	42249	112865	64343612
Body height decreased	52.78	14.19	42	42213	7512	64448965
Gait disturbance	52.71	14.19	238	42017	171917	64284560
Pathological fracture	52.35	14.19	45	42210	8960	64447517
Calciphylaxis	50.98	14.19	30	42225	3282	64453195
Therapeutic product effect incomplete	49.81	14.19	5	42250	103477	64353000
Bone disorder	49.54	14.19	58	42197	16701	64439776
Surgery	48.57	14.19	75	42180	28138	64428339
Synovitis	47.14	14.19	5	42250	99085	64357392
Lower limb fracture	47.08	14.19	51	42204	13494	64442983
Urine calcium increased	45.87	14.19	11	42244	85	64456392
Tibia fracture	45.73	14.19	32	42223	4713	64451764
Hypotension	45.69	14.19	115	42140	380859	64075618
Headache	45.44	14.19	538	41717	528929	63927548
Patella fracture	43.28	14.19	21	42234	1557	64454920
Stress fracture	43.04	14.19	33	42222	5591	64450886
Diarrhoea	42.71	14.19	288	41967	722416	63734061
Nervousness	41.95	14.19	72	42183	29484	64426993
Breast cancer	41.37	14.19	71	42184	29077	64427400
Neck pain	40.79	14.19	110	42145	61423	64395054
Pancytopenia	40.02	14.19	22	42233	143287	64313190
Therapeutic product effect decreased	39.74	14.19	13	42242	115338	64341139
Leukopenia	39.39	14.19	9	42246	101233	64355244
Intentional overdose	39.25	14.19	6	42249	89938	64366539
Myalgia	39.01	14.19	206	42049	158411	64298066
Platelet count decreased	38.47	14.19	32	42223	167679	64288798
Musculoskeletal discomfort	37.94	14.19	50	42205	16227	64440250
Bradycardia	37.87	14.19	15	42240	118204	64338273
Injection site rash	37.69	14.19	49	42206	15693	64440784
Blood parathyroid hormone increased	37.07	14.19	24	42231	3110	64453367
Stomatitis	36.63	14.19	13	42242	109592	64346885
White blood cell count decreased	36.34	14.19	30	42225	157807	64298670
Post procedural complication	35.69	14.19	56	42199	21297	64435180
Cerebrovascular accident	35.42	14.19	181	42074	137402	64319075
Drug hypersensitivity	34.96	14.19	64	42191	237751	64218726
Radius fracture	34.30	14.19	23	42232	3161	64453316
Neutrophil count decreased	34.03	14.19	5	42250	77191	64379286
Ankle fracture	34.00	14.19	45	42210	14665	64441812
Fracture nonunion	32.82	14.19	17	42238	1449	64455028
Medication error	32.79	14.19	89	42166	49877	64406600
Blood calcium abnormal	32.33	14.19	16	42239	1238	64455239
Injury associated with device	31.67	14.19	21	42234	2832	64453645
Breast cancer in situ	31.36	14.19	14	42241	858	64455619
Multiple fractures	30.75	14.19	28	42227	6012	64450465
Suicide attempt	30.39	14.19	5	42250	71002	64385475
Bone scan abnormal	30.18	14.19	9	42246	170	64456307
Product use issue	30.06	14.19	33	42222	151682	64304795
Fractured sacrum	29.88	14.19	16	42239	1459	64455018
Cervical vertebral fracture	29.88	14.19	21	42234	3114	64453363
Ulna fracture	29.58	14.19	14	42241	982	64455495
Anaphylactic reaction	29.02	14.19	5	42250	68659	64387818
Hyperkalaemia	29.00	14.19	15	42240	101114	64355363
Rhabdomyolysis	28.79	14.19	12	42243	91714	64364763
Lower respiratory tract infection	28.71	14.19	13	42242	94601	64361876
Balance disorder	28.69	14.19	120	42135	83806	64372671
Agitation	28.65	14.19	11	42244	88356	64368121
Hepatic enzyme increased	28.33	14.19	26	42229	129917	64326560
Hand deformity	27.82	14.19	4	42251	62767	64393710
Osteocalcin increased	27.72	14.19	5	42250	6	64456471
Recalled product	27.54	14.19	13	42242	906	64455571
Osteoporotic fracture	27.29	14.19	21	42234	3577	64452900
Complication associated with device	27.24	14.19	41	42214	15039	64441438
Breast cancer female	26.66	14.19	24	42231	5079	64451398
Memory impairment	26.60	14.19	119	42136	85563	64370914
Metabolic acidosis	26.25	14.19	7	42248	70951	64385526
Cardio-respiratory arrest	26.19	14.19	16	42239	98377	64358100
Calcium ionised increased	26.12	14.19	8	42247	166	64456311
Incorrect product administration duration	25.94	14.19	32	42223	9726	64446751
Hypercalciuria	25.91	14.19	10	42245	423	64456054
Product distribution issue	25.57	14.19	12	42243	826	64455651
Calcinosis	25.44	14.19	16	42239	1972	64454505
Vitamin D decreased	25.08	14.19	28	42227	7659	64448818
Neuropathy peripheral	25.05	14.19	24	42231	117501	64338976
Multiple organ dysfunction syndrome	24.96	14.19	18	42237	101395	64355082
Anaemia	24.81	14.19	146	42109	378534	64077943
Injection site irritation	24.77	14.19	19	42236	3221	64453256
Hallucination, synaesthetic	24.62	14.19	6	42249	50	64456427
Device failure	24.42	14.19	24	42231	5668	64450809
Dystrophic calcification	24.06	14.19	7	42248	121	64456356
Road traffic accident	23.50	14.19	58	42197	30687	64425790
Pericarditis	23.45	14.19	6	42249	62510	64393967
Encephalopathy	23.34	14.19	5	42250	58814	64397663
Cementoplasty	23.09	14.19	4	42251	3	64456474
Vertigo	23.07	14.19	88	42167	58923	64397554
Hip arthroplasty	22.76	14.19	46	42209	21305	64435172
Dyspnoea	22.72	14.19	333	41922	718341	63738136
Bone fissure	22.69	14.19	7	42248	149	64456328
Alanine aminotransferase increased	22.65	14.19	35	42220	138996	64317481
Fear	22.15	14.19	44	42211	20127	64436350
Weight decreased	22.11	14.19	285	41970	285454	64171023
Intentional product use issue	22.10	14.19	18	42237	95346	64361131
Wheezing	21.59	14.19	13	42242	80566	64375911
Osteonecrosis	21.31	14.19	53	42202	28176	64428301
Sternal fracture	21.30	14.19	15	42240	2232	64454245
Dementia Alzheimer's type	20.77	14.19	11	42244	981	64455496
Injection site discolouration	20.66	14.19	24	42231	6851	64449626
Depressed level of consciousness	20.64	14.19	14	42241	81422	64375055
Gammopathy	20.45	14.19	7	42248	209	64456268
Enchondromatosis	20.38	14.19	5	42250	43	64456434
Hip surgery	20.01	14.19	15	42240	2458	64454019
Urinary bladder polyp	19.93	14.19	7	42248	226	64456251
Hypokalaemia	19.56	14.19	31	42224	121872	64334605
Colon cancer	19.36	14.19	32	42223	12707	64443770
Lung neoplasm malignant	19.16	14.19	43	42212	21405	64435072
Fibula fracture	19.11	14.19	16	42239	3072	64453405
Head injury	19.10	14.19	56	42199	32786	64423691
Prosthesis implantation	19.03	14.19	5	42250	58	64456419
Sepsis	18.95	14.19	82	42173	230259	64226218
Growing pains	18.52	14.19	4	42251	18	64456459
C-reactive protein increased	18.40	14.19	21	42234	94888	64361589
Arrhythmia	18.32	14.19	76	42179	52868	64403609
Parkinson's disease	18.30	14.19	12	42243	1589	64454888
Injection site urticaria	18.24	14.19	29	42226	11152	64445325
Hyperparathyroidism	18.12	14.19	15	42240	2837	64453640
Cardiac arrest	18.04	14.19	47	42208	154017	64302460
Extraskeletal ossification	18.03	14.19	5	42250	72	64456405
Musculoskeletal chest pain	18.01	14.19	42	42213	21437	64435040
Wrong technique in device usage process	17.98	14.19	15	42240	2867	64453610
Angioedema	17.98	14.19	9	42246	61812	64394665
Glossodynia	17.96	14.19	10	42245	64686	64391791
Fatigue	17.91	14.19	628	41627	748102	63708375
Groin pain	17.83	14.19	29	42226	11364	64445113
Joint dislocation	17.69	14.19	29	42226	11436	64445041
Oxygen saturation decreased	17.43	14.19	27	42228	107149	64349328
Leukaemia	17.41	14.19	19	42236	5069	64451408
Blood bilirubin increased	17.31	14.19	8	42247	57545	64398932
General physical health deterioration	17.29	14.19	72	42183	204353	64252124
Tetany	17.18	14.19	13	42242	2159	64454318
Vein disorder	17.10	14.19	17	42238	4070	64452407
Breast calcifications	17.01	14.19	9	42246	801	64455676
Cardiac disorder	16.93	14.19	77	42178	55739	64400738
Unresponsive to stimuli	16.79	14.19	6	42249	50387	64406090
Pneumonitis	16.78	14.19	6	42249	50359	64406118
Manufacturing product shipping issue	16.74	14.19	5	42250	95	64456382
Rash maculo-papular	16.72	14.19	5	42250	47021	64409456
Gastrointestinal haemorrhage	16.56	14.19	39	42216	132273	64324204
Clavicle fracture	16.44	14.19	16	42239	3733	64452744
Back disorder	16.42	14.19	26	42229	9964	64446513
Bone cancer	16.32	14.19	11	42244	1524	64454953
Neoplasm malignant	16.22	14.19	44	42211	24644	64431833
Suicidal ideation	16.13	14.19	12	42243	66530	64389947
Delirium	16.11	14.19	13	42242	69181	64387296
Hyperglycaemia	16.10	14.19	10	42245	60958	64395519
Muscle disorder	16.09	14.19	18	42237	4933	64451544
Pleural effusion	16.08	14.19	37	42218	126522	64329955
Hyponatraemia	16.07	14.19	47	42208	148292	64308185
Aspartate aminotransferase increased	16.06	14.19	34	42221	119754	64336723
Atypical fracture	15.82	14.19	8	42247	648	64455829
Helicobacter infection	15.76	14.19	3	42252	38359	64418118
Laryngeal pain	15.73	14.19	19	42236	5649	64450828
Wrong product stored	15.70	14.19	3	42252	6	64456471
Haemoglobin decreased	15.70	14.19	70	42185	194993	64261484
Agranulocytosis	15.69	14.19	3	42252	38226	64418251
N-telopeptide urine increased	15.50	14.19	4	42251	43	64456434
Limb discomfort	15.48	14.19	46	42209	27129	64429348
Blood creatinine increased	15.46	14.19	42	42213	135740	64320737
Hypoglycaemia	15.25	14.19	22	42233	89870	64366607
Breast enlargement	15.19	14.19	10	42245	1332	64455145
Intervertebral disc compression	15.15	14.19	9	42246	1002	64455475
Pseudarthrosis	15.11	14.19	6	42249	274	64456203
Face injury	15.04	14.19	14	42241	3091	64453386
Oestrogen receptor assay positive	14.99	14.19	6	42249	280	64456197
Septic shock	14.93	14.19	29	42226	105408	64351069
Psoriasis	14.86	14.19	15	42240	71688	64384789
International normalised ratio increased	14.83	14.19	18	42237	79149	64377328
Extrasystoles	14.82	14.19	20	42235	6638	64449839
Emphysema	14.63	14.19	30	42225	14039	64442438
Hypoxia	14.53	14.19	22	42233	88127	64368350
Pain in jaw	14.49	14.19	59	42196	40696	64415781
Productive cough	14.41	14.19	16	42239	73187	64383290
Abdominal pain	14.39	14.19	133	42122	312242	64144235
Accident	14.39	14.19	20	42235	6826	64449651
Serotonin syndrome	14.29	14.19	4	42251	39278	64417199
Hepatitis	14.24	14.19	6	42249	45576	64410901
Cardiac pacemaker insertion	14.21	14.19	17	42238	5006	64451471
Transient ischaemic attack	14.19	14.19	62	42193	44120	64412357

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	H05AA02	SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS CALCIUM HOMEOSTASIS PARATHYROID HORMONES AND ANALOGUES Parathyroid hormones and analogues
FDA CS	M0015931	Parathyroid Hormone
FDA EPC	N0000180852	Parathyroid Hormone Analog
MeSH PA	D050071	Bone Density Conservation Agents
MeSH PA	D000077264	Calcium-Regulating Hormones and Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Postmenopausal osteoporosis	indication	102447009
Glucocorticoid Induced Osteoporosis	indication
Hypogonadal Osteoporosis in Males	indication
Osteitis deformans	contraindication	2089002	DOID:5408
Osteomalacia	contraindication	4598005	DOID:10573
Renal osteodystrophy	contraindication	16726004	DOID:13068
Hepatic osteodystrophy	contraindication	28193003
Rickets	contraindication	41345002	DOID:10609
Low blood pressure	contraindication	45007003
Hypercalcemia	contraindication	66931009	DOID:12678
Osteitis fibrosa cystica generalisata	contraindication	84727000	DOID:3341
Urolithiasis	contraindication	95566004
Osteosarcoma of bone	contraindication	307576001	DOID:3376
Breastfeeding (mother)	contraindication	413712001
Bone Metastases	contraindication
Malignant Bone Disease	contraindication
Radiation Therapy Involving Bone	contraindication

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	3.23	acidic
pKa2	3.31	acidic
pKa3	3.82	acidic
pKa4	4.11	acidic
pKa5	4.44	acidic
pKa6	11.68	acidic
pKa7	12.17	acidic
pKa8	12.35	acidic
pKa9	12.6	acidic
pKa10	12.63	acidic
pKa11	12.75	acidic
pKa12	12.78	acidic
pKa13	12.93	acidic
pKa14	13.16	acidic
pKa15	13.18	acidic
pKa16	13.37	acidic
pKa17	13.37	acidic
pKa18	13.44	acidic
pKa19	13.47	acidic
pKa20	13.57	acidic
pKa21	13.72	acidic
pKa22	13.72	acidic
pKa23	13.74	acidic
pKa24	13.82	acidic
pKa25	13.89	acidic
pKa26	11.47	Basic
pKa27	11.08	Basic
pKa28	10.81	Basic
pKa29	10.48	Basic
pKa30	10.09	Basic
pKa31	7.63	Basic
pKa32	7.16	Basic
pKa33	6.69	Basic
pKa34	6.21	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Bioact source	MoA source
Parathyroid hormone/parathyroid hormone-related peptide receptor	GPCR	Q03431	PTH1R_HUMAN	AGONIST	IC50	7.40	IUPHAR	CHEMBL
Parathyroid hormone 2 receptor	GPCR	P49190	PTH2R_HUMAN	AGONIST	IC50	7.80	IUPHAR
Parathyroid hormone 2 receptor	GPCR		PTH2R_RAT	AGONIST	IC50	6.30	IUPHAR
Parathyroid hormone/parathyroid hormone-related peptide receptor	GPCR		PTH1R_RAT	AGONIST	IC50	8.70	IUPHAR

External reference:

ID	Source
D03358	KEGG_DRUG
4019512	VUID
N0000147632	NUI
99294-94-7	SECONDARY_CAS_RN
4019512	VANDF
CHEBI:135983	CHEBI
CHEMBL525610	ChEMBL_ID
4448	IUPHAR_LIGAND_ID
5411	INN_ID
DB06285	DRUGBANK_ID
10T9CSU89I	UNII
155817470	PUBCHEM_CID
114260	RXNORM
17041	MMSL
336918	MMSL
d04828	MMSL
002142	NDDF
004944	NDDF
109198008	SNOMEDCT_US
398823001	SNOMEDCT_US
425438001	SNOMEDCT_US
D019379	MESH_DESCRIPTOR_UI
C0070093	UMLSCUI
CHEMBL1201549	ChEMBL_ID

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Forteo	HUMAN PRESCRIPTION DRUG LABEL	1	0002-8400	INJECTION, SOLUTION	250 ug	SUBCUTANEOUS	NDA	35 sections
teriparatide	HUMAN PRESCRIPTION DRUG LABEL	1	47781-652	INJECTION, SOLUTION	250 ug	SUBCUTANEOUS	NDA	30 sections