Stem definition | Drug id | CAS RN |
---|---|---|
4513 | 14987-04-3 |
Molecule | Description |
---|---|
Synonyms:
|
hard, porous, granular substance used in vitamin analysis, chromatography, & antibiotic processing
|
None
None
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 9, 1983 | FDA | SANOFI AVENTIS US |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hyponatraemia | 34.68 | 24.09 | 31 | 2409 | 111869 | 63374713 |
Acute kidney injury | 31.01 | 24.09 | 44 | 2396 | 263371 | 63223211 |
Coma scale abnormal | 29.44 | 24.09 | 10 | 2430 | 5143 | 63481439 |
Maternal drugs affecting foetus | 29.27 | 24.09 | 10 | 2430 | 5232 | 63481350 |
Morbid thoughts | 27.17 | 24.09 | 6 | 2434 | 617 | 63485965 |
Vomiting | 25.49 | 24.09 | 62 | 2378 | 559555 | 62927027 |
Confusional state | 24.21 | 24.09 | 37 | 2403 | 236343 | 63250239 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Appendicolith | 81.26 | 22.69 | 28 | 2332 | 8573 | 34945998 |
Blood phosphorus increased | 80.25 | 22.69 | 27 | 2333 | 7694 | 34946877 |
Appendicitis | 69.83 | 22.69 | 29 | 2331 | 14778 | 34939793 |
Cardiogenic shock | 59.26 | 22.69 | 31 | 2329 | 26587 | 34927984 |
Ventricular fibrillation | 57.66 | 22.69 | 29 | 2331 | 22925 | 34931646 |
Dry mouth | 52.90 | 22.69 | 30 | 2330 | 30135 | 34924436 |
Myasthenia gravis | 51.89 | 22.69 | 19 | 2341 | 6921 | 34947650 |
Stress | 50.06 | 22.69 | 29 | 2331 | 30318 | 34924253 |
Blood uric acid increased | 49.27 | 22.69 | 20 | 2340 | 9604 | 34944967 |
Mesothelioma | 48.13 | 22.69 | 10 | 2350 | 435 | 34954136 |
Abdominal distension | 47.73 | 22.69 | 36 | 2324 | 58456 | 34896115 |
Hyponatraemia | 42.63 | 22.69 | 39 | 2321 | 82652 | 34871919 |
Ascites | 36.50 | 22.69 | 28 | 2332 | 46543 | 34908028 |
Multiple organ dysfunction syndrome | 35.39 | 22.69 | 34 | 2326 | 76532 | 34878039 |
Blood cholesterol increased | 34.83 | 22.69 | 20 | 2340 | 20523 | 34934048 |
Vomiting | 33.79 | 22.69 | 60 | 2300 | 247561 | 34707010 |
General physical health deterioration | 28.55 | 22.69 | 39 | 2321 | 128230 | 34826341 |
Abdominal pain | 25.35 | 22.69 | 42 | 2318 | 163576 | 34790995 |
Violence-related symptom | 24.71 | 22.69 | 6 | 2354 | 530 | 34954041 |
Incorrect route of product administration | 23.95 | 22.69 | 14 | 2346 | 14831 | 34939740 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Appendicolith | 90.94 | 19.83 | 28 | 3773 | 8523 | 79732064 |
Blood phosphorus increased | 85.69 | 19.83 | 28 | 3773 | 10319 | 79730268 |
Appendicitis | 70.00 | 19.83 | 29 | 3772 | 20765 | 79719822 |
Hyponatraemia | 68.23 | 19.83 | 61 | 3740 | 177787 | 79562800 |
Ventricular fibrillation | 61.07 | 19.83 | 30 | 3771 | 31896 | 79708691 |
Cardiogenic shock | 53.38 | 19.83 | 30 | 3771 | 41884 | 79698703 |
Myasthenia gravis | 50.82 | 19.83 | 19 | 3782 | 10380 | 79730207 |
Blood uric acid increased | 49.63 | 19.83 | 20 | 3781 | 13340 | 79727247 |
Abdominal distension | 43.77 | 19.83 | 40 | 3761 | 119610 | 79620977 |
Dry mouth | 39.37 | 19.83 | 33 | 3768 | 87986 | 79652601 |
Vomiting | 39.22 | 19.83 | 93 | 3708 | 665735 | 79074852 |
Violence-related symptom | 35.53 | 19.83 | 8 | 3793 | 723 | 79739864 |
Stress | 33.86 | 19.83 | 29 | 3772 | 79583 | 79661004 |
Ascites | 33.10 | 19.83 | 28 | 3773 | 75534 | 79665053 |
Multiple organ dysfunction syndrome | 30.60 | 19.83 | 33 | 3768 | 120213 | 79620374 |
General physical health deterioration | 30.20 | 19.83 | 50 | 3751 | 275188 | 79465399 |
Morbid thoughts | 24.38 | 19.83 | 6 | 3795 | 796 | 79739791 |
Drug ineffective | 23.76 | 19.83 | 11 | 3790 | 1080902 | 78659685 |
Mesothelioma | 23.34 | 19.83 | 5 | 3796 | 359 | 79740228 |
Abdominal pain | 22.38 | 19.83 | 54 | 3747 | 389515 | 79351072 |
Coma scale abnormal | 22.28 | 19.83 | 10 | 3791 | 8668 | 79731919 |
Hyperphosphataemia | 21.81 | 19.83 | 9 | 3792 | 6367 | 79734220 |
Blood cholesterol increased | 21.32 | 19.83 | 23 | 3778 | 83697 | 79656890 |
Iron deficiency | 20.32 | 19.83 | 10 | 3791 | 10644 | 79729943 |
None
Source | Code | Description |
---|---|---|
ATC | A02AA05 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS ANTACIDS Magnesium compounds |
MeSH PA | D000863 | Antacids |
MeSH PA | D005765 | Gastrointestinal Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Peptic ulcer | indication | 13200003 | DOID:750 |
Heartburn | indication | 16331000 | |
Indigestion | indication | 162031009 | |
Gastroesophageal reflux disease | indication | 235595009 | DOID:8534 |
Gastric Hypersecretory Conditions | indication | ||
Hiatal Hernia with Reflux Esophagitis | indication | ||
Multiple endocrine adenomas | off-label use | 60549007 | |
Systemic mast cell disease | off-label use | 397016004 | DOID:349 |
Stress-Related GI Mucosal Bleeding Prevention | off-label use | ||
Hypophosphatemia | contraindication | 4996001 | |
Constipation | contraindication | 14760008 | DOID:2089 |
Fecal impaction | contraindication | 44635007 | |
Chronic heart failure | contraindication | 48447003 | |
Acute nephropathy | contraindication | 58574008 | |
Diarrhea | contraindication | 62315008 | |
Hemorrhoids | contraindication | 70153002 | DOID:9746 |
Oliguria | contraindication | 83128009 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Gastrointestinal obstruction | contraindication | 126765001 | |
Chronic diarrhea | contraindication | 236071009 | |
Aluminum intoxication | contraindication | 236546003 | |
Edema | contraindication | 267038008 |
None
None
None
None
None
None
ID | Source |
---|---|
9B9691B2N9 | UNII |
D03271 | KEGG_DRUG |
39365-87-2 | SECONDARY_CAS_RN |
4019384 | VANDF |
C0851342 | UMLSCUI |
CHEMBL2109133 | ChEMBL_ID |
66225 | PUBCHEM_CID |
DB13249 | DRUGBANK_ID |
CHEMBL2096633 | ChEMBL_ID |
C005013 | MESH_SUPPLEMENTAL_RECORD_UI |
C001671 | MESH_SUPPLEMENTAL_RECORD_UI |
DB09281 | DRUGBANK_ID |
1310566 | RXNORM |
5018 | MMSL |
5593 | MMSL |
d03587 | MMSL |
001121 | NDDF |
008286 | NDDF |
21691008 | SNOMEDCT_US |
387117008 | SNOMEDCT_US |
1343-88-0 | SECONDARY_CAS_RN |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
GavisconRegular Strength | HUMAN OTC DRUG LABEL | 2 | 0135-0096 | TABLET, CHEWABLE | 14.20 mg | ORAL | NDA | 15 sections |
GavisconRegular Strength | HUMAN OTC DRUG LABEL | 2 | 0135-0096 | TABLET, CHEWABLE | 14.20 mg | ORAL | NDA | 15 sections |
VIRUS BLOCKER CL-40 | HUMAN OTC DRUG LABEL | 1 | 80965-201 | STICK | 80 g | TOPICAL | unapproved drug other | 11 sections |