Stem definition | Drug id | CAS RN |
---|---|---|
4512 | 919-16-4 |
Molecule | Description |
---|---|
Synonyms:
|
|
Dose | Unit | Route |
---|---|---|
24 | mmol | O |
None
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 23, 1980 | FDA | ROXANE |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Toxicity to various agents | 1391.65 | 13.37 | 1279 | 46226 | 245971 | 63195546 |
Nephrogenic diabetes insipidus | 684.53 | 13.37 | 156 | 47349 | 803 | 63440714 |
Tremor | 668.15 | 13.37 | 646 | 46859 | 131593 | 63309924 |
Neuroleptic malignant syndrome | 643.85 | 13.37 | 266 | 47239 | 11790 | 63429727 |
Mania | 560.97 | 13.37 | 243 | 47262 | 12124 | 63429393 |
Drug interaction | 473.43 | 13.37 | 710 | 46795 | 228421 | 63213096 |
Hypomania | 461.71 | 13.37 | 175 | 47330 | 6155 | 63435362 |
Psychotic disorder | 429.02 | 13.37 | 257 | 47248 | 25455 | 63416062 |
Schizophrenia | 382.07 | 13.37 | 174 | 47331 | 9778 | 63431739 |
Antipsychotic drug level increased | 371.06 | 13.37 | 127 | 47378 | 3308 | 63438209 |
Completed suicide | 361.58 | 13.37 | 493 | 47012 | 145180 | 63296337 |
Extrapyramidal disorder | 345.81 | 13.37 | 178 | 47327 | 13106 | 63428411 |
Hyperparathyroidism | 314.05 | 13.37 | 106 | 47399 | 2643 | 63438874 |
Tardive dyskinesia | 299.34 | 13.37 | 140 | 47365 | 8362 | 63433155 |
Agitation | 275.30 | 13.37 | 278 | 47227 | 59479 | 63382038 |
Suicidal ideation | 266.94 | 13.37 | 279 | 47226 | 62142 | 63379375 |
Ataxia | 264.14 | 13.37 | 156 | 47349 | 15039 | 63426478 |
Catatonia | 260.19 | 13.37 | 105 | 47400 | 4372 | 63437145 |
Sedation | 256.96 | 13.37 | 221 | 47284 | 38588 | 63402929 |
Bipolar disorder | 222.69 | 13.37 | 112 | 47393 | 7848 | 63433669 |
Suicide attempt | 221.51 | 13.37 | 250 | 47255 | 60668 | 63380849 |
Jaundice cholestatic | 216.56 | 13.37 | 107 | 47398 | 7217 | 63434300 |
Serotonin syndrome | 209.76 | 13.37 | 173 | 47332 | 28509 | 63413008 |
Pain | 205.96 | 13.37 | 153 | 47352 | 740475 | 62701042 |
Akathisia | 194.15 | 13.37 | 107 | 47398 | 9039 | 63432478 |
Diabetes insipidus | 178.59 | 13.37 | 69 | 47436 | 2556 | 63438961 |
Antipsychotic drug level above therapeutic | 175.60 | 13.37 | 54 | 47451 | 989 | 63440528 |
Pleurothotonus | 173.96 | 13.37 | 57 | 47448 | 1292 | 63440225 |
Parkinsonism | 167.99 | 13.37 | 102 | 47403 | 10337 | 63431180 |
Hypernatraemia | 164.21 | 13.37 | 90 | 47415 | 7519 | 63433998 |
Overdose | 161.05 | 13.37 | 300 | 47205 | 114778 | 63326739 |
Salivary hypersecretion | 158.10 | 13.37 | 88 | 47417 | 7578 | 63433939 |
Drug level increased | 157.66 | 13.37 | 133 | 47372 | 22603 | 63418914 |
Delusion | 157.24 | 13.37 | 103 | 47402 | 11914 | 63429603 |
Delirium | 156.39 | 13.37 | 191 | 47314 | 50350 | 63391167 |
Arthralgia | 155.16 | 13.37 | 120 | 47385 | 569590 | 62871927 |
Aggression | 151.82 | 13.37 | 132 | 47373 | 23366 | 63418151 |
Confusional state | 150.72 | 13.37 | 453 | 47052 | 235927 | 63205590 |
Disorientation | 148.66 | 13.37 | 165 | 47340 | 39287 | 63402230 |
Dysarthria | 142.96 | 13.37 | 168 | 47337 | 42543 | 63398974 |
Infusion related reaction | 142.05 | 13.37 | 11 | 47494 | 245510 | 63196007 |
Systemic lupus erythematosus | 141.71 | 13.37 | 3 | 47502 | 208915 | 63232602 |
Rheumatoid arthritis | 139.74 | 13.37 | 14 | 47491 | 253805 | 63187712 |
Somnolence | 138.88 | 13.37 | 368 | 47137 | 178317 | 63263200 |
Muscle rigidity | 137.05 | 13.37 | 93 | 47412 | 11407 | 63430110 |
Arthropathy | 131.76 | 13.37 | 12 | 47493 | 234780 | 63206737 |
Hallucination, auditory | 130.18 | 13.37 | 94 | 47411 | 12730 | 63428787 |
Swelling | 128.66 | 13.37 | 25 | 47480 | 275353 | 63166164 |
Joint swelling | 127.75 | 13.37 | 43 | 47462 | 327623 | 63113894 |
Polyuria | 126.09 | 13.37 | 79 | 47426 | 8463 | 63433054 |
Irritability | 125.38 | 13.37 | 136 | 47369 | 31558 | 63409959 |
Obsessive-compulsive disorder | 122.06 | 13.37 | 60 | 47445 | 4000 | 63437517 |
Hyperreflexia | 122.04 | 13.37 | 68 | 47437 | 5866 | 63435651 |
Nasopharyngitis | 116.85 | 13.37 | 24 | 47481 | 254233 | 63187284 |
Disturbance in attention | 115.99 | 13.37 | 143 | 47362 | 38046 | 63403471 |
Glossodynia | 115.98 | 13.37 | 4 | 47501 | 178872 | 63262645 |
Myoclonus | 114.51 | 13.37 | 95 | 47410 | 15773 | 63425744 |
Mental status changes | 113.44 | 13.37 | 144 | 47361 | 39455 | 63402062 |
Intentional self-injury | 111.85 | 13.37 | 116 | 47389 | 25571 | 63415946 |
Dyspnoea | 110.07 | 13.37 | 205 | 47300 | 661108 | 62780409 |
Hypersensitivity | 109.64 | 13.37 | 41 | 47464 | 292644 | 63148873 |
Alopecia | 108.16 | 13.37 | 59 | 47446 | 337477 | 63104040 |
Intentional overdose | 107.05 | 13.37 | 196 | 47309 | 73956 | 63367561 |
Abnormal behaviour | 106.57 | 13.37 | 104 | 47401 | 21322 | 63420195 |
Paranoia | 105.93 | 13.37 | 80 | 47425 | 11599 | 63429918 |
Hypothyroidism | 103.57 | 13.37 | 143 | 47362 | 42489 | 63399028 |
Contraindicated product administered | 103.25 | 13.37 | 19 | 47486 | 217629 | 63223888 |
Depression | 99.29 | 13.37 | 348 | 47157 | 196144 | 63245373 |
Neurotoxicity | 98.93 | 13.37 | 90 | 47415 | 16900 | 63424617 |
Mental disorder | 91.82 | 13.37 | 105 | 47400 | 25814 | 63415703 |
Sinusitis | 91.37 | 13.37 | 28 | 47477 | 226625 | 63214892 |
Polydipsia | 90.54 | 13.37 | 47 | 47458 | 3517 | 63438000 |
Cholelithiasis | 90.13 | 13.37 | 136 | 47369 | 43789 | 63397728 |
Bipolar I disorder | 88.31 | 13.37 | 38 | 47467 | 1861 | 63439656 |
Electrocardiogram QT prolonged | 88.00 | 13.37 | 159 | 47346 | 59371 | 63382146 |
Drug intolerance | 86.41 | 13.37 | 63 | 47442 | 308598 | 63132919 |
Peripheral swelling | 85.86 | 13.37 | 46 | 47459 | 265896 | 63175621 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 85.32 | 13.37 | 38 | 47467 | 2023 | 63439494 |
Hepatotoxicity | 85.14 | 13.37 | 121 | 47384 | 36920 | 63404597 |
Granulocytopenia | 85.08 | 13.37 | 53 | 47452 | 5619 | 63435898 |
Abdominal discomfort | 84.13 | 13.37 | 70 | 47435 | 320815 | 63120702 |
Antipsychotic drug level below therapeutic | 83.11 | 13.37 | 23 | 47482 | 285 | 63441232 |
Fatigue | 82.97 | 13.37 | 363 | 47142 | 887665 | 62553852 |
Blood bilirubin increased | 81.96 | 13.37 | 119 | 47386 | 37021 | 63404496 |
Total lung capacity increased | 81.18 | 13.37 | 38 | 47467 | 2272 | 63439245 |
Weight increased | 80.53 | 13.37 | 397 | 47108 | 260395 | 63181122 |
Treatment noncompliance | 80.06 | 13.37 | 118 | 47387 | 37207 | 63404310 |
Hypercalcaemia | 79.54 | 13.37 | 102 | 47403 | 28220 | 63413297 |
Stomatitis | 78.02 | 13.37 | 7 | 47498 | 138718 | 63302799 |
Libido increased | 76.27 | 13.37 | 31 | 47474 | 1314 | 63440203 |
Rash | 74.21 | 13.37 | 197 | 47308 | 560674 | 62880843 |
Euphoric mood | 74.15 | 13.37 | 46 | 47459 | 4841 | 63436676 |
Camptocormia | 73.92 | 13.37 | 21 | 47484 | 288 | 63441229 |
Dyskinesia | 72.75 | 13.37 | 104 | 47401 | 31898 | 63409619 |
Dystonia | 72.35 | 13.37 | 69 | 47436 | 13750 | 63427767 |
Sopor | 72.18 | 13.37 | 86 | 47419 | 22078 | 63419439 |
Poisoning | 70.95 | 13.37 | 68 | 47437 | 13632 | 63427885 |
Mutism | 70.53 | 13.37 | 31 | 47474 | 1599 | 63439918 |
Parathyroid tumour benign | 70.39 | 13.37 | 25 | 47480 | 728 | 63440789 |
Somatic symptom disorder | 70.23 | 13.37 | 36 | 47469 | 2624 | 63438893 |
Nephropathy | 70.17 | 13.37 | 49 | 47456 | 6292 | 63435225 |
Body tinea | 69.32 | 13.37 | 32 | 47473 | 1853 | 63439664 |
Apathy | 68.39 | 13.37 | 55 | 47450 | 8739 | 63432778 |
Cogwheel rigidity | 67.97 | 13.37 | 32 | 47473 | 1938 | 63439579 |
Aphasia | 67.44 | 13.37 | 102 | 47403 | 32898 | 63408619 |
Pruritus | 67.35 | 13.37 | 104 | 47401 | 361349 | 63080168 |
Depressed mood | 66.73 | 13.37 | 113 | 47392 | 40078 | 63401439 |
Grandiosity | 65.56 | 13.37 | 19 | 47486 | 281 | 63441236 |
Anaemia | 65.30 | 13.37 | 74 | 47431 | 293356 | 63148161 |
Inhibitory drug interaction | 65.09 | 13.37 | 35 | 47470 | 2814 | 63438703 |
Drug abuse | 64.18 | 13.37 | 157 | 47348 | 72361 | 63369156 |
Blood prolactin increased | 63.59 | 13.37 | 37 | 47468 | 3466 | 63438051 |
Schizoaffective disorder | 63.01 | 13.37 | 37 | 47468 | 3525 | 63437992 |
Infection | 62.52 | 13.37 | 48 | 47457 | 229125 | 63212392 |
Restlessness | 61.56 | 13.37 | 92 | 47413 | 29361 | 63412156 |
Psychomotor hyperactivity | 61.13 | 13.37 | 56 | 47449 | 10607 | 63430910 |
Gastrointestinal disorder | 61.05 | 13.37 | 12 | 47493 | 131227 | 63310290 |
Depressed level of consciousness | 61.00 | 13.37 | 140 | 47365 | 61938 | 63379579 |
Postural tremor | 58.36 | 13.37 | 18 | 47487 | 333 | 63441184 |
Back pain | 58.35 | 13.37 | 67 | 47438 | 264078 | 63177439 |
Encephalopathy | 58.14 | 13.37 | 104 | 47401 | 38516 | 63403001 |
Chronic kidney disease | 58.06 | 13.37 | 114 | 47391 | 45284 | 63396233 |
Logorrhoea | 57.80 | 13.37 | 31 | 47474 | 2479 | 63439038 |
Treatment failure | 57.80 | 13.37 | 39 | 47466 | 199004 | 63242513 |
Pain in extremity | 57.42 | 13.37 | 100 | 47405 | 331386 | 63110131 |
Resting tremor | 57.29 | 13.37 | 22 | 47483 | 801 | 63440716 |
Hostility | 57.28 | 13.37 | 28 | 47477 | 1844 | 63439673 |
Therapeutic product effect decreased | 57.25 | 13.37 | 37 | 47468 | 193150 | 63248367 |
Brugada syndrome | 56.58 | 13.37 | 18 | 47487 | 370 | 63441147 |
Anticholinergic syndrome | 56.49 | 13.37 | 30 | 47475 | 2352 | 63439165 |
Blister | 56.09 | 13.37 | 14 | 47491 | 129800 | 63311717 |
Altered state of consciousness | 55.89 | 13.37 | 81 | 47424 | 25149 | 63416368 |
Anger | 53.76 | 13.37 | 56 | 47449 | 12400 | 63429117 |
Impaired healing | 53.02 | 13.37 | 7 | 47498 | 102535 | 63338982 |
Electrocardiogram T wave abnormal | 52.95 | 13.37 | 29 | 47476 | 2418 | 63439099 |
Pressure of speech | 52.67 | 13.37 | 20 | 47485 | 706 | 63440811 |
Tachyphrenia | 52.64 | 13.37 | 24 | 47481 | 1350 | 63440167 |
Discomfort | 52.46 | 13.37 | 30 | 47475 | 167344 | 63274173 |
Anxiety | 52.06 | 13.37 | 309 | 47196 | 217232 | 63224285 |
Mood swings | 51.67 | 13.37 | 66 | 47439 | 18182 | 63423335 |
Cough | 50.97 | 13.37 | 88 | 47417 | 292655 | 63148862 |
Personality disorder | 50.92 | 13.37 | 39 | 47466 | 5772 | 63435745 |
Product use issue | 50.82 | 13.37 | 54 | 47451 | 220466 | 63221051 |
Infection susceptibility increased | 50.55 | 13.37 | 32 | 47473 | 3489 | 63438028 |
Schizoaffective disorder bipolar type | 49.60 | 13.37 | 13 | 47492 | 129 | 63441388 |
Nasal polyps | 49.59 | 13.37 | 39 | 47466 | 6000 | 63435517 |
Stupor | 49.57 | 13.37 | 34 | 47471 | 4241 | 63437276 |
Drug reaction with eosinophilia and systemic symptoms | 49.51 | 13.37 | 90 | 47415 | 33746 | 63407771 |
Abdominal pain upper | 49.33 | 13.37 | 49 | 47456 | 206395 | 63235122 |
Myocarditis | 49.26 | 13.37 | 49 | 47456 | 10276 | 63431241 |
Febrile neutropenia | 48.85 | 13.37 | 14 | 47491 | 118435 | 63323082 |
Glucose tolerance impaired | 48.75 | 13.37 | 40 | 47465 | 6537 | 63434980 |
Leukocytosis | 48.57 | 13.37 | 77 | 47428 | 25858 | 63415659 |
Blood creatine phosphokinase increased | 48.46 | 13.37 | 84 | 47421 | 30346 | 63411171 |
Cardio-respiratory arrest | 48.02 | 13.37 | 125 | 47380 | 59834 | 63381683 |
Disease progression | 47.95 | 13.37 | 16 | 47489 | 122742 | 63318775 |
Mental impairment | 47.88 | 13.37 | 56 | 47449 | 14095 | 63427422 |
Psychiatric symptom | 47.86 | 13.37 | 36 | 47469 | 5187 | 63436330 |
Hallucination | 47.77 | 13.37 | 118 | 47387 | 54699 | 63386818 |
Hyperprolactinaemia | 47.56 | 13.37 | 32 | 47473 | 3868 | 63437649 |
Product tampering | 47.27 | 13.37 | 16 | 47489 | 402 | 63441115 |
Withdrawal syndrome | 46.94 | 13.37 | 66 | 47439 | 19931 | 63421586 |
Death | 46.80 | 13.37 | 135 | 47370 | 374246 | 63067271 |
Neurological symptom | 46.74 | 13.37 | 37 | 47468 | 5746 | 63435771 |
Action tremor | 46.54 | 13.37 | 15 | 47490 | 322 | 63441195 |
Adulterated product | 46.17 | 13.37 | 14 | 47491 | 244 | 63441273 |
Intentional product use issue | 46.04 | 13.37 | 19 | 47486 | 127873 | 63313644 |
White blood cell count increased | 46.04 | 13.37 | 108 | 47397 | 48453 | 63393064 |
Speech disorder | 45.99 | 13.37 | 97 | 47408 | 40532 | 63400985 |
Atrial fibrillation | 45.91 | 13.37 | 15 | 47490 | 116621 | 63324896 |
Psoriatic arthropathy | 45.55 | 13.37 | 7 | 47498 | 91513 | 63350004 |
Soft tissue injury | 45.48 | 13.37 | 23 | 47482 | 1629 | 63439888 |
Lethargy | 45.09 | 13.37 | 117 | 47388 | 55890 | 63385627 |
Hypothermia | 44.72 | 13.37 | 53 | 47452 | 13528 | 63427989 |
Arthritis | 43.75 | 13.37 | 16 | 47489 | 115905 | 63325612 |
Galactorrhoea | 43.41 | 13.37 | 31 | 47474 | 4124 | 63437393 |
Drooling | 43.06 | 13.37 | 30 | 47475 | 3838 | 63437679 |
Claustrophobia | 42.88 | 13.37 | 19 | 47486 | 999 | 63440518 |
Sleep-related eating disorder | 42.79 | 13.37 | 18 | 47487 | 833 | 63440684 |
Fibromyalgia | 42.77 | 13.37 | 5 | 47500 | 80415 | 63361102 |
Poor quality sleep | 42.70 | 13.37 | 63 | 47442 | 19872 | 63421645 |
Renal cyst | 42.12 | 13.37 | 45 | 47460 | 10257 | 63431260 |
Sarcoidosis | 41.99 | 13.37 | 38 | 47467 | 7084 | 63434433 |
Diarrhoea | 41.83 | 13.37 | 339 | 47166 | 715027 | 62726490 |
Amenorrhoea | 41.76 | 13.37 | 44 | 47461 | 9870 | 63431647 |
Oculogyric crisis | 41.73 | 13.37 | 22 | 47483 | 1699 | 63439818 |
Persecutory delusion | 41.67 | 13.37 | 26 | 47479 | 2764 | 63438753 |
Substance abuse | 41.55 | 13.37 | 32 | 47473 | 4775 | 63436742 |
Asterixis | 40.05 | 13.37 | 20 | 47485 | 1379 | 63440138 |
Major depression | 40.02 | 13.37 | 39 | 47466 | 7979 | 63433538 |
Urticaria | 40.01 | 13.37 | 39 | 47466 | 165763 | 63275754 |
Goitre | 39.53 | 13.37 | 34 | 47471 | 5927 | 63435590 |
Neutrophil count increased | 39.47 | 13.37 | 55 | 47450 | 16472 | 63425045 |
Drug withdrawal syndrome | 39.36 | 13.37 | 72 | 47433 | 27122 | 63414395 |
Thinking abnormal | 39.19 | 13.37 | 44 | 47461 | 10599 | 63430918 |
Rhabdomyolysis | 38.71 | 13.37 | 95 | 47410 | 43856 | 63397661 |
Hallucination, visual | 38.51 | 13.37 | 59 | 47446 | 19239 | 63422278 |
Cerebellar atrophy | 38.21 | 13.37 | 16 | 47489 | 732 | 63440785 |
Headache | 37.95 | 13.37 | 298 | 47207 | 632943 | 62808574 |
Post-traumatic neck syndrome | 37.89 | 13.37 | 22 | 47483 | 2052 | 63439465 |
Respiratory arrest | 37.02 | 13.37 | 78 | 47427 | 32567 | 63408950 |
Asthma | 37.01 | 13.37 | 25 | 47480 | 127536 | 63313981 |
Parkinsonian gait | 36.58 | 13.37 | 14 | 47491 | 505 | 63441012 |
Sternal fracture | 36.20 | 13.37 | 22 | 47483 | 2232 | 63439285 |
Clonus | 36.06 | 13.37 | 29 | 47476 | 4607 | 63436910 |
Visuospatial deficit | 36.05 | 13.37 | 7 | 47498 | 13 | 63441504 |
Enuresis | 35.98 | 13.37 | 23 | 47482 | 2550 | 63438967 |
COVID-19 | 35.82 | 13.37 | 20 | 47485 | 113083 | 63328434 |
Lower respiratory tract infection | 35.69 | 13.37 | 28 | 47477 | 132279 | 63309238 |
Cognitive disorder | 35.48 | 13.37 | 107 | 47398 | 55708 | 63385809 |
Electroencephalogram abnormal | 35.19 | 13.37 | 26 | 47479 | 3646 | 63437871 |
Muscle twitching | 34.92 | 13.37 | 57 | 47448 | 19611 | 63421906 |
Impulsive behaviour | 34.92 | 13.37 | 19 | 47486 | 1564 | 63439953 |
Blood sodium increased | 34.72 | 13.37 | 23 | 47482 | 2709 | 63438808 |
Haemodialysis | 34.68 | 13.37 | 38 | 47467 | 8909 | 63432608 |
Gastrointestinal haemorrhage | 34.58 | 13.37 | 9 | 47496 | 81167 | 63360350 |
Bronchitis | 34.26 | 13.37 | 26 | 47479 | 124909 | 63316608 |
Psychiatric decompensation | 34.23 | 13.37 | 18 | 47487 | 1383 | 63440134 |
Electrocardiogram T wave inversion | 34.15 | 13.37 | 25 | 47480 | 3456 | 63438061 |
Maternal exposure during pregnancy | 34.03 | 13.37 | 71 | 47434 | 219991 | 63221526 |
Injection site erythema | 33.98 | 13.37 | 10 | 47495 | 83164 | 63358353 |
Hyperlipidaemia | 33.78 | 13.37 | 56 | 47449 | 19515 | 63422002 |
Drug level above therapeutic | 33.07 | 13.37 | 28 | 47477 | 4777 | 63436740 |
Choreoathetosis | 32.79 | 13.37 | 13 | 47492 | 516 | 63441001 |
Insomnia | 32.25 | 13.37 | 273 | 47232 | 214979 | 63226538 |
Renal oncocytoma | 32.15 | 13.37 | 7 | 47498 | 28 | 63441489 |
Myocardial oedema | 31.60 | 13.37 | 10 | 47495 | 202 | 63441315 |
Hereditary ataxia | 31.57 | 13.37 | 7 | 47498 | 31 | 63441486 |
Acute psychosis | 31.47 | 13.37 | 21 | 47484 | 2504 | 63439013 |
Osteoarthritis | 31.45 | 13.37 | 16 | 47489 | 95327 | 63346190 |
Cardiac murmur | 31.19 | 13.37 | 46 | 47459 | 14506 | 63427011 |
Papillary thyroid cancer | 31.14 | 13.37 | 20 | 47485 | 2236 | 63439281 |
General physical health deterioration | 31.12 | 13.37 | 65 | 47440 | 201337 | 63240180 |
Affect lability | 31.05 | 13.37 | 40 | 47465 | 11111 | 63430406 |
Rhinitis allergic | 31.00 | 13.37 | 41 | 47464 | 11686 | 63429831 |
Hyperthyroidism | 30.89 | 13.37 | 46 | 47459 | 14627 | 63426890 |
Social avoidant behaviour | 30.54 | 13.37 | 22 | 47483 | 2966 | 63438551 |
Muscle injury | 30.33 | 13.37 | 6 | 47499 | 65339 | 63376178 |
Ileus paralytic | 30.26 | 13.37 | 26 | 47479 | 4525 | 63436992 |
Memory impairment | 30.19 | 13.37 | 156 | 47349 | 104102 | 63337415 |
Acute kidney injury | 29.94 | 13.37 | 315 | 47190 | 263100 | 63178417 |
Knee arthroplasty | 29.76 | 13.37 | 3 | 47502 | 54203 | 63387314 |
Neuropathy peripheral | 29.48 | 13.37 | 25 | 47480 | 113642 | 63327875 |
Bruxism | 29.45 | 13.37 | 23 | 47482 | 3502 | 63438015 |
Bradykinesia | 29.26 | 13.37 | 27 | 47478 | 5161 | 63436356 |
Behaviour disorder | 29.20 | 13.37 | 22 | 47483 | 3177 | 63438340 |
Eye movement disorder | 29.08 | 13.37 | 27 | 47478 | 5201 | 63436316 |
Mobility decreased | 28.64 | 13.37 | 29 | 47476 | 121130 | 63320387 |
Depressive symptom | 28.43 | 13.37 | 24 | 47481 | 4078 | 63437439 |
Musculoskeletal pain | 28.25 | 13.37 | 17 | 47488 | 92260 | 63349257 |
Self-injurious ideation | 28.15 | 13.37 | 20 | 47485 | 2639 | 63438878 |
Nodal rhythm | 27.96 | 13.37 | 17 | 47488 | 1726 | 63439791 |
Pulse abnormal | 27.88 | 13.37 | 19 | 47486 | 2345 | 63439172 |
Bradyphrenia | 27.68 | 13.37 | 30 | 47475 | 6950 | 63434567 |
Myoclonic epilepsy | 27.52 | 13.37 | 15 | 47490 | 1239 | 63440278 |
Brain injury | 27.45 | 13.37 | 30 | 47475 | 7013 | 63434504 |
Suspected suicide | 27.40 | 13.37 | 29 | 47476 | 6539 | 63434978 |
Mydriasis | 27.38 | 13.37 | 39 | 47466 | 11917 | 63429600 |
Purpura | 27.35 | 13.37 | 38 | 47467 | 11347 | 63430170 |
Impaired self-care | 26.86 | 13.37 | 17 | 47488 | 1853 | 63439664 |
Drug hypersensitivity | 26.44 | 13.37 | 131 | 47374 | 310556 | 63130961 |
Lung disorder | 26.34 | 13.37 | 7 | 47498 | 62254 | 63379263 |
Ammonia increased | 25.81 | 13.37 | 24 | 47481 | 4632 | 63436885 |
Chest pain | 25.42 | 13.37 | 80 | 47425 | 215879 | 63225638 |
Abdominal pain | 25.39 | 13.37 | 123 | 47382 | 293333 | 63148184 |
Hypotonia | 25.37 | 13.37 | 33 | 47472 | 9252 | 63432265 |
Ill-defined disorder | 25.11 | 13.37 | 15 | 47490 | 81740 | 63359777 |
Hallucinations, mixed | 25.06 | 13.37 | 24 | 47481 | 4805 | 63436712 |
Neuropsychiatric symptoms | 24.97 | 13.37 | 12 | 47493 | 761 | 63440756 |
Feeling guilty | 24.96 | 13.37 | 11 | 47494 | 571 | 63440946 |
Sepsis | 24.86 | 13.37 | 48 | 47457 | 153075 | 63288442 |
Differential white blood cell count abnormal | 24.78 | 13.37 | 12 | 47493 | 774 | 63440743 |
Thrombosis | 24.32 | 13.37 | 9 | 47496 | 64746 | 63376771 |
Delusion of reference | 24.31 | 13.37 | 7 | 47498 | 101 | 63441416 |
International normalised ratio abnormal | 24.29 | 13.37 | 20 | 47485 | 3284 | 63438233 |
Ideas of reference | 24.19 | 13.37 | 7 | 47498 | 103 | 63441414 |
Judgement impaired | 24.13 | 13.37 | 12 | 47493 | 820 | 63440697 |
Irritable bowel syndrome | 24.10 | 13.37 | 16 | 47489 | 82396 | 63359121 |
Cerebral atrophy | 24.09 | 13.37 | 24 | 47481 | 5042 | 63436475 |
Antidepressant drug level increased | 23.99 | 13.37 | 9 | 47496 | 307 | 63441210 |
Hypertonia | 23.98 | 13.37 | 23 | 47482 | 4614 | 63436903 |
Polyhydramnios | 23.85 | 13.37 | 17 | 47488 | 2254 | 63439263 |
Thyrotoxic crisis | 23.55 | 13.37 | 12 | 47493 | 864 | 63440653 |
Adams-Stokes syndrome | 23.52 | 13.37 | 6 | 47499 | 53 | 63441464 |
Injection site pruritus | 23.51 | 13.37 | 3 | 47502 | 45113 | 63396404 |
Anaphylactic reaction | 23.49 | 13.37 | 10 | 47495 | 66090 | 63375427 |
Hyperammonaemia | 23.44 | 13.37 | 24 | 47481 | 5208 | 63436309 |
Histrionic personality disorder | 23.42 | 13.37 | 6 | 47499 | 54 | 63441463 |
Nystagmus | 23.39 | 13.37 | 26 | 47479 | 6194 | 63435323 |
Cardiac arrest | 23.10 | 13.37 | 133 | 47372 | 92412 | 63349105 |
Cerebellar syndrome | 23.09 | 13.37 | 20 | 47485 | 3519 | 63437998 |
Muscle contractions involuntary | 23.06 | 13.37 | 17 | 47488 | 2375 | 63439142 |
Flat affect | 22.89 | 13.37 | 14 | 47491 | 1436 | 63440081 |
Urinary incontinence | 22.87 | 13.37 | 64 | 47441 | 31950 | 63409567 |
Injection site swelling | 22.86 | 13.37 | 4 | 47501 | 47568 | 63393949 |
Electroconvulsive therapy | 22.76 | 13.37 | 6 | 47499 | 61 | 63441456 |
Hyperthermia | 22.66 | 13.37 | 31 | 47474 | 9125 | 63432392 |
Injection site pain | 22.57 | 13.37 | 39 | 47466 | 129761 | 63311756 |
Refusal of treatment by patient | 22.45 | 13.37 | 24 | 47481 | 5473 | 63436044 |
Oxygen saturation decreased | 22.34 | 13.37 | 20 | 47485 | 88565 | 63352952 |
Cerebrovascular accident | 22.13 | 13.37 | 29 | 47476 | 107995 | 63333522 |
CSWS syndrome | 22.05 | 13.37 | 5 | 47500 | 25 | 63441492 |
Cardiac failure congestive | 21.99 | 13.37 | 22 | 47483 | 92411 | 63349106 |
Affective disorder | 21.93 | 13.37 | 25 | 47480 | 6121 | 63435396 |
Impaired quality of life | 21.88 | 13.37 | 38 | 47467 | 13745 | 63427772 |
Blunted affect | 21.84 | 13.37 | 8 | 47497 | 255 | 63441262 |
Nephropathy toxic | 21.82 | 13.37 | 31 | 47474 | 9448 | 63432069 |
Gestational diabetes | 21.65 | 13.37 | 29 | 47476 | 8367 | 63433150 |
Cardiac hypertrophy | 21.55 | 13.37 | 12 | 47493 | 1033 | 63440484 |
Bone pain | 21.54 | 13.37 | 7 | 47498 | 54634 | 63386883 |
Influenza | 21.45 | 13.37 | 30 | 47475 | 108692 | 63332825 |
Drug level decreased | 21.41 | 13.37 | 28 | 47477 | 7891 | 63433626 |
Staring | 21.39 | 13.37 | 14 | 47491 | 1616 | 63439901 |
Platelet count decreased | 21.02 | 13.37 | 34 | 47471 | 116088 | 63325429 |
Seizure | 20.80 | 13.37 | 170 | 47335 | 132464 | 63309053 |
Lactate pyruvate ratio increased | 20.62 | 13.37 | 6 | 47499 | 90 | 63441427 |
Coordination abnormal | 20.61 | 13.37 | 37 | 47468 | 13736 | 63427781 |
Thyroiditis | 20.41 | 13.37 | 16 | 47489 | 2450 | 63439067 |
Mucosal inflammation | 20.38 | 13.37 | 5 | 47500 | 46923 | 63394594 |
Productive cough | 20.27 | 13.37 | 11 | 47494 | 63197 | 63378320 |
Rebound psychosis | 20.14 | 13.37 | 7 | 47498 | 191 | 63441326 |
Dyspnoea exertional | 20.07 | 13.37 | 10 | 47495 | 60292 | 63381225 |
International normalised ratio increased | 20.05 | 13.37 | 5 | 47500 | 46420 | 63395097 |
Limbic encephalitis | 20.05 | 13.37 | 8 | 47497 | 323 | 63441194 |
Electrocardiogram abnormal | 19.65 | 13.37 | 29 | 47476 | 9150 | 63432367 |
Dialysis | 19.58 | 13.37 | 31 | 47474 | 10396 | 63431121 |
Hyporeflexia | 19.48 | 13.37 | 14 | 47491 | 1881 | 63439636 |
Metabolic syndrome | 19.29 | 13.37 | 13 | 47492 | 1575 | 63439942 |
Human herpesvirus 6 infection reactivation | 19.10 | 13.37 | 8 | 47497 | 366 | 63441151 |
Dysphoria | 19.09 | 13.37 | 21 | 47484 | 4945 | 63436572 |
Slow response to stimuli | 18.99 | 13.37 | 11 | 47494 | 1021 | 63440496 |
Bundle branch block right | 18.98 | 13.37 | 21 | 47484 | 4977 | 63436540 |
Toxic encephalopathy | 18.95 | 13.37 | 24 | 47481 | 6555 | 63434962 |
Arachnoid cyst | 18.94 | 13.37 | 7 | 47498 | 229 | 63441288 |
Unresponsive to stimuli | 18.88 | 13.37 | 62 | 47443 | 33754 | 63407763 |
Ear infection | 18.84 | 13.37 | 3 | 47502 | 38210 | 63403307 |
Mood altered | 18.82 | 13.37 | 37 | 47468 | 14706 | 63426811 |
Rhinorrhoea | 18.81 | 13.37 | 13 | 47492 | 65564 | 63375953 |
Lipids decreased | 18.79 | 13.37 | 4 | 47501 | 14 | 63441503 |
Borderline personality disorder | 18.63 | 13.37 | 10 | 47495 | 801 | 63440716 |
Urine osmolarity increased | 18.56 | 13.37 | 6 | 47499 | 130 | 63441387 |
Decreased appetite | 18.51 | 13.37 | 111 | 47394 | 250941 | 63190576 |
Cystitis | 18.48 | 13.37 | 9 | 47496 | 54982 | 63386535 |
Essential tremor | 18.46 | 13.37 | 11 | 47494 | 1077 | 63440440 |
Blood citric acid increased | 18.29 | 13.37 | 5 | 47500 | 59 | 63441458 |
Compulsive sexual behaviour | 18.29 | 13.37 | 5 | 47500 | 59 | 63441458 |
Oscillopsia | 18.27 | 13.37 | 6 | 47499 | 137 | 63441380 |
Negativism | 18.27 | 13.37 | 8 | 47497 | 409 | 63441108 |
Homicidal ideation | 18.14 | 13.37 | 13 | 47492 | 1739 | 63439778 |
Acquired cystic kidney disease | 18.14 | 13.37 | 5 | 47500 | 61 | 63441456 |
Pleural effusion | 18.11 | 13.37 | 26 | 47479 | 93184 | 63348333 |
Concussion | 18.07 | 13.37 | 28 | 47477 | 9216 | 63432301 |
Sluggishness | 18.07 | 13.37 | 21 | 47484 | 5248 | 63436269 |
Consciousness fluctuating | 18.00 | 13.37 | 10 | 47495 | 857 | 63440660 |
Inflammation | 17.99 | 13.37 | 21 | 47484 | 82252 | 63359265 |
Sinus bradycardia | 17.95 | 13.37 | 36 | 47469 | 14515 | 63427002 |
Antidepressant drug level above therapeutic | 17.91 | 13.37 | 8 | 47497 | 429 | 63441088 |
Skin ulcer | 17.90 | 13.37 | 5 | 47500 | 43040 | 63398477 |
Merycism | 17.75 | 13.37 | 7 | 47498 | 274 | 63441243 |
Clear cell renal cell carcinoma | 17.67 | 13.37 | 12 | 47493 | 1473 | 63440044 |
Bronchiectasis | 17.64 | 13.37 | 38 | 47467 | 16104 | 63425413 |
Suicidal behaviour | 17.39 | 13.37 | 15 | 47490 | 2624 | 63438893 |
Epileptic encephalopathy | 17.37 | 13.37 | 7 | 47498 | 290 | 63441227 |
Body mass index increased | 17.29 | 13.37 | 11 | 47494 | 1209 | 63440308 |
Flight of ideas | 17.28 | 13.37 | 8 | 47497 | 466 | 63441051 |
Compartment syndrome | 17.16 | 13.37 | 14 | 47491 | 2270 | 63439247 |
Blood pressure systolic increased | 17.12 | 13.37 | 7 | 47498 | 47390 | 63394127 |
Musculoskeletal stiffness | 16.77 | 13.37 | 76 | 47429 | 184542 | 63256975 |
Tooth injury | 16.72 | 13.37 | 11 | 47494 | 1281 | 63440236 |
Tonsillar hypertrophy | 16.67 | 13.37 | 10 | 47495 | 991 | 63440526 |
Acalculia | 16.52 | 13.37 | 3 | 47502 | 3 | 63441514 |
Paroxysmal perceptual alteration | 16.52 | 13.37 | 3 | 47502 | 3 | 63441514 |
Ascites | 16.44 | 13.37 | 5 | 47500 | 40723 | 63400794 |
Colitis | 16.22 | 13.37 | 8 | 47497 | 48520 | 63392997 |
Choluria | 16.13 | 13.37 | 6 | 47499 | 200 | 63441317 |
Paraesthesia | 15.87 | 13.37 | 62 | 47443 | 156904 | 63284613 |
Gaze palsy | 15.77 | 13.37 | 11 | 47494 | 1409 | 63440108 |
Septic shock | 15.68 | 13.37 | 16 | 47489 | 66613 | 63374904 |
Status epilepticus | 15.67 | 13.37 | 35 | 47470 | 15198 | 63426319 |
Impaired work ability | 15.62 | 13.37 | 38 | 47467 | 17437 | 63424080 |
Hypokalaemia | 15.60 | 13.37 | 34 | 47471 | 103770 | 63337747 |
Urinary retention | 15.55 | 13.37 | 54 | 47451 | 30247 | 63411270 |
Echolalia | 15.48 | 13.37 | 6 | 47499 | 224 | 63441293 |
Neonatal respiratory distress | 15.45 | 13.37 | 7 | 47498 | 388 | 63441129 |
Hyperparathyroidism primary | 15.37 | 13.37 | 7 | 47498 | 393 | 63441124 |
Malaise | 15.35 | 13.37 | 219 | 47286 | 415735 | 63025782 |
Pneumonia | 15.31 | 13.37 | 245 | 47260 | 456522 | 62984995 |
Weight decreased | 15.26 | 13.37 | 133 | 47372 | 276665 | 63164852 |
Middle insomnia | 15.26 | 13.37 | 31 | 47474 | 12612 | 63428905 |
Dysphemia | 15.24 | 13.37 | 14 | 47491 | 2661 | 63438856 |
Thrombocytopenia | 15.10 | 13.37 | 60 | 47445 | 151097 | 63290420 |
Sleep apnoea syndrome | 15.02 | 13.37 | 52 | 47453 | 29081 | 63412436 |
Haemoglobin decreased | 15.01 | 13.37 | 57 | 47448 | 145428 | 63296089 |
Joint range of motion decreased | 15.00 | 13.37 | 3 | 47502 | 32425 | 63409092 |
Cerebellar ataxia | 14.99 | 13.37 | 9 | 47496 | 893 | 63440624 |
Delusional perception | 14.97 | 13.37 | 6 | 47499 | 245 | 63441272 |
Glomerulonephritis minimal lesion | 14.88 | 13.37 | 6 | 47499 | 249 | 63441268 |
Upper respiratory tract infection | 14.87 | 13.37 | 24 | 47481 | 82023 | 63359494 |
Posture abnormal | 14.85 | 13.37 | 13 | 47492 | 2319 | 63439198 |
Pain in jaw | 14.80 | 13.37 | 7 | 47498 | 43489 | 63398028 |
Balance disorder | 14.77 | 13.37 | 111 | 47394 | 84311 | 63357206 |
Stereotypy | 14.70 | 13.37 | 7 | 47498 | 435 | 63441082 |
Hyperhidrosis | 14.69 | 13.37 | 134 | 47371 | 107702 | 63333815 |
Nuchal rigidity | 14.67 | 13.37 | 8 | 47497 | 661 | 63440856 |
Distractibility | 14.67 | 13.37 | 7 | 47498 | 437 | 63441080 |
Increased appetite | 14.57 | 13.37 | 26 | 47479 | 9604 | 63431913 |
Throat irritation | 14.53 | 13.37 | 5 | 47500 | 37642 | 63403875 |
Loss of personal independence in daily activities | 14.51 | 13.37 | 32 | 47473 | 97258 | 63344259 |
Thought insertion | 14.44 | 13.37 | 3 | 47502 | 9 | 63441508 |
Psychotic disorder due to a general medical condition | 14.42 | 13.37 | 6 | 47499 | 270 | 63441247 |
Cardiac failure | 14.41 | 13.37 | 28 | 47477 | 89114 | 63352403 |
Bone density decreased | 14.39 | 13.37 | 33 | 47472 | 14579 | 63426938 |
Unmasking of previously unidentified disease | 14.34 | 13.37 | 9 | 47496 | 967 | 63440550 |
Movement disorder | 14.21 | 13.37 | 42 | 47463 | 21619 | 63419898 |
Neutrophilia | 14.18 | 13.37 | 17 | 47488 | 4389 | 63437128 |
Restless legs syndrome | 14.18 | 13.37 | 38 | 47467 | 18493 | 63423024 |
Dry skin | 14.16 | 13.37 | 13 | 47492 | 56874 | 63384643 |
Atrioventricular block second degree | 14.10 | 13.37 | 16 | 47489 | 3898 | 63437619 |
Amimia | 14.07 | 13.37 | 4 | 47501 | 55 | 63441462 |
Abulia | 13.97 | 13.37 | 7 | 47498 | 486 | 63441031 |
Haemorrhage | 13.97 | 13.37 | 15 | 47490 | 61007 | 63380510 |
Agranulocytosis | 13.96 | 13.37 | 46 | 47459 | 25088 | 63416429 |
Radial nerve palsy | 13.83 | 13.37 | 7 | 47498 | 497 | 63441020 |
Incoherent | 13.80 | 13.37 | 17 | 47488 | 4513 | 63437004 |
Skin disorder | 13.79 | 13.37 | 51 | 47454 | 29456 | 63412061 |
Femur fracture | 13.78 | 13.37 | 7 | 47498 | 41749 | 63399768 |
Thought blocking | 13.66 | 13.37 | 5 | 47500 | 159 | 63441358 |
Urine output increased | 13.66 | 13.37 | 10 | 47495 | 1383 | 63440134 |
Melaena | 13.65 | 13.37 | 3 | 47502 | 30362 | 63411155 |
Respiratory tract infection | 13.62 | 13.37 | 7 | 47498 | 41476 | 63400041 |
Haematochezia | 13.61 | 13.37 | 12 | 47493 | 53532 | 63387985 |
Decreased activity | 13.57 | 13.37 | 20 | 47485 | 6300 | 63435217 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Toxicity to various agents | 907.15 | 14.34 | 1088 | 36183 | 199274 | 34720386 |
Neuroleptic malignant syndrome | 610.44 | 14.34 | 323 | 36948 | 17611 | 34902049 |
Mania | 505.01 | 14.34 | 232 | 37039 | 9279 | 34910381 |
Nephrogenic diabetes insipidus | 464.42 | 14.34 | 131 | 37140 | 1190 | 34918470 |
Tremor | 437.85 | 14.34 | 488 | 36783 | 82099 | 34837561 |
Antipsychotic drug level increased | 365.02 | 14.34 | 142 | 37129 | 3723 | 34915937 |
Akathisia | 327.59 | 14.34 | 164 | 37107 | 7945 | 34911715 |
Suicide attempt | 276.71 | 14.34 | 270 | 37001 | 38846 | 34880814 |
Obsessive-compulsive disorder | 271.30 | 14.34 | 128 | 37143 | 5436 | 34914224 |
Extrapyramidal disorder | 261.75 | 14.34 | 166 | 37105 | 12714 | 34906946 |
Antipsychotic drug level below therapeutic | 256.26 | 14.34 | 98 | 37173 | 2449 | 34917211 |
Psychotic disorder | 254.65 | 14.34 | 210 | 37061 | 24242 | 34895418 |
Drug interaction | 235.34 | 14.34 | 647 | 36624 | 225299 | 34694361 |
Parkinsonism | 219.99 | 14.34 | 126 | 37145 | 8012 | 34911648 |
Schizophrenia | 197.08 | 14.34 | 120 | 37151 | 8546 | 34911114 |
Serotonin syndrome | 192.64 | 14.34 | 164 | 37107 | 19769 | 34899891 |
Antipsychotic drug level above therapeutic | 189.92 | 14.34 | 65 | 37206 | 1168 | 34918492 |
Suicidal ideation | 179.04 | 14.34 | 218 | 37053 | 40170 | 34879490 |
Hallucination, auditory | 175.95 | 14.34 | 126 | 37145 | 11791 | 34907869 |
Sedation | 173.33 | 14.34 | 158 | 37113 | 20848 | 34898812 |
Euphoric mood | 173.29 | 14.34 | 95 | 37176 | 5546 | 34914114 |
Disinhibition | 168.98 | 14.34 | 78 | 37193 | 3148 | 34916512 |
Therapeutic product effect variable | 159.41 | 14.34 | 69 | 37202 | 2387 | 34917273 |
Increased appetite | 159.07 | 14.34 | 99 | 37172 | 7330 | 34912330 |
Agitation | 152.34 | 14.34 | 242 | 37029 | 57157 | 34862503 |
Aggression | 151.49 | 14.34 | 197 | 37074 | 38767 | 34880893 |
Granulocytopenia | 149.48 | 14.34 | 91 | 37180 | 6476 | 34913184 |
Weight increased | 146.49 | 14.34 | 313 | 36958 | 92720 | 34826940 |
Completed suicide | 146.29 | 14.34 | 323 | 36948 | 97845 | 34821815 |
Hypomania | 145.71 | 14.34 | 64 | 37207 | 2295 | 34917365 |
Irritability | 135.81 | 14.34 | 149 | 37122 | 24541 | 34895119 |
Diabetes insipidus | 135.51 | 14.34 | 65 | 37206 | 2863 | 34916797 |
Psychomotor hyperactivity | 126.80 | 14.34 | 95 | 37176 | 9527 | 34910133 |
Leukopenia | 113.65 | 14.34 | 224 | 37047 | 62632 | 34857028 |
Salivary hypersecretion | 113.14 | 14.34 | 85 | 37186 | 8559 | 34911101 |
Dysarthria | 112.67 | 14.34 | 161 | 37110 | 34621 | 34885039 |
Febrile neutropenia | 109.35 | 14.34 | 10 | 37261 | 136839 | 34782821 |
Dyspnoea | 107.82 | 14.34 | 147 | 37124 | 376635 | 34543025 |
Bipolar disorder | 105.05 | 14.34 | 59 | 37212 | 3610 | 34916050 |
Delusion of grandeur | 103.80 | 14.34 | 41 | 37230 | 1119 | 34918541 |
Tardive dyskinesia | 101.38 | 14.34 | 68 | 37203 | 5722 | 34913938 |
Overdose | 100.58 | 14.34 | 267 | 37004 | 90792 | 34828868 |
Neutrophil count increased | 100.45 | 14.34 | 107 | 37164 | 17039 | 34902621 |
Dyskinesia | 97.67 | 14.34 | 120 | 37151 | 22293 | 34897367 |
Muscle rigidity | 96.43 | 14.34 | 84 | 37187 | 10434 | 34909226 |
Delusion | 94.48 | 14.34 | 90 | 37181 | 12545 | 34907115 |
Abnormal behaviour | 93.53 | 14.34 | 124 | 37147 | 24845 | 34894815 |
Ataxia | 92.97 | 14.34 | 93 | 37178 | 13760 | 34905900 |
Death | 92.56 | 14.34 | 178 | 37093 | 397871 | 34521789 |
Arthralgia | 89.02 | 14.34 | 35 | 37236 | 170006 | 34749654 |
Schizoaffective disorder | 88.47 | 14.34 | 38 | 37233 | 1289 | 34918371 |
Hypernatraemia | 86.41 | 14.34 | 72 | 37199 | 8418 | 34911242 |
Priapism | 83.49 | 14.34 | 57 | 37214 | 4937 | 34914723 |
Bruxism | 81.76 | 14.34 | 39 | 37232 | 1696 | 34917964 |
Confusional state | 81.72 | 14.34 | 337 | 36934 | 143823 | 34775837 |
Catatonia | 80.81 | 14.34 | 56 | 37215 | 4969 | 34914691 |
Myoclonus | 79.46 | 14.34 | 88 | 37183 | 14637 | 34905023 |
Anaemia | 77.27 | 14.34 | 81 | 37190 | 233254 | 34686406 |
Oppositional defiant disorder | 77.04 | 14.34 | 27 | 37244 | 522 | 34919138 |
Mental status changes | 76.52 | 14.34 | 142 | 37129 | 37941 | 34881719 |
Coordination abnormal | 76.09 | 14.34 | 64 | 37207 | 7580 | 34912080 |
White blood cell count increased | 75.97 | 14.34 | 148 | 37123 | 41003 | 34878657 |
Affective disorder | 75.84 | 14.34 | 51 | 37220 | 4309 | 34915351 |
Hyperparathyroidism | 74.92 | 14.34 | 33 | 37238 | 1191 | 34918469 |
Cough | 73.62 | 14.34 | 34 | 37237 | 150106 | 34769554 |
Decreased eye contact | 71.99 | 14.34 | 25 | 37246 | 470 | 34919190 |
Delirium | 70.27 | 14.34 | 149 | 37122 | 43842 | 34875818 |
Homicidal ideation | 68.41 | 14.34 | 40 | 37231 | 2642 | 34917018 |
Myocarditis | 67.41 | 14.34 | 78 | 37193 | 13604 | 34906056 |
Pain | 66.68 | 14.34 | 72 | 37199 | 204603 | 34715057 |
Malignant neoplasm progression | 66.27 | 14.34 | 8 | 37263 | 88038 | 34831622 |
Obesity | 66.12 | 14.34 | 75 | 37196 | 12803 | 34906857 |
Dystonia | 65.86 | 14.34 | 69 | 37202 | 10776 | 34908884 |
Dyslipidaemia | 63.06 | 14.34 | 57 | 37214 | 7431 | 34912229 |
Pain in extremity | 63.02 | 14.34 | 28 | 37243 | 126485 | 34793175 |
Electrocardiogram QRS complex prolonged | 61.55 | 14.34 | 47 | 37224 | 4847 | 34914813 |
Cognitive disorder | 61.45 | 14.34 | 110 | 37161 | 28583 | 34891077 |
Treatment noncompliance | 60.53 | 14.34 | 108 | 37163 | 27992 | 34891668 |
Pneumonia | 60.05 | 14.34 | 193 | 37078 | 362434 | 34557226 |
Intentional overdose | 59.69 | 14.34 | 139 | 37132 | 43535 | 34876125 |
Hyperreflexia | 59.38 | 14.34 | 39 | 37232 | 3167 | 34916493 |
Neurotoxicity | 59.23 | 14.34 | 84 | 37187 | 17926 | 34901734 |
Pancytopenia | 57.88 | 14.34 | 15 | 37256 | 95142 | 34824518 |
Affect lability | 56.79 | 14.34 | 40 | 37231 | 3643 | 34916017 |
Restlessness | 54.96 | 14.34 | 98 | 37173 | 25384 | 34894276 |
Brugada syndrome | 53.61 | 14.34 | 23 | 37248 | 778 | 34918882 |
Depression | 53.39 | 14.34 | 225 | 37046 | 96873 | 34822787 |
Pruritus | 53.17 | 14.34 | 44 | 37227 | 141937 | 34777723 |
Dystonic tremor | 51.87 | 14.34 | 16 | 37255 | 203 | 34919457 |
Interstitial lung disease | 51.49 | 14.34 | 5 | 37266 | 65277 | 34854383 |
Prescribed overdose | 51.28 | 14.34 | 60 | 37211 | 10587 | 34909073 |
Back pain | 50.41 | 14.34 | 34 | 37237 | 121755 | 34797905 |
Clonus | 49.83 | 14.34 | 33 | 37238 | 2717 | 34916943 |
Anxiety | 49.78 | 14.34 | 224 | 37047 | 99204 | 34820456 |
Atrial fibrillation | 49.56 | 14.34 | 35 | 37236 | 122358 | 34797302 |
Hyperprolactinaemia | 49.35 | 14.34 | 27 | 37244 | 1569 | 34918091 |
Thinking abnormal | 48.33 | 14.34 | 45 | 37226 | 6092 | 34913568 |
Somnolence | 48.10 | 14.34 | 240 | 37031 | 110876 | 34808784 |
Polydipsia | 47.92 | 14.34 | 37 | 37234 | 3878 | 34915782 |
Disorientation | 46.85 | 14.34 | 107 | 37164 | 33081 | 34886579 |
Peripheral swelling | 46.67 | 14.34 | 12 | 37259 | 76529 | 34843131 |
Depressed level of consciousness | 46.60 | 14.34 | 125 | 37146 | 42716 | 34876944 |
General physical health deterioration | 46.49 | 14.34 | 41 | 37230 | 128228 | 34791432 |
Lethargy | 45.76 | 14.34 | 121 | 37150 | 41001 | 34878659 |
Speech disorder | 45.72 | 14.34 | 91 | 37180 | 25595 | 34894065 |
Rhinalgia | 44.59 | 14.34 | 22 | 37249 | 1031 | 34918629 |
Failure to suspend medication | 44.58 | 14.34 | 17 | 37254 | 421 | 34919239 |
Rash | 43.05 | 14.34 | 110 | 37161 | 222642 | 34697018 |
Mental disorder | 42.89 | 14.34 | 66 | 37205 | 15143 | 34904517 |
Sepsis | 42.58 | 14.34 | 70 | 37201 | 166491 | 34753169 |
Septic shock | 42.40 | 14.34 | 12 | 37259 | 71822 | 34847838 |
Disease progression | 42.33 | 14.34 | 32 | 37239 | 108045 | 34811615 |
Thrombocytopenia | 41.51 | 14.34 | 64 | 37207 | 156183 | 34763477 |
Choreoathetosis | 41.43 | 14.34 | 21 | 37250 | 1043 | 34918617 |
Oedema peripheral | 41.40 | 14.34 | 40 | 37231 | 119772 | 34799888 |
Blood creatine phosphokinase increased | 41.09 | 14.34 | 123 | 37148 | 44734 | 34874926 |
Cardiac failure congestive | 40.56 | 14.34 | 19 | 37252 | 83251 | 34836409 |
Insomnia | 40.50 | 14.34 | 218 | 37053 | 103689 | 34815971 |
Electrocardiogram QT prolonged | 40.10 | 14.34 | 115 | 37156 | 40837 | 34878823 |
Enuresis | 39.67 | 14.34 | 27 | 37244 | 2326 | 34917334 |
Infusion related reaction | 39.48 | 14.34 | 5 | 37266 | 53052 | 34866608 |
Abulia | 39.40 | 14.34 | 17 | 37254 | 583 | 34919077 |
Leukocytosis | 38.97 | 14.34 | 82 | 37189 | 23983 | 34895677 |
Mental impairment | 38.23 | 14.34 | 51 | 37220 | 10271 | 34909389 |
Paranoia | 37.79 | 14.34 | 55 | 37216 | 12013 | 34907647 |
Drug level above therapeutic | 36.99 | 14.34 | 33 | 37238 | 4228 | 34915432 |
Blood thyroid stimulating hormone decreased | 36.89 | 14.34 | 24 | 37247 | 1917 | 34917743 |
Apathy | 36.65 | 14.34 | 41 | 37230 | 6891 | 34912769 |
Antipsychotic drug level decreased | 36.50 | 14.34 | 19 | 37252 | 998 | 34918662 |
Hypothyroidism | 35.94 | 14.34 | 73 | 37198 | 20829 | 34898831 |
Fatigue | 35.82 | 14.34 | 240 | 37031 | 370413 | 34549247 |
Pressure of speech | 35.74 | 14.34 | 15 | 37256 | 480 | 34919180 |
Nephropathy | 34.77 | 14.34 | 37 | 37234 | 5880 | 34913780 |
Grandiosity | 34.36 | 14.34 | 13 | 37258 | 315 | 34919345 |
Hyperparathyroidism primary | 34.22 | 14.34 | 11 | 37260 | 161 | 34919499 |
Plasma cell myeloma | 33.73 | 14.34 | 3 | 37268 | 42034 | 34877626 |
Trismus | 33.68 | 14.34 | 25 | 37246 | 2470 | 34917190 |
Joint swelling | 33.55 | 14.34 | 11 | 37260 | 59879 | 34859781 |
Distractibility | 32.70 | 14.34 | 13 | 37258 | 361 | 34919299 |
Depressed mood | 32.66 | 14.34 | 67 | 37204 | 19250 | 34900410 |
Bipolar I disorder | 32.01 | 14.34 | 16 | 37255 | 771 | 34918889 |
Myocardial infarction | 31.76 | 14.34 | 50 | 37221 | 121035 | 34798625 |
Hyperkinesia | 31.51 | 14.34 | 21 | 37250 | 1747 | 34917913 |
Decreased appetite | 31.48 | 14.34 | 83 | 37188 | 166309 | 34753351 |
Leukaemia | 31.06 | 14.34 | 31 | 37240 | 4572 | 34915088 |
Ascites | 31 | 14.34 | 6 | 37265 | 46565 | 34873095 |
Cardiac failure | 30.89 | 14.34 | 31 | 37240 | 91217 | 34828443 |
Thrombosis | 30.58 | 14.34 | 8 | 37263 | 50450 | 34869210 |
Headache | 30.24 | 14.34 | 111 | 37160 | 200524 | 34719136 |
Logorrhoea | 29.85 | 14.34 | 23 | 37248 | 2403 | 34917257 |
Drug level increased | 29.82 | 14.34 | 70 | 37201 | 22026 | 34897634 |
Muscle spasms | 29.62 | 14.34 | 22 | 37249 | 74979 | 34844681 |
Infection | 29.53 | 14.34 | 32 | 37239 | 90883 | 34828777 |
Flight of ideas | 29.16 | 14.34 | 12 | 37259 | 365 | 34919295 |
Epistaxis | 28.81 | 14.34 | 13 | 37258 | 58238 | 34861422 |
Lymphocyte count abnormal | 28.28 | 14.34 | 17 | 37254 | 1181 | 34918479 |
Eosinophil count decreased | 27.99 | 14.34 | 18 | 37253 | 1410 | 34918250 |
Sexual dysfunction | 27.85 | 14.34 | 34 | 37237 | 6269 | 34913391 |
Abdominal pain | 27.73 | 14.34 | 86 | 37185 | 163532 | 34756128 |
Therapeutic product effect incomplete | 27.65 | 14.34 | 117 | 37154 | 50424 | 34869236 |
Disturbance in attention | 27.50 | 14.34 | 75 | 37196 | 25870 | 34893790 |
Anger | 27.30 | 14.34 | 47 | 37224 | 11837 | 34907823 |
Intentional product use issue | 27.10 | 14.34 | 15 | 37256 | 59801 | 34859859 |
Patient restraint | 27.06 | 14.34 | 8 | 37263 | 87 | 34919573 |
Blood prolactin increased | 26.87 | 14.34 | 19 | 37252 | 1741 | 34917919 |
Diabetes mellitus | 26.81 | 14.34 | 110 | 37161 | 46763 | 34872897 |
Polyuria | 26.73 | 14.34 | 39 | 37232 | 8535 | 34911125 |
Prostate cancer | 26.62 | 14.34 | 5 | 37266 | 39644 | 34880016 |
Blood sodium increased | 26.61 | 14.34 | 23 | 37248 | 2825 | 34916835 |
Tachycardia | 26.61 | 14.34 | 168 | 37103 | 84604 | 34835056 |
Blunted affect | 26.30 | 14.34 | 11 | 37260 | 349 | 34919311 |
Psychiatric decompensation | 26.00 | 14.34 | 23 | 37248 | 2914 | 34916746 |
Defect conduction intraventricular | 25.95 | 14.34 | 11 | 37260 | 361 | 34919299 |
Erythema | 25.89 | 14.34 | 34 | 37237 | 88746 | 34830914 |
Gastrointestinal haemorrhage | 25.69 | 14.34 | 34 | 37237 | 88443 | 34831217 |
Diarrhoea | 25.31 | 14.34 | 280 | 36991 | 389632 | 34530028 |
Coronary artery disease | 25.14 | 14.34 | 10 | 37261 | 48295 | 34871365 |
Acute myocardial infarction | 25.02 | 14.34 | 13 | 37258 | 53706 | 34865954 |
Crying | 24.90 | 14.34 | 31 | 37240 | 5831 | 34913829 |
Abdominal distension | 24.63 | 14.34 | 16 | 37255 | 58476 | 34861184 |
Angioedema | 24.49 | 14.34 | 5 | 37266 | 37369 | 34882291 |
Haemoptysis | 24.41 | 14.34 | 4 | 37267 | 35002 | 34884658 |
Cerebral haemorrhage | 24.34 | 14.34 | 4 | 37267 | 34933 | 34884727 |
Diabetic coma | 24.24 | 14.34 | 14 | 37257 | 903 | 34918757 |
Feelings of worthlessness | 24.15 | 14.34 | 10 | 37261 | 309 | 34919351 |
Mood altered | 24.06 | 14.34 | 38 | 37233 | 8914 | 34910746 |
Cogwheel rigidity | 23.96 | 14.34 | 16 | 37255 | 1336 | 34918324 |
Blood triglycerides increased | 23.80 | 14.34 | 49 | 37222 | 14110 | 34905550 |
Cerebellar syndrome | 23.77 | 14.34 | 20 | 37251 | 2368 | 34917292 |
Urticaria | 23.73 | 14.34 | 19 | 37252 | 62358 | 34857302 |
Seizure | 23.72 | 14.34 | 192 | 37079 | 104665 | 34814995 |
Weight decreased | 23.72 | 14.34 | 102 | 37169 | 176199 | 34743461 |
Oxygen saturation decreased | 23.66 | 14.34 | 14 | 37257 | 53804 | 34865856 |
Sleep disorder | 23.64 | 14.34 | 81 | 37190 | 31607 | 34888053 |
Pneumonitis | 23.33 | 14.34 | 4 | 37267 | 33874 | 34885786 |
Drooling | 23.23 | 14.34 | 23 | 37248 | 3359 | 34916301 |
Arthritis | 23.20 | 14.34 | 3 | 37268 | 31343 | 34888317 |
Self-injurious ideation | 23.01 | 14.34 | 17 | 37254 | 1667 | 34917993 |
Pleural effusion | 23 | 14.34 | 32 | 37239 | 81514 | 34838146 |
Long QT syndrome | 22.94 | 14.34 | 21 | 37250 | 2782 | 34916878 |
Productive cough | 22.90 | 14.34 | 6 | 37265 | 37807 | 34881853 |
Oromandibular dystonia | 22.81 | 14.34 | 11 | 37260 | 490 | 34919170 |
Psychotic symptom | 22.49 | 14.34 | 17 | 37254 | 1726 | 34917934 |
Metabolic encephalopathy | 22.03 | 14.34 | 25 | 37246 | 4267 | 34915393 |
Haemorrhage | 21.70 | 14.34 | 14 | 37257 | 51356 | 34868304 |
Conduction disorder | 21.69 | 14.34 | 18 | 37253 | 2092 | 34917568 |
Musculoskeletal pain | 21.52 | 14.34 | 4 | 37267 | 31959 | 34887701 |
Chest discomfort | 21.52 | 14.34 | 16 | 37255 | 54514 | 34865146 |
Hypersensitivity | 21.51 | 14.34 | 20 | 37251 | 61015 | 34858645 |
Renal cyst | 20.93 | 14.34 | 36 | 37235 | 9057 | 34910603 |
Otospondylomegaepiphyseal dysplasia | 20.92 | 14.34 | 7 | 37264 | 117 | 34919543 |
Melaena | 20.71 | 14.34 | 6 | 37265 | 35374 | 34884286 |
Metabolic syndrome | 20.67 | 14.34 | 16 | 37255 | 1683 | 34917977 |
Autonomic nervous system imbalance | 20.66 | 14.34 | 19 | 37252 | 2532 | 34917128 |
Agranulocytosis | 20.57 | 14.34 | 64 | 37207 | 23757 | 34895903 |
Stupor | 20.49 | 14.34 | 20 | 37251 | 2871 | 34916789 |
High-grade B-cell lymphoma | 20.34 | 14.34 | 7 | 37264 | 128 | 34919532 |
Persistent depressive disorder | 20.25 | 14.34 | 9 | 37262 | 332 | 34919328 |
Stomatitis | 20.23 | 14.34 | 10 | 37261 | 42504 | 34877156 |
Hyperammonaemic encephalopathy | 20.18 | 14.34 | 18 | 37253 | 2306 | 34917354 |
Wrong patient received product | 20.01 | 14.34 | 19 | 37252 | 2635 | 34917025 |
Cerebral amyloid angiopathy | 19.99 | 14.34 | 7 | 37264 | 135 | 34919525 |
Hepatic failure | 19.94 | 14.34 | 6 | 37265 | 34525 | 34885135 |
Anaphylactic reaction | 19.80 | 14.34 | 5 | 37266 | 32296 | 34887364 |
Hyperkalaemia | 19.80 | 14.34 | 27 | 37244 | 69362 | 34850298 |
Multiple organ dysfunction syndrome | 19.70 | 14.34 | 32 | 37239 | 76534 | 34843126 |
Cerebrovascular accident | 19.52 | 14.34 | 38 | 37233 | 84773 | 34834887 |
Poor quality sleep | 19.42 | 14.34 | 33 | 37238 | 8223 | 34911437 |
Dyspnoea exertional | 19.39 | 14.34 | 11 | 37260 | 43268 | 34876392 |
Dysphemia | 19.36 | 14.34 | 15 | 37256 | 1580 | 34918080 |
Antipsychotic drug level | 19.34 | 14.34 | 4 | 37267 | 7 | 34919653 |
Oncocytoma | 19.34 | 14.34 | 4 | 37267 | 7 | 34919653 |
Mutism | 19.34 | 14.34 | 12 | 37259 | 883 | 34918777 |
Accidental death | 19.32 | 14.34 | 18 | 37253 | 2438 | 34917222 |
Convulsive threshold lowered | 19.16 | 14.34 | 10 | 37261 | 528 | 34919132 |
Restless legs syndrome | 19.13 | 14.34 | 33 | 37238 | 8321 | 34911339 |
Speech sound disorder | 19.13 | 14.34 | 7 | 37264 | 154 | 34919506 |
Memory impairment | 19.02 | 14.34 | 94 | 37177 | 43224 | 34876436 |
Intentional self-injury | 18.99 | 14.34 | 44 | 37227 | 13727 | 34905933 |
Arthropathy | 18.92 | 14.34 | 3 | 37268 | 26904 | 34892756 |
Staphylococcal infection | 18.37 | 14.34 | 6 | 37265 | 32754 | 34886906 |
Gait disturbance | 18.23 | 14.34 | 154 | 37117 | 84986 | 34834674 |
Kidney enlargement | 18.08 | 14.34 | 11 | 37260 | 781 | 34918879 |
Nephrolithiasis | 18.02 | 14.34 | 5 | 37266 | 30328 | 34889332 |
Secondary tic | 17.85 | 14.34 | 4 | 37267 | 12 | 34919648 |
Upper gastrointestinal haemorrhage | 17.60 | 14.34 | 3 | 37268 | 25515 | 34894145 |
Pyrexia | 17.50 | 14.34 | 250 | 37021 | 332763 | 34586897 |
Altered state of consciousness | 17.50 | 14.34 | 59 | 37212 | 22834 | 34896826 |
Hallucination, olfactory | 17.45 | 14.34 | 7 | 37264 | 199 | 34919461 |
Withdrawal syndrome | 17.40 | 14.34 | 40 | 37231 | 12415 | 34907245 |
Libido increased | 17.36 | 14.34 | 11 | 37260 | 840 | 34918820 |
Blood thyroid stimulating hormone increased | 17.28 | 14.34 | 22 | 37249 | 4233 | 34915427 |
Drug ineffective | 17.19 | 14.34 | 621 | 36650 | 456130 | 34463530 |
Angina pectoris | 17.14 | 14.34 | 6 | 37265 | 31357 | 34888303 |
Bone marrow failure | 17.05 | 14.34 | 5 | 37266 | 29248 | 34890412 |
Schizoaffective disorder bipolar type | 16.93 | 14.34 | 6 | 37265 | 120 | 34919540 |
Drug hypersensitivity | 16.92 | 14.34 | 38 | 37233 | 80491 | 34839169 |
Social anxiety disorder | 16.90 | 14.34 | 8 | 37263 | 342 | 34919318 |
Herpes zoster | 16.51 | 14.34 | 8 | 37263 | 34391 | 34885269 |
Dysphoria | 16.45 | 14.34 | 16 | 37255 | 2286 | 34917374 |
Thought blocking | 16.35 | 14.34 | 6 | 37265 | 133 | 34919527 |
Bipolar II disorder | 16.07 | 14.34 | 4 | 37267 | 21 | 34919639 |
Drug withdrawal syndrome | 15.95 | 14.34 | 52 | 37219 | 19782 | 34899878 |
Gastrectomy | 15.83 | 14.34 | 6 | 37265 | 146 | 34919514 |
Toxic cardiomyopathy | 15.70 | 14.34 | 7 | 37264 | 260 | 34919400 |
Bronchitis | 15.69 | 14.34 | 13 | 37258 | 41950 | 34877710 |
Urinary incontinence | 15.64 | 14.34 | 50 | 37221 | 18824 | 34900836 |
Haematoma | 15.63 | 14.34 | 4 | 37267 | 25601 | 34894059 |
Electrocardiogram abnormal | 15.54 | 14.34 | 32 | 37239 | 9215 | 34910445 |
Acarodermatitis | 15.49 | 14.34 | 8 | 37263 | 413 | 34919247 |
Cerebral infarction | 15.44 | 14.34 | 5 | 37266 | 27450 | 34892210 |
Muscle twitching | 15.42 | 14.34 | 34 | 37237 | 10264 | 34909396 |
Impulsive behaviour | 15.40 | 14.34 | 15 | 37256 | 2147 | 34917513 |
Metastases to eye | 15.32 | 14.34 | 5 | 37266 | 77 | 34919583 |
Blood pressure fluctuation | 15.30 | 14.34 | 4 | 37267 | 25245 | 34894415 |
Sinusitis | 15.26 | 14.34 | 13 | 37258 | 41389 | 34878271 |
Hypoxia | 15.15 | 14.34 | 22 | 37249 | 55073 | 34864587 |
Encephalopathy | 15.05 | 14.34 | 76 | 37195 | 35243 | 34884417 |
International normalised ratio increased | 14.98 | 14.34 | 17 | 37254 | 47310 | 34872350 |
Abdominal pain upper | 14.80 | 14.34 | 34 | 37237 | 71456 | 34848204 |
Electroconvulsive therapy | 14.74 | 14.34 | 4 | 37267 | 31 | 34919629 |
Paradoxical drug reaction | 14.68 | 14.34 | 18 | 37253 | 3333 | 34916327 |
Neutrophilia | 14.65 | 14.34 | 20 | 37251 | 4117 | 34915543 |
Coma | 14.61 | 14.34 | 91 | 37180 | 45587 | 34874073 |
Blood creatinine increased | 14.50 | 14.34 | 160 | 37111 | 94816 | 34824844 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Toxicity to various agents | 2032.27 | 13.02 | 2167 | 68772 | 419373 | 79254076 |
Neuroleptic malignant syndrome | 1128.39 | 13.02 | 531 | 70408 | 27028 | 79646421 |
Nephrogenic diabetes insipidus | 1056.05 | 13.02 | 267 | 70672 | 1867 | 79671582 |
Tremor | 1007.08 | 13.02 | 980 | 69959 | 169103 | 79504346 |
Mania | 828.81 | 13.02 | 378 | 70561 | 17882 | 79655567 |
Drug interaction | 666.16 | 13.02 | 1264 | 69675 | 413919 | 79259530 |
Antipsychotic drug level increased | 631.57 | 13.02 | 227 | 70712 | 5730 | 79667719 |
Psychotic disorder | 579.90 | 13.02 | 395 | 70544 | 41007 | 79632442 |
Hypomania | 568.81 | 13.02 | 224 | 70715 | 7320 | 79666129 |
Extrapyramidal disorder | 563.21 | 13.02 | 312 | 70627 | 22367 | 79651082 |
Schizophrenia | 533.52 | 13.02 | 265 | 70674 | 15175 | 79658274 |
Completed suicide | 482.52 | 13.02 | 818 | 70121 | 244949 | 79428500 |
Hyperparathyroidism | 395.69 | 13.02 | 137 | 70802 | 3087 | 79670362 |
Serotonin syndrome | 391.85 | 13.02 | 323 | 70616 | 44704 | 79628745 |
Agitation | 376.93 | 13.02 | 454 | 70485 | 99261 | 79574188 |
Suicidal ideation | 362.10 | 13.02 | 391 | 70548 | 75949 | 79597500 |
Ataxia | 360.30 | 13.02 | 243 | 70696 | 24796 | 79648653 |
Akathisia | 355.67 | 13.02 | 192 | 70747 | 13067 | 79660382 |
Antipsychotic drug level above therapeutic | 345.39 | 13.02 | 111 | 70828 | 1969 | 79671480 |
Suicide attempt | 340.58 | 13.02 | 394 | 70545 | 82538 | 79590911 |
Sedation | 328.92 | 13.02 | 311 | 70628 | 51584 | 79621865 |
Parkinsonism | 325.97 | 13.02 | 196 | 70743 | 16388 | 79657061 |
Tardive dyskinesia | 311.55 | 13.02 | 163 | 70776 | 10408 | 79663041 |
Catatonia | 283.98 | 13.02 | 144 | 70795 | 8612 | 79664837 |
Diabetes insipidus | 281.12 | 13.02 | 122 | 70817 | 5115 | 79668334 |
Obsessive-compulsive disorder | 269.78 | 13.02 | 123 | 70816 | 5804 | 79667645 |
Hallucination, auditory | 258.20 | 13.02 | 184 | 70755 | 20509 | 79652940 |
Aggression | 253.92 | 13.02 | 268 | 70671 | 50690 | 79622759 |
Salivary hypersecretion | 251.18 | 13.02 | 157 | 70782 | 14067 | 79659382 |
Bipolar disorder | 241.95 | 13.02 | 124 | 70815 | 7583 | 79665866 |
Pain | 241.23 | 13.02 | 166 | 70773 | 703636 | 78969813 |
Granulocytopenia | 234.79 | 13.02 | 139 | 70800 | 11292 | 79662157 |
Dysarthria | 226.69 | 13.02 | 290 | 70649 | 67332 | 79606117 |
Irritability | 224.10 | 13.02 | 227 | 70712 | 40917 | 79632532 |
Arthralgia | 223.77 | 13.02 | 115 | 70824 | 571688 | 79101761 |
Hypernatraemia | 219.31 | 13.02 | 145 | 70794 | 14306 | 79659143 |
Muscle rigidity | 219.08 | 13.02 | 164 | 70775 | 19718 | 79653731 |
Overdose | 216.87 | 13.02 | 495 | 70444 | 183711 | 79489738 |
Dyspnoea | 211.76 | 13.02 | 272 | 70667 | 856753 | 78816696 |
Delirium | 210.12 | 13.02 | 314 | 70625 | 84313 | 79589136 |
Confusional state | 205.72 | 13.02 | 686 | 70253 | 317311 | 79356138 |
Psychomotor hyperactivity | 194.65 | 13.02 | 143 | 70796 | 16706 | 79656743 |
Delusion | 180.73 | 13.02 | 148 | 70791 | 20275 | 79653174 |
Hyperreflexia | 180.20 | 13.02 | 105 | 70834 | 8280 | 79665169 |
Mental status changes | 178.58 | 13.02 | 257 | 70682 | 66702 | 79606747 |
Antipsychotic drug level below therapeutic | 173.03 | 13.02 | 58 | 70881 | 1180 | 79672269 |
Myoclonus | 168.05 | 13.02 | 162 | 70777 | 27498 | 79645951 |
Jaundice cholestatic | 161.07 | 13.02 | 109 | 70830 | 11175 | 79662274 |
Disorientation | 160.21 | 13.02 | 236 | 70703 | 62540 | 79610909 |
Somnolence | 155.69 | 13.02 | 517 | 70422 | 238464 | 79434985 |
Neurotoxicity | 154.85 | 13.02 | 167 | 70772 | 32351 | 79641098 |
Abnormal behaviour | 154.40 | 13.02 | 176 | 70763 | 36245 | 79637204 |
Intentional overdose | 150.08 | 13.02 | 307 | 70632 | 105653 | 79567796 |
Drug level increased | 148.79 | 13.02 | 180 | 70759 | 39471 | 79633978 |
Infusion related reaction | 148.27 | 13.02 | 16 | 70923 | 230221 | 79443228 |
Rheumatoid arthritis | 146.47 | 13.02 | 10 | 70929 | 208460 | 79464989 |
Dystonia | 144.68 | 13.02 | 133 | 70806 | 21266 | 79652183 |
Euphoric mood | 143.30 | 13.02 | 88 | 70851 | 7638 | 79665811 |
Dyskinesia | 134.50 | 13.02 | 182 | 70757 | 44591 | 79628858 |
Joint swelling | 133.72 | 13.02 | 45 | 70894 | 288601 | 79384848 |
Polyuria | 133.25 | 13.02 | 109 | 70830 | 14905 | 79658544 |
Schizoaffective disorder | 128.27 | 13.02 | 54 | 70885 | 2098 | 79671351 |
Febrile neutropenia | 128.06 | 13.02 | 25 | 70914 | 230974 | 79442475 |
Hypothyroidism | 128 | 13.02 | 193 | 70746 | 52199 | 79621250 |
Anaemia | 127.30 | 13.02 | 125 | 70814 | 444890 | 79228559 |
Disturbance in attention | 123.91 | 13.02 | 187 | 70752 | 50614 | 79622835 |
Pleurothotonus | 120.16 | 13.02 | 54 | 70885 | 2462 | 79670987 |
Synovitis | 119.81 | 13.02 | 3 | 70936 | 150731 | 79522718 |
Hypersensitivity | 119.53 | 13.02 | 42 | 70897 | 262197 | 79411252 |
Neutrophil count increased | 119.46 | 13.02 | 139 | 70800 | 29257 | 79644192 |
Pruritus | 118.56 | 13.02 | 106 | 70833 | 394542 | 79278907 |
Arthropathy | 117.43 | 13.02 | 11 | 70928 | 177100 | 79496349 |
Delusion of grandeur | 116.69 | 13.02 | 45 | 70894 | 1387 | 79672062 |
Cough | 115.69 | 13.02 | 94 | 70845 | 366695 | 79306754 |
Weight increased | 114.91 | 13.02 | 520 | 70419 | 276866 | 79396583 |
Treatment noncompliance | 114.36 | 13.02 | 183 | 70756 | 52085 | 79621364 |
Swelling | 112.90 | 13.02 | 27 | 70912 | 216684 | 79456765 |
Polydipsia | 111.83 | 13.02 | 71 | 70868 | 6534 | 79666915 |
Peripheral swelling | 111.70 | 13.02 | 50 | 70889 | 269567 | 79403882 |
Nasopharyngitis | 110.11 | 13.02 | 44 | 70895 | 253837 | 79419612 |
Brugada syndrome | 108.41 | 13.02 | 41 | 70898 | 1197 | 79672252 |
Rash | 108.21 | 13.02 | 220 | 70719 | 578138 | 79095311 |
Pain in extremity | 108.18 | 13.02 | 99 | 70840 | 364439 | 79309010 |
Depression | 107.25 | 13.02 | 429 | 70510 | 216361 | 79457088 |
Paranoia | 107.22 | 13.02 | 108 | 70831 | 19324 | 79654125 |
Depressed level of consciousness | 106.23 | 13.02 | 253 | 70686 | 96399 | 79577050 |
Nephropathy | 102.12 | 13.02 | 78 | 70861 | 9660 | 79663789 |
Bruxism | 101.58 | 13.02 | 56 | 70883 | 3970 | 79669479 |
Malignant neoplasm progression | 100.14 | 13.02 | 5 | 70934 | 135985 | 79537464 |
Mental disorder | 99.78 | 13.02 | 131 | 70808 | 31171 | 79642278 |
Restlessness | 97.92 | 13.02 | 160 | 70779 | 46332 | 79627117 |
Back pain | 97.08 | 13.02 | 77 | 70862 | 304103 | 79369346 |
Electrocardiogram QT prolonged | 96.54 | 13.02 | 234 | 70705 | 90152 | 79583297 |
Bipolar I disorder | 96.31 | 13.02 | 44 | 70895 | 2085 | 79671364 |
Intentional self-injury | 96.18 | 13.02 | 131 | 70808 | 32288 | 79641161 |
Systemic lupus erythematosus | 94.11 | 13.02 | 3 | 70936 | 121146 | 79552303 |
Sinusitis | 93.12 | 13.02 | 29 | 70910 | 195472 | 79477977 |
Myocarditis | 92.06 | 13.02 | 105 | 70834 | 21628 | 79651821 |
Apathy | 90.34 | 13.02 | 82 | 70857 | 12895 | 79660554 |
Cognitive disorder | 90.13 | 13.02 | 195 | 70744 | 69731 | 79603718 |
Stomatitis | 90.01 | 13.02 | 12 | 70927 | 146745 | 79526704 |
Leukocytosis | 89.43 | 13.02 | 148 | 70791 | 43307 | 79630142 |
Clonus | 88.03 | 13.02 | 62 | 70877 | 6778 | 79666671 |
White blood cell count increased | 87.07 | 13.02 | 200 | 70739 | 74433 | 79599016 |
Priapism | 85.30 | 13.02 | 52 | 70887 | 4453 | 79668996 |
Grandiosity | 84.02 | 13.02 | 28 | 70911 | 559 | 79672890 |
Cogwheel rigidity | 83.59 | 13.02 | 45 | 70894 | 3043 | 79670406 |
Interstitial lung disease | 83.35 | 13.02 | 4 | 70935 | 112596 | 79560853 |
Libido increased | 83.18 | 13.02 | 39 | 70900 | 1962 | 79671487 |
Leukopenia | 82.94 | 13.02 | 260 | 70679 | 116253 | 79557196 |
Blood creatine phosphokinase increased | 82.56 | 13.02 | 182 | 70757 | 65908 | 79607541 |
Affect lability | 82.04 | 13.02 | 73 | 70866 | 11186 | 79662263 |
Speech disorder | 80.92 | 13.02 | 161 | 70778 | 54284 | 79619165 |
Oppositional defiant disorder | 80.38 | 13.02 | 26 | 70913 | 471 | 79672978 |
Infection | 79.90 | 13.02 | 59 | 70880 | 241653 | 79431796 |
Arthritis | 79.25 | 13.02 | 6 | 70933 | 114874 | 79558575 |
Logorrhoea | 79.12 | 13.02 | 49 | 70890 | 4316 | 79669133 |
Depressed mood | 78.94 | 13.02 | 149 | 70790 | 48331 | 79625118 |
Fatigue | 78.76 | 13.02 | 495 | 70444 | 929232 | 78744217 |
Parathyroid tumour benign | 78.57 | 13.02 | 29 | 70910 | 790 | 79672659 |
Anxiety | 78.13 | 13.02 | 431 | 70508 | 248081 | 79425368 |
Lethargy | 77.93 | 13.02 | 202 | 70737 | 81090 | 79592359 |
Hypercalcaemia | 77.89 | 13.02 | 130 | 70809 | 38300 | 79635149 |
Pressure of speech | 77.18 | 13.02 | 32 | 70907 | 1196 | 79672253 |
Atrial fibrillation | 76.89 | 13.02 | 40 | 70899 | 197846 | 79475603 |
Mutism | 76.88 | 13.02 | 39 | 70900 | 2333 | 79671116 |
General physical health deterioration | 76.68 | 13.02 | 79 | 70860 | 275159 | 79398290 |
Homicidal ideation | 76.16 | 13.02 | 44 | 70895 | 3413 | 79670036 |
Renal cyst | 76.05 | 13.02 | 79 | 70860 | 14653 | 79658796 |
Drug intolerance | 75.64 | 13.02 | 74 | 70865 | 264045 | 79409404 |
Total lung capacity increased | 75.11 | 13.02 | 38 | 70901 | 2260 | 79671189 |
Coordination abnormal | 73.93 | 13.02 | 84 | 70855 | 17228 | 79656221 |
Hyperprolactinaemia | 73.57 | 13.02 | 48 | 70891 | 4628 | 79668821 |
Choreoathetosis | 72.76 | 13.02 | 33 | 70906 | 1537 | 79671912 |
Glossodynia | 72.42 | 13.02 | 5 | 70934 | 103332 | 79570117 |
Death | 71.65 | 13.02 | 261 | 70678 | 566253 | 79107196 |
Sopor | 71.41 | 13.02 | 115 | 70824 | 32895 | 79640554 |
Contraindicated product administered | 70.44 | 13.02 | 26 | 70913 | 157512 | 79515937 |
Wound | 70.06 | 13.02 | 10 | 70929 | 116169 | 79557280 |
Headache | 69.10 | 13.02 | 323 | 70616 | 653449 | 79020000 |
Enuresis | 68.85 | 13.02 | 40 | 70899 | 3136 | 79670313 |
Affective disorder | 68.84 | 13.02 | 58 | 70881 | 8261 | 79665188 |
Withdrawal syndrome | 68.54 | 13.02 | 101 | 70838 | 26753 | 79646696 |
Intentional product use issue | 68.18 | 13.02 | 25 | 70914 | 152087 | 79521362 |
Chronic kidney disease | 67.16 | 13.02 | 168 | 70771 | 65986 | 79607463 |
Urticaria | 66.83 | 13.02 | 41 | 70898 | 185160 | 79488289 |
Decreased eye contact | 66.30 | 13.02 | 26 | 70913 | 839 | 79672610 |
Hyperparathyroidism primary | 65.93 | 13.02 | 22 | 70917 | 441 | 79673008 |
Thinking abnormal | 65.13 | 13.02 | 69 | 70870 | 13092 | 79660357 |
Drug level above therapeutic | 64.44 | 13.02 | 57 | 70882 | 8666 | 79664783 |
Altered state of consciousness | 64.41 | 13.02 | 129 | 70810 | 43693 | 79629756 |
Abdominal pain upper | 63.74 | 13.02 | 63 | 70876 | 223756 | 79449693 |
Hostility | 63.47 | 13.02 | 34 | 70905 | 2276 | 79671173 |
Aphasia | 63.30 | 13.02 | 133 | 70806 | 46599 | 79626850 |
Asthma-chronic obstructive pulmonary disease overlap syndrome | 63.10 | 13.02 | 38 | 70901 | 3183 | 79670266 |
Disease progression | 62.22 | 13.02 | 44 | 70895 | 184318 | 79489131 |
Body tinea | 61.60 | 13.02 | 31 | 70908 | 1823 | 79671626 |
Poisoning | 61.57 | 13.02 | 93 | 70846 | 25179 | 79648270 |
Increased appetite | 61.42 | 13.02 | 64 | 70875 | 11914 | 79661535 |
Drooling | 61.05 | 13.02 | 47 | 70892 | 5887 | 79667562 |
Camptocormia | 60.90 | 13.02 | 21 | 70918 | 467 | 79672982 |
Blister | 60.05 | 13.02 | 16 | 70923 | 119460 | 79553989 |
Sepsis | 59.74 | 13.02 | 92 | 70847 | 269336 | 79404113 |
Insomnia | 59.73 | 13.02 | 398 | 70541 | 244772 | 79428677 |
Cholelithiasis | 59.08 | 13.02 | 139 | 70800 | 52525 | 79620924 |
Alopecia | 58.32 | 13.02 | 72 | 70867 | 231283 | 79442166 |
Schizoaffective disorder bipolar type | 57.49 | 13.02 | 17 | 70922 | 225 | 79673224 |
Abdominal pain | 56.41 | 13.02 | 169 | 70770 | 389400 | 79284049 |
Poor quality sleep | 55.90 | 13.02 | 84 | 70855 | 22638 | 79650811 |
Somatic symptom disorder | 55.12 | 13.02 | 32 | 70907 | 2505 | 79670944 |
Stupor | 54.99 | 13.02 | 47 | 70892 | 6825 | 79666624 |
Dystonic tremor | 54.73 | 13.02 | 16 | 70923 | 203 | 79673246 |
Disinhibition | 54.41 | 13.02 | 32 | 70907 | 2566 | 79670883 |
Encephalopathy | 54.16 | 13.02 | 157 | 70782 | 67240 | 79606209 |
Impaired healing | 54.14 | 13.02 | 7 | 70932 | 87648 | 79585801 |
Cardiac failure congestive | 53.53 | 13.02 | 30 | 70909 | 142372 | 79531077 |
Anger | 53.42 | 13.02 | 71 | 70868 | 17091 | 79656358 |
Pneumonia | 52.98 | 13.02 | 357 | 70582 | 659889 | 79013560 |
Asthma | 52.92 | 13.02 | 27 | 70912 | 135068 | 79538381 |
Therapeutic product effect decreased | 52.84 | 13.02 | 41 | 70898 | 163822 | 79509627 |
Blood sodium increased | 51.56 | 13.02 | 39 | 70900 | 4759 | 79668690 |
Gastrointestinal haemorrhage | 51.51 | 13.02 | 34 | 70905 | 147685 | 79525764 |
Psoriatic arthropathy | 51.26 | 13.02 | 5 | 70934 | 77994 | 79595455 |
Diarrhoea | 51.16 | 13.02 | 519 | 70420 | 879970 | 78793479 |
Septic shock | 50.46 | 13.02 | 23 | 70916 | 122778 | 79550671 |
Bronchitis | 49.86 | 13.02 | 27 | 70912 | 130617 | 79542832 |
Hepatotoxicity | 49.61 | 13.02 | 128 | 70811 | 51224 | 79622225 |
Anticholinergic syndrome | 49.44 | 13.02 | 34 | 70905 | 3577 | 79669872 |
Cerebellar syndrome | 49.08 | 13.02 | 40 | 70899 | 5440 | 79668009 |
Abulia | 49.05 | 13.02 | 22 | 70917 | 998 | 79672451 |
Distractibility | 48.81 | 13.02 | 20 | 70919 | 725 | 79672724 |
Neurological symptom | 48.79 | 13.02 | 49 | 70890 | 8734 | 79664715 |
Drug reaction with eosinophilia and systemic symptoms | 47.21 | 13.02 | 145 | 70794 | 64099 | 79609350 |
Thrombocytopenia | 46.88 | 13.02 | 104 | 70835 | 265155 | 79408294 |
Ascites | 46.75 | 13.02 | 6 | 70933 | 75556 | 79597893 |
Memory impairment | 46.56 | 13.02 | 210 | 70729 | 111524 | 79561925 |
Resting tremor | 46.37 | 13.02 | 24 | 70915 | 1497 | 79671952 |
Cerebellar atrophy | 46.33 | 13.02 | 22 | 70917 | 1139 | 79672310 |
Abdominal discomfort | 46.23 | 13.02 | 96 | 70843 | 250631 | 79422818 |
Major depression | 46.07 | 13.02 | 48 | 70891 | 8932 | 79664517 |
Electrocardiogram T wave abnormal | 46.07 | 13.02 | 33 | 70906 | 3705 | 79669744 |
Oxygen saturation decreased | 45.95 | 13.02 | 29 | 70910 | 129018 | 79544431 |
Musculoskeletal pain | 45.56 | 13.02 | 17 | 70922 | 102337 | 79571112 |
Fibromyalgia | 45.41 | 13.02 | 3 | 70936 | 64337 | 79609112 |
Electrocardiogram QRS complex prolonged | 45.30 | 13.02 | 52 | 70887 | 10781 | 79662668 |
Inhibitory drug interaction | 45.23 | 13.02 | 35 | 70904 | 4418 | 79669031 |
Seizure | 45.03 | 13.02 | 305 | 70634 | 188529 | 79484920 |
Trismus | 44.99 | 13.02 | 38 | 70901 | 5429 | 79668020 |
Mental impairment | 44.88 | 13.02 | 69 | 70870 | 18967 | 79654482 |
Injection site erythema | 44.29 | 13.02 | 8 | 70931 | 78189 | 79595260 |
Product tampering | 44.19 | 13.02 | 16 | 70923 | 412 | 79673037 |
Gastrointestinal disorder | 44.15 | 13.02 | 27 | 70912 | 122178 | 79551271 |
Renal oncocytoma | 43.99 | 13.02 | 11 | 70928 | 73 | 79673376 |
Action tremor | 43.48 | 13.02 | 16 | 70923 | 432 | 79673017 |
Osteoarthritis | 43.29 | 13.02 | 12 | 70927 | 87297 | 79586152 |
Bradykinesia | 43.09 | 13.02 | 44 | 70895 | 7999 | 79665450 |
Cardio-respiratory arrest | 43.03 | 13.02 | 201 | 70738 | 108309 | 79565140 |
Metabolic syndrome | 42.80 | 13.02 | 28 | 70911 | 2712 | 79670737 |
Malaise | 42.77 | 13.02 | 258 | 70681 | 489611 | 79183838 |
Failure to suspend medication | 42.60 | 13.02 | 16 | 70923 | 458 | 79672991 |
Productive cough | 42.22 | 13.02 | 13 | 70926 | 88318 | 79585131 |
Pericarditis | 42.09 | 13.02 | 20 | 70919 | 104216 | 79569233 |
Adulterated product | 41.99 | 13.02 | 14 | 70925 | 280 | 79673169 |
Blunted affect | 41.86 | 13.02 | 16 | 70923 | 481 | 79672968 |
Blood prolactin increased | 41.77 | 13.02 | 32 | 70907 | 3979 | 79669470 |
Postural tremor | 41.71 | 13.02 | 18 | 70921 | 744 | 79672705 |
Infection susceptibility increased | 41.66 | 13.02 | 31 | 70908 | 3690 | 79669759 |
Depressive symptom | 41.63 | 13.02 | 39 | 70900 | 6384 | 79667065 |
Claustrophobia | 41.51 | 13.02 | 21 | 70918 | 1249 | 79672200 |
Electrocardiogram T wave inversion | 41.48 | 13.02 | 36 | 70903 | 5336 | 79668113 |
Muscle twitching | 41.41 | 13.02 | 77 | 70862 | 24687 | 79648762 |
Mood swings | 41.29 | 13.02 | 68 | 70871 | 19812 | 79653637 |
Personality disorder | 41.15 | 13.02 | 38 | 70901 | 6108 | 79667341 |
Thrombosis | 40.88 | 13.02 | 12 | 70927 | 84088 | 79589361 |
Myocardial infarction | 40.67 | 13.02 | 63 | 70876 | 184066 | 79489383 |
Pancytopenia | 40.28 | 13.02 | 53 | 70886 | 165692 | 79507757 |
Weight decreased | 40.13 | 13.02 | 171 | 70768 | 355027 | 79318422 |
Soft tissue injury | 40.12 | 13.02 | 23 | 70916 | 1758 | 79671691 |
Visuospatial deficit | 39.78 | 13.02 | 9 | 70930 | 36 | 79673413 |
Discomfort | 39.78 | 13.02 | 32 | 70907 | 125585 | 79547864 |
Pneumonitis | 39.74 | 13.02 | 4 | 70935 | 60856 | 79612593 |
Drug hypersensitivity | 39.52 | 13.02 | 135 | 70804 | 298781 | 79374668 |
Haemodialysis | 38.89 | 13.02 | 63 | 70876 | 18105 | 79655344 |
Hallucination | 38.64 | 13.02 | 165 | 70774 | 85580 | 79587869 |
Psychiatric symptom | 38.62 | 13.02 | 39 | 70900 | 6996 | 79666453 |
Decreased appetite | 38.59 | 13.02 | 165 | 70774 | 342253 | 79331196 |
Oculogyric crisis | 38.55 | 13.02 | 27 | 70912 | 2925 | 79670524 |
Behaviour disorder | 38.38 | 13.02 | 37 | 70902 | 6276 | 79667173 |
Chest pain | 38.34 | 13.02 | 126 | 70813 | 282178 | 79391271 |
Erythema | 38.27 | 13.02 | 89 | 70850 | 223201 | 79450248 |
Drug withdrawal syndrome | 38.25 | 13.02 | 91 | 70848 | 34627 | 79638822 |
Persecutory delusion | 38.11 | 13.02 | 33 | 70906 | 4876 | 79668573 |
Psychiatric decompensation | 37.77 | 13.02 | 30 | 70909 | 3933 | 79669516 |
Glucose tolerance impaired | 37.57 | 13.02 | 41 | 70898 | 8043 | 79665406 |
Electroencephalogram abnormal | 37.16 | 13.02 | 34 | 70905 | 5400 | 79668049 |
Hypothermia | 37.13 | 13.02 | 70 | 70869 | 22676 | 79650773 |
Anaphylactic reaction | 37.12 | 13.02 | 14 | 70925 | 83729 | 79589720 |
Hyperthyroidism | 37.07 | 13.02 | 69 | 70870 | 22140 | 79651309 |
Feelings of worthlessness | 36.78 | 13.02 | 15 | 70924 | 537 | 79672912 |
Electroconvulsive therapy | 36.64 | 13.02 | 10 | 70929 | 97 | 79673352 |
Goitre | 36.61 | 13.02 | 34 | 70905 | 5505 | 79667944 |
Lung disorder | 36.50 | 13.02 | 13 | 70926 | 80544 | 79592905 |
Flight of ideas | 36.45 | 13.02 | 17 | 70922 | 845 | 79672604 |
Suspected suicide | 36.42 | 13.02 | 46 | 70893 | 10530 | 79662919 |
Sleep-related eating disorder | 36.26 | 13.02 | 16 | 70923 | 698 | 79672751 |
Cardiac failure | 36.13 | 13.02 | 51 | 70888 | 154791 | 79518658 |
Hypertonia | 35.93 | 13.02 | 38 | 70901 | 7194 | 79666255 |
Asterixis | 35.91 | 13.02 | 25 | 70914 | 2682 | 79670767 |
Self-injurious ideation | 35.66 | 13.02 | 28 | 70911 | 3610 | 79669839 |
Galactorrhoea | 35.60 | 13.02 | 28 | 70911 | 3618 | 79669831 |
Nasal polyps | 35.52 | 13.02 | 38 | 70901 | 7289 | 79666160 |
Hyperthermia | 35.19 | 13.02 | 60 | 70879 | 17977 | 79655472 |
Respiratory arrest | 35.17 | 13.02 | 122 | 70817 | 57428 | 79616021 |
Melaena | 34.98 | 13.02 | 6 | 70933 | 60884 | 79612565 |
Muscle contractions involuntary | 34.81 | 13.02 | 28 | 70911 | 3737 | 79669712 |
Social avoidant behaviour | 34.65 | 13.02 | 31 | 70908 | 4783 | 79668666 |
Epistaxis | 34.57 | 13.02 | 29 | 70910 | 111486 | 79561963 |
Haemorrhage | 34.52 | 13.02 | 19 | 70920 | 91099 | 79582350 |
Impulsive behaviour | 34.36 | 13.02 | 25 | 70914 | 2875 | 79670574 |
Mood altered | 34.34 | 13.02 | 59 | 70880 | 17788 | 79655661 |
Acute psychosis | 34.29 | 13.02 | 29 | 70910 | 4151 | 79669298 |
Blood bilirubin increased | 34.25 | 13.02 | 133 | 70806 | 66099 | 79607350 |
Post-traumatic neck syndrome | 34.18 | 13.02 | 22 | 70917 | 2072 | 79671377 |
Blood thyroid stimulating hormone decreased | 33.81 | 13.02 | 33 | 70906 | 5683 | 79667766 |
Blood pressure fluctuation | 33.72 | 13.02 | 9 | 70930 | 67136 | 79606313 |
Plasma cell myeloma | 33.50 | 13.02 | 4 | 70935 | 53255 | 79620194 |
Hyperkinesia | 33.42 | 13.02 | 24 | 70915 | 2705 | 79670744 |
Feeling guilty | 33.27 | 13.02 | 16 | 70923 | 852 | 79672597 |
Sarcoidosis | 33.17 | 13.02 | 39 | 70900 | 8296 | 79665153 |
Electrocardiogram abnormal | 33.09 | 13.02 | 56 | 70883 | 16681 | 79656768 |
Bradyphrenia | 33.08 | 13.02 | 44 | 70895 | 10596 | 79662853 |
International normalised ratio increased | 33.08 | 13.02 | 17 | 70922 | 84704 | 79588745 |
Lower respiratory tract infection | 32.77 | 13.02 | 40 | 70899 | 129180 | 79544269 |
Nodal rhythm | 32.62 | 13.02 | 25 | 70914 | 3110 | 79670339 |
Therapeutic product effect variable | 32.53 | 13.02 | 21 | 70918 | 1988 | 79671461 |
Dysphemia | 32.40 | 13.02 | 26 | 70913 | 3458 | 79669991 |
Injection site pain | 32.08 | 13.02 | 41 | 70898 | 129797 | 79543652 |
Speech sound disorder | 32.00 | 13.02 | 8 | 70931 | 53 | 79673396 |
Gait disturbance | 31.85 | 13.02 | 303 | 70636 | 207203 | 79466246 |
Mobility decreased | 31.85 | 13.02 | 37 | 70902 | 122138 | 79551311 |
Pleural effusion | 31.79 | 13.02 | 50 | 70889 | 145212 | 79528237 |
Dyspnoea exertional | 31.78 | 13.02 | 19 | 70920 | 87054 | 79586395 |
Rhinalgia | 31.73 | 13.02 | 22 | 70917 | 2345 | 79671104 |
Autonomic nervous system imbalance | 31.72 | 13.02 | 29 | 70910 | 4601 | 79668848 |
Rhinorrhoea | 31.64 | 13.02 | 14 | 70925 | 76060 | 79597389 |
Oncocytoma | 31.14 | 13.02 | 7 | 70932 | 27 | 79673422 |
Echolalia | 31.11 | 13.02 | 12 | 70927 | 370 | 79673079 |
Antipsychotic drug level decreased | 30.81 | 13.02 | 17 | 70922 | 1207 | 79672242 |
Inflammation | 30.80 | 13.02 | 23 | 70916 | 93730 | 79579719 |
Cerebrovascular accident | 30.73 | 13.02 | 57 | 70882 | 155235 | 79518214 |
Agranulocytosis | 30.66 | 13.02 | 99 | 70840 | 44931 | 79628518 |
Amenorrhoea | 30.62 | 13.02 | 36 | 70903 | 7656 | 79665793 |
Restless legs syndrome | 30.55 | 13.02 | 60 | 70879 | 20032 | 79653417 |
Sternal fracture | 30.41 | 13.02 | 22 | 70917 | 2508 | 79670941 |
Papillary thyroid cancer | 29.98 | 13.02 | 22 | 70917 | 2564 | 79670885 |
Influenza | 29.92 | 13.02 | 43 | 70896 | 129563 | 79543886 |
Judgement impaired | 29.85 | 13.02 | 17 | 70922 | 1283 | 79672166 |
Urinary incontinence | 29.74 | 13.02 | 92 | 70847 | 40817 | 79632632 |
Neutrophilia | 29.66 | 13.02 | 36 | 70903 | 7915 | 79665534 |
Product use issue | 29.63 | 13.02 | 92 | 70847 | 209730 | 79463719 |
Haemoglobin decreased | 29.56 | 13.02 | 100 | 70839 | 222019 | 79451430 |
Tachycardia | 29.51 | 13.02 | 264 | 70675 | 177504 | 79495945 |
Blood creatinine increased | 29.29 | 13.02 | 237 | 70702 | 154820 | 79518629 |
Acute myocardial infarction | 29.27 | 13.02 | 16 | 70923 | 77020 | 79596429 |
Dysphoria | 29.26 | 13.02 | 28 | 70911 | 4706 | 79668743 |
Convulsive threshold lowered | 29.04 | 13.02 | 15 | 70924 | 932 | 79672517 |
Hyperhidrosis | 28.86 | 13.02 | 232 | 70707 | 151260 | 79522189 |
Cardiac hypertrophy | 28.79 | 13.02 | 18 | 70921 | 1612 | 79671837 |
Adams-Stokes syndrome | 28.63 | 13.02 | 9 | 70930 | 148 | 79673301 |
Otospondylomegaepiphyseal dysplasia | 28.60 | 13.02 | 7 | 70932 | 42 | 79673407 |
Hypokalaemia | 28.39 | 13.02 | 53 | 70886 | 143987 | 79529462 |
Pyrexia | 28.38 | 13.02 | 429 | 70510 | 678280 | 78995169 |
Bundle branch block right | 28.25 | 13.02 | 42 | 70897 | 11209 | 79662240 |
Rebound psychosis | 27.82 | 13.02 | 11 | 70928 | 363 | 79673086 |
Patient restraint | 27.70 | 13.02 | 8 | 70931 | 97 | 79673352 |
Treatment failure | 27.59 | 13.02 | 70 | 70869 | 170416 | 79503033 |
Lymphocyte count abnormal | 27.57 | 13.02 | 17 | 70922 | 1486 | 79671963 |
Long QT syndrome | 27.32 | 13.02 | 30 | 70909 | 5925 | 79667524 |
Tachyphrenia | 27.11 | 13.02 | 19 | 70920 | 2061 | 79671388 |
Hallucination, visual | 27.02 | 13.02 | 77 | 70862 | 32652 | 79640797 |
Bone pain | 27.01 | 13.02 | 8 | 70931 | 55734 | 79617715 |
Upper respiratory tract infection | 26.70 | 13.02 | 25 | 70914 | 91143 | 79582306 |
Upper gastrointestinal haemorrhage | 26.30 | 13.02 | 3 | 70936 | 41377 | 79632072 |
Parkinsonian gait | 26.18 | 13.02 | 14 | 70925 | 934 | 79672515 |
Wrong patient received product | 26.09 | 13.02 | 26 | 70913 | 4592 | 79668857 |
Hereditary ataxia | 25.95 | 13.02 | 6 | 70933 | 27 | 79673422 |
Paraesthesia | 25.83 | 13.02 | 76 | 70863 | 176247 | 79497202 |
Skin ulcer | 25.82 | 13.02 | 8 | 70931 | 54142 | 79619307 |
Acquired cystic kidney disease | 25.73 | 13.02 | 7 | 70932 | 67 | 79673382 |
Hyporeflexia | 25.73 | 13.02 | 23 | 70916 | 3545 | 79669904 |
Knee arthroplasty | 25.43 | 13.02 | 4 | 70935 | 43244 | 79630205 |
Myelosuppression | 25.41 | 13.02 | 3 | 70936 | 40293 | 79633156 |
Osteonecrosis of jaw | 25.41 | 13.02 | 4 | 70935 | 43222 | 79630227 |
Acute kidney injury | 25.13 | 13.02 | 622 | 70317 | 518782 | 79154667 |
Diabetic coma | 25.13 | 13.02 | 15 | 70924 | 1236 | 79672213 |
Flat affect | 25.11 | 13.02 | 18 | 70921 | 2023 | 79671426 |
Cerebral haemorrhage | 24.97 | 13.02 | 10 | 70929 | 57663 | 79615786 |
Gaze palsy | 24.96 | 13.02 | 21 | 70918 | 2984 | 79670465 |
Cystitis | 24.77 | 13.02 | 8 | 70931 | 52724 | 79620725 |
Delusion of reference | 24.68 | 13.02 | 8 | 70931 | 146 | 79673303 |
Substance abuse | 24.60 | 13.02 | 38 | 70901 | 10488 | 79662961 |
Haematochezia | 24.55 | 13.02 | 25 | 70914 | 87620 | 79585829 |
Defect conduction intraventricular | 24.46 | 13.02 | 11 | 70928 | 502 | 79672947 |
Haematoma | 24.37 | 13.02 | 8 | 70931 | 52187 | 79621262 |
Coronary artery disease | 24.30 | 13.02 | 14 | 70925 | 65460 | 79607989 |
Injection site swelling | 24.27 | 13.02 | 6 | 70933 | 47126 | 79626323 |
Nephropathy toxic | 24.11 | 13.02 | 55 | 70884 | 20364 | 79653085 |
Ideas of reference | 23.90 | 13.02 | 8 | 70931 | 162 | 79673287 |
Staphylococcal infection | 23.81 | 13.02 | 11 | 70928 | 58284 | 79615165 |
Haemoptysis | 23.77 | 13.02 | 10 | 70929 | 55989 | 79617460 |
Chest discomfort | 23.66 | 13.02 | 55 | 70884 | 137989 | 79535460 |
Neuropathy peripheral | 23.66 | 13.02 | 57 | 70882 | 141248 | 79532201 |
Coma | 23.63 | 13.02 | 162 | 70777 | 100487 | 79572962 |
Rhabdomyolysis | 23.63 | 13.02 | 165 | 70774 | 102966 | 79570483 |
Hyperammonaemic encephalopathy | 23.53 | 13.02 | 25 | 70914 | 4757 | 79668692 |
Nystagmus | 23.49 | 13.02 | 36 | 70903 | 9868 | 79663581 |
Sinus arrest | 23.49 | 13.02 | 22 | 70917 | 3600 | 79669849 |
Muscle injury | 23.47 | 13.02 | 7 | 70932 | 48554 | 79624895 |
Sluggishness | 23.29 | 13.02 | 29 | 70910 | 6543 | 79666906 |
Antipsychotic drug level | 23.21 | 13.02 | 5 | 70934 | 15 | 79673434 |
Balance disorder | 23.14 | 13.02 | 159 | 70780 | 98698 | 79574751 |
Hyperammonaemia | 23.11 | 13.02 | 38 | 70901 | 11055 | 79662394 |
Rhinitis allergic | 22.87 | 13.02 | 40 | 70899 | 12229 | 79661220 |
Metabolic encephalopathy | 22.76 | 13.02 | 34 | 70905 | 9113 | 79664336 |
Hyperkalaemia | 22.62 | 13.02 | 42 | 70897 | 114356 | 79559093 |
Blood pressure systolic increased | 22.57 | 13.02 | 16 | 70923 | 66970 | 79606479 |
Antidepressant drug level increased | 22.54 | 13.02 | 10 | 70929 | 442 | 79673007 |
Thyroiditis | 22.53 | 13.02 | 24 | 70915 | 4581 | 79668868 |
Sexual dysfunction | 22.46 | 13.02 | 31 | 70908 | 7732 | 79665717 |
Angina pectoris | 22.34 | 13.02 | 9 | 70930 | 51723 | 79621726 |
Muscle spasms | 22.34 | 13.02 | 80 | 70859 | 174650 | 79498799 |
Hypoxia | 22.15 | 13.02 | 36 | 70903 | 103207 | 79570242 |
Oromandibular dystonia | 22.08 | 13.02 | 13 | 70926 | 1045 | 79672404 |
Obesity | 21.93 | 13.02 | 75 | 70864 | 35050 | 79638399 |
Dry skin | 21.92 | 13.02 | 17 | 70922 | 67978 | 79605471 |
Drug level decreased | 21.88 | 13.02 | 43 | 70896 | 14359 | 79659090 |
Hallucination, olfactory | 21.81 | 13.02 | 10 | 70929 | 478 | 79672971 |
Eosinophilia | 21.78 | 13.02 | 89 | 70850 | 45256 | 79628193 |
Negativism | 21.76 | 13.02 | 12 | 70927 | 851 | 79672598 |
Status epilepticus | 21.74 | 13.02 | 60 | 70879 | 24981 | 79648468 |
Colitis | 21.59 | 13.02 | 20 | 70919 | 73287 | 79600162 |
Ileus paralytic | 21.47 | 13.02 | 34 | 70905 | 9586 | 79663863 |
Clear cell renal cell carcinoma | 21.39 | 13.02 | 18 | 70921 | 2558 | 79670891 |
Maternal exposure during pregnancy | 21.37 | 13.02 | 57 | 70882 | 136481 | 79536968 |
High-grade B-cell lymphoma | 21.23 | 13.02 | 7 | 70932 | 135 | 79673314 |
Thought blocking | 21.20 | 13.02 | 8 | 70931 | 232 | 79673217 |
Consciousness fluctuating | 21.15 | 13.02 | 16 | 70923 | 1953 | 79671496 |
Rectal haemorrhage | 21.10 | 13.02 | 22 | 70917 | 76278 | 79597171 |
CSWS syndrome | 21.03 | 13.02 | 5 | 70934 | 26 | 79673423 |
Hepatocellular injury | 21.02 | 13.02 | 8 | 70931 | 47585 | 79625864 |
Localised infection | 20.94 | 13.02 | 4 | 70935 | 37571 | 79635878 |
Muscle contracture | 20.93 | 13.02 | 17 | 70922 | 2300 | 79671149 |
Ear infection | 20.67 | 13.02 | 3 | 70936 | 34429 | 79639020 |
Fluid retention | 20.61 | 13.02 | 19 | 70920 | 69790 | 79603659 |
Unmasking of previously unidentified disease | 20.53 | 13.02 | 16 | 70923 | 2041 | 79671408 |
Lactate pyruvate ratio increased | 20.32 | 13.02 | 6 | 70933 | 79 | 79673370 |
Mydriasis | 20.25 | 13.02 | 47 | 70892 | 17596 | 79655853 |
Cardiac murmur | 20.23 | 13.02 | 44 | 70895 | 15780 | 79657669 |
Cerebral atrophy | 20.07 | 13.02 | 30 | 70909 | 8045 | 79665404 |
Oropharyngeal pain | 20.02 | 13.02 | 42 | 70897 | 109311 | 79564138 |
Diverticulitis | 19.83 | 13.02 | 8 | 70931 | 45928 | 79627521 |
Thyrotoxic crisis | 19.76 | 13.02 | 13 | 70926 | 1271 | 79672178 |
Injection site bruising | 19.65 | 13.02 | 6 | 70933 | 40996 | 79632453 |
Off label use | 19.53 | 13.02 | 637 | 70302 | 906578 | 78766871 |
Irritable bowel syndrome | 19.52 | 13.02 | 16 | 70923 | 62225 | 79611224 |
Drug abuse | 19.50 | 13.02 | 226 | 70713 | 162465 | 79510984 |
Brain injury | 19.49 | 13.02 | 36 | 70903 | 11481 | 79661968 |
Ill-defined disorder | 19.37 | 13.02 | 18 | 70921 | 65857 | 79607592 |
Full blood count abnormal | 19.26 | 13.02 | 6 | 70933 | 40468 | 79632981 |
Conduction disorder | 19.04 | 13.02 | 19 | 70920 | 3360 | 79670089 |
Staring | 18.97 | 13.02 | 17 | 70922 | 2628 | 79670821 |
Eosinophil count decreased | 18.96 | 13.02 | 19 | 70920 | 3377 | 79670072 |
Myoclonic epilepsy | 18.96 | 13.02 | 15 | 70924 | 1955 | 79671494 |
Blood triglycerides increased | 18.85 | 13.02 | 51 | 70888 | 20989 | 79652460 |
Basal cell carcinoma | 18.78 | 13.02 | 5 | 70934 | 37370 | 79636079 |
Colitis ulcerative | 18.73 | 13.02 | 4 | 70935 | 34738 | 79638711 |
Sinus bradycardia | 18.56 | 13.02 | 57 | 70882 | 25190 | 79648259 |
Blood thyroid stimulating hormone increased | 18.55 | 13.02 | 32 | 70907 | 9676 | 79663773 |
Nausea | 18.55 | 13.02 | 681 | 70258 | 956515 | 78716934 |
Fungal infection | 18.46 | 13.02 | 7 | 70932 | 41741 | 79631708 |
Torticollis | 18.44 | 13.02 | 16 | 70923 | 2371 | 79671078 |
Sleep disorder | 18.42 | 13.02 | 135 | 70804 | 85542 | 79587907 |
Histrionic personality disorder | 18.37 | 13.02 | 5 | 70934 | 48 | 79673401 |
Differential white blood cell count abnormal | 18.26 | 13.02 | 15 | 70924 | 2062 | 79671387 |
Osteonecrosis | 18.00 | 13.02 | 3 | 70936 | 31092 | 79642357 |
Hypophagia | 17.95 | 13.02 | 84 | 70855 | 45283 | 79628166 |
Femur fracture | 17.92 | 13.02 | 6 | 70933 | 38646 | 79634803 |
Throat irritation | 17.89 | 13.02 | 7 | 70932 | 40939 | 79632510 |
Secondary tic | 17.88 | 13.02 | 4 | 70935 | 15 | 79673434 |
Intention tremor | 17.79 | 13.02 | 10 | 70929 | 736 | 79672713 |
Sexually inappropriate behaviour | 17.78 | 13.02 | 9 | 70930 | 536 | 79672913 |
Angioedema | 17.77 | 13.02 | 25 | 70914 | 76010 | 79597439 |
Hallucinations, mixed | 17.68 | 13.02 | 26 | 70913 | 6873 | 79666576 |
Decreased interest | 17.62 | 13.02 | 19 | 70920 | 3678 | 79669771 |
Prostate cancer | 17.59 | 13.02 | 4 | 70935 | 33264 | 79640185 |
Blood citric acid increased | 17.43 | 13.02 | 5 | 70934 | 59 | 79673390 |
Social anxiety disorder | 17.38 | 13.02 | 9 | 70930 | 562 | 79672887 |
Bacteraemia | 17.25 | 13.02 | 4 | 70935 | 32820 | 79640629 |
Pulse abnormal | 17.20 | 13.02 | 18 | 70921 | 3366 | 79670083 |
COVID-19 | 17.11 | 13.02 | 77 | 70862 | 157597 | 79515852 |
Myalgia | 17.10 | 13.02 | 96 | 70843 | 185545 | 79487904 |
Body mass index increased | 17.08 | 13.02 | 14 | 70925 | 1919 | 79671530 |
Merycism | 17.00 | 13.02 | 7 | 70932 | 257 | 79673192 |
Incoherent | 16.91 | 13.02 | 27 | 70912 | 7665 | 79665784 |
Sinus node dysfunction | 16.88 | 13.02 | 27 | 70912 | 7674 | 79665775 |
Movement disorder | 16.84 | 13.02 | 58 | 70881 | 27201 | 79646248 |
Night sweats | 16.83 | 13.02 | 13 | 70926 | 52082 | 79621367 |
Haematuria | 16.73 | 13.02 | 22 | 70917 | 68814 | 79604635 |
Dry eye | 16.66 | 13.02 | 6 | 70933 | 36925 | 79636524 |
Bradycardia | 16.55 | 13.02 | 189 | 70750 | 135368 | 79538081 |
Gestational diabetes | 16.54 | 13.02 | 24 | 70915 | 6269 | 79667180 |
Gambling disorder | 16.50 | 13.02 | 14 | 70925 | 2012 | 79671437 |
Activation syndrome | 16.48 | 13.02 | 7 | 70932 | 278 | 79673171 |
Concussion | 16.46 | 13.02 | 30 | 70909 | 9473 | 79663976 |
Bipolar II disorder | 16.34 | 13.02 | 8 | 70931 | 443 | 79673006 |
Nephrolithiasis | 16.34 | 13.02 | 14 | 70925 | 53277 | 79620172 |
Limbic encephalitis | 16.31 | 13.02 | 10 | 70929 | 865 | 79672584 |
Sleep apnoea syndrome | 16.28 | 13.02 | 70 | 70869 | 36408 | 79637041 |
Atrioventricular block first degree | 16.27 | 13.02 | 35 | 70904 | 12456 | 79660993 |
Oedema peripheral | 16.13 | 13.02 | 145 | 70794 | 252143 | 79421306 |
Mouth ulceration | 16.07 | 13.02 | 7 | 70932 | 38387 | 79635062 |
Antidepressant drug level above therapeutic | 15.95 | 13.02 | 9 | 70930 | 667 | 79672782 |
Metabolic disorder | 15.94 | 13.02 | 29 | 70910 | 9141 | 79664308 |
Dyslipidaemia | 15.62 | 13.02 | 33 | 70906 | 11600 | 79661849 |
Pain in jaw | 15.57 | 13.02 | 11 | 70928 | 46140 | 79627309 |
Blood pressure increased | 15.55 | 13.02 | 117 | 70822 | 211243 | 79462206 |
Autoimmune thyroiditis | 15.52 | 13.02 | 19 | 70920 | 4214 | 79669235 |
Injection site haemorrhage | 15.46 | 13.02 | 3 | 70936 | 27867 | 79645582 |
Hepatic failure | 15.46 | 13.02 | 19 | 70920 | 61193 | 79612256 |
Tic | 15.39 | 13.02 | 16 | 70923 | 2970 | 79670479 |
Neoplasm progression | 15.34 | 13.02 | 14 | 70925 | 51668 | 79621781 |
Essential tremor | 15.31 | 13.02 | 12 | 70927 | 1543 | 79671906 |
Urine output increased | 15.20 | 13.02 | 14 | 70925 | 2242 | 79671207 |
Cerebral amyloid angiopathy | 15.16 | 13.02 | 7 | 70932 | 340 | 79673109 |
Cerebellar ataxia | 15.09 | 13.02 | 13 | 70926 | 1908 | 79671541 |
Refusal of treatment by patient | 15.09 | 13.02 | 28 | 70911 | 8963 | 79664486 |
Oscillopsia | 15.06 | 13.02 | 6 | 70933 | 202 | 79673247 |
Generalised tonic-clonic seizure | 15.02 | 13.02 | 78 | 70861 | 43832 | 79629617 |
Impaired work ability | 14.99 | 13.02 | 45 | 70894 | 19636 | 79653813 |
Water intoxication | 14.82 | 13.02 | 9 | 70930 | 765 | 79672684 |
Cyclothymic disorder | 14.79 | 13.02 | 6 | 70933 | 212 | 79673237 |
Eye movement disorder | 14.78 | 13.02 | 26 | 70913 | 7985 | 79665464 |
Device related infection | 14.75 | 13.02 | 6 | 70933 | 34288 | 79639161 |
Thyroid function test abnormal | 14.75 | 13.02 | 16 | 70923 | 3118 | 79670331 |
Parasomnia | 14.70 | 13.02 | 8 | 70931 | 553 | 79672896 |
Platelet count decreased | 14.69 | 13.02 | 107 | 70832 | 194557 | 79478892 |
Glomerulonephritis minimal lesion | 14.68 | 13.02 | 9 | 70930 | 778 | 79672671 |
Flatulence | 14.66 | 13.02 | 10 | 70929 | 42714 | 79630735 |
Clostridium difficile infection | 14.64 | 13.02 | 10 | 70929 | 42675 | 79630774 |
Diabetic hyperosmolar coma | 14.58 | 13.02 | 9 | 70930 | 788 | 79672661 |
Human herpesvirus 6 infection reactivation | 14.51 | 13.02 | 8 | 70931 | 567 | 79672882 |
Hypersexuality | 14.49 | 13.02 | 12 | 70927 | 1668 | 79671781 |
Obstructive airways disorder | 14.38 | 13.02 | 5 | 70934 | 31454 | 79641995 |
Pulmonary mass | 14.37 | 13.02 | 4 | 70935 | 29030 | 79644419 |
Suicidal behaviour | 14.28 | 13.02 | 16 | 70923 | 3231 | 79670218 |
Bursitis | 14.28 | 13.02 | 7 | 70932 | 35837 | 79637612 |
Polyhydramnios | 14.25 | 13.02 | 12 | 70927 | 1708 | 79671741 |
Apraxia | 14.13 | 13.02 | 15 | 70924 | 2852 | 79670597 |
Hypovolaemia | 14 | 13.02 | 41 | 70898 | 17650 | 79655799 |
Acute myeloid leukaemia | 13.96 | 13.02 | 5 | 70934 | 30880 | 79642569 |
Toxic cardiomyopathy | 13.95 | 13.02 | 7 | 70932 | 409 | 79673040 |
Dysphagia | 13.90 | 13.02 | 168 | 70771 | 121968 | 79551481 |
Hip fracture | 13.87 | 13.02 | 5 | 70934 | 30756 | 79642693 |
Dialysis | 13.86 | 13.02 | 42 | 70897 | 18420 | 79655029 |
Accidental death | 13.73 | 13.02 | 18 | 70921 | 4273 | 79669176 |
Fluid intake reduced | 13.72 | 13.02 | 22 | 70917 | 6266 | 79667183 |
Toxic encephalopathy | 13.71 | 13.02 | 31 | 70908 | 11409 | 79662040 |
Posture abnormal | 13.61 | 13.02 | 17 | 70922 | 3849 | 79669600 |
Persistent depressive disorder | 13.40 | 13.02 | 10 | 70929 | 1195 | 79672254 |
Ulcer | 13.30 | 13.02 | 5 | 70934 | 29967 | 79643482 |
Waxy flexibility | 13.28 | 13.02 | 6 | 70933 | 277 | 79673172 |
Amimia | 13.19 | 13.02 | 4 | 70935 | 58 | 79673391 |
Stereotypy | 13.18 | 13.02 | 9 | 70930 | 936 | 79672513 |
Tubulointerstitial nephritis | 13.13 | 13.02 | 68 | 70871 | 38167 | 79635282 |
Psychotic disorder due to a general medical condition | 13.12 | 13.02 | 6 | 70933 | 285 | 79673164 |
Psychotic symptom | 13.10 | 13.02 | 14 | 70925 | 2683 | 79670766 |
Mucosal dryness | 13.09 | 13.02 | 16 | 70923 | 3543 | 79669906 |
Small intestinal obstruction | 13.05 | 13.02 | 4 | 70935 | 27268 | 79646181 |
Impaired self-care | 13.05 | 13.02 | 14 | 70925 | 2693 | 79670756 |
Candida infection | 13.04 | 13.02 | 9 | 70930 | 38205 | 79635244 |
None
Source | Code | Description |
---|---|---|
ATC | N05AN01 | NERVOUS SYSTEM PSYCHOLEPTICS ANTIPSYCHOTICS Lithium |
CHEBI has role | CHEBI:35469 | antidepressants |
MeSH PA | D000928 | Antidepressive Agents |
MeSH PA | D018692 | Antimanic Agents |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D011619 | Psychotropic Drugs |
MeSH PA | D014149 | Tranquilizing Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Bipolar disorder | indication | 13746004 | DOID:3312 |
Bipolar disorder in remission | indication | 85248005 | |
Bipolar affective disorder, current episode manic | indication | 191618007 | |
Vascular headache | off-label use | 128187005 | |
Bipolar affective disorder, current episode depression | off-label use | 191627008 | DOID:3312 |
Cluster Headache Prevention | off-label use | ||
Rapid Cycling Bipolar Affective Disorder | off-label use | ||
Psoriasis | contraindication | 9014002 | DOID:8893 |
Diabetes insipidus | contraindication | 15771004 | DOID:9409 |
Polyuria | contraindication | 28442001 | |
Hypothyroidism | contraindication | 40930008 | DOID:1459 |
Conduction disorder of the heart | contraindication | 44808001 | |
Chronic heart failure | contraindication | 48447003 | |
Acute infectious disease | contraindication | 63171007 | |
Hyponatremia | contraindication | 89627008 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Organic mental disorder | contraindication | 111479008 | |
Plaque psoriasis | contraindication | 200965009 | |
Pregnancy, function | contraindication | 289908002 | |
Breastfeeding (mother) | contraindication | 413712001 | |
Severe dehydration | contraindication | 450316000 | |
Lithium Toxicity | contraindication |
None
None
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 | Kinase | INHIBITOR | CHEMBL | CHEMBL | |||||
Inositol-1(or 4)-monophosphatase 1 | Enzyme | INHIBITOR | CHEMBL | CHEMBL |
ID | Source |
---|---|
D04749 | KEGG_DRUG |
4018009 | VUID |
N0000179333 | NUI |
4018008 | VANDF |
4018009 | VANDF |
4019803 | VANDF |
CHEBI:64735 | CHEBI |
CHEBI:30145 | CHEBI |
CHEMBL1201170 | ChEMBL_ID |
CHEMBL2103738 | ChEMBL_ID |
CHEMBL1200826 | ChEMBL_ID |
C070669 | MESH_SUPPLEMENTAL_RECORD_UI |
DB14507 | DRUGBANK_ID |
5Z6E9K79YV | UNII |
DB14509 | DRUGBANK_ID |
203056 | RXNORM |
1994 | MMSL |
2001 | MMSL |
4987 | MMSL |
d00061 | MMSL |
001532 | NDDF |
001534 | NDDF |
17805003 | SNOMEDCT_US |
321719003 | SNOMEDCT_US |
387098001 | SNOMEDCT_US |
85899009 | SNOMEDCT_US |
C0125997 | UMLSCUI |
D016651 | MESH_DESCRIPTOR_UI |
C0023870 | UMLSCUI |
CHEMBL2146126 | ChEMBL_ID |
13520 | PUBCHEM_CID |
6080-58-6 | SECONDARY_CAS_RN |
7439-93-2 | SECONDARY_CAS_RN |
3028194 | PUBCHEM_CID |
D008094 | MESH_DESCRIPTOR_UI |
9FN79X2M3F | UNII |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Lithium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0054-3527 | SOLUTION | 8 meq | ORAL | NDA | 26 sections |
Lithium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0054-3527 | SOLUTION | 8 meq | ORAL | NDA | 26 sections |
Lithium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0054-3527 | SOLUTION | 8 meq | ORAL | NDA | 26 sections |
Lithium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68094-757 | SOLUTION | 8 meq | ORAL | NDA | 27 sections |
Lithium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72888-172 | SOLUTION | 8 meq | ORAL | ANDA | 26 sections |