lithium citrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4512	919-16-4

Description:

Molecule	Description
Synonyms: lithium citrate trilithium citrate lithonate lithium citrate hydrate	Molecular weight: 209.92 Formula: C6H5Li3O7 CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 140.62 ALOGS: ROTB: None

Molecule

Description

Synonyms:

lithium citrate
trilithium citrate
lithonate
lithium citrate hydrate

Molecular weight: 209.92
Formula: C6H5Li3O7
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA: 140.62
ALOGS:
ROTB: None

Drug dosage:

Dose	Unit	Route
24	mmol	O

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Dec. 23, 1980	FDA	ROXANE

FDA Adverse Event Reporting System (Female)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Toxicity to various agents	1391.65	13.37	1279	46226	245971	63195546
Nephrogenic diabetes insipidus	684.53	13.37	156	47349	803	63440714
Tremor	668.15	13.37	646	46859	131593	63309924
Neuroleptic malignant syndrome	643.85	13.37	266	47239	11790	63429727
Mania	560.97	13.37	243	47262	12124	63429393
Drug interaction	473.43	13.37	710	46795	228421	63213096
Hypomania	461.71	13.37	175	47330	6155	63435362
Psychotic disorder	429.02	13.37	257	47248	25455	63416062
Schizophrenia	382.07	13.37	174	47331	9778	63431739
Antipsychotic drug level increased	371.06	13.37	127	47378	3308	63438209

Showing 1 to 10 of 432 entries

Previous1 2 3 4 5…44Next

FDA Adverse Event Reporting System (Male)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Toxicity to various agents	907.15	14.34	1088	36183	199274	34720386
Neuroleptic malignant syndrome	610.44	14.34	323	36948	17611	34902049
Mania	505.01	14.34	232	37039	9279	34910381
Nephrogenic diabetes insipidus	464.42	14.34	131	37140	1190	34918470
Tremor	437.85	14.34	488	36783	82099	34837561
Antipsychotic drug level increased	365.02	14.34	142	37129	3723	34915937
Akathisia	327.59	14.34	164	37107	7945	34911715
Suicide attempt	276.71	14.34	270	37001	38846	34880814
Obsessive-compulsive disorder	271.30	14.34	128	37143	5436	34914224
Extrapyramidal disorder	261.75	14.34	166	37105	12714	34906946

Showing 1 to 10 of 285 entries

Previous1 2 3 4 5…29Next

FDA Adverse Event Reporting System (Geriatric)

Show entries

Search:

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Toxicity to various agents	2032.27	13.02	2167	68772	419373	79254076
Neuroleptic malignant syndrome	1128.39	13.02	531	70408	27028	79646421
Nephrogenic diabetes insipidus	1056.05	13.02	267	70672	1867	79671582
Tremor	1007.08	13.02	980	69959	169103	79504346
Mania	828.81	13.02	378	70561	17882	79655567
Drug interaction	666.16	13.02	1264	69675	413919	79259530
Antipsychotic drug level increased	631.57	13.02	227	70712	5730	79667719
Psychotic disorder	579.90	13.02	395	70544	41007	79632442
Hypomania	568.81	13.02	224	70715	7320	79666129
Extrapyramidal disorder	563.21	13.02	312	70627	22367	79651082

Showing 1 to 10 of 540 entries

Previous1 2 3 4 5…54Next

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Show entries

Search:

Source	Code	Description
ATC	N05AN01	NERVOUS SYSTEM PSYCHOLEPTICS ANTIPSYCHOTICS Lithium
CHEBI has role	CHEBI:35469	antidepressants
MeSH PA	D000928	Antidepressive Agents
MeSH PA	D018692	Antimanic Agents
MeSH PA	D002491	Central Nervous System Agents
MeSH PA	D002492	Central Nervous System Depressants
MeSH PA	D004791	Enzyme Inhibitors
MeSH PA	D011619	Psychotropic Drugs
MeSH PA	D014149	Tranquilizing Agents

Showing 1 to 9 of 9 entries

Previous1Next

Drug Use | Suggest Off label Use Form| |View source of the data|

Show entries

Search:

Disease	Relation	SNOMED_ID	DOID
Bipolar disorder	indication	13746004	DOID:3312
Bipolar disorder in remission	indication	85248005
Bipolar affective disorder, current episode manic	indication	191618007
Vascular headache	off-label use	128187005
Bipolar affective disorder, current episode depression	off-label use	191627008	DOID:3312
Cluster Headache Prevention	off-label use
Rapid Cycling Bipolar Affective Disorder	off-label use
Psoriasis	contraindication	9014002	DOID:8893
Diabetes insipidus	contraindication	15771004	DOID:9409
Polyuria	contraindication	28442001

Showing 1 to 10 of 22 entries

Previous1 2 3Next

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Show entries

Search:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Glycogen synthase kinase-3	Kinase	P49840 P49841	GSK3A_HUMAN GSK3B_HUMAN	INHIBITOR				CHEMBL	CHEMBL
Inositol-1(or 4)-monophosphatase 1	Enzyme	P29218	IMPA1_HUMAN	INHIBITOR				CHEMBL	CHEMBL

Showing 1 to 2 of 2 entries

Previous1Next

External reference:

Show entries

Search:

ID	Source
001532	NDDF
001534	NDDF
13520	PUBCHEM_CID
17805003	SNOMEDCT_US
1994	MMSL
2001	MMSL
203056	RXNORM
3028194	PUBCHEM_CID
321719003	SNOMEDCT_US
387098001	SNOMEDCT_US

Showing 1 to 10 of 36 entries

Previous1 2 3 4Next

Pharmaceutical products:

Show entries

Search:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Lithium	HUMAN PRESCRIPTION DRUG LABEL	1	0054-3527	SOLUTION	8 meq	ORAL	NDA	26 sections
Lithium	HUMAN PRESCRIPTION DRUG LABEL	1	0054-3527	SOLUTION	8 meq	ORAL	NDA	26 sections
Lithium	HUMAN PRESCRIPTION DRUG LABEL	1	0054-3527	SOLUTION	8 meq	ORAL	NDA	26 sections
Lithium	HUMAN PRESCRIPTION DRUG LABEL	1	68094-757	SOLUTION	8 meq	ORAL	NDA	27 sections
Lithium	HUMAN PRESCRIPTION DRUG LABEL	1	72888-172	SOLUTION	8 meq	ORAL	ANDA	26 sections

Showing 1 to 5 of 5 entries

Previous1Next