magnesium salicylate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4510 18917-89-0

Description:

MoleculeDescription

Synonyms:

  • magnesium salicylate tetrahydrate
  • magnesium salicylate hydrate
  • magan
  • magnesium salicylate
  • Molecular weight: 298.53
  • Formula: C14H10MgO6
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Broncholithiasis 76.98 34.27 10 414 243 63488355
Lymph node calcification 74.26 34.27 10 414 322 63488276
Bronchial wall thickening 59.20 34.27 10 414 1489 63487109

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Broncholithiasis 77.07 35.43 10 540 232 79743606
Lymph node calcification 71.68 35.43 10 540 405 79743433
Bronchial wall thickening 53.19 35.43 10 540 2631 79741207

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000700 Analgesics
MeSH PA D018712 Analgesics, Non-Narcotic
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000894 Anti-Inflammatory Agents, Non-Steroidal
MeSH PA D018501 Antirheumatic Agents
MeSH PA D016861 Cyclooxygenase Inhibitors
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D018689 Sensory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Pain indication 22253000
Joint pain indication 57676002
Rheumatoid arthritis indication 69896004 DOID:7148
Bursitis indication 84017003 DOID:2965
Backache indication 161891005
Headache disorder indication 230461009
Dysmenorrhea indication 266599000
Fever indication 386661006
Osteoarthritis indication 396275006
Synovitis indication 416209007 DOID:2703
Shoulder Tendonitis indication
Tendinitis off-label use 34840004 DOID:971
Rheumatic fever off-label use 58718002 DOID:1586
Tenosynovitis off-label use 67801009 DOID:970
Juvenile rheumatoid arthritis off-label use 410795001
Necrotizing enterocolitis in fetus OR newborn contraindication 2707005
Ocular hypertension contraindication 4210003 DOID:9282
Gastritis contraindication 4556007 DOID:4029
Alcoholism contraindication 7200002
Peptic ulcer contraindication 13200003 DOID:750
Hyperthyroidism contraindication 34486009 DOID:7998
Hypertensive disorder contraindication 38341003 DOID:10763
Gastrointestinal ulcer contraindication 40845000
Body fluid retention contraindication 43498006
Conduction disorder of the heart contraindication 44808001
Disorder of cardiovascular system contraindication 49601007 DOID:1287
Vitamin K deficiency contraindication 52675005 DOID:11249
Nasal polyp contraindication 52756005
Hepatic failure contraindication 59927004
Blood coagulation disorder contraindication 64779008 DOID:1247
Hypermagnesemia contraindication 66978005
Poisoning by acetaminophen contraindication 70273001
Agoraphobia contraindication 70691001 DOID:593
Diabetes mellitus contraindication 73211009 DOID:9351
Factor II deficiency contraindication 73975000
Gastrointestinal hemorrhage contraindication 74474003
Thrombotic thrombocytopenic purpura contraindication 78129009 DOID:10772
Chronic idiopathic constipation contraindication 82934008
Gout contraindication 90560007 DOID:13189
Chronic renal failure syndrome contraindication 90688005
Kidney disease contraindication 90708001 DOID:557
Thyrotoxicosis contraindication 90739004 DOID:7997
Hemophilia contraindication 90935002
Anemia due to enzyme deficiency contraindication 111577008
Seizure disorder contraindication 128613002
Obsessive-compulsive disorder contraindication 191736004 DOID:10933
Insomnia contraindication 193462001
Impaired renal function disorder contraindication 197663003
Gastroesophageal reflux disease contraindication 235595009 DOID:8534
Disease of liver contraindication 235856003 DOID:409
Bladder outflow obstruction contraindication 236645006
Benign prostatic hyperplasia contraindication 266569009
Retention of urine contraindication 267064002
Anemia contraindication 271737000 DOID:2355
Pregnancy, function contraindication 289908002
Thrombocytopenic disorder contraindication 302215000 DOID:1588
Panic disorder contraindication 371631005 DOID:594
Angle-closure glaucoma contraindication 392291006 DOID:13550
Cardiovascular event risk contraindication 395112001
Breastfeeding (mother) contraindication 413712001
Myocardial ischemia contraindication 414795007 DOID:3393
Myocardial infarction in recovery phase contraindication 418044006




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00827 KEGG_DRUG
4018113 VUID
N0000146451 NUI
4018113 VANDF
CHEBI:6640 CHEBI
CHEMBL3989810 ChEMBL_ID
CHEMBL2106755 ChEMBL_ID
C496892 MESH_SUPPLEMENTAL_RECORD_UI
DB01397 DRUGBANK_ID
41728CY7UX UNII
218170 RXNORM
1469 MMSL
22065 MMSL
5016 MMSL
72175 MMSL
d00846 MMSL
001593 NDDF
370180006 SNOMEDCT_US
49399009 SNOMEDCT_US
C0126789 UMLSCUI
54684589 PUBCHEM_CID
18917-95-8 SECONDARY_CAS_RN

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
BACK RELIEF HUMAN OTC DRUG LABEL 2 0498-2101 TABLET 200 mg ORAL OTC monograph not final 15 sections
BACK RELIEF HUMAN OTC DRUG LABEL 2 0498-2102 TABLET 200 mg ORAL OTC monograph not final 15 sections
Zee Painaid Back Relief Formula HUMAN OTC DRUG LABEL 3 42961-027 tablet 290 mg ORAL OTC monograph not final 15 sections
First Aid Direct Backache and Muscle Relief HUMAN OTC DRUG LABEL 3 42961-111 TABLET 290 mg ORAL OTC monograph not final 9 sections
MEDIQUE Back Pain Off HUMAN OTC DRUG LABEL 3 47682-073 TABLET, FILM COATED 290 mg ORAL OTC monograph not final 16 sections
MEDIQUE Back Pain Off HUMAN OTC DRUG LABEL 3 47682-073 TABLET, FILM COATED 290 mg ORAL OTC monograph not final 16 sections
MEDIQUE Back Pain Off HUMAN OTC DRUG LABEL 3 47682-073 TABLET, FILM COATED 290 mg ORAL OTC monograph not final 16 sections
Medique Back Pain Relief HUMAN OTC DRUG LABEL 1 47682-074 TABLET, FILM COATED 580 mg ORAL OTC monograph not final 16 sections
Medique Back Pain Relief HUMAN OTC DRUG LABEL 1 47682-074 TABLET, FILM COATED 580 mg ORAL OTC monograph not final 16 sections
Medique at Home Back Pain Relief HUMAN OTC DRUG LABEL 1 47682-747 TABLET, FILM COATED 580 mg ORAL OTC monograph not final 16 sections
Unishield Back Pain Off HUMAN OTC DRUG LABEL 3 49314-0733 TABLET, FILM COATED 290 mg ORAL OTC monograph not final 17 sections
Unishield Back Pain Off HUMAN OTC DRUG LABEL 3 49314-0733 TABLET, FILM COATED 290 mg ORAL OTC monograph not final 17 sections
Unishield Back Pain Off HUMAN OTC DRUG LABEL 3 49314-0733 TABLET, FILM COATED 290 mg ORAL OTC monograph not final 17 sections
Unishield Back Pain Relief HUMAN OTC DRUG LABEL 1 49314-0748 TABLET, FILM COATED 580 mg ORAL OTC monograph not final 16 sections
Backprin HUMAN OTC DRUG LABEL 3 50332-0116 TABLET 290 mg ORAL OTC monograph not final 13 sections
BACKPRIN HUMAN OTC DRUG LABEL 1 50332-0140 TABLET, FILM COATED 580 mg ORAL OTC monograph not final 14 sections
DiurexWater Pills HUMAN OTC DRUG LABEL 2 52389-306 TABLET, COATED 162.50 mg ORAL OTC monograph not final 17 sections
DiurexWater Pills HUMAN OTC DRUG LABEL 2 52389-306 TABLET, COATED 162.50 mg ORAL OTC monograph not final 17 sections
Doans Extra Strength HUMAN OTC DRUG LABEL 1 55741-224 TABLET 580 mg ORAL OTC monograph not final 16 sections
Percogesic HUMAN OTC DRUG LABEL 1 63029-051 TABLET, COATED 467 mg ORAL OTC monograph not final 15 sections
VICA-CET HUMAN OTC DRUG LABEL 2 69103-2550 TABLET 250 mg ORAL OTC monograph not final 9 sections
Aramark Back Relief HUMAN OTC DRUG LABEL 3 81238-1118 TABLET 290 mg ORAL OTC monograph not final 10 sections