DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
racepinefrine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
sympathomimetic, phenethyl derivatives
4508
329-65-7
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
racepinephrine
epirenamine
racepinefrine
racepinephrine hydrochloride
racepinephrine HCl
A racemic mixture of d-epinephrine and l-epinephrine.
Molecular weight: 183.21
Formula: C9H13NO3
CLOGP: -0.68
LIPINSKI: 0
HAC: 4
HDO: 4
TPSA: 72.72
ALOGS: -0.99
ROTB: 3
Drug dosage:
None
ADMET properties:
None
Approvals:
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Date
Agency
Company
Orphan
None
FDA
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FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
CHEBI has role
CHEBI:77746
Homo sapiens metabolite
MeSH PA
D018663
Adrenergic Agents
MeSH PA
D000322
Adrenergic Agonists
MeSH PA
D000316
Adrenergic alpha-Agonists
MeSH PA
D000318
Adrenergic beta-Agonists
MeSH PA
D018927
Anti-Asthmatic Agents
MeSH PA
D001993
Bronchodilator Agents
MeSH PA
D002317
Cardiovascular Agents
MeSH PA
D009184
Mydriatics
MeSH PA
D018377
Neurotransmitter Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Hyperthyroidism
contraindication
34486009
DOID:7998
Hypertensive disorder
contraindication
38341003
DOID:10763
Cerebral arteriosclerosis
contraindication
65312002
Diabetes mellitus
contraindication
73211009
DOID:9351
Benign prostatic hyperplasia
contraindication
266569009
Angle-closure glaucoma
contraindication
392291006
DOID:13550
Peripheral vascular disease
contraindication
400047006
Disorder of coronary artery
contraindication
414024009
Showing 1 to 8 of 8 entries
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
9.97
acidic
pKa2
12.82
acidic
pKa3
13.64
acidic
pKa4
8.71
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Alpha-1A adrenergic receptor
GPCR
P35348
ADA1A_HUMAN
AGONIST
Ki
5
IUPHAR
Alpha-1D adrenergic receptor
GPCR
P25100
ADA1D_HUMAN
AGONIST
Ki
6
IUPHAR
Alpha-1B adrenergic receptor
GPCR
P35368
ADA1B_HUMAN
AGONIST
Ki
5.10
IUPHAR
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External reference:
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ID
Source
009897
NDDF
009898
NDDF
314610
RXNORM
329-63-5
SECONDARY_CAS_RN
4019263
VANDF
4023040
VUID
4023040
VANDF
415227003
SNOMEDCT_US
4553
INN_ID
5409
MMSL
Showing 1 to 10 of 21 entries
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Pharmaceutical products:
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Product
Category
Ingredients
NDC
Form
Quantity
Route
Marketing
Label
Asthmanefrin
HUMAN OTC DRUG LABEL
1
0487-2784
SOLUTION
11.25 mg
RESPIRATORY (INHALATION)
OTC monograph final
17 sections
Blue Gel Anesthetic
HUMAN OTC DRUG LABEL
3
80069-013
GEL
0.10 mg
TOPICAL
unapproved drug other
11 sections
Epi-Mist
HUMAN OTC DRUG LABEL
1
15343-125
AEROSOL, SPRAY
0.59 mg
RESPIRATORY (INHALATION)
OTC monograph final
10 sections
Racepinephrine
HUMAN OTC DRUG LABEL
1
68071-5149
SOLUTION
11.25 mg
RESPIRATORY (INHALATION)
OTC monograph final
17 sections
S2
HUMAN OTC DRUG LABEL
1
0487-5901
SOLUTION
11.25 mg
RESPIRATORY (INHALATION)
OTC monograph final
17 sections
S2 RacepinephrineMULTI-DOSE
HUMAN OTC DRUG LABEL
1
0487-5910
SOLUTION
11.25 mg
RESPIRATORY (INHALATION)
Export only
17 sections
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racepinefrine