isosulfan blue 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4503 68238-36-8

Description:

MoleculeDescription

Synonyms:

  • sulfan blue
  • isosulfan blue
  • lymphazurin
  • iso-sulfan blue
2,5-disulfobenzylidene-isomer of sulfan blue; RN given refers to Na salt
  • Molecular weight: 566.66
  • Formula: C27H31N2NaO6S2
  • CLOGP: -4.97
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 120.65
  • ALOGS: -6.28
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
July 29, 1981 FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Anaphylactic reaction 123.43 107.14 25 51 58970 56233021

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Anaphylactic reaction 109.20 108.71 22 43 74952 70853427

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D004396 Coloring Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04634 KEGG_DRUG
129-17-9 SECONDARY_CAS_RN
4019070 VANDF
CHEMBL1200859 ChEMBL_ID
CHEMBL1201275 ChEMBL_ID
C025484 MESH_SUPPLEMENTAL_RECORD_UI
C008769 MESH_SUPPLEMENTAL_RECORD_UI
DB09136 DRUGBANK_ID
39N9K8S2A4 UNII
27863 RXNORM
1330 MMSL
175443 MMSL
4936 MMSL
d01482 MMSL
003432 NDDF
009820 NDDF
109225006 SNOMEDCT_US
398766000 SNOMEDCT_US
C0063908 UMLSCUI
50108 PUBCHEM_CID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Isosulfan Blue HUMAN PRESCRIPTION DRUG LABEL 1 51808-206 SOLUTION 10 mg SUBCUTANEOUS Unapproved drug other 8 sections
Isosulfan Blue Human Prescription Drug Label 1 55150-240 INJECTION, SOLUTION 50 mg SUBCUTANEOUS ANDA 22 sections
Isosulfan Blue Human Prescription Drug Label 1 55150-240 INJECTION, SOLUTION 50 mg SUBCUTANEOUS ANDA 22 sections
LYMPHAZURIN HUMAN PRESCRIPTION DRUG LABEL 1 63261-250 INJECTION, SOLUTION 10 mg SUBCUTANEOUS NDA 23 sections
Isosulfan Blue HUMAN PRESCRIPTION DRUG LABEL 1 67457-220 INJECTION, SOLUTION 10 mg SUBCUTANEOUS ANDA 22 sections
Isosulfan Blue HUMAN PRESCRIPTION DRUG LABEL 1 70069-221 INJECTION, SOLUTION 10 mg SUBCUTANEOUS ANDA 22 sections
Isosulfan Blue HUMAN PRESCRIPTION DRUG LABEL 1 71288-805 INJECTION, SOLUTION 10 mg SUBCUTANEOUS ANDA 23 sections