All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

sodium fluoride F-18 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definition	Drug id	CAS RN
	4488	22554-99-0

Description:

Molecule	Description
Synonyms: sodium fluoride F-18 sodium fluoride-18F sodium fluoride (18F)	Molecular weight: 40.99 Formula: FNa CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

None

Approvals:

Date	Agency	Company	Orphan
Feb. 24, 1972	FDA	GE HEALTHCARE

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Walking aid user	128.52	27.26	60	6890	35446	90586051
Prescribed underdose	116.01	27.26	72	6878	74947	90546550
Wound infection	99.85	27.26	75	6875	106327	90515170
Seronegative arthritis	92.30	27.26	39	6911	18195	90603302
Upper respiratory tract infection	83.42	27.26	73	6877	128245	90493252
Spinal fusion surgery	78.32	27.26	31	6919	12252	90609245
Visual impairment	71.73	27.26	68	6882	132297	90489200
Joint dislocation	61.90	27.26	40	6910	44542	90576955
Spondylitis	60.86	27.26	27	6923	14151	90607346
Type 2 diabetes mellitus	60.26	27.26	76	6874	203168	90418329
Lupus vulgaris	59.07	27.26	39	6911	45020	90576477
Osteoporosis	56.92	27.26	52	6898	96479	90525018
Retinitis	54.61	27.26	35	6915	38423	90583074
Laryngitis	50.29	27.26	37	6913	50716	90570781
Hepatic cirrhosis	49.33	27.26	40	6910	63213	90558284
Wheezing	48.04	27.26	74	6876	238006	90383491
Lupus-like syndrome	47.03	27.26	35	6915	48811	90572686
Anti-cyclic citrullinated peptide antibody	46.83	27.26	28	6922	27193	90594304
Adjustment disorder with depressed mood	46.62	27.26	37	6913	56716	90564781
Foot deformity	45.00	27.26	37	6913	59614	90561883
Dislocation of vertebra	44.93	27.26	36	6914	55932	90565565
Joint stiffness	43.97	27.26	41	6909	78001	90543496
Drug ineffective	42.65	27.26	27	6923	1384271	89237226
Exostosis	40.16	27.26	33	6917	53101	90568396
Grip strength decreased	38.08	27.26	41	6909	92535	90528962
Prescribed overdose	38.00	27.26	42	6908	97583	90523914
Deep vein thrombosis postoperative	37.59	27.26	36	6914	70773	90550724
Hip arthroplasty	37.20	27.26	37	6913	76171	90545326
Osteoarthritis	36.91	27.26	59	6891	195671	90425826
Wound	36.32	27.26	75	6875	302905	90318592
Bone erosion	36.09	27.26	31	6919	52990	90568507
Liver function test increased	35.64	27.26	38	6912	84817	90536680
Red blood cell sedimentation rate increased	34.71	27.26	37	6913	82558	90538939
Oedema	34.56	27.26	58	6892	200237	90421260
Disability	34.39	27.26	27	6923	40718	90580779
Urticaria	33.54	27.26	74	6876	312660	90308837
Sciatica	33.37	27.26	40	6910	101342	90520155
Lower limb fracture	32.10	27.26	36	6914	84977	90536520
Autoimmune disorder	31.58	27.26	34	6916	76710	90544787
Delirium	30.84	27.26	39	6911	104320	90517177
Ear infection	30.63	27.26	32	6918	69743	90551754
Gait inability	30.18	27.26	46	6904	146410	90475087
Weight increased	30.16	27.26	85	6865	417842	90203655
Pulmonary fibrosis	29.92	27.26	39	6911	107464	90514033
Hypercholesterolaemia	28.70	27.26	37	6913	100855	90520642
Road traffic accident	28.34	27.26	38	6912	107588	90513909
Fibromyalgia	28.23	27.26	54	6896	206215	90415282
Swollen joint count increased	27.37	27.26	38	6912	111168	90510329
Breast cancer stage III	27.26	27.26	33	6917	84414	90537083

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Respiratory tract infection bacterial	129.21	39.85	22	498	1887	42618928
Respiratory tract infection viral	122.83	39.85	23	497	3383	42617432
Fibrin D dimer increased	79.10	39.85	17	503	4968	42615847
Respiratory tract infection	76.07	39.85	23	497	26299	42594516
Cytokine release syndrome	71.86	39.85	25	495	44502	42576313

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Respiratory tract infection bacterial	102.34	23.46	22	3537	2394	110583346
Respiratory tract infection viral	87.68	23.46	23	3536	5855	110579885
Fibrin D dimer increased	51.06	23.46	17	3542	9828	110575912
Cytokine release syndrome	44.80	23.46	28	3531	70278	110515462
Respiratory tract infection	34.61	23.46	24	3535	71593	110514147
Seronegative arthritis	31.94	23.46	13	3546	13164	110572576
Vertebral lateral recess stenosis	31.65	23.46	6	3553	346	110585394
Ligamentum flavum hypertrophy	31.27	23.46	6	3553	369	110585371
Osteoarthropathy	31.21	23.46	6	3553	373	110585367
Spinal fusion surgery	25.55	23.46	10	3549	9146	110576594
Toe operation	25.32	23.46	6	3553	1008	110584732

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	V09IX06	VARIOUS DIAGNOSTIC RADIOPHARMACEUTICALS TUMOUR DETECTION Other diagnostic radiopharmaceuticals for tumour detection
CHEBI has role	CHEBI:35610	antineoplastic agent

Related Drugs by ATC class:

V09IX Other diagnostic radiopharmaceuticals for tumour detection 10 drugs

fluciclovine (18F)fludeoxyglucose (18F)fluorodopa (18F)fluoroestradiol F 18fluoroethylcholine (18F)gallium (68Ga) edotreotidegallium (68Ga) gozetotideiobenguane (123I)iobenguane (131I)methionine

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
CHEBI:749312	CHEBI
CHEMBL1200744	ChEMBL_ID
9L75099X6R	UNII
1311495	RXNORM
235955	MMSL
26952	MMSL
d07542	MMSL
018450	NDDF
C0304965	UMLSCUI
23690531	PUBCHEM_CID

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Sodium FluorideF 18	HUMAN PRESCRIPTION DRUG LABEL	1	13267-542	INJECTION	600 mCi	INTRAVENOUS	ANDA	17 sections
Sodium Fluoride F 18	HUMAN PRESCRIPTION DRUG LABEL	1	24562-002	INJECTION, SOLUTION	200 mCi	INTRAVENOUS	ANDA	25 sections
Sodium Fluoride F 18	HUMAN PRESCRIPTION DRUG LABEL	1	40028-512	INJECTION, SOLUTION	200 mCi	INTRAVENOUS	ANDA	24 sections
Sodium Fluoride F 18	HUMAN PRESCRIPTION DRUG LABEL	1	49609-102	INJECTION	200 mCi	INTRAVENOUS	ANDA	25 sections
Sodium Fluoride F 18	HUMAN PRESCRIPTION DRUG LABEL	1	52670-550	INJECTION	91.50 mCi	INTRAVENOUS	ANDA	23 sections
Sodium FluorideF 18	HUMAN PRESCRIPTION DRUG LABEL	1	52768-125	INJECTION	200 mCi	INTRAVENOUS	ANDA	26 sections
Sodium FluorideF 18	HUMAN PRESCRIPTION DRUG LABEL	1	62072-500	INJECTION	200 mCi	INTRAVENOUS	ANDA	6 sections
Sodium FluorideF18	HUMAN PRESCRIPTION DRUG LABEL	1	65857-300	INJECTION	200 mCi	INTRAVENOUS	ANDA	24 sections
Sodium Fluoride F 18	HUMAN PRESCRIPTION DRUG LABEL	1	67939-020	INJECTION	200 mCi	INTRAVENOUS	ANDA	24 sections
Sodium FluorideF 18 F 18	HUMAN PRESCRIPTION DRUG LABEL	1	76167-002	INJECTION	200 mg	INTRAVENOUS	unapproved drug other	25 sections
Sodium Fluoride F 18	HUMAN PRESCRIPTION DRUG LABEL	1	76451-018	INJECTION	200 mCi	INTRAVENOUS	ANDA	25 sections
Sodium FluorideF 18	HUMAN PRESCRIPTION DRUG LABEL	1	81759-002	INJECTION	200 mCi	INTRAVENOUS	ANDA	17 sections