All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

potassium phosphate, monobasic 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4480	7778-77-0

Description:

Molecule	Description
Synonyms: potassium phosphate, monobasic potassium phosphate monobasic monobasic potassium phosphate	Molecular weight: 136.08 Formula: H2KO4P CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 80.59 ALOGS: ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Feb. 2, 1979	FDA	BAXTER HLTHCARE

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Toxic epidermal necrolysis	65.72	29.88	21	544	21625	34934741

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Toxic epidermal necrolysis	56.23	25.75	21	964	44560	79698843

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
CHEBI has role	CHEBI:33287	fertilizers

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Hypophosphatemia	off-label use	4996001
Calcium renal calculus	off-label use	427649000
Anuria	contraindication	2472002	DOID:2983
Hypocalcemia	contraindication	5291005
Hyperkalemia	contraindication	14140009
Cirrhosis of liver	contraindication	19943007	DOID:5082
Hyperphosphatemia	contraindication	20165001	DOID:0050459
Hypernatremia	contraindication	39355002
Body fluid retention	contraindication	43498006
Chronic heart failure	contraindication	48447003
Congenital myotonia, autosomal dominant form	contraindication	57938005
Acute nephropathy	contraindication	58574008
Hepatic failure	contraindication	59927004
Oliguria	contraindication	83128009
Hyporeninemic hypoaldosteronism	contraindication	236464008
Edema	contraindication	267038008
Azotemia	contraindication	445009001
Severe dehydration	contraindication	450316000

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strength	Trade name	Applicant	Application number	Approval date	Type	Dose form	Route	Patent number	Patent expiration date	Patent use
4.5GM/15ML (300MG/ML);2.65GM/15ML (175MG/ML)	POTASSIUM PHOSPHATES	CMP DEV LLC	N212121	Sept. 19, 2019	RX	SOLUTION	INTRAVENOUS	10632150	April 19, 2039	POTASSIUM PHOSPHATES INJECTION IS INDICATED AS A SOURCE OF PHOSPHORUS IN INTRAVENOUS FLUIDS TO CORRECT HYPOPHOSPHATEMIA IN ADULTS AND PEDIATRIC PATIENTS 12 YEARS OF AGE AND OLDER

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Intestinal alkaline phosphatase	Enzyme		PPBI_BOVIN		IC50	5.62		CHEMBL

External reference:

ID	Source
D02050	KEGG_DRUG
4018695	VUID
N0000147004	NUI
4018695	VANDF
CHEBI:63036	CHEBI
CHEMBL1200925	ChEMBL_ID
DB09413	DRUGBANK_ID
55019	RXNORM
5131	MMSL
5323	MMSL
NOCODE	MMSL
d01424	MMSL
001189	NDDF
002335	NDDF
61244006	SNOMEDCT_US
C0138038	UMLSCUI
516951	PUBCHEM_CID
4J9FJ0HL51	UNII

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Isolyte S pH 7.4	HUMAN PRESCRIPTION DRUG LABEL	7	0264-7707	INJECTION, SOLUTION	0.00 g	INTRAVENOUS	NDA	24 sections
Isolyte S pH 7.4	HUMAN PRESCRIPTION DRUG LABEL	7	0264-7707	INJECTION, SOLUTION	0.00 g	INTRAVENOUS	NDA	24 sections
Isolyte S pH 7.4	HUMAN PRESCRIPTION DRUG LABEL	7	0264-7707	INJECTION, SOLUTION	0.00 g	INTRAVENOUS	NDA	24 sections
Isolyte S pH 7.4	HUMAN PRESCRIPTION DRUG LABEL	7	0264-7707	INJECTION, SOLUTION	0.00 g	INTRAVENOUS	NDA	24 sections
Dextrose and Electrolyte No. 48	HUMAN PRESCRIPTION DRUG LABEL	6	0338-0143	INJECTION	20 mg	INTRAVENOUS	NDA	19 sections
Dextrose and Electrolyte No. 48	HUMAN PRESCRIPTION DRUG LABEL	6	0338-0143	INJECTION	20 mg	INTRAVENOUS	NDA	19 sections
Dextrose and Electrolyte No. 48	HUMAN PRESCRIPTION DRUG LABEL	6	0338-0143	INJECTION	20 mg	INTRAVENOUS	NDA	19 sections
Dextrose and Electrolyte No. 48	HUMAN PRESCRIPTION DRUG LABEL	6	0338-0143	INJECTION	20 mg	INTRAVENOUS	NDA	19 sections
TIS-U-SOL	HUMAN PRESCRIPTION DRUG LABEL	5	0338-0190	IRRIGANT	6.25 mg	IRRIGATION	NDA	5 sections
TIS-U-SOL	HUMAN PRESCRIPTION DRUG LABEL	5	0338-0190	IRRIGANT	6.25 mg	IRRIGATION	NDA	5 sections
TIS-U-SOL	HUMAN PRESCRIPTION DRUG LABEL	5	0338-0190	IRRIGANT	6.25 mg	IRRIGATION	NDA	5 sections
TIS-U-SOL	HUMAN PRESCRIPTION DRUG LABEL	5	0338-0190	IRRIGANT	6.25 mg	IRRIGATION	NDA	5 sections
Potassium Phosphates	HUMAN PRESCRIPTION DRUG LABEL	2	0409-7295	INJECTION, SOLUTION, CONCENTRATE	224 mg	INTRAVENOUS	UNAPPROVED DRUG OTHER	12 sections
Potassium Phosphates	HUMAN PRESCRIPTION DRUG LABEL	2	0409-7295	INJECTION, SOLUTION, CONCENTRATE	224 mg	INTRAVENOUS	UNAPPROVED DRUG OTHER	12 sections
Potassium Phosphates	HUMAN PRESCRIPTION DRUG LABEL	2	0409-7295	INJECTION, SOLUTION, CONCENTRATE	224 mg	INTRAVENOUS	UNAPPROVED DRUG OTHER	12 sections
Potassium Phosphates	HUMAN PRESCRIPTION DRUG LABEL	2	0409-7295	INJECTION, SOLUTION, CONCENTRATE	224 mg	INTRAVENOUS	UNAPPROVED DRUG OTHER	12 sections
Potassium Phosphates	HUMAN PRESCRIPTION DRUG LABEL	2	0409-7295	INJECTION, SOLUTION, CONCENTRATE	224 mg	INTRAVENOUS	UNAPPROVED DRUG OTHER	12 sections
Potassium Phosphates	HUMAN PRESCRIPTION DRUG LABEL	2	0409-7295	INJECTION, SOLUTION, CONCENTRATE	224 mg	INTRAVENOUS	UNAPPROVED DRUG OTHER	12 sections
K Phos Original	HUMAN PRESCRIPTION DRUG LABEL	1	0486-1111	TABLET, SOLUBLE	500 mg	ORAL	unapproved drug other	18 sections
K Phos Original	HUMAN PRESCRIPTION DRUG LABEL	1	0486-1111	TABLET, SOLUBLE	500 mg	ORAL	unapproved drug other	18 sections
K Phos Original	HUMAN PRESCRIPTION DRUG LABEL	1	0486-1111	TABLET, SOLUBLE	500 mg	ORAL	unapproved drug other	18 sections
K Phos Original	HUMAN PRESCRIPTION DRUG LABEL	1	0486-1111	TABLET, SOLUBLE	500 mg	ORAL	unapproved drug other	18 sections
K Phos Neutral	HUMAN PRESCRIPTION DRUG LABEL	3	0486-1125	TABLET, COATED	155 mg	ORAL	unapproved drug other	19 sections
K Phos Neutral	HUMAN PRESCRIPTION DRUG LABEL	3	0486-1125	TABLET, COATED	155 mg	ORAL	unapproved drug other	19 sections
K Phos Neutral	HUMAN PRESCRIPTION DRUG LABEL	3	0486-1125	TABLET, COATED	155 mg	ORAL	unapproved drug other	19 sections
K Phos Neutral	HUMAN PRESCRIPTION DRUG LABEL	3	0486-1125	TABLET, COATED	155 mg	ORAL	unapproved drug other	19 sections
K-Phos No. 2	HUMAN PRESCRIPTION DRUG LABEL	2	0486-1134	TABLET, COATED	305 mg	ORAL	unapproved drug other	18 sections
K-Phos No. 2	HUMAN PRESCRIPTION DRUG LABEL	2	0486-1134	TABLET, COATED	305 mg	ORAL	unapproved drug other	18 sections
K-Phos No. 2	HUMAN PRESCRIPTION DRUG LABEL	2	0486-1134	TABLET, COATED	305 mg	ORAL	unapproved drug other	18 sections
K-Phos No. 2	HUMAN PRESCRIPTION DRUG LABEL	2	0486-1134	TABLET, COATED	305 mg	ORAL	unapproved drug other	18 sections