menthyl salicylate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4460 89-46-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • menthyl salicylate, (+/-)-
  • menthyl salicylate
  • Molecular weight: 276.38
  • Formula: C17H24O3
  • CLOGP: 6.33
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 46.53
  • ALOGS: -4
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Urticaria thermal 63.26 29.70 11 1858 428 63486725
Administration site erythema 51.01 29.70 10 1859 755 63486398
Hypercholesterolaemia 49.95 29.70 20 1849 21314 63465839
Nail bed tenderness 37.58 29.70 7 1862 402 63486751
Pigmentation disorder 37.45 29.70 11 1858 4628 63482525
Vitamin B12 deficiency 35.99 29.70 11 1858 5292 63481861
Scratch 33.68 29.70 11 1858 6554 63480599
Dizziness postural 32.43 29.70 11 1858 7365 63479788
Type 2 diabetes mellitus 31.66 29.70 21 1848 63847 63423306
Skin plaque 31.13 29.70 11 1858 8309 63478844
Secretion discharge 30.47 29.70 12 1857 12219 63474934
Autonomic neuropathy 30.31 29.70 7 1862 1152 63486001

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Erythema multiforme 39.86 38.78 10 273 8639 34948009

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Urticaria thermal 68.71 26.51 11 1401 434 79742542
Administration site erythema 63.32 26.51 10 1402 361 79742615
Nail bed tenderness 41.06 26.51 7 1405 407 79742569
Pigmentation disorder 40.91 26.51 11 1401 5607 79737369
Vitamin B12 deficiency 38.14 26.51 11 1401 7230 79735746
Scratch 36.58 26.51 11 1401 8352 79734624
Secretion discharge 34.03 26.51 12 1400 15010 79727966
Skin plaque 33.86 26.51 11 1401 10734 79732242
Pruritus 33.68 26.51 38 1374 394610 79348366
Dizziness postural 33.08 26.51 11 1401 11538 79731438
Autonomic neuropathy 30.43 26.51 7 1405 1888 79741088
Dermatitis exfoliative 29.77 26.51 10 1402 10819 79732157
Vulvovaginal swelling 27.63 26.51 5 1407 410 79742566

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.91 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
CHEBI:135976 CHEBI
DB11201 DRUGBANK_ID
693797 PUBCHEM_CID
1368207 RXNORM
C2827258 UMLSCUI
43XOA705ZD UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Pain Relief Rub HUMAN OTC DRUG LABEL 3 36800-042 CREAM 30 g TOPICAL OTC monograph not final 13 sections
Topcare Pain Relieving 40ct HUMAN OTC DRUG LABEL 3 36800-679 PATCH 0.06 mg TOPICAL OTC monograph not final 14 sections
Topcare Pain Relieving 40ct HUMAN OTC DRUG LABEL 3 36800-679 PATCH 0.06 mg TOPICAL OTC monograph not final 14 sections
Muscle Rub Ultra HUMAN OTC DRUG LABEL 3 37808-773 CREAM 30 g TOPICAL OTC monograph not final 14 sections
Muscle Rub Ultra HUMAN OTC DRUG LABEL 3 37808-773 CREAM 30 g TOPICAL OTC monograph not final 14 sections
Muscle Rub Ultra HUMAN OTC DRUG LABEL 3 51141-0659 CREAM 30 g TOPICAL OTC monograph not final 28 sections
Pain Relief Rub HUMAN OTC DRUG LABEL 3 53943-992 CREAM 30 g TOPICAL OTC monograph not final 13 sections
TheraPlus Plus HUMAN OTC DRUG LABEL 2 55621-004 OINTMENT 15 g TOPICAL OTC monograph not final 8 sections
EXTRA STRENGTH HUA TUO MEDICATED PLASTER HUMAN OTC DRUG LABEL 3 61821-051 PLASTER 13.84 g TOPICAL OTC monograph not final 13 sections
Cold SpotPoint Relief HUMAN OTC DRUG LABEL 2 65121-001 GEL 19 mL TOPICAL OTC monograph final 8 sections
ZIMS MAX FREEZE HUMAN OTC DRUG LABEL 3 66902-113 PATCH 0.40 mg TRANSDERMAL OTC monograph not final 11 sections
Muscle Rub Ultra HUMAN OTC DRUG LABEL 3 67510-0659 CREAM 30 g TOPICAL OTC monograph not final 14 sections
Muscle Rub Ultra HUMAN OTC DRUG LABEL 3 67510-0659 CREAM 30 g TOPICAL OTC monograph not final 14 sections
pain relief patch HUMAN OTC DRUG LABEL 3 69963-001 PATCH 5 g TOPICAL OTC monograph not final 8 sections
Dr. Ds Super 7 Pain Relief HUMAN OTC DRUG LABEL 2 72246-112 CREAM 100 mg TOPICAL OTC monograph not final 14 sections
Pain Relieving Foot HUMAN OTC DRUG LABEL 2 72764-004 CREAM 750 mg TOPICAL OTC MONOGRAPH NOT FINAL 14 sections
Valtrum Analgesic HUMAN OTC DRUG LABEL 3 75849-312 GEL 100 mg TOPICAL OTC monograph not final 12 sections