menthyl salicylate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4460	89-46-3

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

menthyl salicylate, (+/-)-
menthyl salicylate

Molecular weight: 276.38
Formula: C17H24O3
CLOGP: 6.33
LIPINSKI: 1
HAC: 3
HDO: 1
TPSA: 46.53
ALOGS: -4
ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Nail bed tenderness	43.55	31.08	7	757	372	56290931
Autonomic neuropathy	36.20	31.08	7	757	1078	56290225

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Erythema multiforme	42.56	40.20	10	201	8061	31689072

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Nail bed tenderness	43.72	29.26	7	919	377	70927141
Autonomic neuropathy	33.18	29.26	7	919	1728	70925790
Dermatitis exfoliative	33.04	29.26	10	916	10541	70916977
Pruritus	31.71	29.26	30	896	345530	70581988
Vulvovaginal swelling	30.07	29.26	5	921	341	70927177

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.91	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
CHEBI:135976	CHEBI
DB11201	DRUGBANK_ID
43XOA705ZD	UNII
693797	PUBCHEM_CID
1368207	RXNORM
C2827258	UMLSCUI

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
Pain Relief Rub	HUMAN OTC DRUG LABEL	3	36800-042	CREAM	30 g	TOPICAL	OTC monograph not final	13 sections
Topcare Pain Relieving 40ct	HUMAN OTC DRUG LABEL	3	36800-679	PATCH	0.06 mg	TOPICAL	OTC monograph not final	14 sections
Muscle Rub Ultra	HUMAN OTC DRUG LABEL	3	37808-773	CREAM	30 g	TOPICAL	OTC monograph not final	14 sections
Muscle Rub Ultra	HUMAN OTC DRUG LABEL	3	51141-0659	CREAM	30 g	TOPICAL	OTC monograph not final	14 sections
Pain Relief Rub	HUMAN OTC DRUG LABEL	3	53943-992	CREAM	30 g	TOPICAL	OTC monograph not final	13 sections
TheraPlus Plus	HUMAN OTC DRUG LABEL	2	55621-004	OINTMENT	15 g	TOPICAL	OTC monograph not final	8 sections
EXTRA STRENGTH HUA TUO MEDICATED PLASTER	HUMAN OTC DRUG LABEL	3	61821-051	PLASTER	13.84 g	TOPICAL	OTC monograph not final	13 sections
Cold SpotPoint Relief	HUMAN OTC DRUG LABEL	2	65121-001	GEL	19 mL	TOPICAL	OTC monograph final	8 sections
ZIMS MAX FREEZE	HUMAN OTC DRUG LABEL	3	66902-113	PATCH	0.40 mg	TRANSDERMAL	OTC monograph not final	11 sections
Muscle Rub Ultra	HUMAN OTC DRUG LABEL	3	67510-0659	CREAM	30 g	TOPICAL	OTC monograph not final	14 sections
pain relief patch	HUMAN OTC DRUG LABEL	3	69963-001	PATCH	5 g	TOPICAL	OTC monograph not final	8 sections
Dr. Ds Super 7 Pain Relief	HUMAN OTC DRUG LABEL	2	72246-112	CREAM	100 mg	TOPICAL	OTC monograph not final	14 sections
Pain Relieving Foot	HUMAN OTC DRUG LABEL	2	72764-004	CREAM	750 mg	TOPICAL	OTC MONOGRAPH NOT FINAL	14 sections
Valtrum Analgesic	HUMAN OTC DRUG LABEL	3	75849-312	GEL	100 mg	TOPICAL	OTC monograph not final	12 sections