hydrocortisone succinate ๐Ÿถ Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
corticosteroids, except prednisolone derivatives 4456 125-04-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hydrocortisone sodium succinate
  • hydrocortisone succinate
  • hydrocortisone hemisuccinate
  • Molecular weight: 462.54
  • Formula: C25H34O8
  • CLOGP: 2.19
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 138.20
  • ALOGS: -3.85
  • ROTB: 7

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 0.23 mg/mL Bocci G, Oprea TI, Benet LZ

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2B,AXL,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PRKDC,TEK,TGFBR1 16
kinase-selectivity-class EIF2AK3,GRK2,MAP2K6 3
mdck-mdr1-bcrp-efflux MDCK-MDR1-BCRP efflux ratio 0.933 Moderate 0.70
pfas-class PFAS structural alert (1 = True, 0 = False) 0
rat-kpuu-brain Rat brain Kpuu 0.010 % Moderate 0.70

Approvals:

DateAgencyCompanyOrphan
April 27, 1955 FDA PHARMACIA AND UPJOHN

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Infusion related reaction 253.16 14.91 763 64157 416017 90147510
Rheumatic fever 221.42 14.91 395 64525 152726 90410801
Dislocation of vertebra 219.19 14.91 234 64686 55734 90507793
Drug ineffective 215.09 14.91 418 64502 1383880 89179647
Sciatica 205.72 14.91 305 64615 101077 90462450
Wound infection 200.15 14.91 309 64611 106093 90457434
Joint range of motion decreased 194.91 14.91 349 64571 135294 90428233
Adjustment disorder with depressed mood 194.07 14.91 221 64699 56532 90506995
Type 2 diabetes mellitus 192.89 14.91 440 64480 202804 90360723
Swollen joint count increased 191.30 14.91 310 64610 110896 90452631
Toxicity to various agents 182.91 14.91 5 64915 287841 90275686
Retinitis 179.98 14.91 177 64743 38281 90525246
Injury 178.21 14.91 419 64501 196930 90366597
Lupus-like syndrome 176.91 14.91 196 64724 48650 90514877
X-ray abnormal 167.50 14.91 184 64736 45240 90518287
Joint dislocation 165.10 14.91 181 64739 44401 90519126
Road traffic accident 161.13 14.91 282 64638 107344 90456183
Porphyria acute 160.82 14.91 120 64800 17855 90545672
Deep vein thrombosis postoperative 159.66 14.91 224 64696 70585 90492942
Facet joint syndrome 156.74 14.91 265 64655 98124 90465403
Impaired healing 155.51 14.91 443 64477 233756 90329771
Lower limb fracture 153.05 14.91 242 64678 84771 90478756
Walking aid user 150.70 14.91 155 64765 35351 90528176
Helicobacter infection 150.51 14.91 429 64491 226421 90337106
Grip strength decreased 145.69 14.91 248 64672 92328 90471199
Sleep disorder due to general medical condition, insomnia type 145.33 14.91 299 64621 128395 90435132
Fibromyalgia 144.61 14.91 398 64522 205871 90357656
Hypercholesterolaemia 144.13 14.91 259 64661 100633 90462894
Wheezing 140.59 14.91 432 64488 237648 90325879
Psoriatic arthropathy 140.15 14.91 420 64500 227915 90335612
Drug interaction 137.12 14.91 18 64902 276435 90287092
Urticaria 135.87 14.91 512 64408 312222 90251305
Prescribed underdose 132.89 14.91 212 64708 74807 90488720
Liver disorder 132.53 14.91 278 64642 120991 90442536
Fall 130.67 14.91 93 64827 481717 90081810
Lupus vulgaris 130.14 14.91 161 64759 44898 90518629
Delirium 129.23 14.91 252 64668 104107 90459420
Rheumatoid factor positive 125.08 14.91 336 64584 171314 90392213
Hepatic cirrhosis 124.98 14.91 188 64732 63065 90500462
Irritable bowel syndrome 123.92 14.91 378 64542 207070 90356457
Autoimmune disorder 121.28 14.91 206 64714 76538 90486989
Exostosis 121.12 14.91 169 64751 52965 90510562
Laryngitis 118.04 14.91 163 64757 50590 90512937
Lip dry 118.04 14.91 238 64682 100717 90462810
Folliculitis 113.41 14.91 363 64557 203990 90359537
Seronegative arthritis 112.62 14.91 98 64822 18136 90545391
Wound 109.14 14.91 468 64452 302512 90261015
Duodenal ulcer perforation 104.20 14.91 372 64548 220916 90342611
Foot deformity 102.12 14.91 166 64754 59485 90504042
Hand deformity 101.56 14.91 451 64469 295911 90267616
C-reactive protein abnormal 98.45 14.91 255 64665 127174 90436353
Bone erosion 98.27 14.91 153 64767 52868 90510659
Anti-cyclic citrullinated peptide antibody 98.15 14.91 109 64811 27112 90536415
Acute kidney injury 96.17 14.91 55 64865 320332 90243195
Pulmonary fibrosis 95.58 14.91 227 64693 107276 90456251
Hip arthroplasty 94.29 14.91 184 64736 76024 90487503
C-reactive protein 93.68 14.91 114 64806 31253 90532274
Ear infection 91.90 14.91 173 64747 69602 90493925
Ill-defined disorder 91.49 14.91 316 64604 184575 90378952
Hypoaesthesia 89.33 14.91 453 64467 313757 90249770
Muscle injury 89.23 14.91 304 64616 176350 90387177
Amnesia 87.82 14.91 221 64699 108284 90455243
Joint stiffness 87.68 14.91 181 64739 77861 90485666
Oedema 83.65 14.91 324 64596 199971 90363556
Prescribed overdose 83.40 14.91 203 64717 97422 90466105
Injection site pain 82.16 14.91 13 64907 173686 90389841
Disability 80.32 14.91 121 64799 40624 90522903
Infection 79.58 14.91 487 64433 361607 90201920
Glossodynia 79.25 14.91 446 64474 321333 90242194
Frequent bowel movements 78.53 14.91 144 64776 56791 90506736
Product dose omission issue 76.79 14.91 58 64862 291629 90271898
Inflammation 75.47 14.91 290 64630 178302 90385225
Dry mouth 75.44 14.91 296 64624 183763 90379764
Osteoporosis 75.40 14.91 194 64726 96337 90467190
Breast cancer stage III 74.71 14.91 178 64742 84269 90479258
Sleep disorder 73.64 14.91 309 64611 197721 90365806
Constipation 68.51 14.91 60 64860 280335 90283192
Colitis ulcerative 67.95 14.91 140 64780 60126 90503401
Liver injury 67.23 14.91 271 64649 170296 90393231
Visual impairment 67 14.91 228 64692 132137 90431390
Pericarditis 66.86 14.91 375 64545 269776 90293751
Feeling hot 64.28 14.91 160 64760 77848 90485679
Night sweats 63.60 14.91 220 64700 128546 90434981
Disease progression 63.18 14.91 17 64903 156598 90406929
Anaemia 63.03 14.91 97 64823 352705 90210822
Death 62.74 14.91 147 64773 456404 90107123
Red blood cell sedimentation rate increased 61.44 14.91 163 64757 82432 90481095
Gait inability 61.19 14.91 237 64683 146219 90417308
Synovitis 60.53 14.91 424 64496 329328 90234199
Hypersensitivity 60.10 14.91 542 64378 454135 90109392
Peripheral venous disease 59.79 14.91 163 64757 83758 90479769
Lung disorder 59.75 14.91 239 64681 149644 90413883
Knee arthroplasty 58.70 14.91 161 64759 83021 90480506
Somnolence 57.06 14.91 40 64880 209044 90354483
Weight increased 56.66 14.91 501 64419 417426 90146101
Musculoskeletal stiffness 56.61 14.91 385 64535 296147 90267380
Stomatitis 53.23 14.91 358 64562 274340 90289187
Hypertension 50.41 14.91 525 64395 457007 90106520
Urinary tract infection 49.95 14.91 89 64831 305543 90257984
Systemic lupus erythematosus 49.63 14.91 435 64485 361461 90202066
Intentional overdose 49.25 14.91 5 64915 93829 90469698
Spinal fusion surgery 49.20 14.91 52 64868 12231 90551296
Cerebrovascular accident 48.72 14.91 14 64906 123519 90440008
Malignant neoplasm progression 48.32 14.91 9 64911 106861 90456666
Sinusitis 47.36 14.91 413 64507 342675 90220852
Underdose 46.84 14.91 113 64807 53904 90509623
Spondylitis 44.74 14.91 53 64867 14125 90549402
Osteoarthritis 44.67 14.91 266 64654 195464 90368063
Discomfort 44.17 14.91 342 64578 273993 90289534
Hepatic enzyme increased 43.59 14.91 422 64498 360314 90203213
Neuropathy peripheral 43.27 14.91 22 64898 136948 90426579
Maternal exposure timing unspecified 43.22 14.91 66 64854 22417 90541110
Pulmonary embolism 42.86 14.91 20 64900 130800 90432727
Blood cholesterol increased 42.03 14.91 274 64646 207738 90355789
Obesity 41.84 14.91 168 64752 105339 90458188
Bursitis 41.77 14.91 196 64724 131458 90432069
Sleep disorder due to a general medical condition 41.40 14.91 96 64824 44642 90518885
Suicidal ideation 41.31 14.91 3 64917 73852 90489675
Chronic obstructive pulmonary disease 41.30 14.91 3 64917 73826 90489701
Blister 41.11 14.91 318 64602 254680 90308847
Injection site erythema 41.05 14.91 10 64910 98492 90465035
Seizure 40.59 14.91 30 64890 152599 90410928
Coma 40.49 14.91 3 64917 72629 90490898
Drug tolerance decreased 40.24 14.91 78 64842 32052 90531475
Balance disorder 40.18 14.91 10 64910 97070 90466457
Cough 40.10 14.91 133 64787 368829 90194698
Mobility decreased 40.04 14.91 312 64608 250422 90313105
Myocardial infarction 38.27 14.91 14 64906 105958 90457569
Intentional product use issue 36.93 14.91 274 64646 216618 90346909
Dehydration 35.13 14.91 53 64867 194394 90369133
Hypotension 34.87 14.91 118 64802 325279 90238248
Suicide attempt 34.84 14.91 6 64914 75393 90488134
Wrong technique in product usage process 34.65 14.91 5 64915 71566 90491961
Medication error 34.53 14.91 136 64784 84516 90479011
General physical health deterioration 34.25 14.91 397 64523 354718 90208809
Grip strength 34.22 14.91 37 64883 8928 90554599
Blood glucose increased 33.70 14.91 13 64907 95233 90468294
Nausea 33.22 14.91 578 64342 1109738 89453789
Pemphigus 33.13 14.91 369 64551 326495 90237032
Influenza 32.56 14.91 31 64889 139233 90424294
Weight fluctuation 32.49 14.91 54 64866 19695 90543832
Cardiac failure congestive 30.95 14.91 16 64904 98678 90464849
Atrial fibrillation 30.94 14.91 30 64890 133581 90429946
Mucosal inflammation 30.43 14.91 3 64917 57622 90505905
Hyponatraemia 29.76 14.91 31 64889 133507 90430020
Haemoglobin decreased 29.40 14.91 44 64876 161912 90401615
Cataract 28.74 14.91 8 64912 72084 90491443
Influenza like illness 28.52 14.91 11 64909 80600 90482927
Contusion 28.43 14.91 290 64630 250926 90312601
Swollen joint count 28.39 14.91 33 64887 8620 90554907
Fatigue 28.35 14.91 621 64299 1153402 89410125
Respiratory disorder 27.96 14.91 106 64814 64710 90498817
Musculoskeletal pain 27.82 14.91 214 64706 171037 90392490
Upper respiratory tract infection 27.74 14.91 172 64748 128146 90435381
Back pain 27.59 14.91 125 64795 317050 90246477
Gastrooesophageal reflux disease 27.55 14.91 48 64872 166289 90397238
Cardiac arrest 27.41 14.91 21 64899 104914 90458613
Bradycardia 27.18 14.91 13 64907 83834 90479693
Injection site swelling 27.13 14.91 5 64915 59834 90503693
Anti-cyclic citrullinated peptide antibody positive 26.31 14.91 272 64648 236161 90327366
Drug-induced liver injury 26.15 14.91 131 64789 90187 90473340
Neutropenia 25.86 14.91 79 64841 224825 90338702
Rectal haemorrhage 25.37 14.91 122 64798 82622 90480905
C-reactive protein increased 25.32 14.91 219 64701 181170 90382357
Vision blurred 25.26 14.91 25 64895 110268 90453259
Lethargy 25.18 14.91 7 64913 63132 90500395
Weight decreased 24.80 14.91 396 64524 379514 90184013
Herpes zoster 24.65 14.91 19 64901 94625 90468902
Swelling 24.49 14.91 429 64491 418629 90144898
Feeling abnormal 24.44 14.91 52 64868 167183 90396344
Renal failure 24.35 14.91 35 64885 130972 90432555
Syncope 24.11 14.91 36 64884 132627 90430900
Cognitive disorder 23.69 14.91 10 64910 69397 90494130
Subcutaneous drug absorption impaired 23.59 14.91 38 64882 13507 90550020
Cardiac disorder 23.26 14.91 6 64914 56866 90506661
Chronic kidney disease 23.18 14.91 4 64916 50187 90513340
Oedema peripheral 22.94 14.91 284 64636 257631 90305896
Thrombosis 22.78 14.91 12 64908 73239 90490288
Insomnia 22.67 14.91 350 64570 333124 90230403
Breast cancer stage II 22.58 14.91 66 64854 35268 90528259
Injection site bruising 22.41 14.91 5 64915 52302 90511225
Vertigo 22.36 14.91 11 64909 69800 90493727
Dyspnoea exertional 22.25 14.91 12 64908 72276 90491251
Overdose 22.25 14.91 50 64870 157659 90405868
Intentional product misuse 22.07 14.91 19 64901 89585 90473942
Unevaluable event 22.02 14.91 6 64914 54842 90508685
White blood cell count increased 21.97 14.91 101 64819 67140 90496387
Hyperhidrosis 21.97 14.91 40 64880 136265 90427262
Ascites 21.62 14.91 4 64916 47736 90515791
General symptom 21.36 14.91 38 64882 14630 90548897
Breast cancer stage I 21.02 14.91 30 64890 9594 90553933
Transient ischaemic attack 20.94 14.91 3 64917 43173 90520354
Pleural effusion 20.73 14.91 30 64890 111961 90451566
Femur fracture 20.57 14.91 4 64916 46078 90517449
Myalgia 20.50 14.91 61 64859 175064 90388463
Pruritus 20.43 14.91 520 64400 541005 90022522
Rheumatoid arthritis 20.41 14.91 164 64756 362450 90201077
Diverticulitis 20.01 14.91 4 64916 45183 90518344
Muscular weakness 19.87 14.91 231 64689 206435 90357092
Renal impairment 19.75 14.91 28 64892 105393 90458134
Pain in jaw 19.74 14.91 5 64915 47980 90515547
Deep vein thrombosis 19.60 14.91 22 64898 91598 90471929
Electrocardiogram QT prolonged 19.57 14.91 14 64906 72442 90491085
Dyspepsia 18.83 14.91 221 64699 197939 90365588
Pain 18.81 14.91 557 64363 995784 89567743
Epistaxis 18.70 14.91 20 64900 85105 90478422
Drug reaction with eosinophilia and systemic symptoms 18.49 14.91 4 64916 42754 90520773
Osteonecrosis of jaw 18.31 14.91 3 64917 39100 90524427
Colitis 18.26 14.91 14 64906 69928 90493599
COVID-19 18.22 14.91 61 64859 168782 90394745
Flushing 18.12 14.91 117 64803 88374 90475153
Abortion spontaneous 18.11 14.91 8 64912 54048 90509479
Adverse event 18.11 14.91 145 64775 117273 90446254
Sedation 18.02 14.91 6 64914 48165 90515362
Gastrointestinal haemorrhage 17.89 14.91 23 64897 90225 90473302
Rash vesicular 17.89 14.91 40 64880 18157 90545370
Liver function test abnormal 17.88 14.91 7 64913 50838 90512689
External ear cellulitis 17.81 14.91 7 64913 284 90563243
Endometritis decidual 17.65 14.91 4 64916 21 90563506
Flatulence 17.63 14.91 4 64916 41363 90522164
Dysphagia 17.17 14.91 34 64886 112244 90451283
Blood creatinine increased 17.02 14.91 29 64891 101357 90462170
Hypoglycaemia 16.97 14.91 15 64905 69833 90493694
Angioedema 16.92 14.91 13 64907 64863 90498664
Dysarthria 16.83 14.91 9 64911 54473 90509054
Swollen tongue 16.71 14.91 6 64914 45950 90517577
Cholestasis 16.53 14.91 3 64917 36296 90527231
Therapy non-responder 16.51 14.91 160 64760 136544 90426983
Injection site pruritus 16.47 14.91 9 64911 53825 90509702
Breast cancer 16.43 14.91 9 64911 53752 90509775
Asthma 16.38 14.91 254 64666 241906 90321621
Loss of consciousness 16.30 14.91 49 64871 140189 90423338
Hallucination 16.23 14.91 14 64906 65945 90497582
Haematoma 16.20 14.91 4 64916 39044 90524483
Lactic acidosis 16.09 14.91 8 64912 50455 90513072
Skin exfoliation 16.01 14.91 15 64905 67898 90495629
Live birth 15.83 14.91 104 64816 79003 90484524
Interstitial lung disease 15.64 14.91 19 64901 76386 90487141
Polyglandular disorder 15.64 14.91 6 64914 228 90563299
Asthenia 15.51 14.91 279 64641 533472 90030055
Hypercalcaemia 15.23 14.91 3 64917 34237 90529290
Hepatitis 15.11 14.91 17 64903 70722 90492805
Rhabdomyolysis 15.07 14.91 9 64911 51247 90512280
Depressed level of consciousness 15.00 14.91 18 64902 72766 90490761
Foetal exposure during pregnancy 14.98 14.91 6 64914 42969 90520558
Myelosuppression 14.94 14.91 10 64910 53581 90509946

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Infusion related reaction 313.13 14.88 220 14949 60586 42545580
Nipple swelling 99.40 14.88 24 15145 373 42605793
Mechanical ventilation complication 85.76 14.88 24 15145 680 42605486
Nipple pain 79.62 14.88 25 15144 1062 42605104
Anaphylactic reaction 64.84 14.88 78 15091 42665 42563501
Anaphylactic shock 60.80 14.88 57 15112 23460 42582706
Pyrexia 60.22 14.88 288 14881 393754 42212412
Disseminated intravascular coagulation 56.38 14.88 56 15113 24738 42581428
Urticaria 54.63 14.88 96 15073 73940 42532226
Flushing 53.60 14.88 66 15103 36962 42569204
Inspiratory capacity decreased 48.94 14.88 23 15146 2944 42603222
Febrile neutropenia 47.85 14.88 160 15009 185543 42420623
Haemothorax 44.41 14.88 26 15143 5210 42600956
Blood pressure fluctuation 43.93 14.88 51 15118 26857 42579309
Adverse reaction 42.47 14.88 23 15146 3970 42602196
Polyp 42.03 14.88 24 15145 4590 42601576
Blood iron decreased 39.91 14.88 26 15143 6292 42599874
Toxicity to various agents 39.63 14.88 16 15153 229120 42377046
Angiopathy 38.63 14.88 24 15145 5353 42600813
Platelet count decreased 36.18 14.88 120 15049 138461 42467705
Blood pressure increased 32.85 14.88 95 15074 101833 42504333
Drug interaction 31.75 14.88 29 15140 266970 42339196
Face oedema 31.30 14.88 31 15138 13635 42592531
Death 31.04 14.88 77 15092 471108 42135058
Chills 30.62 14.88 88 15081 93978 42512188
Large intestine polyp 28.96 14.88 25 15144 9240 42596926
Cerebellar tumour 27.92 14.88 7 15162 128 42606038
Enterococcus test positive 27.60 14.88 13 15156 1672 42604494
Frequent bowel movements 27.55 14.88 36 15133 21371 42584795
Hypersensitivity 26.82 14.88 71 15098 72299 42533867
Emphysema 25.55 14.88 26 15143 11809 42594357
Neutrophil count decreased 25.33 14.88 64 15105 63351 42542815
Myoglobinaemia 24.92 14.88 7 15162 201 42605965
Overdose 24.55 14.88 4 15165 105260 42500906
Blood pressure decreased 24.49 14.88 60 15109 58272 42547894
Septic shock 24.45 14.88 80 15089 91592 42514574
Shock haemorrhagic 23.57 14.88 29 15140 16213 42589953
Oxygen saturation decreased 23.50 14.88 63 15106 64624 42541542
Posthaemorrhagic hydrocephalus 23.42 14.88 6 15163 120 42606046
Adrenal insufficiency 23.08 14.88 31 15138 18893 42587273
Off label use 22.68 14.88 335 14834 638000 41968166
Therapeutic product effect prolonged 21.99 14.88 7 15162 311 42605855
Intentional product use issue 21.27 14.88 65 15104 71768 42534398
Hypovolaemia 20.83 14.88 23 15146 11462 42594704
Pneumothorax 20.64 14.88 33 15136 23510 42582656
Middle ear inflammation 20.50 14.88 6 15163 200 42605966
Cytomegalovirus infection 20.16 14.88 39 15130 32267 42573899
Pituitary tumour recurrent 19.97 14.88 5 15164 91 42606075
Abdominal discomfort 19.46 14.88 65 15104 75190 42530976
Steroid dependence 18.74 14.88 17 15152 6705 42599461
Cytomegalovirus test positive 18.47 14.88 14 15155 4305 42601861
White blood cell count decreased 18.43 14.88 83 15086 110313 42495853
Antithrombin III decreased 17.95 14.88 7 15162 567 42605599
Product use issue 17.85 14.88 64 15105 76687 42529479
Engraft failure 17.84 14.88 7 15162 576 42605590
Epstein-Barr virus associated lymphoproliferative disorder 17.79 14.88 11 15158 2432 42603734
Heart rate irregular 17.63 14.88 25 15144 16025 42590141
Herpes dermatitis 17.62 14.88 5 15164 149 42606017
Vein rupture 17.42 14.88 8 15161 971 42605195
Acute graft versus host disease in skin 17.30 14.88 17 15152 7407 42598759
Infection 17.04 14.88 82 15087 111986 42494180
Pallor 16.97 14.88 34 15135 28852 42577314
Impaired quality of life 16.95 14.88 23 15146 14154 42592012
Heart rate decreased 16.87 14.88 39 15130 36493 42569673
Anaplastic large cell lymphoma T- and null-cell types recurrent 16.82 14.88 4 15165 58 42606108
Chest discomfort 16.49 14.88 55 15114 63561 42542605
Hypopnoea 16.44 14.88 17 15152 7865 42598301
Catarrh 16.41 14.88 15 15154 5971 42600195
Burns second degree 16.18 14.88 15 15154 6081 42600085
Sleep disorder due to a general medical condition 16.04 14.88 25 15144 17428 42588738
Cytomegalovirus viraemia 15.82 14.88 19 15150 10358 42595808
Traumatic shock 15.81 14.88 3 15166 13 42606153
Hepatic function abnormal 15.58 14.88 47 15122 51520 42554646
Myocardial infarction 15.28 14.88 13 15156 123996 42482170
Leukaemia recurrent 15.08 14.88 9 15160 1867 42604299

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Infusion related reaction 328.93 13.97 711 65235 380451 110142902
Rheumatic fever 245.56 13.97 333 65613 122246 110401107
X-ray abnormal 227.92 13.97 186 65760 37931 110485422
Toxicity to various agents 216.55 13.97 19 65927 480536 110042817
Sleep disorder due to general medical condition, insomnia type 213.11 13.97 288 65658 105355 110417998
Facet joint syndrome 207.65 13.97 272 65674 96556 110426797
Swollen joint count increased 196.69 13.97 246 65700 83415 110439938
Porphyria acute 190.28 13.97 126 65820 18654 110504699
Sciatica 177.44 13.97 246 65700 92153 110431200
Dislocation of vertebra 173.10 13.97 169 65777 43552 110479801
Ill-defined disorder 172.48 13.97 324 65622 156529 110366824
Type 2 diabetes mellitus 171.66 13.97 347 65599 176885 110346468
Drug interaction 164.90 13.97 47 65899 500136 110023217
Psoriatic arthropathy 164.76 13.97 363 65583 196398 110326955
Liver disorder 157.85 13.97 295 65651 141948 110381405
Lip dry 156.72 13.97 242 65704 99841 110423512
Fibromyalgia 155.36 13.97 326 65620 170583 110352770
Urticaria 154.34 13.97 479 65467 318378 110204975
Injury 154.06 13.97 332 65614 176933 110346420
Helicobacter infection 149.40 13.97 333 65613 181544 110341809
Adjustment disorder with depressed mood 147.02 13.97 155 65791 43728 110479625
Joint range of motion decreased 139.34 13.97 256 65690 121576 110401777
C-reactive protein abnormal 134.06 13.97 261 65685 129434 110393919
Rheumatoid factor positive 133.74 13.97 263 65683 131377 110391976
Impaired healing 126.90 13.97 328 65618 196389 110326964
Hand deformity 126.50 13.97 350 65596 218156 110305197
Fall 126.02 13.97 105 65841 603377 109919976
Frequent bowel movements 123.68 13.97 181 65765 71209 110452144
Wound 123.55 13.97 363 65583 234074 110289279
Road traffic accident 123.22 13.97 226 65720 107172 110416181
Folliculitis 122.31 13.97 293 65653 167360 110355993
Lower limb fracture 119.07 13.97 183 65763 75165 110448188
Systemic lupus erythematosus 118.34 13.97 377 65569 253961 110269392
Irritable bowel syndrome 117.66 13.97 285 65661 163930 110359423
Wound infection 117.05 13.97 208 65738 96257 110427096
Duodenal ulcer perforation 116.37 13.97 298 65648 177402 110345951
Glossodynia 116.27 13.97 343 65603 221661 110301692
C-reactive protein 115.88 13.97 115 65831 30216 110493137
Retinitis 115.14 13.97 118 65828 32209 110491144
Lupus-like syndrome 113.98 13.97 131 65815 40661 110482692
Acute kidney injury 113.57 13.97 127 65819 635303 109888050
Deep vein thrombosis postoperative 112.52 13.97 157 65789 59134 110464219
Death 102.17 13.97 162 65784 698707 109824646
Inflammation 101.59 13.97 299 65647 192939 110330414
Muscle injury 101.52 13.97 245 65701 140562 110382791
Dry mouth 96.29 13.97 300 65646 199648 110323705
Infection 95.98 13.97 449 65497 361751 110161602
Night sweats 90.10 13.97 227 65719 133756 110389597
Wheezing 89.00 13.97 344 65602 254886 110268467
Nipple swelling 87.09 13.97 24 65922 373 110522980
Hypersensitivity 86.76 13.97 472 65474 403526 110119827
Sleep disorder 82.13 13.97 283 65663 198361 110324992
Synovitis 81.75 13.97 352 65594 273740 110249613
Peripheral venous disease 80.54 13.97 164 65782 83953 110439400
Grip strength decreased 79.97 13.97 159 65787 80015 110443338
Drug ineffective 79.74 13.97 556 65390 1519984 109003369
Feeling hot 78.36 13.97 170 65776 90936 110432417
Mechanical ventilation complication 75.36 13.97 25 65921 746 110522607
Intentional product use issue 75.18 13.97 320 65626 247586 110275767
Autoimmune disorder 74.08 13.97 137 65809 65346 110458007
Pericarditis 72.06 13.97 290 65656 218824 110304529
Stomatitis 71.53 13.97 335 65611 269907 110253446
Colitis ulcerative 70.73 13.97 148 65798 77215 110446138
Pemphigus 69.78 13.97 283 65663 214287 110309066
Lupus vulgaris 67.70 13.97 92 65854 33791 110489562
Lung disorder 67.14 13.97 248 65698 179799 110343554
Bursitis 66.32 13.97 199 65747 129719 110393634
Sinusitis 65.93 13.97 350 65596 296338 110227015
Underdose 63.33 13.97 126 65820 63428 110459925
Laryngitis 62.81 13.97 100 65846 42311 110481042
Discomfort 61.90 13.97 273 65673 214434 110308919
Nipple pain 61.90 13.97 24 65922 1132 110522221
Weight increased 59.97 13.97 442 65504 419202 110104151
Maternal exposure timing unspecified 59.57 13.97 68 65878 20945 110502408
Exostosis 59.50 13.97 102 65844 45854 110477499
Liver injury 59.31 13.97 211 65735 150202 110373151
Anaemia 59.15 13.97 151 65795 546935 109976418
Drug tolerance decreased 58.43 13.97 77 65869 27463 110495890
Delirium 58.10 13.97 195 65751 134830 110388523
Myocardial infarction 57.98 13.97 21 65925 192062 110331291
Swelling 57.94 13.97 383 65563 350658 110172695
Intentional overdose 57.59 13.97 6 65940 132495 110390858
Obesity 57.26 13.97 173 65773 113178 110410175
Pulmonary fibrosis 56.58 13.97 161 65785 101881 110421472
Prescribed overdose 56.39 13.97 146 65800 87435 110435918
Breast cancer stage III 56.29 13.97 137 65809 78980 110444373
Walking aid user 56.15 13.97 72 65874 25003 110498350
Injection site pain 54.48 13.97 19 65927 177903 110345450
Joint dislocation 52.54 13.97 82 65864 34108 110489245
Amnesia 52.42 13.97 160 65786 105248 110418105
Oedema 50.29 13.97 253 65693 209723 110313630
Musculoskeletal stiffness 49.66 13.97 311 65635 279511 110243842
Somnolence 49.26 13.97 63 65883 297386 110225967
Hypercholesterolaemia 49.08 13.97 142 65804 90695 110432658
Disease progression 47.78 13.97 45 65901 243989 110279364
Product dose omission issue 47.48 13.97 74 65872 321708 110201645
Chronic obstructive pulmonary disease 47.29 13.97 5 65941 109153 110414200
Weight fluctuation 47.11 13.97 62 65884 22083 110501270
Prescribed underdose 46.51 13.97 113 65833 65061 110458292
Hepatic enzyme increased 45.81 13.97 338 65608 320554 110202799
Ear infection 45.02 13.97 109 65837 62623 110460730
Hypoaesthesia 44.87 13.97 331 65615 313892 110209461
Blister 44.33 13.97 259 65687 227117 110296236
Musculoskeletal pain 43.45 13.97 220 65726 182803 110340550
Foot deformity 43.44 13.97 92 65854 48388 110474965
Grip strength 43.20 13.97 39 65907 9102 110514251
Medication error 42.55 13.97 149 65797 105217 110418136
Hypertension 42.47 13.97 478 65468 509606 110013747
Respiratory disorder 41.90 13.97 115 65831 71267 110452086
Suicide attempt 41.70 13.97 6 65940 103388 110419965
Hip arthroplasty 41.15 13.97 98 65848 55715 110467638
Inspiratory capacity decreased 40.63 13.97 23 65923 2572 110520781
Constipation 40.00 13.97 97 65849 357689 110165664
Bone erosion 39.26 13.97 86 65860 46285 110477068
Insomnia 39.17 13.97 357 65589 360233 110163120
Subcutaneous drug absorption impaired 38.83 13.97 34 65912 7625 110515728
Product use issue 38.23 13.97 317 65629 311378 110211975
Breast cancer stage II 37.08 13.97 62 65884 27313 110496040
Dehydration 36.90 13.97 69 65877 279442 110243911
Blood pressure fluctuation 36.66 13.97 113 65833 74711 110448642
General symptom 36.52 13.97 35 65911 8811 110514542
Hyponatraemia 36.13 13.97 46 65900 217607 110305746
Gastrointestinal disorder 35.75 13.97 257 65689 241695 110281658
Swollen joint count 35.20 13.97 34 65912 8640 110514713
Lower respiratory tract infection 34.64 13.97 256 65690 242850 110280503
Urinary tract infection 34.50 13.97 91 65855 326191 110197162
Disseminated intravascular coagulation 34.31 13.97 76 65870 41210 110482143
Disability 33.88 13.97 63 65883 30160 110493193
Blood cholesterol increased 33.78 13.97 207 65739 184578 110338775
Intentional product misuse 33.14 13.97 19 65927 132885 110390468
Wrong technique in product usage process 33.14 13.97 6 65940 87342 110436011
Mobility decreased 32.69 13.97 248 65698 237174 110286179
Malignant neoplasm progression 32.09 13.97 34 65912 174533 110348820
Pulmonary embolism 31.93 13.97 49 65897 214425 110308928
Atrial fibrillation 31.82 13.97 55 65891 229587 110293766
Neuropathy peripheral 31.76 13.97 36 65910 179241 110344112
Gait inability 31.71 13.97 163 65783 136213 110387140
Anti-cyclic citrullinated peptide antibody positive 31.48 13.97 201 65745 181783 110341570
Cerebrovascular accident 31.47 13.97 37 65909 181247 110342106
Live birth 31.35 13.97 102 65844 69382 110453971
Pyrexia 31.30 13.97 728 65218 897537 109625816
Osteoporosis 30.77 13.97 118 65828 87034 110436319
Sleep disorder due to a general medical condition 30.63 13.97 84 65862 52028 110471325
Overdose 30.60 13.97 58 65888 233736 110289617
Suicidal ideation 30.58 13.97 9 65937 93928 110429425
Syncope 29.46 13.97 47 65899 202489 110320864
Coma 29.18 13.97 17 65929 117852 110405501
Haemoglobin decreased 28.93 13.97 66 65880 248661 110274692
Adverse event 28.83 13.97 135 65811 108674 110414679
Myalgia 28.38 13.97 56 65890 222325 110301028
Neutropenia 28.28 13.97 121 65825 374499 110148854
Bradycardia 27.80 13.97 31 65915 155486 110367867
Rectal haemorrhage 27.70 13.97 143 65803 119690 110403663
Hepatic cirrhosis 27.62 13.97 96 65850 67530 110455823
Transient ischaemic attack 27.53 13.97 3 65943 63979 110459374
Knee arthroplasty 27.22 13.97 93 65853 64855 110458498
Transaminases increased 27.21 13.97 3 65943 63387 110459966
Cardiac failure congestive 27.10 13.97 30 65916 150970 110372383
Osteoarthritis 25.83 13.97 192 65754 182431 110340922
Dyspnoea exertional 25.77 13.97 15 65931 104045 110419308
Injection site erythema 25.65 13.97 12 65934 94164 110429189
Pruritus 25.30 13.97 487 65459 581073 109942280
Migraine 25.15 13.97 182 65764 171470 110351883
Seronegative arthritis 25.15 13.97 35 65911 13142 110510211
Coronary artery disease 24.98 13.97 6 65940 71684 110451669
Aggression 24.92 13.97 3 65943 59207 110464146
Pregnancy 24.90 13.97 77 65869 50990 110472363
Anaphylactic shock 24.46 13.97 77 65869 51469 110471884
Nausea 24.24 13.97 557 65389 1235133 109288220
Blood glucose increased 24.13 13.97 26 65920 132470 110390883
Dysarthria 24.05 13.97 10 65936 84111 110439242
Sedation 23.95 13.97 6 65940 69677 110453676
Lethargy 23.88 13.97 13 65933 93563 110429790
Cardiac arrest 23.87 13.97 51 65895 196702 110326651
Haemothorax 23.83 13.97 25 65921 7006 110516347
Contusion 23.79 13.97 228 65718 233133 110290220
Rash vesicular 23.72 13.97 36 65910 14616 110508737
Rash 23.44 13.97 648 65298 820316 109703037
Cough 23.43 13.97 170 65776 461471 110061882
Pancreatitis 23.30 13.97 114 65832 93419 110429934
Ear pain 23.00 13.97 77 65869 53149 110470204
Red blood cell sedimentation rate increased 22.87 13.97 100 65846 78202 110445151
Pustular psoriasis 22.84 13.97 34 65912 13571 110509782
Gastrointestinal haemorrhage 22.60 13.97 40 65906 165478 110357875
Cognitive disorder 22.56 13.97 12 65934 87499 110435854
Thrombosis 22.50 13.97 19 65927 108643 110414710
Seizure 22.38 13.97 63 65883 221122 110302231
Balance disorder 22.22 13.97 22 65924 116538 110406815
Orthostatic hypotension 22.21 13.97 6 65940 66243 110457110
Hallucination 21.92 13.97 17 65929 101415 110421938
Cerebellar tumour 21.87 13.97 7 65939 186 110523167
Rheumatoid arthritis 21.86 13.97 98 65848 299515 110223838
Electrocardiogram QT prolonged 21.43 13.97 20 65926 108940 110414413
Lactic acidosis 20.77 13.97 15 65931 92796 110430557
Ascites 20.77 13.97 15 65931 92793 110430560
Pain in jaw 20.56 13.97 3 65943 51174 110472179
Renal failure 20.46 13.97 68 65878 226506 110296847
Anti-cyclic citrullinated peptide antibody 20.39 13.97 40 65906 19924 110503429
Therapy non-responder 20.35 13.97 162 65784 157145 110366208
Flushing 20.20 13.97 119 65827 104617 110418736
Injection site swelling 19.96 13.97 6 65940 61784 110461569
White blood cell count increased 19.96 13.97 112 65834 96730 110426623
Diverticulitis 19.62 13.97 4 65942 53518 110469835
Cholestasis 19.55 13.97 7 65939 64511 110458842
International normalised ratio increased 19.45 13.97 14 65932 86758 110436595
Drug resistance 19.10 13.97 5 65941 56369 110466984
Anaphylactic reaction 18.99 13.97 125 65821 114175 110409178
Joint swelling 18.95 13.97 370 65576 442475 110080878
Chronic kidney disease 18.89 13.97 11 65935 76280 110447073
Cardiac disorder 18.88 13.97 11 65935 76269 110447084
Influenza like illness 18.88 13.97 15 65931 88397 110434956
Osteonecrosis of jaw 18.87 13.97 3 65943 48014 110475339
Mental status changes 18.81 13.97 11 65935 76111 110447242
Metabolic acidosis 18.81 13.97 19 65927 99725 110423628
Cardio-respiratory arrest 18.68 13.97 25 65921 115811 110407542
Cytomegalovirus viraemia 18.64 13.97 36 65910 17728 110505625
Therapeutic product effect decreased 18.53 13.97 225 65721 244091 110279262
Angioedema 18.31 13.97 19 65927 98481 110424872
Acute myocardial infarction 18.16 13.97 14 65932 83763 110439590
Myoglobinaemia 17.99 13.97 6 65940 182 110523171
Cardiac failure 17.85 13.97 55 65891 187571 110335782
Abdominal discomfort 17.85 13.97 332 65614 393526 110129827
Hypoglycaemia 17.78 13.97 26 65920 116078 110407275
Skin ulcer 17.50 13.97 8 65938 63637 110459716
Joint stiffness 17.50 13.97 83 65863 67160 110456193
Drug reaction with eosinophilia and systemic symptoms 17.44 13.97 14 65932 82081 110441272
Hepatotoxicity 17.39 13.97 8 65938 63392 110459961
Adverse drug reaction 17.27 13.97 115 65831 105444 110417909
Adrenal insufficiency 17.15 13.97 60 65886 42330 110481023
Throat irritation 16.88 13.97 70 65876 53482 110469871
Irritability 16.66 13.97 4 65942 47805 110475548
Injection site bruising 16.52 13.97 5 65941 51258 110472095
Muscle spasms 16.48 13.97 245 65701 277912 110245441
Feeling abnormal 16.47 13.97 54 65892 180657 110342696
Polyglandular disorder 16.41 13.97 6 65940 240 110523113
Angiopathy 16.38 13.97 23 65923 8707 110514646
Middle ear inflammation 16.25 13.97 6 65940 247 110523106
Oropharyngeal discomfort 16.19 13.97 25 65921 10302 110513051
Interstitial lung disease 16.17 13.97 37 65909 139297 110384056
Dysphagia 16.10 13.97 43 65903 153557 110369796
Hepatitis 16.04 13.97 18 65928 90036 110433317
Hypotension 16.03 13.97 218 65728 523631 109999722
Accidental exposure to product 15.90 13.97 5 65941 50003 110473350
Obstructive airways disorder 15.81 13.97 4 65942 46145 110477208
Liver function test abnormal 15.62 13.97 11 65935 68939 110454414
External ear cellulitis 15.62 13.97 6 65940 276 110523077
Angina pectoris 15.39 13.97 9 65937 62286 110461067
Antithrombin III decreased 15.13 13.97 7 65939 513 110522840
Arthropathy 15.04 13.97 248 65698 287274 110236079
Visual impairment 15.03 13.97 134 65812 134294 110389059
Laboratory test abnormal 15.00 13.97 59 65887 44020 110479333
Enterococcus test positive 14.94 13.97 13 65933 2891 110520462
Gastrooesophageal reflux disease 14.92 13.97 56 65890 179920 110343433
Apocrine miliaria 14.88 13.97 3 65943 10 110523343
Exposure during pregnancy 14.86 13.97 159 65787 167265 110356088
Generalised tonic-clonic seizure 14.84 13.97 7 65939 54673 110468680
Unresponsive to stimuli 14.69 13.97 10 65936 63780 110459573
Onychomadesis 14.64 13.97 60 65886 45603 110477750
Arrhythmia 14.61 13.97 12 65934 69563 110453790
Hepatocellular injury 14.51 13.97 6 65940 50636 110472717
Anaplastic large cell lymphoma T- and null-cell types recurrent 14.35 13.97 4 65942 65 110523288
Hypercalcaemia 14.24 13.97 5 65941 46652 110476701
Rash maculo-papular 14.15 13.97 14 65932 74208 110449145
Pituitary tumour recurrent 14.10 13.97 5 65941 183 110523170
Polyp 14.05 13.97 23 65923 9957 110513396

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:65023 anti-asthmatic agent

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Disorder of musculoskeletal system indication 928000 DOID:17
Cerebral edema indication 2032001
Berylliosis indication 8247009 DOID:10322
Psoriasis indication 9014002 DOID:8893
Ankylosing spondylitis indication 9631008 DOID:7147
Rheumatic heart disease indication 23685000
Atopic dermatitis indication 24079001 DOID:3310
Inflammatory bowel disease indication 24526004 DOID:0050589
Multiple sclerosis indication 24700007 DOID:2377
Severe adrenal insufficiency indication 24867002
Sarcoidosis indication 31541009 DOID:11335
Idiopathic thrombocytopenic purpura indication 32273002 DOID:8924
Psoriasis with arthropathy indication 33339001
Crohn's disease indication 34000006
Tendinitis indication 34840004 DOID:971
Erythema multiforme indication 36715001
Contact dermatitis indication 40275004 DOID:2773
Angioedema indication 41291007 DOID:1558
Humoral hypercalcemia of malignancy indication 47709007
Articular gout indication 48440001 DOID:13189
Edema of larynx indication 51599000
Nephrotic syndrome indication 52254009 DOID:1184
Systemic lupus erythematosus indication 55464009 DOID:9074
Allergic rhinitis indication 61582004
Lรถffler's syndrome indication 64936001 DOID:9503
Pemphigus indication 65172003 DOID:9182
Tenosynovitis indication 67801009 DOID:970
Rheumatoid arthritis indication 69896004 DOID:7148
Transfusion reaction due to serum protein reaction indication 72284000
Acquired thrombocytopenia indication 74576004 DOID:11126
Thyroiditis indication 82119001 DOID:7166
Bursitis indication 84017003 DOID:2965
Autoimmune disease indication 85828009
Infection by larvae of Trichinella spiralis indication 88264003
Congenital hypoplastic anemia indication 88854002 DOID:1339
Acute lymphoid leukemia indication 91857003 DOID:9952
Dermatitis herpetiformis indication 111196000 DOID:8505
Hodgkin's disease indication 118599009
Non-Hodgkin's lymphoma indication 118601006
Mycosis fungoides indication 118618005
Aspiration pneumonitis indication 155597006
Asthma indication 195967001 DOID:2841
Transplanted organ rejection indication 213148006
Adrenogenital disorder indication 267395000 DOID:0050811
Eruption of skin indication 271807003 DOID:0050486
Disorder of eye indication 371405004 DOID:5614
Primary adrenocortical insufficiency indication 373662000
Adrenal cortical hypofunction indication 386584007 DOID:10493
Erythroderma indication 399992009
Autoimmune hemolytic anemia indication 413603009 DOID:718
Synovitis indication 416209007 DOID:2703
Post traumatic osteoarthritis indication 699262001
Erythroblastic Anemia indication
Diagnostic Test for Cushing's Syndrome indication
Transfusion Reaction Urticaria indication
Systemic Dermatomyositis indication
Synovitis due to Osteoarthritis indication
Respiratory distress syndrome in the newborn off-label use 46775006
Neonatal Bronchopulmonary Dysplasia off-label use
Mycosis contraindication 3218000 DOID:1564
Ocular hypertension contraindication 4210003 DOID:9282
Inactive tuberculosis contraindication 11999007
Peptic ulcer contraindication 13200003 DOID:750
Measles contraindication 14189004 DOID:8622
Esophagitis contraindication 16761005 DOID:11963
Mood swings contraindication 18963009
Cirrhosis of liver contraindication 19943007 DOID:5082
Glaucoma contraindication 23986001 DOID:1686
Abscess of intestine contraindication 24557004
Hypertensive disorder contraindication 38341003 DOID:10763
Infectious disease contraindication 40733004
Hypothyroidism contraindication 40930008 DOID:1459
Hypokalemia contraindication 43339004
Chronic heart failure contraindication 48447003
Duodenal ulcer disease contraindication 51868009 DOID:1724
Osteoporosis contraindication 64859006 DOID:11476
Psychotic disorder contraindication 69322001
Diabetes mellitus contraindication 73211009 DOID:9351
Hypopituitarism contraindication 74728003 DOID:9406
Hyperglycemia contraindication 80394007 DOID:4195
Kidney disease contraindication 90708001 DOID:557
Bilateral cataracts contraindication 95722004
Eye infection contraindication 128351009
Disorder of muscle contraindication 129565002 DOID:423
Anastomosis of intestine contraindication 235407009
Diverticulitis of gastrointestinal tract contraindication 271366000
Varicella-zoster virus infection contraindication 309465005
Viral eye infection contraindication 312132001
Gastric ulcer contraindication 397825006 DOID:10808
Exposure to varicella contraindication 444453009




๐Ÿถ Veterinary Drug Use

None

๐Ÿถ Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.23 acidic
pKa2 12.94 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST CHEMBL CHEMBL
Glucocorticoid receptor Transcription factor Kd 6.72 CHEMBL

External reference:

IDSource
D00978 KEGG_DRUG
4017945 VUID
N0000146295 NUI
4017941 VANDF
4017945 VANDF
CHEBI:31677 CHEBI
CHEMBL3989663 ChEMBL_ID
CHEMBL1200495 ChEMBL_ID
DB14545 DRUGBANK_ID
C007133 MESH_SUPPLEMENTAL_RECORD_UI
16623 PUBCHEM_CID
DB00741 DRUGBANK_ID
21651 RXNORM
20708 MMSL
2500 MMSL
41706 MMSL
4837 MMSL
4843 MMSL
73114 MMSL
d00254 MMSL
002147 NDDF
002152 NDDF
005251 NDDF
109066000 SNOMEDCT_US
16602005 SNOMEDCT_US
396458002 SNOMEDCT_US
56423005 SNOMEDCT_US
C0056387 UMLSCUI
C0020268 UMLSCUI
83784-20-7 SECONDARY_CAS_RN
5754 PUBCHEM_CID
38 INN_ID
D006854 MESH_DESCRIPTOR_UI
50LQB69S1Z UNII
CHEBI:17650 CHEBI
50LQB69S1Z INXIGHT DRUGS

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Solu-Cortef HUMAN PRESCRIPTION DRUG LABEL 1 0009-0005 INJECTION, POWDER, FOR SOLUTION 1000 mg INTRAMUSCULAR NDA 22 sections
Solu-Cortef HUMAN PRESCRIPTION DRUG LABEL 1 0009-0011 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR NDA 22 sections
Solu-Cortef HUMAN PRESCRIPTION DRUG LABEL 1 0009-0013 INJECTION, POWDER, FOR SOLUTION 250 mg INTRAMUSCULAR NDA 22 sections
Solu-Cortef HUMAN PRESCRIPTION DRUG LABEL 1 0009-0016 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR NDA 22 sections
Solu-Cortef HUMAN PRESCRIPTION DRUG LABEL 1 0009-0825 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR NDA 22 sections
SOLU-CORTEF HUMAN PRESCRIPTION DRUG LABEL 1 51662-1261 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR NDA 13 sections
SOLU-CORTEF HUMAN PRESCRIPTION DRUG LABEL 1 51662-1262 INJECTION, POWDER, FOR SOLUTION 250 mg INTRAMUSCULAR NDA 13 sections
Solu-Cortef HUMAN PRESCRIPTION DRUG LABEL 1 55154-3942 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR NDA 22 sections
Hydrocortisone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 60505-6411 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR ANDA 21 sections
Hydrocortisone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 69097-004 INJECTION 100 mg INTRAMUSCULAR ANDA 11 sections
Hydrocortisone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 70710-1907 INJECTION 100 mg INTRAMUSCULAR ANDA 12 sections
Hydrocortisone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 70771-1966 INJECTION 100 mg INTRAMUSCULAR ANDA 1 sections
Solu-Cortef HUMAN PRESCRIPTION DRUG LABEL 1 84549-011 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR NDA 22 sections