calcium phosphate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4441 7758-87-4

Description:

MoleculeDescription

Synonyms:

  • calcium phosphate
  • tribasic calcium phosphate
  • tricalcium phosphate
refers to unspecified salt; see other calcium phosphates
  • Molecular weight: 310.17
  • Formula: Ca3O8P2
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 86.25
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Atrioventricular conduction time shortened 18.81 15.37 3 4400 21 50600700
Blood electrolytes increased 17.77 15.37 3 4400 31 50600690
Elliptocytosis 17.36 15.37 3 4400 36 50600685
Product dose omission issue 16.61 15.37 44 4359 183794 50416927
Rectal lesion 16.50 15.37 3 4400 49 50600672
Diarrhoea 15.78 15.37 96 4307 588380 50012341

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Regurgitation 47.81 19.90 12 1866 1295 29571354
Dyspepsia 46.56 19.90 27 1851 30098 29542551
Oropharyngeal discomfort 35.57 19.90 11 1867 2545 29570104
Vitamin B12 deficiency 32.90 19.90 11 1867 3260 29569389
Eructation 30.72 19.90 11 1867 3995 29568654

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Regurgitation 35.22 15.32 11 5107 2098 64491516
Dyspepsia 32.79 15.32 36 5082 80276 64413338
Vitamin B12 deficiency 31.64 15.32 13 5105 5459 64488155
Oropharyngeal discomfort 25.27 15.32 11 5107 5324 64488290
Eructation 22.35 15.32 12 5106 9179 64484435
Atrioventricular conduction time shortened 19.09 15.32 3 5115 21 64493593
Elliptocytosis 17.63 15.32 3 5115 36 64493578
Product dose omission issue 17.57 15.32 44 5074 194703 64298911
Blood electrolytes increased 15.76 15.32 3 5115 70 64493544

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A12AA01 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
CALCIUM
Calcium
MeSH PA D001672 Biocompatible Materials

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Pregnancy, function indication 289908002
Breastfeeding (mother) indication 413712001
Prevention of Fetal Neural Tube Defects during Pregnancy off-label use
Poisoning by digitalis glycoside contraindication 12876009
Peptic ulcer contraindication 13200003 DOID:750
Constipation contraindication 14760008 DOID:2089
Hyperphosphatemia contraindication 20165001 DOID:0050459
Gastroenteritis contraindication 25374005 DOID:2326
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Depressive disorder contraindication 35489007
Hemosiderosis contraindication 39011001 DOID:12119
Mental handicap contraindication 47437004
Systemic lupus erythematosus contraindication 55464009 DOID:9074
Schizophrenia contraindication 58214004 DOID:5419
Hemolytic anemia contraindication 61261009 DOID:583
Ulcerative colitis contraindication 64766004 DOID:8577
Hypercalcemia contraindication 66931009 DOID:12678
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Diabetes mellitus contraindication 73211009 DOID:9351
Autoimmune disease contraindication 85828009
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Neoplasm of prostate contraindication 126906006 DOID:10283
Disease of liver contraindication 235856003 DOID:409
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Diverticular disease contraindication 397881000
Hemochromatosis contraindication 399187006 DOID:2352
Repeated Blood Transfusions contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019973 VUID
N0000148058 NUI
1306-06-5 SECONDARY_CAS_RN
4019973 VANDF
4020044 VANDF
C0006711 UMLSCUI
CHEBI:9679 CHEBI
CHEMBL2107567 ChEMBL_ID
CHEMBL2218916 ChEMBL_ID
CHEMBL2106566 ChEMBL_ID
DB11348 DRUGBANK_ID
C020243 MESH_SUPPLEMENTAL_RECORD_UI
C018392 MESH_SUPPLEMENTAL_RECORD_UI
24456 PUBCHEM_CID
1919 RXNORM
4327 MMSL
4328 MMSL
NOCODE MMSL
d03803 MMSL
005047 NDDF
419939009 SNOMEDCT_US
44044007 SNOMEDCT_US
91D9GV0Z28 UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Prenaissance HUMAN PRESCRIPTION DRUG LABEL 9 42192-341 CAPSULE, LIQUID FILLED 160 mg ORAL UNAPPROVED DRUG OTHER 10 sections
Dairy Allergen Mix HUMAN OTC DRUG LABEL 38 43742-1277 LIQUID 6 [hp_C] ORAL unapproved drug other 9 sections
CS Bone HUMAN OTC DRUG LABEL 11 57955-0211 LIQUID 10 [hp_X] ORAL unapproved homeopathic 9 sections
Exoden Sensitive HUMAN OTC DRUG LABEL 2 70602-006 PASTE 19 g TOPICAL unapproved drug other 8 sections
KUNDAL Sensitive Dental Care Tooth (Apple Chamomile Mint) HUMAN OTC DRUG LABEL 1 74773-0040 PASTE 17 g DENTAL unapproved drug other 7 sections
DIO Enamel Coating Pen Pro Tooth HUMAN OTC DRUG LABEL 3 75902-6001 PASTE, DENTIFRICE 20 g DENTAL unapproved drug other 7 sections