cobamamide Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4404 13870-90-1

Description:

MoleculeDescription

Synonyms:

  • cobamamide
  • adenosylcobalamin
  • cobalamin coenzyme
  • Vitamin B12 coenzyme
  • Molecular weight: 1579.61
  • Formula: C72H100CoN18O17P
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 608.02
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC B03BA04 BLOOD AND BLOOD FORMING ORGANS
ANTIANEMIC PREPARATIONS
VITAMIN B12 AND FOLIC ACID
Vitamin B12 (cyanocobalamin and analogues)

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Prevention of Vitamin B12 Deficiency indication
Hypokalemia contraindication 43339004
Gastrectomy contraindication 53442002
Leber's optic atrophy contraindication 58610003 DOID:705
Atrophic gastritis contraindication 84568007 DOID:8929

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D00042 KEGG_DRUG
C0056039 UMLSCUI
NOCODE MMSL
21373 RXNORM
259509008 SNOMEDCT_US
004345 NDDF
F0R1QK73KB UNII
1915 INN_ID
B1Z PDB_CHEM_ID
DB11191 DRUGBANK_ID
CHEBI:18408 CHEBI
CHEMBL3833359 ChEMBL_ID
6474320 PUBCHEM_CID
C000913 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
EnLyte Extra-LN HUMAN PRESCRIPTION DRUG LABEL 2 64661-117 CAPSULE 25 ug ORAL unapproved drug other 12 sections
EnBrace HR HUMAN PRESCRIPTION DRUG LABEL 5 64661-650 CAPSULE, DELAYED RELEASE PELLETS 50 ug ORAL UNAPPROVED DRUG OTHER 12 sections
EnLyte HUMAN PRESCRIPTION DRUG LABEL 7 64661-711 CAPSULE, DELAYED RELEASE PELLETS 50 ug ORAL unapproved drug other 11 sections