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carisbamate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| tranquillizers, propanediol and pentanediol derivatives | 4400 | 194085-75-1 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
experimental anticonvulsant and neuromodulator
|
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BA (Bioavailability) | 94 % |
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2B,AXL,BRAF,BTK,CAMK2D,CDK5,CDK9,EIF2AK3,ERBB2,GRK2,ITK,MAPK7,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIK3CG,PRKDC,TEK | 20 | |||
| kinase-selectivity-class | AXL,BRAF,CDK9,DDR1,EIF2AK3,EPHB4,GRK2,MAPK7,PDK4,PIK3CD,SIK2,STK33,TEK | 13 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | N03AX19 | NERVOUS SYSTEM ANTIEPILEPTICS ANTIEPILEPTICS Other antiepileptics |
| CHEBI has role | CHEBI:35623 | anticonvulsant |
Related Drugs by ATC class:
N03AX Other antiepileptics 18 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 12.95 | acidic |
| pKa2 | 13.71 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D06573 | KEGG_DRUG |
| C1871983 | UMLSCUI |
| CHEBI:135966 | CHEBI |
| CHEMBL2087003 | ChEMBL_ID |
| DB12338 | DRUGBANK_ID |
| C518914 | MESH_SUPPLEMENTAL_RECORD_UI |
| 8816 | INN_ID |
| P7725I9V3Z | UNII |
| 6918474 | PUBCHEM_CID |
Pharmaceutical products:
None