clofenotane 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4396 50-29-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • dicophane
  • clofenotane
  • chlorophenothane
  • chlorphenothan
  • clofenotan
synthetic insecticide used to combat malaria, typhus, and the other insect-borne human diseases
  • Molecular weight: 354.48
  • Formula: C14H9Cl5
  • CLOGP: 6.76
  • LIPINSKI: 1
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS: -8
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P03AB01 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES
Chlorine containing products
ATC P03AB51 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES, INSECTICIDES AND REPELLENTS
ECTOPARASITICIDES, INCL. SCABICIDES
Chlorine containing products
CHEBI has role CHEBI:39412 bridged diphenyl acaricides
CHEBI has role CHEBI:50903 carcinogen
CHEBI has role CHEBI:77853 persistent organic pollutants
CHEBI has role CHEBI:138015 endocrine disruptors

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Androgen receptor Transcription factor IC50 4.74 CHEMBL

External reference:

IDSource
D07367 KEGG_DRUG
C0011041 UMLSCUI
CHEBI:16130 CHEBI
CHEMBL416898 ChEMBL_ID
DB13424 DRUGBANK_ID
2202 INN_ID
CIW5S16655 UNII
3036 PUBCHEM_CID
002996 NDDF
6WT PDB_CHEM_ID

Pharmaceutical products:

None