chiniofon 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4362 8002-90-2

Description:

MoleculeDescription

Synonyms:

  • chiniofon
The 8-hydroxy derivatives inhibit various enzymes and their halogenated derivatives, though neurotoxic, are used as topical anti-infective agents, among other uses.
  • Molecular weight: 435.12
  • Formula: C10H7INNaO7S
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 87.49
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC P01AX01 ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
ANTIPROTOZOALS
AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES
Other agents against amoebiasis and other protozoal diseases

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Catechol O-methyltransferase Enzyme IC50 5.15 CHEMBL

External reference:

IDSource
D07438 KEGG_DRUG
C0008129 UMLSCUI
CHEMBL2104146 ChEMBL_ID
CHEMBL1788402 ChEMBL_ID
DB13379 DRUGBANK_ID
385 INN_ID
98F8Y85B6W UNII
11043 PUBCHEM_CID
002954 NDDF
111121001 SNOMEDCT_US
D006912 MESH_DESCRIPTOR_UI

Pharmaceutical products:

None