lasofoxifene 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antiestrogens or estrogen receptor modulators, clomifene and tamoxifen derivatives 4308 180916-16-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • lasofoxifene
  • lasofoxifene tartrate
  • fablyn
  • CP-336156
  • CP-336,156
a SERM whose biological actions are largely mediated through binding to estrogen receptors, this binding results in the activation of some estrogenic pathways and a blockade of others, Lasofoxifene produces tissue and cell-specific effects in estrogen-responsive tissues
  • Molecular weight: 413.56
  • Formula: C28H31NO2
  • CLOGP: 6.71
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 32.70
  • ALOGS: -6.02
  • ROTB: 6

Drug dosage:

DoseUnitRoute
0.50 mg O

ADMET properties:

None

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

None

lasofoxifene