| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4290 | 7487-88-9 |
| Molecule | Description |
|---|---|
|
Synonyms:
|
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)
|
| Dose | Unit | Route |
|---|---|---|
| 7 | g | O |
| 3 | g | O |
None
| Date | Agency | Company | Orphan |
|---|---|---|---|
| Oct. 6, 1981 | FDA | BAXTER HLTHCARE | |
| Jan. 22, 2021 | PMDA | NIHON PHARMACEUTICAL CO., LTD. |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Premature delivery | 319.89 | 10.26 | 262 | 67238 | 30019 | 63391503 |
| Macular degeneration | 298.37 | 10.26 | 230 | 67270 | 24146 | 63397376 |
| Normal labour | 245.82 | 10.26 | 65 | 67435 | 452 | 63421070 |
| Delivery | 185.65 | 10.26 | 66 | 67434 | 1337 | 63420185 |
| Contraindicated product administered | 170.35 | 10.26 | 17 | 67483 | 217631 | 63203891 |
| Premature baby | 169.48 | 10.26 | 155 | 67345 | 20580 | 63400942 |
| Synovitis | 159.10 | 10.26 | 10 | 67490 | 186908 | 63234614 |
| Systemic lupus erythematosus | 156.71 | 10.26 | 19 | 67481 | 208899 | 63212623 |
| Hypermagnesaemia | 155.99 | 10.26 | 53 | 67447 | 933 | 63420589 |
| Hand deformity | 154.63 | 10.26 | 3 | 67497 | 159454 | 63262068 |
| Treatment failure | 140.08 | 10.26 | 22 | 67478 | 199021 | 63222501 |
| Exposure during pregnancy | 135.45 | 10.26 | 418 | 67082 | 155129 | 63266393 |
| Completed suicide | 129.54 | 10.26 | 6 | 67494 | 145667 | 63275855 |
| Glossodynia | 127.63 | 10.26 | 19 | 67481 | 178857 | 63242665 |
| Drug intolerance | 112.12 | 10.26 | 98 | 67402 | 308563 | 63112959 |
| Pericarditis | 109.13 | 10.26 | 8 | 67492 | 131571 | 63289951 |
| Pulmonary oedema | 107.37 | 10.26 | 202 | 67298 | 54671 | 63366851 |
| Arthropathy | 107.25 | 10.26 | 58 | 67442 | 234734 | 63186788 |
| Product use issue | 102.89 | 10.26 | 53 | 67447 | 220467 | 63201055 |
| Wound | 96.50 | 10.26 | 27 | 67473 | 163236 | 63258286 |
| Joint swelling | 94.60 | 10.26 | 126 | 67374 | 327540 | 63093982 |
| PCO2 increased | 94.46 | 10.26 | 39 | 67461 | 1200 | 63420322 |
| Paraesthesia oral | 93.81 | 10.26 | 109 | 67391 | 19147 | 63402375 |
| Therapeutic product effect decreased | 84.93 | 10.26 | 50 | 67450 | 193137 | 63228385 |
| Blood pH decreased | 80.75 | 10.26 | 44 | 67456 | 2543 | 63418979 |
| Rheumatoid arthritis | 76.95 | 10.26 | 94 | 67406 | 253725 | 63167797 |
| Maternal exposure during pregnancy | 76.69 | 10.26 | 447 | 67053 | 219615 | 63201907 |
| Duodenal ulcer perforation | 76.20 | 10.26 | 4 | 67496 | 87205 | 63334317 |
| Low birth weight baby | 73.81 | 10.26 | 61 | 67439 | 7068 | 63414454 |
| Chronic sinusitis | 71.61 | 10.26 | 78 | 67422 | 12765 | 63408757 |
| Postpartum haemorrhage | 71.16 | 10.26 | 37 | 67463 | 1944 | 63419578 |
| Blood bicarbonate decreased | 70.24 | 10.26 | 42 | 67458 | 2899 | 63418623 |
| Propofol infusion syndrome | 68.42 | 10.26 | 29 | 67471 | 954 | 63420568 |
| Mitochondrial DNA mutation | 68.00 | 10.26 | 23 | 67477 | 399 | 63421123 |
| Lower respiratory tract infection | 65.97 | 10.26 | 29 | 67471 | 132278 | 63289244 |
| Diabetes insipidus | 64.03 | 10.26 | 38 | 67462 | 2587 | 63418935 |
| Renal ischaemia | 62.46 | 10.26 | 24 | 67476 | 609 | 63420913 |
| Discomfort | 60.87 | 10.26 | 53 | 67447 | 167321 | 63254201 |
| Folliculitis | 59.09 | 10.26 | 4 | 67496 | 70313 | 63351209 |
| Toxicity to various agents | 58.98 | 10.26 | 108 | 67392 | 247142 | 63174380 |
| Procedural pain | 58.78 | 10.26 | 92 | 67408 | 21477 | 63400045 |
| Drug abuse | 58.46 | 10.26 | 5 | 67495 | 72513 | 63349009 |
| Hepatic enzyme increased | 58.12 | 10.26 | 78 | 67422 | 202250 | 63219272 |
| Alopecia | 57.01 | 10.26 | 177 | 67323 | 337359 | 63084163 |
| Hypersensitivity | 55.66 | 10.26 | 145 | 67355 | 292540 | 63128982 |
| Foetal exposure during pregnancy | 52.07 | 10.26 | 109 | 67391 | 31853 | 63389669 |
| Unevaluable event | 51.23 | 10.26 | 145 | 67355 | 51241 | 63370281 |
| PO2 increased | 48.43 | 10.26 | 22 | 67478 | 857 | 63420665 |
| Cytokine release syndrome | 47.55 | 10.26 | 67 | 67433 | 14247 | 63407275 |
| Arthralgia | 47.52 | 10.26 | 383 | 67117 | 569327 | 62852195 |
| Diarrhoea | 45.64 | 10.26 | 1037 | 66463 | 714329 | 62707193 |
| Intentional product use issue | 44.70 | 10.26 | 42 | 67458 | 127850 | 63293672 |
| Vaginal flatulence | 44.54 | 10.26 | 33 | 67467 | 3260 | 63418262 |
| Irritable bowel syndrome | 44.45 | 10.26 | 16 | 67484 | 82396 | 63339126 |
| Drug hypersensitivity | 44.32 | 10.26 | 175 | 67325 | 310512 | 63111010 |
| Blood gases abnormal | 44.08 | 10.26 | 20 | 67480 | 777 | 63420745 |
| Neonatal intestinal perforation | 41.82 | 10.26 | 9 | 67491 | 21 | 63421501 |
| Abdominal discomfort | 40.71 | 10.26 | 189 | 67311 | 320696 | 63100826 |
| Gene mutation | 40.34 | 10.26 | 24 | 67476 | 1641 | 63419881 |
| Helicobacter infection | 39.37 | 10.26 | 25 | 67475 | 92760 | 63328762 |
| Swelling | 39.34 | 10.26 | 155 | 67345 | 275223 | 63146299 |
| Foetal death | 38.87 | 10.26 | 53 | 67447 | 10927 | 63410595 |
| CSF oligoclonal band present | 38.87 | 10.26 | 15 | 67485 | 385 | 63421137 |
| Pre-eclampsia | 38.43 | 10.26 | 48 | 67452 | 9085 | 63412437 |
| Blood magnesium decreased | 38.36 | 10.26 | 58 | 67442 | 13140 | 63408382 |
| C-reactive protein abnormal | 37.64 | 10.26 | 3 | 67497 | 46093 | 63375429 |
| Ill-defined disorder | 36.12 | 10.26 | 21 | 67479 | 81734 | 63339788 |
| Acute respiratory failure | 36.03 | 10.26 | 99 | 67401 | 34386 | 63387136 |
| Blister | 35.31 | 10.26 | 52 | 67448 | 129762 | 63291760 |
| Hypomagnesaemia | 34.62 | 10.26 | 87 | 67413 | 28650 | 63392872 |
| Intentional overdose | 34.28 | 10.26 | 18 | 67482 | 74134 | 63347388 |
| Muscle spasms | 34.06 | 10.26 | 283 | 67217 | 155867 | 63265655 |
| Proctitis | 33.80 | 10.26 | 35 | 67465 | 5406 | 63416116 |
| Neonatal respiratory distress syndrome | 33.18 | 10.26 | 26 | 67474 | 2792 | 63418730 |
| Deep vein thrombosis | 32.29 | 10.26 | 175 | 67325 | 83625 | 63337897 |
| Colitis | 32.08 | 10.26 | 119 | 67381 | 48409 | 63373113 |
| Impaired healing | 32.08 | 10.26 | 37 | 67463 | 102505 | 63319017 |
| Airway peak pressure increased | 32.05 | 10.26 | 12 | 67488 | 283 | 63421239 |
| Caesarean section | 31.21 | 10.26 | 61 | 67439 | 16971 | 63404551 |
| COVID-19 | 31.06 | 10.26 | 45 | 67455 | 113058 | 63308464 |
| Blood lactic acid increased | 31.03 | 10.26 | 38 | 67462 | 7048 | 63414474 |
| Musculoskeletal stiffness | 30.99 | 10.26 | 97 | 67403 | 184521 | 63237001 |
| Gastrointestinal disorder | 30.67 | 10.26 | 58 | 67442 | 131181 | 63290341 |
| Neuropathy peripheral | 30.36 | 10.26 | 216 | 67284 | 113451 | 63308071 |
| Hypotension | 30.01 | 10.26 | 431 | 67069 | 272173 | 63149349 |
| Device expulsion | 29.55 | 10.26 | 93 | 67407 | 34829 | 63386693 |
| Full blood count decreased | 29.50 | 10.26 | 77 | 67423 | 25947 | 63395575 |
| Blood magnesium increased | 29.39 | 10.26 | 25 | 67475 | 3013 | 63418509 |
| Suicide attempt | 29.34 | 10.26 | 14 | 67486 | 60904 | 63360618 |
| Female genital tract fistula | 29.08 | 10.26 | 38 | 67462 | 7521 | 63414001 |
| Neuromuscular blockade | 28.34 | 10.26 | 11 | 67489 | 287 | 63421235 |
| Pleocytosis | 28.13 | 10.26 | 15 | 67485 | 830 | 63420692 |
| Oxygen saturation abnormal | 28.09 | 10.26 | 26 | 67474 | 3503 | 63418019 |
| Respiratory failure | 28.04 | 10.26 | 195 | 67305 | 101663 | 63319859 |
| Vaginal discharge | 27.55 | 10.26 | 41 | 67459 | 9157 | 63412365 |
| Liver injury | 27.52 | 10.26 | 15 | 67485 | 60505 | 63361017 |
| Maternal exposure during delivery | 27.22 | 10.26 | 18 | 67482 | 1482 | 63420040 |
| Lung hyperinflation | 27.11 | 10.26 | 17 | 67483 | 1278 | 63420244 |
| Radiculopathy | 26.68 | 10.26 | 39 | 67461 | 8572 | 63412950 |
| Apgar score low | 26.33 | 10.26 | 14 | 67486 | 770 | 63420752 |
| Respiratory acidosis | 26.21 | 10.26 | 34 | 67466 | 6681 | 63414841 |
| Device dislocation | 26.07 | 10.26 | 73 | 67427 | 25632 | 63395890 |
| Product dose omission issue | 25.99 | 10.26 | 371 | 67129 | 233942 | 63187580 |
| Condition aggravated | 25.93 | 10.26 | 288 | 67212 | 401929 | 63019593 |
| Neuromuscular block prolonged | 25.01 | 10.26 | 12 | 67488 | 530 | 63420992 |
| Vaginal haemorrhage | 24.93 | 10.26 | 75 | 67425 | 27412 | 63394110 |
| Hypervolaemia | 24.34 | 10.26 | 76 | 67424 | 28337 | 63393185 |
| Urticaria thermal | 24.23 | 10.26 | 11 | 67489 | 428 | 63421094 |
| General physical health deterioration | 24.13 | 10.26 | 121 | 67379 | 201281 | 63220241 |
| Therapy cessation | 23.86 | 10.26 | 79 | 67421 | 30378 | 63391144 |
| Anaemia | 23.74 | 10.26 | 441 | 67059 | 292989 | 63128533 |
| Craniotabes | 23.39 | 10.26 | 4 | 67496 | 0 | 63421522 |
| Dehydration | 22.74 | 10.26 | 283 | 67217 | 173071 | 63248451 |
| HELLP syndrome | 22.60 | 10.26 | 14 | 67486 | 1030 | 63420492 |
| Pneumonia | 22.46 | 10.26 | 640 | 66860 | 456127 | 62965395 |
| PO2 decreased | 22.43 | 10.26 | 16 | 67484 | 1490 | 63420032 |
| Premature labour | 21.96 | 10.26 | 44 | 67456 | 12460 | 63409062 |
| Encephalopathy | 21.71 | 10.26 | 90 | 67410 | 38530 | 63382992 |
| Asthma | 21.41 | 10.26 | 67 | 67433 | 127494 | 63294028 |
| Neonatal gastrointestinal haemorrhage | 21.21 | 10.26 | 5 | 67495 | 20 | 63421502 |
| Infection | 19.99 | 10.26 | 152 | 67348 | 229021 | 63192501 |
| Hypoxia | 19.84 | 10.26 | 120 | 67380 | 59672 | 63361850 |
| Foetal heart rate deceleration abnormality | 19.71 | 10.26 | 10 | 67490 | 499 | 63421023 |
| Sepsis | 19.67 | 10.26 | 249 | 67251 | 152874 | 63268648 |
| Dyspepsia | 19.56 | 10.26 | 180 | 67320 | 102016 | 63319506 |
| Infusion related reaction | 19.51 | 10.26 | 167 | 67333 | 245354 | 63176168 |
| Hypocalcaemia | 19.50 | 10.26 | 76 | 67424 | 31637 | 63389885 |
| Status asthmaticus | 19.26 | 10.26 | 12 | 67488 | 892 | 63420630 |
| Hypercapnia | 18.90 | 10.26 | 26 | 67474 | 5405 | 63416117 |
| Plasma cell myeloma | 18.88 | 10.26 | 82 | 67418 | 35823 | 63385699 |
| Pain | 18.71 | 10.26 | 623 | 66877 | 740005 | 62681517 |
| Constipation | 18.50 | 10.26 | 339 | 67161 | 224604 | 63196918 |
| Pelvic pain | 18.50 | 10.26 | 43 | 67457 | 13476 | 63408046 |
| Administration site erythema | 18.46 | 10.26 | 11 | 67489 | 754 | 63420768 |
| Acute pulmonary oedema | 18.45 | 10.26 | 32 | 67468 | 8126 | 63413396 |
| Neonatal disorder | 18.43 | 10.26 | 10 | 67490 | 573 | 63420949 |
| Nausea | 18.04 | 10.26 | 1094 | 66406 | 853377 | 62568145 |
| Infantile apnoea | 17.79 | 10.26 | 12 | 67488 | 1021 | 63420501 |
| Psoriasis | 17.58 | 10.26 | 155 | 67345 | 86802 | 63334720 |
| Foetal growth restriction | 17.57 | 10.26 | 30 | 67470 | 7523 | 63413999 |
| Hypokalaemia | 17.48 | 10.26 | 178 | 67322 | 103626 | 63317896 |
| Hip arthroplasty | 17.41 | 10.26 | 15 | 67485 | 47631 | 63373891 |
| Left ventricular dysfunction | 17.37 | 10.26 | 39 | 67461 | 11949 | 63409573 |
| Skin discolouration | 17.37 | 10.26 | 83 | 67417 | 37745 | 63383777 |
| Blood potassium decreased | 17.02 | 10.26 | 89 | 67411 | 41937 | 63379585 |
| Intentional product misuse | 16.95 | 10.26 | 24 | 67476 | 60893 | 63360629 |
| Off label use | 16.86 | 10.26 | 568 | 66932 | 673894 | 62747628 |
| Weight increased | 16.67 | 10.26 | 187 | 67313 | 260605 | 63160917 |
| Chills | 16.58 | 10.26 | 189 | 67311 | 113189 | 63308333 |
| Frequent bowel movements | 16.52 | 10.26 | 58 | 67442 | 22964 | 63398558 |
| Loss of personal independence in daily activities | 16.39 | 10.26 | 51 | 67449 | 97239 | 63324283 |
| Dizziness | 16.30 | 10.26 | 584 | 66916 | 429341 | 62992181 |
| Fear | 16.21 | 10.26 | 45 | 67455 | 15721 | 63405801 |
| Delayed fontanelle closure | 16.08 | 10.26 | 4 | 67496 | 21 | 63421501 |
| Rectal haemorrhage | 16.01 | 10.26 | 98 | 67402 | 48932 | 63372590 |
| Atrial fibrillation | 15.98 | 10.26 | 192 | 67308 | 116444 | 63305078 |
| Red blood cell sedimentation rate increased | 15.89 | 10.26 | 14 | 67486 | 43968 | 63377554 |
| Myelosuppression | 15.82 | 10.26 | 3 | 67497 | 23700 | 63397822 |
| Neonatal infection | 15.81 | 10.26 | 6 | 67494 | 147 | 63421375 |
| Nail bed tenderness | 15.73 | 10.26 | 8 | 67492 | 401 | 63421121 |
| C-reactive protein increased | 15.71 | 10.26 | 50 | 67450 | 94657 | 63326865 |
| Intentional self-injury | 15.63 | 10.26 | 4 | 67496 | 25683 | 63395839 |
| Drug interaction | 15.57 | 10.26 | 162 | 67338 | 228969 | 63192553 |
| Osteonecrosis of jaw | 15.54 | 10.26 | 9 | 67491 | 35114 | 63386408 |
| Normal newborn | 15.43 | 10.26 | 30 | 67470 | 8311 | 63413211 |
| Blood calcium decreased | 15.15 | 10.26 | 62 | 67438 | 26389 | 63395133 |
| Flatulence | 15.11 | 10.26 | 75 | 67425 | 34627 | 63386895 |
| Platelet count decreased | 14.98 | 10.26 | 189 | 67311 | 115933 | 63305589 |
| Product compounding quality issue | 14.86 | 10.26 | 4 | 67496 | 30 | 63421492 |
| Nasopharyngitis | 14.84 | 10.26 | 186 | 67314 | 254071 | 63167451 |
| Immune effector cell-associated neurotoxicity syndrome | 14.78 | 10.26 | 15 | 67485 | 2262 | 63419260 |
| Asthenia | 14.76 | 10.26 | 522 | 66978 | 383082 | 63038440 |
| Ventricular extrasystoles | 14.73 | 10.26 | 36 | 67464 | 11651 | 63409871 |
| Laboratory test abnormal | 14.57 | 10.26 | 62 | 67438 | 26850 | 63394672 |
| Therapeutic response decreased | 14.53 | 10.26 | 27 | 67473 | 61498 | 63360024 |
| Haemoglobin decreased | 14.41 | 10.26 | 226 | 67274 | 145259 | 63276263 |
| Clonus | 14.37 | 10.26 | 21 | 67479 | 4615 | 63416907 |
| Pleural effusion | 14.36 | 10.26 | 157 | 67343 | 93053 | 63328469 |
| Vitamin B6 increased | 14.12 | 10.26 | 4 | 67496 | 37 | 63421485 |
| Abdominal distension | 13.86 | 10.26 | 147 | 67353 | 86468 | 63335054 |
| Overdose | 13.85 | 10.26 | 69 | 67431 | 115009 | 63306513 |
| Anaphylactic shock | 13.78 | 10.26 | 4 | 67496 | 23629 | 63397893 |
| Knee arthroplasty | 13.51 | 10.26 | 23 | 67477 | 54183 | 63367339 |
| Electroencephalogram abnormal | 13.42 | 10.26 | 18 | 67482 | 3654 | 63417868 |
| Cystitis-like symptom | 13.39 | 10.26 | 3 | 67497 | 9 | 63421513 |
| Device related sepsis | 13.35 | 10.26 | 19 | 67481 | 4075 | 63417447 |
| Endometritis | 13.32 | 10.26 | 10 | 67490 | 1008 | 63420514 |
| Abdominal pain | 13.25 | 10.26 | 407 | 67093 | 293049 | 63128473 |
| Blood pressure fluctuation | 13.14 | 10.26 | 18 | 67482 | 46299 | 63375223 |
| Bursitis | 13.13 | 10.26 | 12 | 67488 | 37029 | 63384493 |
| Weight decreased | 13.07 | 10.26 | 386 | 67114 | 276412 | 63145110 |
| Feeling abnormal | 13.03 | 10.26 | 226 | 67274 | 148166 | 63273356 |
| Patent ductus arteriosus | 12.81 | 10.26 | 19 | 67481 | 4231 | 63417291 |
| Pulmonary hypertension | 12.63 | 10.26 | 75 | 67425 | 37048 | 63384474 |
| Drug ineffective | 12.44 | 10.26 | 950 | 66550 | 1043815 | 62377707 |
| Intestinal dilatation | 12.39 | 10.26 | 12 | 67488 | 1710 | 63419812 |
| Mobility decreased | 12.21 | 10.26 | 77 | 67423 | 121082 | 63300440 |
| Mental status changes | 12.21 | 10.26 | 78 | 67422 | 39521 | 63382001 |
| Blood albumin decreased | 12.19 | 10.26 | 39 | 67461 | 14727 | 63406795 |
| Osmotic demyelination syndrome | 12.14 | 10.26 | 8 | 67492 | 655 | 63420867 |
| Coma | 12.12 | 10.26 | 32 | 67468 | 64332 | 63357190 |
| Joint range of motion decreased | 12.10 | 10.26 | 10 | 67490 | 32418 | 63389104 |
| Pancreatitis chronic | 11.99 | 10.26 | 14 | 67486 | 2470 | 63419052 |
| Drug reaction with eosinophilia and systemic symptoms | 11.94 | 10.26 | 11 | 67489 | 33825 | 63387697 |
| Emotional distress | 11.88 | 10.26 | 67 | 67433 | 32482 | 63389040 |
| Fall | 11.84 | 10.26 | 520 | 66980 | 391814 | 63029708 |
| Adverse event | 11.68 | 10.26 | 35 | 67465 | 67524 | 63353998 |
| Antinuclear antibody positive | 11.56 | 10.26 | 26 | 67474 | 7973 | 63413549 |
| Interstitial lung disease | 11.49 | 10.26 | 31 | 67469 | 61877 | 63359645 |
| Myasthenia gravis crisis | 11.42 | 10.26 | 7 | 67493 | 505 | 63421017 |
| Inflammation | 11.29 | 10.26 | 47 | 67453 | 82226 | 63339296 |
| Blood culture positive | 11.27 | 10.26 | 19 | 67481 | 4716 | 63416806 |
| Urine output decreased | 11.24 | 10.26 | 32 | 67468 | 11338 | 63410184 |
| Blood pressure systolic increased | 11.02 | 10.26 | 21 | 67479 | 47376 | 63374146 |
| Fibromyalgia | 11.00 | 10.26 | 46 | 67454 | 80374 | 63341148 |
| Fallot's tetralogy | 10.99 | 10.26 | 4 | 67496 | 87 | 63421435 |
| Vulvovaginal swelling | 10.95 | 10.26 | 7 | 67493 | 544 | 63420978 |
| Hypoaesthesia | 10.92 | 10.26 | 245 | 67255 | 168148 | 63253374 |
| Grip strength decreased | 10.92 | 10.26 | 5 | 67495 | 22282 | 63399240 |
| Flushing | 10.90 | 10.26 | 125 | 67375 | 74962 | 63346560 |
| Hepatitis | 10.75 | 10.26 | 16 | 67484 | 39772 | 63381750 |
| Diastolic hypotension | 10.74 | 10.26 | 4 | 67496 | 93 | 63421429 |
| Pulmonary valve incompetence | 10.64 | 10.26 | 10 | 67490 | 1373 | 63420149 |
| Rhabdomyolysis | 10.64 | 10.26 | 19 | 67481 | 43932 | 63377590 |
| Plasma cell myeloma recurrent | 10.61 | 10.26 | 15 | 67485 | 3198 | 63418324 |
| Hypoventilation neonatal | 10.57 | 10.26 | 3 | 67497 | 28 | 63421494 |
| Eclampsia | 10.56 | 10.26 | 6 | 67494 | 376 | 63421146 |
| Vascular resistance systemic decreased | 10.54 | 10.26 | 4 | 67496 | 98 | 63421424 |
| Hypophagia | 10.53 | 10.26 | 63 | 67437 | 31196 | 63390326 |
| Colitis ulcerative | 10.39 | 10.26 | 55 | 67445 | 26036 | 63395486 |
| Lethargy | 10.38 | 10.26 | 98 | 67402 | 55909 | 63365613 |
| Diabetes mellitus | 10.32 | 10.26 | 28 | 67472 | 55782 | 63365740 |
| Obesity | 10.27 | 10.26 | 10 | 67490 | 29942 | 63391580 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Premature baby | 106.20 | 10.59 | 122 | 40210 | 19511 | 34897088 |
| Adrenal suppression | 85.28 | 10.59 | 31 | 40301 | 616 | 34915983 |
| Drug abuse | 80.10 | 10.59 | 10 | 40322 | 99086 | 34817513 |
| Completed suicide | 76.74 | 10.59 | 11 | 40321 | 98157 | 34818442 |
| Cytokine release syndrome | 74.92 | 10.59 | 111 | 40221 | 22766 | 34893833 |
| Gingival disorder | 60.45 | 10.59 | 31 | 40301 | 1456 | 34915143 |
| Toxicity to various agents | 59.41 | 10.59 | 87 | 40245 | 200275 | 34716324 |
| Off label use | 55.25 | 10.59 | 273 | 40059 | 419251 | 34497348 |
| Low birth weight baby | 47.66 | 10.59 | 52 | 40280 | 7853 | 34908746 |
| Skin irritation | 45.13 | 10.59 | 43 | 40289 | 5534 | 34911065 |
| Tachycardia foetal | 39.92 | 10.59 | 15 | 40317 | 328 | 34916271 |
| Drug interaction | 39.07 | 10.59 | 132 | 40200 | 225814 | 34690785 |
| Immune effector cell-associated neurotoxicity syndrome | 38.67 | 10.59 | 33 | 40299 | 3680 | 34912919 |
| Intentional product misuse | 38.35 | 10.59 | 4 | 40328 | 45607 | 34870992 |
| Product use in unapproved indication | 35.79 | 10.59 | 50 | 40282 | 117449 | 34799150 |
| Oral disorder | 32.94 | 10.59 | 32 | 40300 | 4217 | 34912382 |
| Drug ineffective | 32.92 | 10.59 | 353 | 39979 | 456398 | 34460201 |
| Plasma cell myeloma | 32.84 | 10.59 | 115 | 40217 | 41922 | 34874677 |
| Foetal exposure during pregnancy | 30.43 | 10.59 | 105 | 40227 | 37996 | 34878603 |
| Unevaluable event | 29.77 | 10.59 | 94 | 40238 | 32496 | 34884103 |
| Apgar score low | 28.88 | 10.59 | 16 | 40316 | 879 | 34915720 |
| Respiratory disorder | 28.08 | 10.59 | 66 | 40266 | 19198 | 34897401 |
| Pneumonia | 27.83 | 10.59 | 579 | 39753 | 362048 | 34554551 |
| General physical health deterioration | 27.19 | 10.59 | 68 | 40264 | 128201 | 34788398 |
| Blood potassium decreased | 26.80 | 10.59 | 62 | 40270 | 17853 | 34898746 |
| Foetal distress syndrome | 25.82 | 10.59 | 16 | 40316 | 1084 | 34915515 |
| Sleep disorder due to a general medical condition | 25.82 | 10.59 | 31 | 40301 | 5190 | 34911409 |
| Diarrhoea | 24.72 | 10.59 | 606 | 39726 | 389306 | 34527293 |
| Overdose | 24.60 | 10.59 | 42 | 40290 | 91017 | 34825582 |
| Fatigue | 24.37 | 10.59 | 579 | 39753 | 370074 | 34546525 |
| Suicide attempt | 23.31 | 10.59 | 8 | 40324 | 39108 | 34877491 |
| Intentional overdose | 22.67 | 10.59 | 11 | 40321 | 43663 | 34872936 |
| Asthenia | 22.65 | 10.59 | 403 | 39929 | 244848 | 34671751 |
| Hypermagnesaemia | 22.12 | 10.59 | 9 | 40323 | 245 | 34916354 |
| Burkholderia test positive | 21.81 | 10.59 | 14 | 40318 | 1009 | 34915590 |
| Small intestinal obstruction | 21.74 | 10.59 | 51 | 40281 | 14815 | 34901784 |
| Laboratory test abnormal | 21.62 | 10.59 | 62 | 40270 | 20329 | 34896270 |
| Fall | 20.76 | 10.59 | 339 | 39993 | 202546 | 34714053 |
| Hypoxia | 19.86 | 10.59 | 120 | 40212 | 54975 | 34861624 |
| Anhedonia | 19.56 | 10.59 | 33 | 40299 | 7552 | 34909047 |
| Product use issue | 19.13 | 10.59 | 27 | 40305 | 63189 | 34853410 |
| White blood cell count decreased | 19.13 | 10.59 | 181 | 40151 | 95264 | 34821335 |
| Respiratory tract infection bacterial | 18.89 | 10.59 | 16 | 40316 | 1766 | 34914833 |
| Fear | 18.78 | 10.59 | 39 | 40293 | 10437 | 34906162 |
| Intentional product use issue | 18.65 | 10.59 | 25 | 40307 | 59791 | 34856808 |
| Full blood count decreased | 18.22 | 10.59 | 54 | 40278 | 18034 | 34898565 |
| Injury | 17.38 | 10.59 | 58 | 40274 | 20629 | 34895970 |
| Adrenal insufficiency | 17.17 | 10.59 | 45 | 40287 | 14002 | 34902597 |
| Lip swelling | 17.15 | 10.59 | 49 | 40283 | 16031 | 34900568 |
| Dehydration | 17.15 | 10.59 | 227 | 40105 | 129742 | 34786857 |
| Constipation | 16.75 | 10.59 | 236 | 40096 | 136746 | 34779853 |
| Complication of device removal | 16.55 | 10.59 | 5 | 40327 | 54 | 34916545 |
| Mental status changes | 16.39 | 10.59 | 87 | 40245 | 37996 | 34878603 |
| Viral infection | 16.24 | 10.59 | 51 | 40281 | 17572 | 34899027 |
| Bradycardia foetal | 16.00 | 10.59 | 8 | 40324 | 356 | 34916243 |
| Foetal heart rate deceleration abnormality | 15.96 | 10.59 | 9 | 40323 | 512 | 34916087 |
| Bronchiectasis | 15.86 | 10.59 | 35 | 40297 | 9766 | 34906833 |
| Product contamination | 15.69 | 10.59 | 10 | 40322 | 712 | 34915887 |
| Sepsis | 15.45 | 10.59 | 274 | 40058 | 166287 | 34750312 |
| Platelet count decreased | 15.34 | 10.59 | 208 | 40124 | 119509 | 34797090 |
| Rhabdomyolysis | 15.33 | 10.59 | 35 | 40297 | 68128 | 34848471 |
| Rheumatoid arthritis | 15.25 | 10.59 | 13 | 40319 | 38225 | 34878374 |
| Condition aggravated | 15.22 | 10.59 | 145 | 40187 | 192051 | 34724548 |
| Treatment failure | 15.09 | 10.59 | 19 | 40313 | 46678 | 34869921 |
| Caesarean section | 14.40 | 10.59 | 15 | 40317 | 2149 | 34914450 |
| Drug resistance | 14.28 | 10.59 | 6 | 40326 | 25921 | 34890678 |
| Respiratory tract infection viral | 14.21 | 10.59 | 16 | 40316 | 2501 | 34914098 |
| Renal injury | 13.82 | 10.59 | 36 | 40296 | 11159 | 34905440 |
| Acute respiratory failure | 13.55 | 10.59 | 71 | 40261 | 30857 | 34885742 |
| Behaviour disorder | 13.52 | 10.59 | 22 | 40310 | 4888 | 34911711 |
| Contraindicated product administered | 13.49 | 10.59 | 4 | 40328 | 21477 | 34895122 |
| Splenic vein thrombosis | 13.38 | 10.59 | 8 | 40324 | 508 | 34916091 |
| Coma | 13.34 | 10.59 | 20 | 40312 | 45658 | 34870941 |
| Adverse drug reaction | 12.61 | 10.59 | 67 | 40265 | 29275 | 34887324 |
| Neuropathy peripheral | 12.50 | 10.59 | 149 | 40183 | 83114 | 34833485 |
| Agranulocytosis | 12.36 | 10.59 | 6 | 40326 | 23815 | 34892784 |
| Back pain | 12.25 | 10.59 | 203 | 40129 | 121586 | 34795013 |
| Pantoea agglomerans infection | 12.17 | 10.59 | 4 | 40328 | 58 | 34916541 |
| Hypervolaemia | 12.15 | 10.59 | 50 | 40282 | 19659 | 34896940 |
| Patent ductus arteriosus | 12.03 | 10.59 | 17 | 40315 | 3337 | 34913262 |
| Mixed dementia | 11.89 | 10.59 | 6 | 40326 | 272 | 34916327 |
| Oesophagitis | 11.88 | 10.59 | 38 | 40294 | 13223 | 34903376 |
| Anorgasmia | 11.87 | 10.59 | 9 | 40323 | 848 | 34915751 |
| Product dose omission issue | 11.84 | 10.59 | 199 | 40133 | 119512 | 34797087 |
| Blood magnesium decreased | 11.62 | 10.59 | 24 | 40308 | 6399 | 34910200 |
| Metabolic encephalopathy | 11.50 | 10.59 | 19 | 40313 | 4273 | 34912326 |
| Ureteric stenosis | 11.33 | 10.59 | 10 | 40322 | 1166 | 34915433 |
| Maternal drugs affecting foetus | 11.23 | 10.59 | 18 | 40314 | 3947 | 34912652 |
| Intraventricular haemorrhage neonatal | 11.22 | 10.59 | 6 | 40326 | 307 | 34916292 |
| Catheter site related reaction | 11.13 | 10.59 | 6 | 40326 | 312 | 34916287 |
| Apnoea | 11.01 | 10.59 | 24 | 40308 | 6640 | 34909959 |
| Hepatocellular injury | 10.92 | 10.59 | 6 | 40326 | 22205 | 34894394 |
| Transverse presentation | 10.84 | 10.59 | 4 | 40328 | 83 | 34916516 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Completed suicide | 200.14 | 9.67 | 16 | 84484 | 245751 | 79414137 |
| Premature delivery | 177.94 | 9.67 | 168 | 84332 | 23299 | 79636589 |
| Exposure during pregnancy | 145.25 | 9.67 | 327 | 84173 | 100805 | 79559083 |
| Synovitis | 137.55 | 9.67 | 5 | 84495 | 150729 | 79509159 |
| Toxicity to various agents | 123.93 | 9.67 | 159 | 84341 | 421381 | 79238507 |
| Drug abuse | 123.39 | 9.67 | 14 | 84486 | 162677 | 79497211 |
| Cytokine release syndrome | 116.36 | 9.67 | 166 | 84334 | 35832 | 79624056 |
| Contraindicated product administered | 108.97 | 9.67 | 18 | 84482 | 157520 | 79502368 |
| Hypermagnesaemia | 108.18 | 9.67 | 43 | 84457 | 1201 | 79658687 |
| Drug intolerance | 101.18 | 9.67 | 79 | 84421 | 264040 | 79395848 |
| Hand deformity | 92.92 | 9.67 | 4 | 84496 | 103915 | 79555973 |
| Macular degeneration | 89.73 | 9.67 | 83 | 84417 | 11213 | 79648675 |
| Treatment failure | 86.71 | 9.67 | 36 | 84464 | 170450 | 79489438 |
| PCO2 increased | 82.81 | 9.67 | 40 | 84460 | 1800 | 79658088 |
| Systemic lupus erythematosus | 81.25 | 9.67 | 15 | 84485 | 121134 | 79538754 |
| Paraesthesia oral | 80.75 | 9.67 | 104 | 84396 | 20367 | 79639521 |
| Joint swelling | 77.61 | 9.67 | 116 | 84384 | 288530 | 79371358 |
| Product use issue | 71.57 | 9.67 | 70 | 84430 | 209752 | 79450136 |
| Blood pH decreased | 67.92 | 9.67 | 49 | 84451 | 4662 | 79655226 |
| Product use in unapproved indication | 67.89 | 9.67 | 100 | 84400 | 250259 | 79409629 |
| Mitochondrial DNA mutation | 67.50 | 9.67 | 23 | 84477 | 410 | 79659478 |
| Arthropathy | 65.27 | 9.67 | 55 | 84445 | 177056 | 79482832 |
| Chronic sinusitis | 64.09 | 9.67 | 74 | 84426 | 12952 | 79646936 |
| Procedural pain | 63.90 | 9.67 | 99 | 84401 | 22985 | 79636903 |
| Rheumatoid arthritis | 60.79 | 9.67 | 79 | 84421 | 208391 | 79451497 |
| Diabetes insipidus | 58.97 | 9.67 | 47 | 84453 | 5190 | 79654698 |
| Unevaluable event | 58.85 | 9.67 | 160 | 84340 | 55425 | 79604463 |
| Intentional product use issue | 58.85 | 9.67 | 45 | 84455 | 152067 | 79507821 |
| Pericarditis | 58.06 | 9.67 | 19 | 84481 | 104217 | 79555671 |
| Drug interaction | 57.21 | 9.67 | 236 | 84264 | 414947 | 79244941 |
| Maternal exposure during pregnancy | 54.38 | 9.67 | 287 | 84213 | 136251 | 79523637 |
| Glossodynia | 53.87 | 9.67 | 21 | 84479 | 103316 | 79556572 |
| Propofol infusion syndrome | 51.87 | 9.67 | 30 | 84470 | 1953 | 79657935 |
| Intentional product misuse | 51.86 | 9.67 | 18 | 84482 | 95147 | 79564741 |
| Blood bicarbonate decreased | 50.93 | 9.67 | 43 | 84457 | 5148 | 79654740 |
| Foetal death | 50.57 | 9.67 | 52 | 84448 | 7992 | 79651896 |
| Vaginal flatulence | 49.52 | 9.67 | 32 | 84468 | 2543 | 79657345 |
| Duodenal ulcer perforation | 49.43 | 9.67 | 6 | 84494 | 66205 | 79593683 |
| Hepatic enzyme increased | 49.42 | 9.67 | 73 | 84427 | 182537 | 79477351 |
| Renal ischaemia | 48.51 | 9.67 | 24 | 84476 | 1138 | 79658750 |
| Helicobacter infection | 48.11 | 9.67 | 8 | 84492 | 69696 | 79590192 |
| Therapeutic product effect decreased | 47.86 | 9.67 | 62 | 84438 | 163801 | 79496087 |
| Pulmonary oedema | 47.15 | 9.67 | 202 | 84298 | 88052 | 79571836 |
| General physical health deterioration | 46.87 | 9.67 | 143 | 84357 | 275095 | 79384793 |
| Acute respiratory failure | 46.57 | 9.67 | 154 | 84346 | 59387 | 79600501 |
| Pneumonia | 46.36 | 9.67 | 968 | 83532 | 659278 | 79000610 |
| Pre-eclampsia | 45.14 | 9.67 | 46 | 84454 | 6995 | 79652893 |
| Off label use | 44.64 | 9.67 | 685 | 83815 | 906530 | 78753358 |
| Blood magnesium decreased | 44.57 | 9.67 | 70 | 84430 | 16442 | 79643446 |
| Intentional overdose | 44.06 | 9.67 | 29 | 84471 | 105931 | 79553957 |
| Arthralgia | 43.48 | 9.67 | 392 | 84108 | 571411 | 79088477 |
| Diarrhoea | 42.62 | 9.67 | 1227 | 83273 | 879262 | 78780626 |
| Hypoxia | 41.09 | 9.67 | 217 | 84283 | 103026 | 79556862 |
| Device expulsion | 40.93 | 9.67 | 87 | 84413 | 25774 | 79634114 |
| Immune effector cell-associated neurotoxicity syndrome | 40.80 | 9.67 | 40 | 84460 | 5808 | 79654080 |
| Hypomagnesaemia | 40.01 | 9.67 | 125 | 84375 | 46786 | 79613102 |
| Muscle injury | 39.94 | 9.67 | 3 | 84497 | 48558 | 79611330 |
| Suicide attempt | 39.81 | 9.67 | 19 | 84481 | 82913 | 79576975 |
| Dehydration | 39.76 | 9.67 | 420 | 84080 | 247767 | 79412121 |
| Hypervolaemia | 39.45 | 9.67 | 117 | 84383 | 42573 | 79617315 |
| Folliculitis | 39.02 | 9.67 | 6 | 84494 | 55374 | 79604514 |
| Lower respiratory tract infection | 38.66 | 9.67 | 48 | 84452 | 129172 | 79530716 |
| Wound | 38.18 | 9.67 | 40 | 84460 | 116139 | 79543749 |
| CSF oligoclonal band present | 38.18 | 9.67 | 15 | 84485 | 406 | 79659482 |
| Blood potassium decreased | 37.90 | 9.67 | 122 | 84378 | 46390 | 79613498 |
| Plasma cell myeloma | 37.49 | 9.67 | 133 | 84367 | 53126 | 79606762 |
| Deep vein thrombosis | 36.96 | 9.67 | 237 | 84263 | 120682 | 79539206 |
| Blood gases abnormal | 36.70 | 9.67 | 20 | 84480 | 1160 | 79658728 |
| PO2 increased | 36.24 | 9.67 | 22 | 84478 | 1566 | 79658322 |
| Fear | 36 | 9.67 | 75 | 84425 | 21911 | 79637977 |
| Mental status changes | 35.56 | 9.67 | 153 | 84347 | 66806 | 79593082 |
| Hypotension | 34.32 | 9.67 | 656 | 83844 | 439661 | 79220227 |
| Therapeutic response decreased | 34.16 | 9.67 | 14 | 84486 | 66839 | 79593049 |
| Overdose | 34.05 | 9.67 | 92 | 84408 | 184114 | 79475774 |
| Respiratory failure | 33.73 | 9.67 | 316 | 84184 | 180595 | 79479293 |
| Product dose omission issue | 32.92 | 9.67 | 404 | 84096 | 247133 | 79412755 |
| Female genital tract fistula | 32.91 | 9.67 | 36 | 84464 | 5939 | 79653949 |
| Vaginal discharge | 32.75 | 9.67 | 40 | 84460 | 7423 | 79652465 |
| Sepsis | 31.73 | 9.67 | 430 | 84070 | 268998 | 79390890 |
| Hepatocellular injury | 31.67 | 9.67 | 6 | 84494 | 47587 | 79612301 |
| Condition aggravated | 31.65 | 9.67 | 359 | 84141 | 500765 | 79159123 |
| Coma | 31.58 | 9.67 | 36 | 84464 | 100613 | 79559275 |
| Respiratory acidosis | 30.95 | 9.67 | 48 | 84452 | 11152 | 79648736 |
| Neuromuscular block prolonged | 30.77 | 9.67 | 17 | 84483 | 1013 | 79658875 |
| Asthenia | 30.73 | 9.67 | 734 | 83766 | 510955 | 79148933 |
| Airway peak pressure increased | 30.23 | 9.67 | 12 | 84488 | 334 | 79659554 |
| Gene mutation | 30.02 | 9.67 | 24 | 84476 | 2662 | 79657226 |
| Small intestinal obstruction | 29.36 | 9.67 | 79 | 84421 | 27193 | 79632695 |
| Colitis | 29.11 | 9.67 | 154 | 84346 | 73153 | 79586735 |
| Hypersensitivity | 29.09 | 9.67 | 161 | 84339 | 262078 | 79397810 |
| Alopecia | 29.09 | 9.67 | 136 | 84364 | 231219 | 79428669 |
| Proctitis | 29.09 | 9.67 | 35 | 84465 | 6397 | 79653491 |
| Radiculopathy | 28.96 | 9.67 | 41 | 84459 | 8783 | 79651105 |
| Irritable bowel syndrome | 28.76 | 9.67 | 15 | 84485 | 62226 | 79597662 |
| Discomfort | 28.66 | 9.67 | 56 | 84444 | 125561 | 79534327 |
| Vaginal haemorrhage | 28.50 | 9.67 | 68 | 84432 | 21749 | 79638139 |
| Anhedonia | 28.21 | 9.67 | 54 | 84446 | 14844 | 79645044 |
| Drug ineffective | 28.03 | 9.67 | 903 | 83597 | 1080010 | 78579878 |
| COVID-19 | 27.48 | 9.67 | 81 | 84419 | 157593 | 79502295 |
| Gastrointestinal disorder | 26.58 | 9.67 | 56 | 84444 | 122149 | 79537739 |
| Blood lactic acid increased | 26.39 | 9.67 | 48 | 84452 | 12696 | 79647192 |
| Lung hyperinflation | 26.04 | 9.67 | 19 | 84481 | 1840 | 79658048 |
| Oxygen saturation abnormal | 25.92 | 9.67 | 28 | 84472 | 4554 | 79655334 |
| Therapy cessation | 25.75 | 9.67 | 93 | 84407 | 37469 | 79622419 |
| Emotional distress | 24.93 | 9.67 | 96 | 84404 | 39873 | 79620015 |
| Fall | 24.72 | 9.67 | 684 | 83816 | 486945 | 79172943 |
| Sopor | 24.62 | 9.67 | 3 | 84497 | 33007 | 79626881 |
| Renal injury | 24.57 | 9.67 | 55 | 84445 | 16872 | 79643016 |
| Blood magnesium increased | 24.49 | 9.67 | 24 | 84476 | 3482 | 79656406 |
| Full blood count decreased | 24.30 | 9.67 | 73 | 84427 | 26746 | 79633142 |
| Urticaria thermal | 24.12 | 9.67 | 11 | 84489 | 434 | 79659454 |
| Maternal exposure during delivery | 24.11 | 9.67 | 16 | 84484 | 1330 | 79658558 |
| Device dislocation | 23.83 | 9.67 | 71 | 84429 | 25899 | 79633989 |
| Premature labour | 23.24 | 9.67 | 36 | 84464 | 8354 | 79651534 |
| Caesarean section | 23.20 | 9.67 | 45 | 84455 | 12490 | 79647398 |
| Pleocytosis | 23.14 | 9.67 | 16 | 84484 | 1423 | 79658465 |
| Status asthmaticus | 22.76 | 9.67 | 14 | 84486 | 1020 | 79658868 |
| Administration site erythema | 22.76 | 9.67 | 10 | 84490 | 361 | 79659527 |
| Muscle spasms | 22.71 | 9.67 | 284 | 84216 | 174446 | 79485442 |
| C-reactive protein increased | 22.68 | 9.67 | 66 | 84434 | 128961 | 79530927 |
| Blister | 22.58 | 9.67 | 59 | 84441 | 119417 | 79540471 |
| Injury | 22.52 | 9.67 | 150 | 84350 | 77346 | 79582542 |
| Rhabdomyolysis | 21.81 | 9.67 | 48 | 84452 | 103083 | 79556805 |
| Neuromuscular blockade | 21.35 | 9.67 | 11 | 84489 | 569 | 79659319 |
| Musculoskeletal stiffness | 21.33 | 9.67 | 104 | 84396 | 174904 | 79484984 |
| Fibromyalgia | 21.31 | 9.67 | 22 | 84478 | 64318 | 79595570 |
| Blood pressure fluctuation | 21.08 | 9.67 | 24 | 84476 | 67121 | 79592767 |
| Chills | 21.06 | 9.67 | 261 | 84239 | 159973 | 79499915 |
| Blood albumin decreased | 21.04 | 9.67 | 65 | 84435 | 24178 | 79635710 |
| Encephalopathy | 20.52 | 9.67 | 132 | 84368 | 67265 | 79592623 |
| Rheumatic fever | 20.30 | 9.67 | 3 | 84497 | 28522 | 79631366 |
| Platelet count decreased | 20.23 | 9.67 | 304 | 84196 | 194360 | 79465528 |
| Drug hypersensitivity | 20.09 | 9.67 | 211 | 84289 | 298705 | 79361183 |
| Nausea | 19.83 | 9.67 | 1220 | 83280 | 955976 | 78703912 |
| Atrial fibrillation | 19.78 | 9.67 | 307 | 84193 | 197579 | 79462309 |
| Haemoglobin decreased | 19.75 | 9.67 | 338 | 84162 | 221781 | 79438107 |
| Diabetes mellitus | 19.62 | 9.67 | 33 | 84467 | 78357 | 79581531 |
| Type 2 diabetes mellitus | 19.52 | 9.67 | 19 | 84481 | 57103 | 79602785 |
| Hypokalaemia | 19.52 | 9.67 | 236 | 84264 | 143804 | 79516084 |
| Swelling | 19.43 | 9.67 | 142 | 84358 | 216569 | 79443319 |
| Pulmonary hypertension | 19.08 | 9.67 | 101 | 84399 | 47979 | 79611909 |
| Mobility decreased | 19.02 | 9.67 | 66 | 84434 | 122109 | 79537779 |
| Anxiety | 18.56 | 9.67 | 368 | 84132 | 248144 | 79411744 |
| Electrocardiogram QT prolonged | 18.42 | 9.67 | 161 | 84339 | 90225 | 79569663 |
| Nasopharyngitis | 18.40 | 9.67 | 176 | 84324 | 253705 | 79406183 |
| Dizziness | 18.27 | 9.67 | 706 | 83794 | 525735 | 79134153 |
| Abdominal pain | 18.21 | 9.67 | 541 | 83959 | 389028 | 79270860 |
| Pantoea agglomerans infection | 18.21 | 9.67 | 6 | 84494 | 96 | 79659792 |
| Myelosuppression | 18.19 | 9.67 | 10 | 84490 | 40286 | 79619602 |
| Respiratory tract infection bacterial | 17.94 | 9.67 | 16 | 84484 | 2061 | 79657827 |
| Intentional self-injury | 17.89 | 9.67 | 6 | 84494 | 32413 | 79627475 |
| Dyspepsia | 17.88 | 9.67 | 185 | 84315 | 108502 | 79551386 |
| Normal newborn | 17.74 | 9.67 | 29 | 84471 | 7043 | 79652845 |
| Osteonecrosis of jaw | 17.74 | 9.67 | 12 | 84488 | 43214 | 79616674 |
| Small for dates baby | 17.44 | 9.67 | 9 | 84491 | 467 | 79659421 |
| Constipation | 17.24 | 9.67 | 407 | 84093 | 282643 | 79377245 |
| Ill-defined disorder | 17.17 | 9.67 | 27 | 84473 | 65848 | 79594040 |
| Pleural effusion | 17.14 | 9.67 | 232 | 84268 | 145030 | 79514858 |
| Metabolic encephalopathy | 17.13 | 9.67 | 33 | 84467 | 9114 | 79650774 |
| Pelvic pain | 16.72 | 9.67 | 41 | 84459 | 13340 | 79646548 |
| Hospice care | 16.65 | 9.67 | 35 | 84465 | 10289 | 79649599 |
| PO2 decreased | 16.57 | 9.67 | 18 | 84482 | 2945 | 79656943 |
| Agranulocytosis | 16.56 | 9.67 | 14 | 84486 | 45016 | 79614872 |
| Frequent bowel movements | 16.07 | 9.67 | 68 | 84432 | 29471 | 79630417 |
| Red blood cell sedimentation rate increased | 16.03 | 9.67 | 15 | 84485 | 45927 | 79613961 |
| Cytomegalovirus infection | 16.00 | 9.67 | 13 | 84487 | 42631 | 79617257 |
| Febrile neutropenia | 15.90 | 9.67 | 338 | 84162 | 230661 | 79429227 |
| Inflammation | 15.73 | 9.67 | 49 | 84451 | 93704 | 79566184 |
| Nail bed tenderness | 15.67 | 9.67 | 8 | 84492 | 406 | 79659482 |
| Vulvovaginal swelling | 15.65 | 9.67 | 8 | 84492 | 407 | 79659481 |
| Vitamin B6 increased | 15.65 | 9.67 | 4 | 84496 | 24 | 79659864 |
| Neuropathy peripheral | 15.59 | 9.67 | 223 | 84277 | 141082 | 79518806 |
| Weight increased | 15.47 | 9.67 | 204 | 84296 | 277182 | 79382706 |
| Labelled drug-drug interaction medication error | 15.46 | 9.67 | 5 | 84495 | 27645 | 79632243 |
| Endometritis | 15.44 | 9.67 | 10 | 84490 | 798 | 79659090 |
| Accidental exposure to product | 15.30 | 9.67 | 7 | 84493 | 31315 | 79628573 |
| Impaired healing | 15.29 | 9.67 | 45 | 84455 | 87610 | 79572278 |
| Drug reaction with eosinophilia and systemic symptoms | 15.21 | 9.67 | 28 | 84472 | 64216 | 79595672 |
| Bacteraemia | 15.18 | 9.67 | 72 | 84428 | 32752 | 79627136 |
| Blood pressure systolic increased | 15.15 | 9.67 | 30 | 84470 | 66956 | 79592932 |
| Torsade de pointes | 15.14 | 9.67 | 50 | 84450 | 19262 | 79640626 |
| Flatulence | 15.11 | 9.67 | 87 | 84413 | 42637 | 79617251 |
| Unresponsive to stimuli | 15.03 | 9.67 | 106 | 84394 | 55682 | 79604206 |
| Hepatic cytolysis | 15.02 | 9.67 | 5 | 84495 | 27146 | 79632742 |
| Abdominal discomfort | 14.87 | 9.67 | 182 | 84318 | 250545 | 79409343 |
| Interstitial lung disease | 14.85 | 9.67 | 65 | 84435 | 112535 | 79547353 |
| Hypocalcaemia | 14.72 | 9.67 | 97 | 84403 | 49827 | 79610061 |
| Colitis ulcerative | 14.49 | 9.67 | 74 | 84426 | 34668 | 79625220 |
| Atelectasis | 14.37 | 9.67 | 70 | 84430 | 32187 | 79627701 |
| Product contamination microbial | 14.01 | 9.67 | 10 | 84490 | 936 | 79658952 |
| Transfusion | 13.93 | 9.67 | 52 | 84448 | 21278 | 79638610 |
| Obstructive airways disorder | 13.92 | 9.67 | 8 | 84492 | 31451 | 79628437 |
| Asthma | 13.87 | 9.67 | 85 | 84415 | 135010 | 79524878 |
| Loss of personal independence in daily activities | 13.66 | 9.67 | 59 | 84441 | 102521 | 79557367 |
| Cellulitis | 13.62 | 9.67 | 176 | 84324 | 108884 | 79551004 |
| Anorgasmia | 13.58 | 9.67 | 11 | 84489 | 1243 | 79658645 |
| Epilepsy | 13.50 | 9.67 | 14 | 84486 | 40846 | 79619042 |
| Flushing | 13.47 | 9.67 | 148 | 84352 | 88120 | 79571768 |
| Failure to thrive | 13.45 | 9.67 | 35 | 84465 | 11809 | 79648079 |
| Complication associated with device | 13.45 | 9.67 | 45 | 84455 | 17451 | 79642437 |
| Aspartate aminotransferase increased | 13.44 | 9.67 | 214 | 84286 | 138427 | 79521461 |
| Fatigue | 13.40 | 9.67 | 1151 | 83349 | 928576 | 78731312 |
| Eosinophilia | 13.39 | 9.67 | 17 | 84483 | 45328 | 79614560 |
| Postpartum haemorrhage | 13.21 | 9.67 | 12 | 84488 | 1583 | 79658305 |
| Burkholderia test positive | 13.08 | 9.67 | 8 | 84492 | 577 | 79659311 |
| HELLP syndrome | 13.05 | 9.67 | 9 | 84491 | 797 | 79659091 |
| Drug-induced liver injury | 12.99 | 9.67 | 32 | 84468 | 66085 | 79593803 |
| Haematocrit decreased | 12.90 | 9.67 | 110 | 84390 | 61202 | 79598686 |
| Product complaint | 12.73 | 9.67 | 37 | 84463 | 13312 | 79646576 |
| Drug resistance | 12.29 | 9.67 | 16 | 84484 | 42197 | 79617691 |
| Bursitis | 12.16 | 9.67 | 12 | 84488 | 35832 | 79624056 |
| Grip strength decreased | 12.15 | 9.67 | 4 | 84496 | 21865 | 79638023 |
| Incision site pain | 12.15 | 9.67 | 15 | 84485 | 2815 | 79657073 |
| Mixed dementia | 12.12 | 9.67 | 6 | 84494 | 285 | 79659603 |
| Behaviour disorder | 12.10 | 9.67 | 23 | 84477 | 6290 | 79653598 |
| Pneumocystis jirovecii pneumonia | 12.08 | 9.67 | 10 | 84490 | 32498 | 79627390 |
| Macroglossia | 12.04 | 9.67 | 10 | 84490 | 1171 | 79658717 |
| Product prescribing error | 12.03 | 9.67 | 18 | 84482 | 44795 | 79615093 |
| Dyspnoea | 12.03 | 9.67 | 1059 | 83441 | 855966 | 78803922 |
| Dizziness postural | 11.98 | 9.67 | 33 | 84467 | 11516 | 79648372 |
| Electroencephalogram abnormal | 11.93 | 9.67 | 21 | 84479 | 5413 | 79654475 |
| Antinuclear antibody positive | 11.86 | 9.67 | 26 | 84474 | 7864 | 79652024 |
| Carbohydrate antigen 125 increased | 11.75 | 9.67 | 13 | 84487 | 2171 | 79657717 |
| Apnoea | 11.70 | 9.67 | 33 | 84467 | 11671 | 79648217 |
| Infection | 11.64 | 9.67 | 183 | 84317 | 241529 | 79418359 |
| White blood cell count decreased | 11.53 | 9.67 | 271 | 84229 | 188017 | 79471871 |
| Product contamination | 11.47 | 9.67 | 10 | 84490 | 1250 | 79658638 |
| Joint range of motion decreased | 11.46 | 9.67 | 11 | 84489 | 33271 | 79626617 |
| Wrong technique in product usage process | 11.43 | 9.67 | 40 | 84460 | 73835 | 79586053 |
| Prescribed overdose | 11.40 | 9.67 | 14 | 84486 | 37869 | 79622019 |
| Muscular weakness | 11.32 | 9.67 | 236 | 84264 | 160493 | 79499395 |
| Rectal haemorrhage | 11.22 | 9.67 | 127 | 84373 | 76173 | 79583715 |
| Tachypnoea | 11.15 | 9.67 | 65 | 84435 | 31998 | 79627890 |
| Fluid retention | 11.09 | 9.67 | 118 | 84382 | 69691 | 79590197 |
| Anaemia | 11.06 | 9.67 | 577 | 83923 | 444438 | 79215450 |
| Urine output decreased | 11.00 | 9.67 | 43 | 84457 | 17979 | 79641909 |
| Stillbirth | 11.00 | 9.67 | 17 | 84483 | 3938 | 79655950 |
| Hip arthroplasty | 10.99 | 9.67 | 13 | 84487 | 35743 | 79624145 |
| Hyporeflexia | 10.86 | 9.67 | 16 | 84484 | 3552 | 79656336 |
| Hypercapnia | 10.76 | 9.67 | 27 | 84473 | 8908 | 79650980 |
| Splenic vein thrombosis | 10.72 | 9.67 | 8 | 84492 | 802 | 79659086 |
| Ureteric stenosis | 10.62 | 9.67 | 10 | 84490 | 1382 | 79658506 |
| Hip fracture | 10.46 | 9.67 | 62 | 84438 | 30699 | 79629189 |
| Sinus tachycardia | 10.45 | 9.67 | 71 | 84429 | 36837 | 79623051 |
| Hypophagia | 10.41 | 9.67 | 83 | 84417 | 45284 | 79614604 |
| Blood pressure diastolic decreased | 10.38 | 9.67 | 10 | 84490 | 30206 | 79629682 |
| Impaired work ability | 10.25 | 9.67 | 4 | 84496 | 19677 | 79640211 |
| Pulmonary embolism | 10.19 | 9.67 | 246 | 84254 | 171408 | 79488480 |
| Pulmonary arterial hypertension | 10.19 | 9.67 | 58 | 84442 | 28308 | 79631580 |
| Laryngeal pain | 10.18 | 9.67 | 21 | 84479 | 6093 | 79653795 |
| Hepatitis | 10.16 | 9.67 | 28 | 84472 | 55699 | 79604189 |
| Wound drainage | 10.11 | 9.67 | 9 | 84491 | 1157 | 79658731 |
| Respiratory tract infection viral | 10.06 | 9.67 | 17 | 84483 | 4242 | 79655646 |
| Rheumatoid nodule | 10.03 | 9.67 | 3 | 84497 | 17435 | 79642453 |
| Therapy partial responder | 9.99 | 9.67 | 3 | 84497 | 17394 | 79642494 |
| Suspected transmission of an infectious agent via product | 9.98 | 9.67 | 9 | 84491 | 1177 | 79658711 |
| Liver injury | 9.92 | 9.67 | 29 | 84471 | 56585 | 79603303 |
| Enterococcal bacteraemia | 9.69 | 9.67 | 14 | 84486 | 3054 | 79656834 |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Product preparation error | 36.31 | 31.69 | 10 | 90 | 83 | 89609 |
| Source | Code | Description |
|---|---|---|
| ATC | A06AD04 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Osmotically acting laxatives |
| ATC | A12CC02 | ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS OTHER MINERAL SUPPLEMENTS Magnesium |
| ATC | B05XA05 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS I.V. SOLUTION ADDITIVES Electrolyte solutions |
| ATC | D11AX05 | DERMATOLOGICALS OTHER DERMATOLOGICAL PREPARATIONS OTHER DERMATOLOGICAL PREPARATIONS Other dermatologicals |
| ATC | V04CC02 | VARIOUS DIAGNOSTIC AGENTS OTHER DIAGNOSTIC AGENTS Tests for bile duct patency |
| MeSH PA | D000700 | Analgesics |
| MeSH PA | D000777 | Anesthetics |
| MeSH PA | D000889 | Anti-Arrhythmia Agents |
| MeSH PA | D000927 | Anticonvulsants |
| MeSH PA | D002121 | Calcium Channel Blockers |
| MeSH PA | D000077264 | Calcium-Regulating Hormones and Agents |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D002492 | Central Nervous System Depressants |
| MeSH PA | D049990 | Membrane Transport Modulators |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D012102 | Reproductive Control Agents |
| MeSH PA | D018689 | Sensory System Agents |
| MeSH PA | D015149 | Tocolytic Agents |
| CHEBI has role | CHEBI:50503 | laxante |
| CHEBI has role | CHEBI:75325 | cathartics |
| CHEBI has role | CHEBI:33287 | fertilizers |
| CHEBI has role | CHEBI:35554 | cardiovascular agent |
| CHEBI has role | CHEBI:35623 | anticonvulsants |
| CHEBI has role | CHEBI:38070 | antiarrhythmic agent |
| CHEBI has role | CHEBI:38215 | calcium channel blockers |
| CHEBI has role | CHEBI:38867 | anaesthetic |
| CHEBI has role | CHEBI:66993 | tocolytic drugs |
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Constipation | indication | 14760008 | DOID:2089 |
| Mild pre-eclampsia | indication | 41114007 | |
| Severe pre-eclampsia | indication | 46764007 | |
| Hypomagnesemia | indication | 190855004 | |
| Eclampsia in pregnancy | indication | 198992004 | |
| Incomplete passage of stool | indication | 249515001 | |
| Torsades de pointes | off-label use | 31722008 | |
| Atypical Ventricular Tachycardia | off-label use | ||
| Hypocalcemia | contraindication | 5291005 | |
| Hyperkalemia | contraindication | 14140009 | |
| Complete atrioventricular block | contraindication | 27885002 | |
| Dehydration | contraindication | 34095006 | |
| Gastrointestinal ulcer | contraindication | 40845000 | |
| Congenital myotonia, autosomal dominant form | contraindication | 57938005 | |
| Acute nephropathy | contraindication | 58574008 | |
| Hypermagnesemia | contraindication | 66978005 | |
| Appendicitis | contraindication | 74400008 | DOID:8337 |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Gastrointestinal obstruction | contraindication | 126765001 | |
| Gastroparesis | contraindication | 235675006 | |
| Chronic diarrhea | contraindication | 236071009 | |
| Hyporeninemic hypoaldosteronism | contraindication | 236464008 | |
| Familial hyperkalemic periodic paralysis | contraindication | 304737009 | DOID:14451 |
| Severe dehydration | contraindication | 450316000 |
| Species | Use | Relation |
|---|---|---|
| Cattles | Used with sedative-relaxant and general anesthesia agents | Indication |
| Horses | Used with sedative-relaxant and general anesthesia agents | Indication |
| Product | Applicant | Ingredients |
|---|---|---|
| Chloropent | Zoetis Inc. | 3 |
None
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
|---|---|---|---|---|---|---|---|---|---|---|
| 1.6GM/BOT;3.13GM/BOT;17.5GM/BOT | SUPREP BOWEL PREP KIT | BRAINTREE LABS | N022372 | Aug. 5, 2010 | RX | SOLUTION | ORAL | 6946149 | March 7, 2023 | GASTROINTESTINAL LAVAGE INDICATED FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY IN ADULTS |
| 0.225GM;0.188GM;1.479GM | SUTAB | BRAINTREE LABS | N213135 | Nov. 10, 2020 | RX | TABLET | ORAL | 11033498 | Aug. 4, 2037 | GASTROINTESTINAL TABLETS INDICATED FOR CLEANSING THE COLON IN PREPARATION FOR COLONOSCOPY |
| 0.225GM;0.188GM;1.479GM | SUTAB | BRAINTREE LABS | N213135 | Nov. 10, 2020 | RX | TABLET | ORAL | 11382864 | Aug. 4, 2037 | GASTROINTESTINAL TABLETS INDICATED FOR CLEANSING THE COLON IN PREPARATION FOR COLONOSCOPY |
| Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Exclusivity date | Description |
|---|---|---|---|---|---|---|---|---|---|
| 1.6GM/BOT;3.13GM/BOT;17.5GM/BOT | SODIUM SULFATE, POTASSIUM SULFATE AND MAGNESIUM SULFATE | NOVEL LABS INC | A202511 | Feb. 23, 2017 | RX | SOLUTION | ORAL | March 6, 2023 | PATENT CHALLENGE |
| 0.225GM;0.188GM;1.479GM | SUTAB | BRAINTREE LABS | N213135 | Nov. 10, 2020 | RX | TABLET | ORAL | Nov. 10, 2023 | NEW PRODUCT |
| 0.9GM/BOT;178.7GM/BOT;1.12GM/BOT;0.5GM/BOT;7.3GM/BOT | SUFLAVE | BRAINTREE LABS | N215344 | June 15, 2023 | RX | FOR SOLUTION | ORAL | June 15, 2026 | NEW PRODUCT |
| 1.6GM/BOT;3.13GM/BOT;17.5GM/BOT | SUPREP BOWEL PREP KIT | BRAINTREE LABS | N022372 | Aug. 5, 2010 | RX | SOLUTION | ORAL | Aug. 5, 2027 | FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY IN PEDIATRIC PATIENTS 12 YEARS OF AGE AND OLDER |
None
| ID | Source |
|---|---|
| 4019181 | VUID |
| N0000147424 | NUI |
| 10034-99-8 | SECONDARY_CAS_RN |
| 4000969 | VANDF |
| 4017468 | VANDF |
| 4017680 | VANDF |
| 4019181 | VANDF |
| C0024480 | UMLSCUI |
| CHEBI:32599 | CHEBI |
| CHEMBL2021423 | ChEMBL_ID |
| CHEMBL3989857 | ChEMBL_ID |
| D008278 | MESH_DESCRIPTOR_UI |
| DB00653 | DRUGBANK_ID |
| 24083 | PUBCHEM_CID |
| 1053346 | RXNORM |
| 173828 | MMSL |
| 173829 | MMSL |
| 26390 | MMSL |
| 36335 | MMSL |
| 5017 | MMSL |
| 5259 | MMSL |
| 6287 | MMSL |
| 7114 | MMSL |
| d00468 | MMSL |
| 000789 | NDDF |
| 001184 | NDDF |
| 003022 | NDDF |
| 006708 | NDDF |
| 1269139001 | SNOMEDCT_US |
| 37400007 | SNOMEDCT_US |
| 387202002 | SNOMEDCT_US |
| 725797001 | SNOMEDCT_US |
| SK47B8698T | UNII |
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Magnesium Sulfate in Water | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4204 | INJECTION, SOLUTION | 2 g | INTRAVENOUS | ANDA | 21 sections |
| Magnesium Sulfate in Water | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4204 | INJECTION, SOLUTION | 2 g | INTRAVENOUS | ANDA | 21 sections |
| Magnesium Sulfate in Water | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4205 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 21 sections |
| Magnesium Sulfate in Water | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4205 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 21 sections |
| Magnesium Sulfate in Water | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4206 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 21 sections |
| Magnesium Sulfate in Water | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4206 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 21 sections |
| Magnesium Sulfate in Dextrose | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4400 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
| TIS-U-SOL | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0190 | IRRIGANT | 20 mg | IRRIGATION | NDA | 5 sections |
| TIS-U-SOL | HUMAN PRESCRIPTION DRUG LABEL | 5 | 0338-0190 | IRRIGANT | 20 mg | IRRIGATION | NDA | 5 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1708 | INJECTION, SOLUTION | 2 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1708 | INJECTION, SOLUTION | 2 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1708 | INJECTION, SOLUTION | 2 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1708 | INJECTION, SOLUTION | 2 g | INTRAVENOUS | ANDA | 20 sections |
| MAGNESIUM SULFATE IN DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1709 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 23 sections |
| MAGNESIUM SULFATE IN DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1709 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 23 sections |
| MAGNESIUM SULFATE IN DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1709 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 23 sections |
| MAGNESIUM SULFATE IN DEXTROSE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1709 | INJECTION, SOLUTION | 10 mg | INTRAVENOUS | ANDA | 23 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1715 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1715 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1715 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1715 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1719 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1719 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1719 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Magnesium Sulfate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0338-1719 | INJECTION, SOLUTION | 4 g | INTRAVENOUS | ANDA | 20 sections |
| Epsom Salt | HUMAN OTC DRUG LABEL | 1 | 0363-0395 | GRANULE | 1 g | ORAL | OTC monograph not final | 15 sections |
| Epsom Salt | HUMAN OTC DRUG LABEL | 1 | 0363-0942 | GRANULE, FOR SOLUTION | 1 g | ORAL | OTC monograph not final | 15 sections |
| Epsom Salt | HUMAN OTC DRUG LABEL | 1 | 0363-0942 | GRANULE, FOR SOLUTION | 1 g | ORAL | OTC monograph not final | 15 sections |
| Humco Epson Salt | HUMAN OTC DRUG LABEL | 1 | 0395-0807 | POWDER, FOR SOLUTION | 1000 mg | ORAL | OTC monograph not final | 10 sections |
| Humco Epson Salt | HUMAN OTC DRUG LABEL | 1 | 0395-0807 | POWDER, FOR SOLUTION | 1000 mg | ORAL | OTC monograph not final | 10 sections |