magnesium citrate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4281 3344-18-1

Description:

MoleculeDescription

Synonyms:

  • magnesium citrate
  • citric acid magnesium salt
  • trimagnesium dicitrate
  • Molecular weight: 451.11
  • Formula: C12H10Mg3O14
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 140.62
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
2 g O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Visual snow syndrome 43.49 16.00 7 5852 49 63483114
Rhonchi 39.27 16.00 13 5846 2563 63480600
Gastrooesophageal reflux disease 38.89 16.00 46 5813 95593 63387570
Tetany 38.29 16.00 12 5847 1989 63481174
Focal segmental glomerulosclerosis 37.51 16.00 11 5848 1457 63481706
Drug use disorder 27.61 16.00 12 5847 4972 63478191
Anticipatory anxiety 26.03 16.00 8 5851 1243 63481920
Blepharospasm 25.49 16.00 12 5847 5984 63477179
Asthenia 25.07 16.00 85 5774 383519 63099644
Taste disorder 20.98 16.00 14 5845 13648 63469515
Night sweats 20.69 16.00 24 5835 48790 63434373
Hyperaesthesia 20.45 16.00 12 5847 9346 63473817
Hypermagnesaemia 19.23 16.00 6 5853 980 63482183
Constipation 17.53 16.00 53 5806 224890 63258273
Pruritus allergic 16.45 16.00 6 5853 1576 63481587
Nerve block 16.27 16.00 5 5854 777 63482386

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Constipation 31.91 20.78 38 1845 136944 34818104
Burkholderia test positive 22.21 20.78 6 1877 1017 34954031

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Visual snow syndrome 43.69 16.17 7 6670 53 79737658
Tetany 35.78 16.17 12 6665 2716 79734995
Rhonchi 34.80 16.17 13 6664 4023 79733688
Drug use disorder 34.26 16.17 16 6661 8635 79729076
Constipation 33.01 16.17 73 6604 282977 79454734
Gastrooesophageal reflux disease 31.23 16.17 41 6636 104205 79633506
Anticipatory anxiety 27.10 16.17 8 6669 1196 79736515
Blepharospasm 26.88 16.17 12 6665 5839 79731872
Focal segmental glomerulosclerosis 22.58 16.17 9 6668 3312 79734399
Taste disorder 20.35 16.17 14 6663 15809 79721902
Hypermagnesaemia 18.43 16.17 6 6671 1238 79736473
Asthenia 18.34 16.17 88 6589 511601 79226110
Pruritus allergic 17.74 16.17 6 6671 1393 79736318
Nerve block 17.20 16.17 5 6672 708 79737003
Facet joint syndrome 16.94 16.17 11 6666 11291 79726420
Abdominal pain upper 16.91 16.17 49 6628 223770 79513941
Adverse drug reaction 16.69 16.17 24 6653 66368 79671343
Night sweats 16.39 16.17 21 6656 52074 79685637

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A06AD19 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Osmotically acting laxatives
ATC A12CC04 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
OTHER MINERAL SUPPLEMENTS
Magnesium
ATC B05CB03 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
IRRIGATING SOLUTIONS
Salt solutions
MeSH PA D002400 Cathartics
MeSH PA D005765 Gastrointestinal Agents
CHEBI has role CHEBI:50503 laxante

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hypocalcemia indication 5291005
Constipation indication 14760008 DOID:2089
Osteoporosis indication 64859006 DOID:11476
Postmenopausal osteoporosis indication 102447009
Incomplete passage of stool indication 249515001
Peptic ulcer contraindication 13200003 DOID:750
Hyperkalemia contraindication 14140009
Hyperphosphatemia contraindication 20165001 DOID:0050459
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Dehydration contraindication 34095006
Chronic heart failure contraindication 48447003
Metabolic acidosis contraindication 59455009
Diarrhea contraindication 62315008
Hypercalcemia contraindication 66931009 DOID:12678
Hypermagnesemia contraindication 66978005
Hyperparathyroidism contraindication 66999008 DOID:13543
Hypercalciuria contraindication 71938000
Appendicitis contraindication 74400008 DOID:8337
Gastrointestinal hemorrhage contraindication 74474003
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Gastrointestinal obstruction contraindication 126765001
Impaired renal function disorder contraindication 197663003
Gastroparesis contraindication 235675006
Rhabdomyolysis contraindication 240131006
Esophageal dysmotility contraindication 266434009 DOID:9192
Arteriosclerosis obliterans contraindication 361133006 DOID:5160
Primary adrenocortical insufficiency contraindication 373662000
Ketoacidosis in diabetes mellitus contraindication 420422005 DOID:1837
Esophageal Compression contraindication
Genitourinary Tract Infections contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019514 VUID
N0000147634 NUI
D03265 KEGG_DRUG
4019514 VANDF
C0126774 UMLSCUI
CHEBI:131391 CHEBI
CHEMBL3989480 ChEMBL_ID
DB11110 DRUGBANK_ID
C110422 MESH_SUPPLEMENTAL_RECORD_UI
RHO26O1T9V UNII
6099959 PUBCHEM_CID
52356 RXNORM
28364 MMSL
5011 MMSL
5563 MMSL
d01008 MMSL
001185 NDDF
006958 NDDF
008279 NDDF
12495006 SNOMEDCT_US
387052002 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0015 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citratesaline laxative HUMAN OTC DRUG LABEL 1 0363-0328 LIQUID 1.75 g ORAL OTC MONOGRAPH NOT FINAL 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0415 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0416 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0427 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0629 LIQUID 1.75 g ORAL OTC MONOGRAPH NOT FINAL 16 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0667 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-0667 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
citroma HUMAN OTC DRUG LABEL 1 0363-0693 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-7162 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-7162 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Magnesium Citrate HUMAN OTC DRUG LABEL 1 0363-7162 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8162 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8164 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8164 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8164 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8166 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8166 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
citroma HUMAN OTC DRUG LABEL 1 0363-8166 LIQUID 1.75 g ORAL OTC monograph not final 15 sections
Citroma HUMAN OTC DRUG LABEL 1 0869-0162 LIQUID 1.75 g ORAL OTC monograph not final 16 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0164 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0166 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0166 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma HUMAN OTC DRUG LABEL 1 0869-0525 LIQUID 1.75 g ORAL OTC monograph not final 12 sections
Citroma HUMAN OTC DRUG LABEL 1 0869-0667 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma HUMAN OTC DRUG LABEL 1 0869-0667 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma Magnesium Citrate HUMAN OTC DRUG LABEL 1 0869-0686 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
Citroma Magnesium Citrate HUMAN OTC DRUG LABEL 1 0869-0686 LIQUID 1.75 g ORAL OTC monograph not final 14 sections
citroma HUMAN OTC DRUG LABEL 1 0869-0693 LIQUID 1.75 g ORAL OTC monograph not final 14 sections