Stem definition | Drug id | CAS RN |
---|---|---|
4281 | 3344-18-1 |
Molecule | Description |
---|---|
Synonyms:
|
|
Dose | Unit | Route |
---|---|---|
2 | g | O |
None
Date | Agency | Company | Orphan |
---|---|---|---|
None | FDA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Visual snow syndrome | 43.49 | 16.00 | 7 | 5852 | 49 | 63483114 |
Rhonchi | 39.27 | 16.00 | 13 | 5846 | 2563 | 63480600 |
Gastrooesophageal reflux disease | 38.89 | 16.00 | 46 | 5813 | 95593 | 63387570 |
Tetany | 38.29 | 16.00 | 12 | 5847 | 1989 | 63481174 |
Focal segmental glomerulosclerosis | 37.51 | 16.00 | 11 | 5848 | 1457 | 63481706 |
Drug use disorder | 27.61 | 16.00 | 12 | 5847 | 4972 | 63478191 |
Anticipatory anxiety | 26.03 | 16.00 | 8 | 5851 | 1243 | 63481920 |
Blepharospasm | 25.49 | 16.00 | 12 | 5847 | 5984 | 63477179 |
Asthenia | 25.07 | 16.00 | 85 | 5774 | 383519 | 63099644 |
Taste disorder | 20.98 | 16.00 | 14 | 5845 | 13648 | 63469515 |
Night sweats | 20.69 | 16.00 | 24 | 5835 | 48790 | 63434373 |
Hyperaesthesia | 20.45 | 16.00 | 12 | 5847 | 9346 | 63473817 |
Hypermagnesaemia | 19.23 | 16.00 | 6 | 5853 | 980 | 63482183 |
Constipation | 17.53 | 16.00 | 53 | 5806 | 224890 | 63258273 |
Pruritus allergic | 16.45 | 16.00 | 6 | 5853 | 1576 | 63481587 |
Nerve block | 16.27 | 16.00 | 5 | 5854 | 777 | 63482386 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Constipation | 31.91 | 20.78 | 38 | 1845 | 136944 | 34818104 |
Burkholderia test positive | 22.21 | 20.78 | 6 | 1877 | 1017 | 34954031 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Visual snow syndrome | 43.69 | 16.17 | 7 | 6670 | 53 | 79737658 |
Tetany | 35.78 | 16.17 | 12 | 6665 | 2716 | 79734995 |
Rhonchi | 34.80 | 16.17 | 13 | 6664 | 4023 | 79733688 |
Drug use disorder | 34.26 | 16.17 | 16 | 6661 | 8635 | 79729076 |
Constipation | 33.01 | 16.17 | 73 | 6604 | 282977 | 79454734 |
Gastrooesophageal reflux disease | 31.23 | 16.17 | 41 | 6636 | 104205 | 79633506 |
Anticipatory anxiety | 27.10 | 16.17 | 8 | 6669 | 1196 | 79736515 |
Blepharospasm | 26.88 | 16.17 | 12 | 6665 | 5839 | 79731872 |
Focal segmental glomerulosclerosis | 22.58 | 16.17 | 9 | 6668 | 3312 | 79734399 |
Taste disorder | 20.35 | 16.17 | 14 | 6663 | 15809 | 79721902 |
Hypermagnesaemia | 18.43 | 16.17 | 6 | 6671 | 1238 | 79736473 |
Asthenia | 18.34 | 16.17 | 88 | 6589 | 511601 | 79226110 |
Pruritus allergic | 17.74 | 16.17 | 6 | 6671 | 1393 | 79736318 |
Nerve block | 17.20 | 16.17 | 5 | 6672 | 708 | 79737003 |
Facet joint syndrome | 16.94 | 16.17 | 11 | 6666 | 11291 | 79726420 |
Abdominal pain upper | 16.91 | 16.17 | 49 | 6628 | 223770 | 79513941 |
Adverse drug reaction | 16.69 | 16.17 | 24 | 6653 | 66368 | 79671343 |
Night sweats | 16.39 | 16.17 | 21 | 6656 | 52074 | 79685637 |
None
Source | Code | Description |
---|---|---|
ATC | A06AD19 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR CONSTIPATION DRUGS FOR CONSTIPATION Osmotically acting laxatives |
ATC | A12CC04 | ALIMENTARY TRACT AND METABOLISM MINERAL SUPPLEMENTS OTHER MINERAL SUPPLEMENTS Magnesium |
ATC | B05CB03 | BLOOD AND BLOOD FORMING ORGANS BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS IRRIGATING SOLUTIONS Salt solutions |
MeSH PA | D002400 | Cathartics |
MeSH PA | D005765 | Gastrointestinal Agents |
CHEBI has role | CHEBI:50503 | laxante |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Hypocalcemia | indication | 5291005 | |
Constipation | indication | 14760008 | DOID:2089 |
Osteoporosis | indication | 64859006 | DOID:11476 |
Postmenopausal osteoporosis | indication | 102447009 | |
Incomplete passage of stool | indication | 249515001 | |
Peptic ulcer | contraindication | 13200003 | DOID:750 |
Hyperkalemia | contraindication | 14140009 | |
Hyperphosphatemia | contraindication | 20165001 | DOID:0050459 |
Hypervitaminosis D | contraindication | 27712000 | DOID:9971 |
Sarcoidosis | contraindication | 31541009 | DOID:11335 |
Dehydration | contraindication | 34095006 | |
Chronic heart failure | contraindication | 48447003 | |
Metabolic acidosis | contraindication | 59455009 | |
Diarrhea | contraindication | 62315008 | |
Hypercalcemia | contraindication | 66931009 | DOID:12678 |
Hypermagnesemia | contraindication | 66978005 | |
Hyperparathyroidism | contraindication | 66999008 | DOID:13543 |
Hypercalciuria | contraindication | 71938000 | |
Appendicitis | contraindication | 74400008 | DOID:8337 |
Gastrointestinal hemorrhage | contraindication | 74474003 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Kidney stone | contraindication | 95570007 | |
Gastrointestinal obstruction | contraindication | 126765001 | |
Impaired renal function disorder | contraindication | 197663003 | |
Gastroparesis | contraindication | 235675006 | |
Rhabdomyolysis | contraindication | 240131006 | |
Esophageal dysmotility | contraindication | 266434009 | DOID:9192 |
Arteriosclerosis obliterans | contraindication | 361133006 | DOID:5160 |
Primary adrenocortical insufficiency | contraindication | 373662000 | |
Ketoacidosis in diabetes mellitus | contraindication | 420422005 | DOID:1837 |
Esophageal Compression | contraindication | ||
Genitourinary Tract Infections | contraindication |
None
None
None
None
None
None
ID | Source |
---|---|
4019514 | VUID |
N0000147634 | NUI |
D03265 | KEGG_DRUG |
4019514 | VANDF |
C0126774 | UMLSCUI |
CHEBI:131391 | CHEBI |
CHEMBL3989480 | ChEMBL_ID |
DB11110 | DRUGBANK_ID |
C110422 | MESH_SUPPLEMENTAL_RECORD_UI |
RHO26O1T9V | UNII |
6099959 | PUBCHEM_CID |
52356 | RXNORM |
28364 | MMSL |
5011 | MMSL |
5563 | MMSL |
d01008 | MMSL |
001185 | NDDF |
006958 | NDDF |
008279 | NDDF |
12495006 | SNOMEDCT_US |
387052002 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-0015 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
Magnesium Citratesaline laxative | HUMAN OTC DRUG LABEL | 1 | 0363-0328 | LIQUID | 1.75 g | ORAL | OTC MONOGRAPH NOT FINAL | 16 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-0415 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 16 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-0416 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 16 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-0427 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 16 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-0629 | LIQUID | 1.75 g | ORAL | OTC MONOGRAPH NOT FINAL | 16 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-0667 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-0667 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-0693 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-7162 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-7162 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0363-7162 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-8162 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-8164 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 16 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-8164 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 16 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-8164 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 16 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-8166 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-8166 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0363-8166 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 15 sections |
Citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0162 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 16 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0164 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0164 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0166 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0166 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
Citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0525 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 12 sections |
Citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0667 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
Citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0667 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
Citroma Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0869-0686 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
Citroma Magnesium Citrate | HUMAN OTC DRUG LABEL | 1 | 0869-0686 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |
citroma | HUMAN OTC DRUG LABEL | 1 | 0869-0693 | LIQUID | 1.75 g | ORAL | OTC monograph not final | 14 sections |