| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4279 | 9002-89-5 |
| Molecule | Description |
|---|---|
|
Synonyms:
|
A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.
|
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| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Gynaecomastia | 35.20 | 34.72 | 5 | 435 | 229 | 63488353 |
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| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Tear film insufficiency | indication | 46152009 | |
| Red eye | indication | 75705005 | |
| Keratoconjunctivitis sicca | off-label use | 302896008 | DOID:12895 |
| Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
| Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
| Conduction disorder of the heart | contraindication | 44808001 | |
| Heart disease | contraindication | 56265001 | DOID:114 |
| Arteriosclerotic vascular disease | contraindication | 72092001 | |
| Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
| Arterial aneurysm | contraindication | 233981004 | |
| Benign prostatic hyperplasia | contraindication | 266569009 | |
| Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
| Disorder of coronary artery | contraindication | 414024009 |
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| ID | Source |
|---|---|
| 4019529 | VUID |
| N0000147643 | NUI |
| D02320 | KEGG_DRUG |
| 4019529 | VANDF |
| C0032623 | UMLSCUI |
| CHEBI:17246 | CHEBI |
| CHEMBL3559671 | ChEMBL_ID |
| CHEMBL76101 | ChEMBL_ID |
| D011142 | MESH_DESCRIPTOR_UI |
| DB11060 | DRUGBANK_ID |
| 8570 | RXNORM |
| 60685 | MMSL |
| NOCODE | MMSL |
| 002533 | NDDF |
| 330790003 | SNOMEDCT_US |
| 83619009 | SNOMEDCT_US |
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