polyvinyl alcohol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4279 9002-89-5

Description:

MoleculeDescription

Synonyms:

  • polyvinyl alcohol
  • vinyl alcohol polymer
A polymer prepared from polyvinyl acetates by replacement of the acetate groups with hydroxyl groups. It is used as a pharmaceutic aid and ophthalmic lubricant as well as in the manufacture of surface coatings artificial sponges, cosmetics, and other products.
  • Molecular weight:
  • Formula: (C2H4O)n
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Gynaecomastia 36.11 31.61 5 425 154 50604540

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Tear film insufficiency indication 46152009
Red eye indication 75705005
Keratoconjunctivitis sicca off-label use 302896008 DOID:12895
Hyperthyroidism contraindication 34486009 DOID:7998
Hypertensive disorder contraindication 38341003 DOID:10763
Conduction disorder of the heart contraindication 44808001
Heart disease contraindication 56265001 DOID:114
Arteriosclerotic vascular disease contraindication 72092001
Diabetes mellitus contraindication 73211009 DOID:9351
Arterial aneurysm contraindication 233981004
Benign prostatic hyperplasia contraindication 266569009
Angle-closure glaucoma contraindication 392291006 DOID:13550
Disorder of coronary artery contraindication 414024009




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019529 VUID
N0000147643 NUI
D02320 KEGG_DRUG
4019529 VANDF
C0032623 UMLSCUI
CHEBI:17246 CHEBI
CHEMBL3559671 ChEMBL_ID
CHEMBL76101 ChEMBL_ID
D011142 MESH_DESCRIPTOR_UI
DB11060 DRUGBANK_ID
11199 PUBCHEM_CID
8570 RXNORM
60685 MMSL
NOCODE MMSL
002533 NDDF
330790003 SNOMEDCT_US
83619009 SNOMEDCT_US

Pharmaceutical products:

None