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selenium sulfide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4274 | 7488-56-4 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT1,AKT2,AKT3,ALK,AURKA,AURKB,AURKC,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK2,CDK4,CDK5,CDK9,CHEK1,CSF1R,DDR1,DYRK1B,DYRK3,EGFR,EIF2AK3,EPHB4,ERBB2,FLT1,FLT3,FLT4,GRK2,GSK3B,HIPK2,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,MAP2K6,MAP3K1,MAP3K10,MAP3K14,MAP3K2,MAP3K21,MAP3K3,MAP3K7,MAP4K1,MAP4K3,MAPK1,MAPK10,MAPK12,MAPK7,MAPK8,MAPK9,MAPKAPK2,MARK4,MELK,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIM1,PIM2,PIM3,PLK1,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK10,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ULK2 | 88 | |||
| kinase-selectivity-class | ACVR2A,ACVR2B,AXL,BRAF,CDK4,CDK9,DYRK1A,DYRK1B,DYRK3,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,HIPK2,IKBKB,JAK2,MAP2K3,MAP2K6,MAP3K14,MAPK12,MAPK7,PIK3CB,PIM3,PRKDC,STK33,SYK,TEK,TTK,UHMK1 | 30 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| May 17, 1951 | FDA | CHATTEM |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Lactobacillus test positive | 26.18 | 25.76 | 3 | 481 | 38 | 110588777 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D01AE13 | DERMATOLOGICALS ANTIFUNGALS FOR DERMATOLOGICAL USE ANTIFUNGALS FOR TOPICAL USE Other antifungals for topical use |
| MeSH PA | D003879 | Dermatologic Agents |
| CHEBI has role | CHEBI:35718 | antifungal agent |
| CHEBI has role | CHEBI:50177 | dermatologic drug |
Related Drugs by ATC class:
D01AE Other antifungals for topical use 23 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Seborrheic dermatitis | indication | 50563003 | DOID:8741 |
| Pityriasis versicolor | indication | 56454009 | DOID:9060 |
| Pityriasis simplex | indication | 200767005 | |
| Distinctive exudative discoid AND lichenoid chronic dermatosis of Sulzberger and Garbe | contraindication | 41580004 | |
| Inflammatory dermatosis | contraindication | 703938007 |
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Dogs | Cleansing shampoo | Indication |
| Dogs | Removing skin debris associated with dry eczema, seborrhea, and nonspecific dermatoses | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Seleen Suspension | Boehringer lngelheim Animal Health USA Inc. | 1 |
| SE S2 Shampoo | Intervet Inc. | 1 |
| Dandrex | Farnam Companies Inc. | 1 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4018219 | VUID |
| N0000179237 | NUI |
| D05815 | KEGG_DRUG |
| 4018219 | VANDF |
| C0074281 | UMLSCUI |
| CHEBI:135934 | CHEBI |
| CHEMBL1200680 | ChEMBL_ID |
| DB00971 | DRUGBANK_ID |
| C025698 | MESH_SUPPLEMENTAL_RECORD_UI |
| Z69D9E381Q | UNII |
| 24011 | PUBCHEM_CID |
| 36345 | RXNORM |
| 1565 | MMSL |
| 5451 | MMSL |
| 002005 | NDDF |
| 018124 | NDDF |
| 58292001 | SNOMEDCT_US |
| 768430000 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Walgreens Dandruff and Conditioner Cleansing and ConditioningAnti-dandruff | HUMAN OTC DRUG LABEL | 1 | 0363-4136 | SHAMPOO | 10 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| Walgreens Dandruff Maximum StrengthAnti-dandruff | HUMAN OTC DRUG LABEL | 1 | 0363-4139 | SHAMPOO | 10 mg | TOPICAL | OTC Monograph Drug | 13 sections |
| Walgreens Dandruff With Menthol/Selenium SulfideAnti-dandruff, anti-seborrheic dermatitis, anti-psoriasis | HUMAN OTC DRUG LABEL | 1 | 0363-4902 | SHAMPOO | 10 mg | TOPICAL | OTC Monograph Drug | 14 sections |
| Walgreens Clinical Strength Medicated DandruffAnti-dandruff, Anti-seborrheic dermatitis | HUMAN OTC DRUG LABEL | 1 | 0363-9422 | SHAMPOO | 10 mg | TOPICAL | OTC Monograph Drug | 12 sections |
| Rugby Anti-Dandruff | HUMAN OTC DRUG LABEL | 1 | 0536-1995 | SHAMPOO | 10 mg | TOPICAL | OTC Monograph Drug | 14 sections |
| Rite AidMEDICATED DANDRUFF | HUMAN OTC DRUG LABEL | 1 | 11822-6101 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 11 sections |
| Rite Aid Moisturizing DandruffMedicated Formula | HUMAN OTC DRUG LABEL | 1 | 11822-6111 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 12 sections |
| RITE AID RENEWALCLINICAL | HUMAN OTC DRUG LABEL | 1 | 11822-6181 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| RITE AID RENEWALCLINICAL | HUMAN OTC DRUG LABEL | 1 | 11822-6181 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| RENEWALMEDICATED | HUMAN OTC DRUG LABEL | 1 | 11822-6191 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| RITE AID RENEWALMEDICATED | HUMAN OTC DRUG LABEL | 1 | 11822-6201 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| RITE AID RENEWAL | HUMAN OTC DRUG LABEL | 1 | 11822-6211 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| RENEWALDANDRUFF MOISTURIZING | HUMAN OTC DRUG LABEL | 1 | 11822-6221 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| Selenium Sulfide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16477-422 | SHAMPOO | 22.50 mg | TOPICAL | unapproved drug other | 17 sections |
| Selenium Sulfide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16477-422 | SHAMPOO | 22.50 mg | TOPICAL | unapproved drug other | 17 sections |
| Selenium Sulfide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16477-423 | SHAMPOO | 23 mg | TOPICAL | unapproved drug other | 17 sections |
| Selenium Sulfide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16477-423 | SHAMPOO | 23 mg | TOPICAL | unapproved drug other | 17 sections |
| ANTIDANDRUFF MEDICATED | HUMAN OTC DRUG LABEL | 1 | 21130-610 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 9 sections |
| SAFEWAYMEDICATED DANDRUFF | HUMAN OTC DRUG LABEL | 1 | 21130-617 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 12 sections |
| SAFEWAY CAREMEDICATED DANDRUFF | HUMAN OTC DRUG LABEL | 1 | 21130-619 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| SAFEWAY | HUMAN OTC DRUG LABEL | 1 | 21130-620 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| SELENIUM SULFIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24470-960 | SHAMPOO | 23 mg | TOPICAL | unapproved drug other | 12 sections |
| KROGERMEDICATED DANDRUFF | HUMAN OTC DRUG LABEL | 1 | 30142-519 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 13 sections |
| TopCareMEDICATED DANDRUFF | HUMAN OTC DRUG LABEL | 1 | 36800-610 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 11 sections |
| TOPCAREGENTLE DANDRUFF CLINICAL STRENGTH | HUMAN OTC DRUG LABEL | 1 | 36800-618 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 11 sections |
| TOPCAREMEDICATED DANDRUFF | HUMAN OTC DRUG LABEL | 1 | 36800-719 | LIQUID | 10 mg | TOPICAL | OTC monograph final | 12 sections |
| HEB Dandruff | HUMAN OTC DRUG LABEL | 1 | 37808-613 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 11 sections |
| Dandruff | HUMAN OTC DRUG LABEL | 1 | 37808-816 | SHAMPOO | 10 mg | TOPICAL | OTC Monograph Drug | 14 sections |
| EQUALINEMEDICATED DANDRUFF | HUMAN OTC DRUG LABEL | 1 | 41163-610 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 11 sections |
| Equaline Moisturizing DandruffMedicated Formula | HUMAN OTC DRUG LABEL | 1 | 41163-611 | SHAMPOO | 1 mL | TOPICAL | OTC monograph final | 12 sections |