selenium sulfide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
4274 7488-56-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • selenium sulfide
  • selenium disulfide
  • Molecular weight: 143.09
  • Formula: S2Se
  • CLOGP: 0.54
  • LIPINSKI: None
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS:
  • ROTB: 0
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT1,AKT2,AKT3,ALK,AURKA,AURKB,AURKC,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK1,CDK2,CDK4,CDK5,CDK9,CHEK1,CSF1R,DDR1,DYRK1B,DYRK3,EGFR,EIF2AK3,EPHB4,ERBB2,FLT1,FLT3,FLT4,GRK2,GSK3B,HIPK2,IKBKB,ITK,JAK1,JAK2,JAK3,KDR,MAP2K6,MAP3K1,MAP3K10,MAP3K14,MAP3K2,MAP3K21,MAP3K3,MAP3K7,MAP4K1,MAP4K3,MAPK1,MAPK10,MAPK12,MAPK7,MAPK8,MAPK9,MAPKAPK2,MARK4,MELK,MET,MTOR,NTRK2,PAK4,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIM1,PIM2,PIM3,PLK1,PRKCD,PRKDC,SGK1,SIK2,SIK3,STK10,STK33,SYK,TEK,TGFBR1,TTK,ULK1,ULK2 88
kinase-selectivity-class ACVR2A,ACVR2B,AXL,BRAF,CDK4,CDK9,DYRK1A,DYRK1B,DYRK3,EIF2AK3,EPHB4,ERBB2,GRK2,GSK3B,HIPK2,IKBKB,JAK2,MAP2K3,MAP2K6,MAP3K14,MAPK12,MAPK7,PIK3CB,PIM3,PRKDC,STK33,SYK,TEK,TTK,UHMK1 30
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

DateAgencyCompanyOrphan
May 17, 1951 FDA CHATTEM

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Lactobacillus test positive 26.18 25.76 3 481 38 110588777

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC D01AE13 DERMATOLOGICALS
ANTIFUNGALS FOR DERMATOLOGICAL USE
ANTIFUNGALS FOR TOPICAL USE
Other antifungals for topical use
MeSH PA D003879 Dermatologic Agents
CHEBI has role CHEBI:35718 antifungal agent
CHEBI has role CHEBI:50177 dermatologic drug

Related Drugs by ATC class:

D01AE Other antifungals for topical use 23 drugs
2-(4-chlorphenoxy)-ethanolamorolfinebromochlorosalicylanilidebutenafinechlorphenesin carbamateciclopiroxdimazoleethyl hydroxybenzoateflucytosinehaloproginliranaftatemethylrosaniline show all 23 →

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Seborrheic dermatitis indication 50563003 DOID:8741
Pityriasis versicolor indication 56454009 DOID:9060
Pityriasis simplex indication 200767005
Distinctive exudative discoid AND lichenoid chronic dermatosis of Sulzberger and Garbe contraindication 41580004
Inflammatory dermatosis contraindication 703938007




🐶 Veterinary Drug Use

SpeciesUseRelation
Dogs Cleansing shampoo Indication
Dogs Removing skin debris associated with dry eczema, seborrhea, and nonspecific dermatoses Indication

🐶 Veterinary products

ProductApplicantIngredients
Seleen Suspension Boehringer lngelheim Animal Health USA Inc. 1
SE S2 Shampoo Intervet Inc. 1
Dandrex Farnam Companies Inc. 1

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018219 VUID
N0000179237 NUI
D05815 KEGG_DRUG
4018219 VANDF
C0074281 UMLSCUI
CHEBI:135934 CHEBI
CHEMBL1200680 ChEMBL_ID
DB00971 DRUGBANK_ID
C025698 MESH_SUPPLEMENTAL_RECORD_UI
Z69D9E381Q UNII
24011 PUBCHEM_CID
36345 RXNORM
1565 MMSL
5451 MMSL
002005 NDDF
018124 NDDF
58292001 SNOMEDCT_US
768430000 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Walgreens Dandruff and Conditioner Cleansing and ConditioningAnti-dandruff HUMAN OTC DRUG LABEL 1 0363-4136 SHAMPOO 10 mg TOPICAL OTC Monograph Drug 13 sections
Walgreens Dandruff Maximum StrengthAnti-dandruff HUMAN OTC DRUG LABEL 1 0363-4139 SHAMPOO 10 mg TOPICAL OTC Monograph Drug 13 sections
Walgreens Dandruff With Menthol/Selenium SulfideAnti-dandruff, anti-seborrheic dermatitis, anti-psoriasis HUMAN OTC DRUG LABEL 1 0363-4902 SHAMPOO 10 mg TOPICAL OTC Monograph Drug 14 sections
Walgreens Clinical Strength Medicated DandruffAnti-dandruff, Anti-seborrheic dermatitis HUMAN OTC DRUG LABEL 1 0363-9422 SHAMPOO 10 mg TOPICAL OTC Monograph Drug 12 sections
Rugby Anti-Dandruff HUMAN OTC DRUG LABEL 1 0536-1995 SHAMPOO 10 mg TOPICAL OTC Monograph Drug 14 sections
Rite AidMEDICATED DANDRUFF HUMAN OTC DRUG LABEL 1 11822-6101 SHAMPOO 1 mL TOPICAL OTC monograph final 11 sections
Rite Aid Moisturizing DandruffMedicated Formula HUMAN OTC DRUG LABEL 1 11822-6111 SHAMPOO 1 mL TOPICAL OTC monograph final 12 sections
RITE AID RENEWALCLINICAL HUMAN OTC DRUG LABEL 1 11822-6181 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
RITE AID RENEWALCLINICAL HUMAN OTC DRUG LABEL 1 11822-6181 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
RENEWALMEDICATED HUMAN OTC DRUG LABEL 1 11822-6191 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
RITE AID RENEWALMEDICATED HUMAN OTC DRUG LABEL 1 11822-6201 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
RITE AID RENEWAL HUMAN OTC DRUG LABEL 1 11822-6211 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
RENEWALDANDRUFF MOISTURIZING HUMAN OTC DRUG LABEL 1 11822-6221 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
Selenium Sulfide HUMAN PRESCRIPTION DRUG LABEL 1 16477-422 SHAMPOO 22.50 mg TOPICAL unapproved drug other 17 sections
Selenium Sulfide HUMAN PRESCRIPTION DRUG LABEL 1 16477-422 SHAMPOO 22.50 mg TOPICAL unapproved drug other 17 sections
Selenium Sulfide HUMAN PRESCRIPTION DRUG LABEL 1 16477-423 SHAMPOO 23 mg TOPICAL unapproved drug other 17 sections
Selenium Sulfide HUMAN PRESCRIPTION DRUG LABEL 1 16477-423 SHAMPOO 23 mg TOPICAL unapproved drug other 17 sections
ANTIDANDRUFF MEDICATED HUMAN OTC DRUG LABEL 1 21130-610 SHAMPOO 1 mL TOPICAL OTC monograph final 9 sections
SAFEWAYMEDICATED DANDRUFF HUMAN OTC DRUG LABEL 1 21130-617 SHAMPOO 1 mL TOPICAL OTC monograph final 12 sections
SAFEWAY CAREMEDICATED DANDRUFF HUMAN OTC DRUG LABEL 1 21130-619 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
SAFEWAY HUMAN OTC DRUG LABEL 1 21130-620 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
SELENIUM SULFIDE HUMAN PRESCRIPTION DRUG LABEL 1 24470-960 SHAMPOO 23 mg TOPICAL unapproved drug other 12 sections
KROGERMEDICATED DANDRUFF HUMAN OTC DRUG LABEL 1 30142-519 LIQUID 10 mg TOPICAL OTC monograph final 13 sections
TopCareMEDICATED DANDRUFF HUMAN OTC DRUG LABEL 1 36800-610 SHAMPOO 1 mL TOPICAL OTC monograph final 11 sections
TOPCAREGENTLE DANDRUFF CLINICAL STRENGTH HUMAN OTC DRUG LABEL 1 36800-618 LIQUID 10 mg TOPICAL OTC monograph final 11 sections
TOPCAREMEDICATED DANDRUFF HUMAN OTC DRUG LABEL 1 36800-719 LIQUID 10 mg TOPICAL OTC monograph final 12 sections
HEB Dandruff HUMAN OTC DRUG LABEL 1 37808-613 SHAMPOO 1 mL TOPICAL OTC monograph final 11 sections
Dandruff HUMAN OTC DRUG LABEL 1 37808-816 SHAMPOO 10 mg TOPICAL OTC Monograph Drug 14 sections
EQUALINEMEDICATED DANDRUFF HUMAN OTC DRUG LABEL 1 41163-610 SHAMPOO 1 mL TOPICAL OTC monograph final 11 sections
Equaline Moisturizing DandruffMedicated Formula HUMAN OTC DRUG LABEL 1 41163-611 SHAMPOO 1 mL TOPICAL OTC monograph final 12 sections