sodium phosphate, monobasic 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4271	7558-80-7

Description:

Molecule	Description
Synonyms: sodium phosphate, monobasic dihydrogen monosodium phosphate phosphoric acid monosodium salt monobasic sodium phosphate monosodium dihydrogen orthophosphate	Molecular weight: 119.98 Formula: H2NaO4P CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: ALOGS: ROTB: None

Molecule

Description

Synonyms:

sodium phosphate, monobasic
dihydrogen monosodium phosphate
phosphoric acid monosodium salt
monobasic sodium phosphate
monosodium dihydrogen orthophosphate

Molecular weight: 119.98
Formula: H2NaO4P
CLOGP:
LIPINSKI: None
HAC: None
HDO: None
TPSA:
ALOGS:
ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Intestinal pseudo-obstruction	85.86	25.90	16	1909	896	63486201
Cytokine release syndrome	57.14	25.90	20	1905	14294	63472803
Delirium	38.25	25.90	22	1903	50519	63436578
Loss of bladder sensation	34.69	25.90	5	1920	54	63487043
Mutism	32.76	25.90	8	1917	1622	63485475
Encephalopathy	32.43	25.90	18	1907	38602	63448495
Food refusal	31.63	25.90	6	1919	369	63486728
Cholelithiasis	30.27	25.90	18	1907	43907	63443190
Vomiting	28.24	25.90	56	1869	559561	62927536
Urinary retention	27.86	25.90	15	1910	30286	63456811

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FDA Adverse Event Reporting System (Male)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Appendicolith	507.13	36.88	134	4523	8467	34943807
Appendicitis	439.39	36.88	135	4522	14672	34937602
Cardiogenic shock	369.10	36.88	137	4520	26481	34925793
Stress	348.07	36.88	136	4521	30211	34922063
Ascites	291.92	36.88	136	4521	46435	34905839
Ventricular fibrillation	277.62	36.88	107	4550	22847	34929427
Abdominal distension	274.08	36.88	140	4517	58352	34893922
Multiple organ dysfunction syndrome	233.44	36.88	138	4519	76428	34875846
Blood phosphorus increased	231.21	36.88	71	4586	7650	34944624
Hyponatraemia	228.74	36.88	140	4517	82551	34869723

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FDA Adverse Event Reporting System (Geriatric)

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MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Appendicolith	564.79	25.55	133	6499	8418	79729338
Appendicitis	451.97	25.55	134	6498	20660	79717096
Cardiogenic shock	381.91	25.55	140	6492	41774	79695982
Ventricular fibrillation	291.99	25.55	107	6525	31819	79705937
Ascites	289.71	25.55	136	6496	75426	79662330
Stress	279.90	25.55	135	6497	79477	79658279
Abdominal distension	260.22	25.55	147	6485	119503	79618253
Blood phosphorus increased	247.98	25.55	72	6560	10275	79727481
Multiple organ dysfunction syndrome	243.41	25.55	141	6491	120105	79617651
Sepsis	196.51	25.55	169	6463	269259	79468497

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FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

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Disease	Relation	SNOMED_ID	DOID
Hypophosphatemia	indication	4996001
Constipation	indication	14760008	DOID:2089
Urinary tract infectious disease	indication	68566005
Incomplete passage of stool	indication	249515001
Calcium renal calculus	indication	427649000
Osteopenia of prematurity	off-label use	276703007
Fluid volume disorder	contraindication	1860003
Anuria	contraindication	2472002	DOID:2983
Gastritis	contraindication	4556007	DOID:4029
Hypocalcemia	contraindication	5291005

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🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

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ID	Source
000761	NDDF
002336	NDDF
116124008	SNOMEDCT_US
235496	RXNORM
23672064	PUBCHEM_CID
4017619	VANDF
4018072	VUID
4018072	VANDF
5208	MMSL
5469	MMSL

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Pharmaceutical products:

None