All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

zinc acetate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4269	557-34-6

Description:

Molecule	Description
Synonyms: zinc acetate anhydrous zinc acetate dihydrate wilzin zinc acetate zinc diacetate zinc acetate hydrate nobelzin	A salt produced by the reaction of zinc oxide with acetic acid and used as an astringent, styptic, and emetic. Molecular weight: 183.47 Formula: C4H6O4Zn CLOGP: LIPINSKI: None HAC: None HDO: None TPSA: 40.13 ALOGS: ROTB: None

Drug dosage:

Dose	Unit	Route
0.15	g	O

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
Feb. 22, 1980	FDA	ARMOUR PHARM
Jan. 22, 2021	PMDA	NOBELPHARMA Co., Ltd

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Anosmia	99.49	21.62	26	1931	6834	63480231
Ageusia	46.28	21.62	17	1940	13711	63473354
Urine odour abnormal	41.71	21.62	13	1944	6376	63480689
Hepatic enzyme abnormal	29.49	21.62	10	1947	6382	63480683
Urine abnormality	28.58	21.62	10	1947	7009	63480056
Corneal neovascularisation	24.05	21.62	4	1953	113	63486952
Bone erosion	22.61	21.62	11	1946	17706	63469359
Hyposmia	22.21	21.62	5	1952	702	63486363
Wheelchair user	21.93	21.62	8	1949	6311	63480754

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Anosmia	51.21	24.99	13	808	4011	34952099
Mental impairment	31.28	24.99	11	810	10311	34945799
Product substitution issue	27.71	24.99	10	811	10085	34946025
Proteus infection	26.70	24.99	6	815	1100	34955010

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Anosmia	129.01	21.26	33	2195	8811	79733349
Ageusia	48.36	21.26	18	2210	16614	79725546
Urine odour abnormal	30.64	21.26	10	2218	6263	79735897
Corneal neovascularisation	23.10	21.26	4	2224	160	79742000
Mental impairment	22.88	21.26	11	2217	19025	79723135
Blood copper decreased	22.77	21.26	3	2225	17	79742143
Hyposmia	22.30	21.26	5	2223	760	79741400
Proteus infection	21.78	21.26	6	2222	2112	79740048

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	A16AX05	ALIMENTARY TRACT AND METABOLISM OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS Various alimentary tract and metabolism products
CHEBI has role	CHEBI:74783	adstringent

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Otitis externa	indication	3135009
Proctitis	indication	3951002	DOID:3127
Wound	indication	13924000
Burn injury	indication	48333001
Hemorrhoids	indication	70153002	DOID:9746
Rectal pain	indication	77880009
Wilson's disease	indication	88518009
Diaper rash	indication	91487003
Hypozincemia	indication	238124008
Eruption of skin	indication	271807003	DOID:0050486
Skin irritation	indication	367466007
Arthropod bite wound	indication	409985002
Itching of skin	indication	418363000
Itching of ear	indication	699392007
Otalgia	off-label use	16001004
Impacted cerumen	off-label use	18070006
Hypocupremia	contraindication	19577007
Perforation of tympanic membrane	contraindication	60442001
Open wound	contraindication	125643001
Infective otitis media	contraindication	312218008
Denuded skin	contraindication	418242004
Porphyria	contraindication	418470004

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
4021033	VUID
N0000148498	NUI
4021033	VANDF
C0149368	UMLSCUI
CHEBI:62984	CHEBI
CHEMBL3184986	ChEMBL_ID
CHEMBL1200928	ChEMBL_ID
D019345	MESH_DESCRIPTOR_UI
DB14487	DRUGBANK_ID
FM5526K07A	UNII
11192	PUBCHEM_CID
1299637	RXNORM
27914	MMSL
5706	MMSL
72545	MMSL
NOCODE	MMSL
d04123	MMSL
003862	NDDF
003863	NDDF
015397	NDDF
395952003	SNOMEDCT_US
412376004	SNOMEDCT_US
5970-45-6	SECONDARY_CAS_RN

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
good sense itch relief	HUMAN OTC DRUG LABEL	2	0113-0622	CREAM	0.10 g	TOPICAL	OTC monograph not final	14 sections
Caladryl Clear	HUMAN OTC DRUG LABEL	2	0187-5466	LOTION	1 mg	TOPICAL	OTC monograph final	14 sections
WAL- DRYL ITCH RELIEF	HUMAN OTC DRUG LABEL	2	0363-0121	CREAM	1 mg	TOPICAL	OTC MONOGRAPH NOT FINAL	15 sections
Wal-dryl	HUMAN OTC DRUG LABEL	2	0363-0122	CREAM	0.10 mg	TOPICAL	OTC MONOGRAPH NOT FINAL	13 sections
Diphenhydramine HCl and Zinc Acetate	HUMAN OTC DRUG LABEL	2	0363-0215	SPRAY	0.08 g	TOPICAL	OTC monograph not final	15 sections
Diphenhydramine HCl and Zinc Acetate	HUMAN OTC DRUG LABEL	2	0363-0215	SPRAY	0.08 g	TOPICAL	OTC monograph not final	15 sections
Anti-Itch Wal-Dryl	HUMAN OTC DRUG LABEL	2	0363-0295	SPRAY	0.10 kg	TOPICAL	OTC monograph not final	14 sections
Anti-Itch Wal-Dryl	HUMAN OTC DRUG LABEL	2	0363-0295	SPRAY	0.10 kg	TOPICAL	OTC monograph not final	14 sections
WALGREENS ANTI ITCH	HUMAN OTC DRUG LABEL	2	0363-1411	CREAM	0.10 g	TOPICAL	OTC monograph final	13 sections
EXTRA STRENGTH WAL-DRYL ITCH RELIEF	HUMAN OTC DRUG LABEL	2	0363-2177	SPRAY	1 mg	TOPICAL	OTC monograph not final	15 sections
Walgreens Anti Itch Cream	HUMAN OTC DRUG LABEL	2	0363-2315	CREAM	1 mg	TOPICAL	OTC monograph final	10 sections
Walgreens Original Strength Anti Itch	HUMAN OTC DRUG LABEL	2	0363-4115	CREAM	0.10 g	TOPICAL	OTC monograph not final	15 sections
Clear Anti-Itch	HUMAN OTC DRUG LABEL	2	0363-9115	LOTION	1 mg	TOPICAL	OTC monograph final	13 sections
Clear Anti-Itch	HUMAN OTC DRUG LABEL	2	0363-9115	LOTION	0.10 mg	TOPICAL	OTC monograph final	13 sections
Clear Anti-Itch	HUMAN OTC DRUG LABEL	2	0363-9115	LOTION	0.10 mg	TOPICAL	OTC monograph final	13 sections
Humco Calaclear	HUMAN OTC DRUG LABEL	2	0395-0400	LOTION	1 mg	TOPICAL	OTC monograph final	12 sections
Humco Calaclear	HUMAN OTC DRUG LABEL	2	0395-0400	LOTION	1 mg	TOPICAL	OTC monograph final	12 sections
Calaclear	HUMAN OTC DRUG LABEL	2	0395-9108	LOTION	1 mg	TOPICAL	OTC monograph final	12 sections
Rugby Caldyphen Clear	HUMAN OTC DRUG LABEL	2	0536-1269	LOTION	1 mg	TOPICAL	OTC monograph final	8 sections
Rugby Caldyphen Clear	HUMAN OTC DRUG LABEL	2	0536-1269	LOTION	1 mg	TOPICAL	OTC monograph final	8 sections
Clear Anti Itch	HUMAN OTC DRUG LABEL	2	0869-0218	LOTION	1 mg	TOPICAL	OTC monograph final	12 sections
Clear Anti Itch	HUMAN OTC DRUG LABEL	2	0869-0218	LOTION	1 mg	TOPICAL	OTC monograph final	12 sections
Itch Relief	HUMAN OTC DRUG LABEL	2	0869-0295	SPRAY	882 mg	TOPICAL	OTC monograph not final	14 sections
Itch Relief	HUMAN OTC DRUG LABEL	2	0869-0295	SPRAY	882 mg	TOPICAL	OTC monograph not final	14 sections
Banophen	HUMAN OTC DRUG LABEL	2	0904-5354	CREAM	0.10 g	TOPICAL	OTC monograph not final	14 sections
Clear Anti Itch	HUMAN OTC DRUG LABEL	2	0904-7760	LOTION	1 mg	TOPICAL	OTC monograph final	12 sections
Blistex Ivarest Poison Ivy Itch	HUMAN OTC DRUG LABEL	2	10157-2100	SPRAY	0.12 g	TOPICAL	OTC MONOGRAPH FINAL	12 sections
Clear Anti-Itch	HUMAN OTC DRUG LABEL	2	11344-218	LOTION	1 mg	TOPICAL	OTC monograph not final	12 sections
Weeks and Leo Extra Strength Itch Stopping	HUMAN OTC DRUG LABEL	2	11383-258	CREAM	1 mg	TOPICAL	OTC monograph not final	13 sections
Dr. Sheffield Anti Itch Cream	HUMAN OTC DRUG LABEL	2	11527-069	CREAM	1 mg	TOPICAL	OTC monograph final	9 sections