Stem definition | Drug id | CAS RN |
---|---|---|
4251 | 7727-37-9 |
None
None
Date | Agency | Company | Orphan |
---|---|---|---|
None | FDA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Dyspnoea | 939.53 | 11.76 | 1917 | 54481 | 590660 | 55645009 |
Pulmonary arterial hypertension | 674.91 | 11.76 | 386 | 56012 | 26117 | 56209552 |
Oxygen saturation decreased | 606.70 | 11.76 | 555 | 55843 | 78512 | 56157157 |
Pulmonary hypertension | 519.66 | 11.76 | 366 | 56032 | 35578 | 56200091 |
Oxygen consumption increased | 468.27 | 11.76 | 165 | 56233 | 3466 | 56232203 |
Right ventricular failure | 445.06 | 11.76 | 249 | 56149 | 16130 | 56219539 |
Dyspnoea exertional | 400.05 | 11.76 | 374 | 56024 | 54315 | 56181354 |
Fluid retention | 386.31 | 11.76 | 365 | 56033 | 53713 | 56181956 |
Drug ineffective | 351.47 | 11.76 | 248 | 56150 | 918741 | 55316928 |
Chronic obstructive pulmonary disease | 325.90 | 11.76 | 342 | 56056 | 57073 | 56178596 |
Hypoxia | 316.59 | 11.76 | 327 | 56071 | 53570 | 56182099 |
Rheumatoid arthritis | 275.47 | 11.76 | 31 | 56367 | 382573 | 55853096 |
Respiratory failure | 272.98 | 11.76 | 402 | 55996 | 94660 | 56141009 |
Hypervolaemia | 218.90 | 11.76 | 194 | 56204 | 26264 | 56209405 |
Oxygen therapy | 216.36 | 11.76 | 79 | 56319 | 1844 | 56233825 |
Pneumonia | 206.57 | 11.76 | 880 | 55518 | 406218 | 55829451 |
Transfusion | 205.36 | 11.76 | 142 | 56256 | 13378 | 56222291 |
Pain in jaw | 174.70 | 11.76 | 208 | 56190 | 39828 | 56195841 |
Nasal congestion | 166.92 | 11.76 | 242 | 56156 | 56128 | 56179541 |
Oedema peripheral | 160.06 | 11.76 | 454 | 55944 | 170800 | 56064869 |
Acute respiratory failure | 153.66 | 11.76 | 172 | 56226 | 30822 | 56204847 |
Arthropathy | 141.99 | 11.76 | 17 | 56381 | 200258 | 56035411 |
Treatment failure | 141.59 | 11.76 | 7 | 56391 | 170385 | 56065284 |
Cardiac failure | 139.51 | 11.76 | 275 | 56123 | 81818 | 56153851 |
Alopecia | 139.14 | 11.76 | 60 | 56338 | 293398 | 55942271 |
Cough | 136.17 | 11.76 | 568 | 55830 | 259393 | 55976276 |
Productive cough | 129.51 | 11.76 | 215 | 56183 | 56017 | 56179652 |
Glossodynia | 127.51 | 11.76 | 6 | 56392 | 152452 | 56083217 |
Therapeutic product effect decreased | 126.20 | 11.76 | 12 | 56386 | 169440 | 56066229 |
Drug intolerance | 124.16 | 11.76 | 55 | 56343 | 264763 | 55970906 |
Chest pain | 117.32 | 11.76 | 437 | 55961 | 189360 | 56046309 |
Pulmonary oedema | 117.04 | 11.76 | 195 | 56203 | 50948 | 56184721 |
Joint swelling | 116.98 | 11.76 | 73 | 56325 | 289727 | 55945942 |
Hand deformity | 116.83 | 11.76 | 4 | 56394 | 134488 | 56101181 |
Pulmonary arterial pressure increased | 115.47 | 11.76 | 60 | 56338 | 3345 | 56232324 |
Rash | 111.21 | 11.76 | 203 | 56195 | 492844 | 55742825 |
Toxicity to various agents | 111.12 | 11.76 | 43 | 56355 | 224521 | 56011148 |
Oedema | 110.78 | 11.76 | 250 | 56148 | 81670 | 56153999 |
Concomitant disease aggravated | 110.65 | 11.76 | 81 | 56317 | 8345 | 56227324 |
Systemic lupus erythematosus | 110.26 | 11.76 | 23 | 56375 | 180055 | 56055614 |
Drug hypersensitivity | 108.77 | 11.76 | 71 | 56327 | 275134 | 55960535 |
Epistaxis | 94.50 | 11.76 | 208 | 56190 | 66815 | 56168854 |
Catheter site erythema | 92.20 | 11.76 | 55 | 56343 | 4015 | 56231654 |
Catheter site pruritus | 90.62 | 11.76 | 43 | 56355 | 1969 | 56233700 |
Haemoptysis | 84.43 | 11.76 | 118 | 56280 | 26442 | 56209227 |
Syncope | 84.12 | 11.76 | 269 | 56129 | 107930 | 56127739 |
Lung transplant | 83.28 | 11.76 | 46 | 56352 | 2901 | 56232768 |
Musculoskeletal stiffness | 80.30 | 11.76 | 28 | 56370 | 155979 | 56079690 |
Hypercapnia | 78.49 | 11.76 | 54 | 56344 | 5042 | 56230627 |
Blood pressure decreased | 77.36 | 11.76 | 178 | 56220 | 58872 | 56176797 |
Catheter management | 76.83 | 11.76 | 43 | 56355 | 2783 | 56232886 |
Discomfort | 75.48 | 11.76 | 24 | 56374 | 141737 | 56093932 |
Headache | 75.44 | 11.76 | 873 | 55525 | 558171 | 55677498 |
Brain natriuretic peptide increased | 74.97 | 11.76 | 51 | 56347 | 4675 | 56230994 |
Hepatic enzyme increased | 73.58 | 11.76 | 40 | 56358 | 171344 | 56064325 |
Pericarditis | 72.97 | 11.76 | 11 | 56387 | 108912 | 56126757 |
Cardiac failure congestive | 72.69 | 11.76 | 223 | 56175 | 87497 | 56148172 |
Dependence on oxygen therapy | 72.44 | 11.76 | 23 | 56375 | 345 | 56235324 |
Scleroderma | 72.37 | 11.76 | 51 | 56347 | 4950 | 56230719 |
Arthralgia | 70.44 | 11.76 | 262 | 56136 | 501407 | 55734262 |
Hypersensitivity | 66.63 | 11.76 | 96 | 56302 | 256312 | 55979357 |
Wound | 66.30 | 11.76 | 28 | 56370 | 138776 | 56096893 |
Hypotension | 65.85 | 11.76 | 453 | 55945 | 250055 | 55985614 |
Off label use | 65.40 | 11.76 | 311 | 56087 | 555869 | 55679800 |
Infusion related reaction | 62.82 | 11.76 | 70 | 56328 | 208861 | 56026808 |
Catheterisation cardiac | 62.80 | 11.76 | 44 | 56354 | 4231 | 56231438 |
Psoriatic arthropathy | 61.57 | 11.76 | 3 | 56395 | 74005 | 56161664 |
Maternal exposure during pregnancy | 60.93 | 11.76 | 60 | 56338 | 189493 | 56046176 |
Stomatitis | 59.93 | 11.76 | 23 | 56375 | 120787 | 56114882 |
Device alarm issue | 59.84 | 11.76 | 29 | 56369 | 1392 | 56234277 |
Pain | 59.04 | 11.76 | 406 | 55992 | 662778 | 55572891 |
Product use issue | 58.52 | 11.76 | 60 | 56338 | 185981 | 56049688 |
Pleural effusion | 57.96 | 11.76 | 203 | 56195 | 85277 | 56150392 |
Palpitations | 57.77 | 11.76 | 225 | 56173 | 99447 | 56136222 |
Neutropenia | 56.93 | 11.76 | 45 | 56353 | 158122 | 56077547 |
Drug abuse | 55.42 | 11.76 | 3 | 56395 | 67607 | 56168062 |
Dizziness | 55.41 | 11.76 | 598 | 55800 | 375542 | 55860127 |
Death | 55.10 | 11.76 | 553 | 55845 | 340873 | 55894796 |
Pulmonary veno-occlusive disease | 54.97 | 11.76 | 25 | 56373 | 1038 | 56234631 |
Cyanosis | 54.41 | 11.76 | 73 | 56325 | 15737 | 56219932 |
Cor pulmonale | 53.46 | 11.76 | 30 | 56368 | 1951 | 56233718 |
Unevaluable event | 53.07 | 11.76 | 135 | 56263 | 47552 | 56188117 |
Pericardial effusion | 52.24 | 11.76 | 96 | 56302 | 27079 | 56208590 |
Flushing | 51.49 | 11.76 | 171 | 56227 | 69929 | 56165740 |
Catheter site pain | 51.30 | 11.76 | 39 | 56359 | 4254 | 56231415 |
Malaise | 47.91 | 11.76 | 571 | 55827 | 367289 | 55868380 |
Device related infection | 46.82 | 11.76 | 81 | 56317 | 21799 | 56213870 |
Catheter site discharge | 46.72 | 11.76 | 27 | 56371 | 1858 | 56233811 |
Therapeutic product effect incomplete | 46.59 | 11.76 | 24 | 56374 | 106007 | 56129662 |
Pruritus | 45.90 | 11.76 | 163 | 56235 | 316460 | 55919209 |
Blister | 45.87 | 11.76 | 26 | 56372 | 108861 | 56126808 |
Psoriasis | 45.38 | 11.76 | 18 | 56380 | 92674 | 56142995 |
Catheter site infection | 45.30 | 11.76 | 37 | 56361 | 4477 | 56231192 |
Exercise tolerance decreased | 45.13 | 11.76 | 39 | 56359 | 5099 | 56230570 |
Chest discomfort | 44.74 | 11.76 | 207 | 56191 | 98650 | 56137019 |
Dyspnoea at rest | 44.15 | 11.76 | 34 | 56364 | 3779 | 56231890 |
Impaired healing | 43.96 | 11.76 | 16 | 56382 | 86825 | 56148844 |
Chronic respiratory failure | 43.25 | 11.76 | 25 | 56373 | 1721 | 56233948 |
Injection site erythema | 43.23 | 11.76 | 12 | 56386 | 77436 | 56158233 |
Intentional overdose | 43.13 | 11.76 | 8 | 56390 | 68109 | 56167560 |
Orthopnoea | 42.89 | 11.76 | 40 | 56358 | 5776 | 56229893 |
Transplant evaluation | 42.37 | 11.76 | 21 | 56377 | 1059 | 56234610 |
Respiratory distress | 42.05 | 11.76 | 96 | 56302 | 31571 | 56204098 |
Bronchitis | 41.48 | 11.76 | 222 | 56176 | 112089 | 56123580 |
Irritable bowel syndrome | 41.34 | 11.76 | 9 | 56389 | 68449 | 56167220 |
Injection site pain | 41.28 | 11.76 | 34 | 56364 | 117084 | 56118585 |
Suicide attempt | 40.72 | 11.76 | 5 | 56393 | 57831 | 56177838 |
Left ventricular failure | 40.04 | 11.76 | 36 | 56362 | 4960 | 56230709 |
Catheter site rash | 39.63 | 11.76 | 18 | 56380 | 745 | 56234924 |
Exposure during pregnancy | 39.53 | 11.76 | 47 | 56351 | 136295 | 56099374 |
Hospitalisation | 39.21 | 11.76 | 164 | 56234 | 74836 | 56160833 |
Infusion site pain | 39.13 | 11.76 | 58 | 56340 | 13704 | 56221965 |
Blood cholesterol increased | 39.13 | 11.76 | 12 | 56386 | 72567 | 56163102 |
Lung disorder | 38.35 | 11.76 | 128 | 56270 | 52469 | 56183200 |
Pulmonary arterial pressure abnormal | 37.39 | 11.76 | 15 | 56383 | 455 | 56235214 |
Pulmonary hypertensive crisis | 36.35 | 11.76 | 12 | 56386 | 205 | 56235464 |
Nasal dryness | 35.70 | 11.76 | 30 | 56368 | 3776 | 56231893 |
Abdominal distension | 35.45 | 11.76 | 163 | 56235 | 77463 | 56158206 |
Presyncope | 34.46 | 11.76 | 78 | 56320 | 25504 | 56210165 |
Overdose | 33.41 | 11.76 | 34 | 56364 | 105796 | 56129873 |
Urticaria | 32.98 | 11.76 | 59 | 56339 | 144617 | 56091052 |
Aspiration pleural cavity | 32.97 | 11.76 | 16 | 56382 | 770 | 56234899 |
Atrial flutter | 32.57 | 11.76 | 43 | 56355 | 9126 | 56226543 |
Pulmonary congestion | 32.33 | 11.76 | 58 | 56340 | 16057 | 56219612 |
Injection site reaction | 32.15 | 11.76 | 7 | 56391 | 53240 | 56182429 |
Oxygen saturation abnormal | 31.76 | 11.76 | 25 | 56373 | 2869 | 56232800 |
Bladder agenesis | 31.74 | 11.76 | 10 | 56388 | 146 | 56235523 |
Ascites | 31.59 | 11.76 | 96 | 56302 | 37448 | 56198221 |
Interstitial lung disease | 31.58 | 11.76 | 127 | 56271 | 56936 | 56178733 |
Catheter placement | 31.48 | 11.76 | 22 | 56376 | 2106 | 56233563 |
Air embolism | 31.34 | 11.76 | 11 | 56387 | 228 | 56235441 |
Oxygen consumption | 31.32 | 11.76 | 9 | 56389 | 94 | 56235575 |
Cloacal exstrophy | 31.31 | 11.76 | 10 | 56388 | 153 | 56235516 |
Genitalia external ambiguous | 31.31 | 11.76 | 10 | 56388 | 153 | 56235516 |
Emphysema | 31.22 | 11.76 | 44 | 56354 | 9932 | 56225737 |
Cardiac disorder | 31.11 | 11.76 | 109 | 56289 | 45778 | 56189891 |
Respiratory tract infection | 31.07 | 11.76 | 93 | 56305 | 35978 | 56199691 |
Febrile neutropenia | 31.00 | 11.76 | 36 | 56362 | 105509 | 56130160 |
Congenital ectopic bladder | 30.98 | 11.76 | 9 | 56389 | 98 | 56235571 |
Cardiac arrest | 30.77 | 11.76 | 169 | 56229 | 86145 | 56149524 |
Mobility decreased | 29.90 | 11.76 | 33 | 56365 | 98958 | 56136711 |
Thermal burn | 29.88 | 11.76 | 32 | 56366 | 5453 | 56230216 |
Cardiac pacemaker insertion | 29.77 | 11.76 | 27 | 56371 | 3763 | 56231906 |
Condition aggravated | 29.76 | 11.76 | 498 | 55900 | 344400 | 55891269 |
Meconium stain | 29.40 | 11.76 | 10 | 56388 | 188 | 56235481 |
Subcutaneous emphysema | 29.34 | 11.76 | 15 | 56383 | 808 | 56234861 |
Cardiac failure acute | 29.06 | 11.76 | 40 | 56358 | 8833 | 56226836 |
Gastrointestinal disorder congenital | 28.59 | 11.76 | 9 | 56389 | 131 | 56235538 |
Rales | 28.43 | 11.76 | 44 | 56354 | 10796 | 56224873 |
Device occlusion | 28.42 | 11.76 | 34 | 56364 | 6535 | 56229134 |
Anaemia | 28.34 | 11.76 | 400 | 55998 | 267111 | 55968558 |
Central venous catheterisation | 28.26 | 11.76 | 22 | 56376 | 2485 | 56233184 |
Swelling | 28.10 | 11.76 | 134 | 56264 | 239637 | 55996032 |
Ill-defined disorder | 27.96 | 11.76 | 17 | 56381 | 68526 | 56167143 |
Congenital genital malformation | 27.92 | 11.76 | 9 | 56389 | 142 | 56235527 |
Tethered cord syndrome | 27.73 | 11.76 | 10 | 56388 | 225 | 56235444 |
Gamma-glutamyltransferase increased | 27.72 | 11.76 | 81 | 56317 | 30924 | 56204745 |
Device leakage | 27.59 | 11.76 | 33 | 56365 | 6342 | 56229327 |
Paracentesis | 27.57 | 11.76 | 15 | 56383 | 918 | 56234751 |
Lipodystrophy acquired | 27.31 | 11.76 | 17 | 56381 | 1340 | 56234329 |
Cardiac ablation | 27.19 | 11.76 | 17 | 56381 | 1350 | 56234319 |
Caudal regression syndrome | 26.67 | 11.76 | 9 | 56389 | 165 | 56235504 |
Knee arthroplasty | 26.35 | 11.76 | 6 | 56392 | 44253 | 56191416 |
Atrial fibrillation | 26.25 | 11.76 | 193 | 56205 | 108704 | 56126965 |
Gastrointestinal malformation | 26.13 | 11.76 | 9 | 56389 | 176 | 56235493 |
Leukopenia | 25.74 | 11.76 | 20 | 56378 | 70920 | 56164749 |
Anaesthetic complication | 25.66 | 11.76 | 18 | 56380 | 1734 | 56233935 |
Suicidal ideation | 25.46 | 11.76 | 13 | 56385 | 57729 | 56177940 |
Abdominal discomfort | 25.41 | 11.76 | 168 | 56230 | 277106 | 55958563 |
Intentional product use issue | 25.22 | 11.76 | 38 | 56360 | 99695 | 56135974 |
Pulmonary function test decreased | 25.15 | 11.76 | 24 | 56374 | 3567 | 56232102 |
Lower respiratory tract infection | 25.11 | 11.76 | 48 | 56350 | 114746 | 56120923 |
Catheter site scab | 25.02 | 11.76 | 9 | 56389 | 201 | 56235468 |
N-terminal prohormone brain natriuretic peptide increased | 24.85 | 11.76 | 18 | 56380 | 1824 | 56233845 |
Blood iron decreased | 24.76 | 11.76 | 45 | 56353 | 12582 | 56223087 |
Heart rate increased | 24.49 | 11.76 | 155 | 56243 | 83118 | 56152551 |
Haemoglobin decreased | 24.39 | 11.76 | 223 | 56175 | 133914 | 56101755 |
Liver injury | 24.27 | 11.76 | 6 | 56392 | 41842 | 56193827 |
Product use in unapproved indication | 23.50 | 11.76 | 68 | 56330 | 140754 | 56094915 |
Cognitive disorder | 23.30 | 11.76 | 10 | 56388 | 49123 | 56186546 |
Anal atresia | 22.79 | 11.76 | 10 | 56388 | 381 | 56235288 |
Depression | 22.69 | 11.76 | 98 | 56300 | 180019 | 56055650 |
Rhinorrhoea | 22.60 | 11.76 | 115 | 56283 | 56922 | 56178747 |
Anencephaly | 22.56 | 11.76 | 9 | 56389 | 269 | 56235400 |
Walking distance test abnormal | 22.48 | 11.76 | 11 | 56387 | 539 | 56235130 |
Injection site pruritus | 22.48 | 11.76 | 7 | 56391 | 41924 | 56193745 |
Disease progression | 22.35 | 11.76 | 181 | 56217 | 104992 | 56130677 |
Catheter site swelling | 22.12 | 11.76 | 15 | 56383 | 1368 | 56234301 |
Haematocrit decreased | 22.02 | 11.76 | 84 | 56314 | 36745 | 56198924 |
Sputum discoloured | 22.01 | 11.76 | 46 | 56352 | 14246 | 56221423 |
Neuromuscular blockade | 21.87 | 11.76 | 9 | 56389 | 292 | 56235377 |
Device connection issue | 21.77 | 11.76 | 11 | 56387 | 578 | 56235091 |
Red blood cell sedimentation rate increased | 21.74 | 11.76 | 5 | 56393 | 36618 | 56199051 |
Neural tube defect | 21.70 | 11.76 | 8 | 56390 | 192 | 56235477 |
Congestive hepatopathy | 21.51 | 11.76 | 19 | 56379 | 2557 | 56233112 |
Aspartate aminotransferase increased | 21.41 | 11.76 | 149 | 56249 | 82453 | 56153216 |
Iron deficiency anaemia | 21.27 | 11.76 | 52 | 56346 | 17867 | 56217802 |
Osteoarthritis | 20.88 | 11.76 | 30 | 56368 | 80266 | 56155403 |
Concomitant disease progression | 20.75 | 11.76 | 17 | 56381 | 2065 | 56233604 |
Nocturnal dyspnoea | 20.72 | 11.76 | 13 | 56385 | 1039 | 56234630 |
Adverse drug reaction | 20.46 | 11.76 | 21 | 56377 | 65111 | 56170558 |
Upper respiratory tract inflammation | 20.15 | 11.76 | 18 | 56380 | 2459 | 56233210 |
Stent placement | 19.84 | 11.76 | 21 | 56377 | 3530 | 56232139 |
Infusion site erythema | 19.82 | 11.76 | 35 | 56363 | 9571 | 56226098 |
Cardiomegaly | 19.77 | 11.76 | 48 | 56350 | 16419 | 56219250 |
Pneumothorax | 19.66 | 11.76 | 45 | 56353 | 14822 | 56220847 |
Right ventricular dysfunction | 19.58 | 11.76 | 15 | 56383 | 1654 | 56234015 |
Confusional state | 19.12 | 11.76 | 126 | 56272 | 208029 | 56027640 |
Gastrointestinal disorder | 19.11 | 11.76 | 54 | 56344 | 112648 | 56123021 |
Injection site swelling | 18.93 | 11.76 | 10 | 56388 | 43568 | 56192101 |
Pulmonary artery banding | 18.63 | 11.76 | 4 | 56394 | 10 | 56235659 |
Localised oedema | 18.58 | 11.76 | 24 | 56374 | 4985 | 56230684 |
Multiple sclerosis relapse | 18.50 | 11.76 | 11 | 56387 | 44892 | 56190777 |
Meningomyelocele | 18.49 | 11.76 | 10 | 56388 | 605 | 56235064 |
Umbilical cord abnormality | 18.47 | 11.76 | 10 | 56388 | 606 | 56235063 |
Sepsis neonatal | 18.42 | 11.76 | 9 | 56389 | 440 | 56235229 |
Pulmonary alveolar haemorrhage | 18.33 | 11.76 | 22 | 56376 | 4242 | 56231427 |
Uterine hypotonus | 18.04 | 11.76 | 6 | 56392 | 105 | 56235564 |
C-reactive protein increased | 18.00 | 11.76 | 32 | 56366 | 78652 | 56157017 |
Hyperandrogenism | 17.94 | 11.76 | 6 | 56392 | 107 | 56235562 |
Malignant neoplasm progression | 17.69 | 11.76 | 29 | 56369 | 73558 | 56162111 |
Hepatic function abnormal | 17.61 | 11.76 | 75 | 56323 | 34483 | 56201186 |
Infusion site infection | 17.55 | 11.76 | 14 | 56384 | 1638 | 56234031 |
Tachypnoea | 17.49 | 11.76 | 44 | 56354 | 15386 | 56220283 |
Product dose omission issue | 17.38 | 11.76 | 295 | 56103 | 204458 | 56031211 |
Mediastinal effusion | 17.33 | 11.76 | 5 | 56393 | 53 | 56235616 |
Supraventricular tachycardia | 17.32 | 11.76 | 40 | 56358 | 13251 | 56222418 |
Gout | 17.29 | 11.76 | 38 | 56360 | 12183 | 56223486 |
Sepsis | 17.23 | 11.76 | 215 | 56183 | 139625 | 56096044 |
Cardioversion | 17.17 | 11.76 | 12 | 56386 | 1149 | 56234520 |
Osteonecrosis of jaw | 17.12 | 11.76 | 6 | 56392 | 33352 | 56202317 |
Bronchospasm | 17.05 | 11.76 | 44 | 56354 | 15625 | 56220044 |
Paraesthesia | 17.05 | 11.76 | 70 | 56328 | 130444 | 56105225 |
Right ventricular systolic pressure increased | 17.04 | 11.76 | 9 | 56389 | 519 | 56235150 |
Upper respiratory tract infection | 16.98 | 11.76 | 126 | 56272 | 71162 | 56164507 |
Injury | 16.94 | 11.76 | 21 | 56377 | 59830 | 56175839 |
Oxygen consumption decreased | 16.92 | 11.76 | 7 | 56391 | 230 | 56235439 |
Coma | 16.82 | 11.76 | 21 | 56377 | 59634 | 56176035 |
Exomphalos | 16.64 | 11.76 | 9 | 56389 | 544 | 56235125 |
Ventilation perfusion mismatch | 16.56 | 11.76 | 7 | 56391 | 243 | 56235426 |
Abdominal cavity drainage | 16.47 | 11.76 | 8 | 56390 | 386 | 56235283 |
Argon plasma coagulation | 16.32 | 11.76 | 4 | 56394 | 21 | 56235648 |
Feeling abnormal | 16.28 | 11.76 | 205 | 56193 | 133397 | 56102272 |
Terminal state | 16.25 | 11.76 | 15 | 56383 | 2138 | 56233531 |
Platelet transfusion | 16.23 | 11.76 | 10 | 56388 | 774 | 56234895 |
Oedematous kidney | 16.20 | 11.76 | 5 | 56393 | 68 | 56235601 |
Hospice care | 16.09 | 11.76 | 25 | 56373 | 6155 | 56229514 |
Enlarged clitoris | 16.04 | 11.76 | 6 | 56392 | 150 | 56235519 |
Pulmonary pain | 16.04 | 11.76 | 17 | 56381 | 2863 | 56232806 |
Pulmonary artery dilatation | 15.92 | 11.76 | 7 | 56391 | 268 | 56235401 |
Wheezing | 15.87 | 11.76 | 129 | 56269 | 74897 | 56160772 |
Fibromyalgia | 15.76 | 11.76 | 22 | 56376 | 59581 | 56176088 |
Pulmonary haemorrhage | 15.69 | 11.76 | 26 | 56372 | 6757 | 56228912 |
Cold burn | 15.64 | 11.76 | 3 | 56395 | 3 | 56235666 |
Acute postoperative sialadenitis | 15.59 | 11.76 | 4 | 56394 | 26 | 56235643 |
Echocardiogram | 15.46 | 11.76 | 4 | 56394 | 27 | 56235642 |
Accident | 15.45 | 11.76 | 23 | 56375 | 5453 | 56230216 |
Jugular vein distension | 15.25 | 11.76 | 10 | 56388 | 862 | 56234807 |
Tracheostomy | 15.15 | 11.76 | 9 | 56389 | 652 | 56235017 |
Pulmonary capillary haemangiomatosis | 15.10 | 11.76 | 4 | 56394 | 30 | 56235639 |
Rehabilitation therapy | 15.09 | 11.76 | 12 | 56386 | 1398 | 56234271 |
Breath sounds abnormal | 15.07 | 11.76 | 30 | 56368 | 8977 | 56226692 |
PO2 decreased | 15.06 | 11.76 | 12 | 56386 | 1401 | 56234268 |
Lung assist device therapy | 15.01 | 11.76 | 5 | 56393 | 88 | 56235581 |
Pneumonia bacterial | 14.97 | 11.76 | 28 | 56370 | 8000 | 56227669 |
Procedural hypotension | 14.94 | 11.76 | 11 | 56387 | 1143 | 56234526 |
Neuropathy peripheral | 14.85 | 11.76 | 53 | 56345 | 102840 | 56132829 |
Rhonchi | 14.85 | 11.76 | 15 | 56383 | 2389 | 56233280 |
Blood urea increased | 14.78 | 11.76 | 56 | 56342 | 24417 | 56211252 |
Idiopathic pulmonary fibrosis | 14.68 | 11.76 | 12 | 56386 | 1454 | 56234215 |
Bone marrow failure | 14.67 | 11.76 | 5 | 56393 | 28281 | 56207388 |
Red blood cell count decreased | 14.62 | 11.76 | 74 | 56324 | 36543 | 56199126 |
Systemic scleroderma | 14.53 | 11.76 | 10 | 56388 | 934 | 56234735 |
Paradoxical embolism | 14.45 | 11.76 | 4 | 56394 | 36 | 56235633 |
Tachycardia | 14.45 | 11.76 | 166 | 56232 | 105710 | 56129959 |
Neoplasm progression | 14.43 | 11.76 | 7 | 56391 | 32009 | 56203660 |
Carbon dioxide increased | 14.42 | 11.76 | 11 | 56387 | 1206 | 56234463 |
Hypoglycaemia | 14.36 | 11.76 | 21 | 56377 | 55794 | 56179875 |
Decreased appetite | 14.19 | 11.76 | 303 | 56095 | 218928 | 56016741 |
Bursitis | 14.09 | 11.76 | 5 | 56393 | 27577 | 56208092 |
Secretion discharge | 14.03 | 11.76 | 32 | 56366 | 10514 | 56225155 |
Catheter site warmth | 14.02 | 11.76 | 6 | 56392 | 215 | 56235454 |
COVID-19 pneumonia | 14.02 | 11.76 | 33 | 56365 | 11069 | 56224600 |
Therapy change | 14.01 | 11.76 | 22 | 56376 | 5466 | 56230203 |
Catheter site inflammation | 13.98 | 11.76 | 9 | 56389 | 752 | 56234917 |
Catheter site hypersensitivity | 13.88 | 11.76 | 5 | 56393 | 112 | 56235557 |
Hip arthroplasty | 13.87 | 11.76 | 11 | 56387 | 38612 | 56197057 |
Middle ear effusion | 13.87 | 11.76 | 14 | 56384 | 2228 | 56233441 |
Weight decreased | 13.79 | 11.76 | 327 | 56071 | 240387 | 55995282 |
Injection site bruising | 13.79 | 11.76 | 11 | 56387 | 38510 | 56197159 |
Blood pressure increased | 13.77 | 11.76 | 87 | 56311 | 145089 | 56090580 |
Pregnancy | 13.74 | 11.76 | 8 | 56390 | 33025 | 56202644 |
Type 2 diabetes mellitus | 13.74 | 11.76 | 16 | 56382 | 46846 | 56188823 |
Dizziness exertional | 13.73 | 11.76 | 7 | 56391 | 375 | 56235294 |
Increased bronchial secretion | 13.72 | 11.76 | 12 | 56386 | 1595 | 56234074 |
Catheter site haemorrhage | 13.68 | 11.76 | 16 | 56382 | 3002 | 56232667 |
Gastrointestinal arteriovenous malformation | 13.68 | 11.76 | 8 | 56390 | 563 | 56235106 |
Biopsy liver | 13.52 | 11.76 | 7 | 56391 | 387 | 56235282 |
Pneumomediastinum | 13.52 | 11.76 | 11 | 56387 | 1324 | 56234345 |
Spina bifida | 13.49 | 11.76 | 9 | 56389 | 799 | 56234870 |
Angioedema | 13.44 | 11.76 | 13 | 56385 | 41440 | 56194229 |
Therapeutic response decreased | 13.43 | 11.76 | 20 | 56378 | 52738 | 56182931 |
Mucosal inflammation | 13.22 | 11.76 | 14 | 56384 | 42796 | 56192873 |
Colitis ulcerative | 13.20 | 11.76 | 4 | 56394 | 24387 | 56211282 |
Apnoea | 13.19 | 11.76 | 25 | 56373 | 7217 | 56228452 |
Rhabdomyolysis | 12.89 | 11.76 | 13 | 56385 | 40645 | 56195024 |
Right ventricular dilatation | 12.87 | 11.76 | 10 | 56388 | 1126 | 56234543 |
Urinary retention | 12.86 | 11.76 | 6 | 56392 | 28068 | 56207601 |
Hepatitis | 12.84 | 11.76 | 10 | 56388 | 35431 | 56200238 |
Hypertension | 12.84 | 11.76 | 170 | 56228 | 244108 | 55991561 |
Choking | 12.75 | 11.76 | 28 | 56370 | 8969 | 56226700 |
Therapy non-responder | 12.71 | 11.76 | 105 | 56293 | 61250 | 56174419 |
Administration site pruritus | 12.62 | 11.76 | 6 | 56392 | 276 | 56235393 |
Nasal discomfort | 12.60 | 11.76 | 18 | 56380 | 4114 | 56231555 |
Neutrophil count decreased | 12.57 | 11.76 | 19 | 56379 | 49803 | 56185866 |
Right ventricular hypertrophy | 12.56 | 11.76 | 8 | 56390 | 656 | 56235013 |
Inflammation | 12.53 | 11.76 | 32 | 56366 | 69039 | 56166630 |
Hypozincaemia | 12.53 | 11.76 | 3 | 56395 | 14 | 56235655 |
Choking sensation | 12.49 | 11.76 | 16 | 56382 | 3295 | 56232374 |
Vascular cauterisation | 12.48 | 11.76 | 4 | 56394 | 62 | 56235607 |
Emergency care | 12.47 | 11.76 | 9 | 56389 | 907 | 56234762 |
Polypectomy | 12.45 | 11.76 | 8 | 56390 | 666 | 56235003 |
Dialysis | 12.42 | 11.76 | 29 | 56369 | 9673 | 56225996 |
Cardiac failure high output | 12.40 | 11.76 | 6 | 56392 | 287 | 56235382 |
Menstrual discomfort | 12.36 | 11.76 | 3 | 56395 | 15 | 56235654 |
Lung squamous cell carcinoma stage I | 12.36 | 11.76 | 3 | 56395 | 15 | 56235654 |
Decreased activity | 12.34 | 11.76 | 21 | 56377 | 5575 | 56230094 |
Catheter site erosion | 12.30 | 11.76 | 4 | 56394 | 65 | 56235604 |
Glossoptosis | 12.25 | 11.76 | 4 | 56394 | 66 | 56235603 |
Acute right ventricular failure | 12.18 | 11.76 | 5 | 56393 | 161 | 56235508 |
Oesophageal dilation procedure | 12.08 | 11.76 | 4 | 56394 | 69 | 56235600 |
Brain hypoxia | 12.07 | 11.76 | 7 | 56391 | 485 | 56235184 |
Rash maculo-papular | 12.03 | 11.76 | 7 | 56391 | 28900 | 56206769 |
Chills | 11.89 | 11.76 | 156 | 56242 | 102448 | 56133221 |
Abdominal pain | 11.89 | 11.76 | 185 | 56213 | 258620 | 55977049 |
Stress cardiomyopathy | 11.88 | 11.76 | 26 | 56372 | 8310 | 56227359 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Dyspnoea | 383.33 | 12.70 | 890 | 26836 | 342589 | 31327029 |
Oxygen saturation decreased | 331.12 | 12.70 | 302 | 27424 | 48813 | 31620805 |
Pulmonary arterial hypertension | 273.71 | 12.70 | 145 | 27581 | 9676 | 31659942 |
Hypoxia | 225.56 | 12.70 | 248 | 27478 | 50065 | 31619553 |
Right ventricular failure | 204.88 | 12.70 | 113 | 27613 | 8169 | 31661449 |
Chronic obstructive pulmonary disease | 187.61 | 12.70 | 214 | 27512 | 44952 | 31624666 |
Oxygen consumption increased | 171.16 | 12.70 | 58 | 27668 | 1244 | 31668374 |
Pulmonary hypertension | 170.77 | 12.70 | 141 | 27585 | 19900 | 31649718 |
Respiratory failure | 138.15 | 12.70 | 286 | 27440 | 101163 | 31568455 |
Fluid retention | 117.55 | 12.70 | 126 | 27600 | 24676 | 31644942 |
Concomitant disease aggravated | 114.87 | 12.70 | 66 | 27660 | 5158 | 31664460 |
Pneumonia | 106.83 | 12.70 | 575 | 27151 | 334737 | 31334881 |
Acute respiratory failure | 99.98 | 12.70 | 123 | 27603 | 27932 | 31641686 |
Dyspnoea exertional | 82.67 | 12.70 | 133 | 27593 | 38704 | 31630914 |
Oxygen therapy | 68.08 | 12.70 | 26 | 27700 | 794 | 31668824 |
Transfusion | 65.55 | 12.70 | 54 | 27672 | 7586 | 31662032 |
Toxicity to various agents | 63.87 | 12.70 | 40 | 27686 | 181447 | 31488171 |
Pain in jaw | 62.92 | 12.70 | 65 | 27661 | 12190 | 31657428 |
Thermal burn | 61.52 | 12.70 | 34 | 27692 | 2464 | 31667154 |
Hypervolaemia | 60.19 | 12.70 | 77 | 27649 | 18174 | 31651444 |
Nasal congestion | 56.50 | 12.70 | 79 | 27647 | 20302 | 31649316 |
Completed suicide | 56.09 | 12.70 | 7 | 27719 | 91507 | 31578111 |
Respiratory distress | 53.26 | 12.70 | 101 | 27625 | 33452 | 31636166 |
Cerebral artery thrombosis | 52.10 | 12.70 | 21 | 27705 | 742 | 31668876 |
Drug abuse | 50.76 | 12.70 | 8 | 27718 | 87750 | 31581868 |
Brain scan abnormal | 49.72 | 12.70 | 21 | 27705 | 837 | 31668781 |
Pulmonary oedema | 48.61 | 12.70 | 115 | 27611 | 44387 | 31625231 |
Idiopathic pulmonary fibrosis | 48.11 | 12.70 | 35 | 27691 | 4095 | 31665523 |
Cough | 48.03 | 12.70 | 239 | 27487 | 134575 | 31535043 |
Pulmonary arterial pressure increased | 45.61 | 12.70 | 22 | 27704 | 1200 | 31668418 |
Brain natriuretic peptide increased | 38.80 | 12.70 | 33 | 27693 | 4843 | 31664775 |
Hypercapnia | 38.17 | 12.70 | 30 | 27696 | 3941 | 31665677 |
Condition aggravated | 35.36 | 12.70 | 255 | 27471 | 163754 | 31505864 |
Oedema | 35.12 | 12.70 | 99 | 27627 | 42462 | 31627156 |
Neutropenia | 34.78 | 12.70 | 43 | 27683 | 140321 | 31529297 |
Pneumothorax | 34.72 | 12.70 | 57 | 27669 | 16853 | 31652765 |
Lung transplant | 34.24 | 12.70 | 21 | 27705 | 1849 | 31667769 |
Blood pressure decreased | 34.11 | 12.70 | 106 | 27620 | 47985 | 31621633 |
Haemoptysis | 33.86 | 12.70 | 82 | 27644 | 32107 | 31637511 |
Catheter site erythema | 33.49 | 12.70 | 18 | 27708 | 1234 | 31668384 |
Areflexia | 33.11 | 12.70 | 24 | 27702 | 2792 | 31666826 |
Catheter management | 30.47 | 12.70 | 15 | 27711 | 856 | 31668762 |
Cor pulmonale | 30.18 | 12.70 | 14 | 27712 | 699 | 31668919 |
Drug ineffective | 29.99 | 12.70 | 213 | 27513 | 395360 | 31274258 |
Cardiac arrest | 28.96 | 12.70 | 154 | 27572 | 88908 | 31580710 |
Rheumatoid arthritis | 28.46 | 12.70 | 4 | 27722 | 47805 | 31621813 |
Emphysema | 28.41 | 12.70 | 37 | 27689 | 8881 | 31660737 |
Cardiac failure | 28.20 | 12.70 | 149 | 27577 | 85804 | 31583814 |
Oedema peripheral | 27.34 | 12.70 | 177 | 27549 | 109662 | 31559956 |
Chronic respiratory failure | 27.22 | 12.70 | 16 | 27710 | 1304 | 31668314 |
Lung disorder | 26.50 | 12.70 | 75 | 27651 | 32237 | 31637381 |
Pulmonary function test abnormal | 26.28 | 12.70 | 19 | 27707 | 2202 | 31667416 |
Neuromuscular block prolonged | 25.73 | 12.70 | 11 | 27715 | 452 | 31669166 |
Cyanosis | 24.69 | 12.70 | 40 | 27686 | 11695 | 31657923 |
Mechanical ventilation | 24.37 | 12.70 | 17 | 27709 | 1862 | 31667756 |
Catheter removal | 23.08 | 12.70 | 8 | 27718 | 184 | 31669434 |
Catheterisation cardiac | 22.94 | 12.70 | 18 | 27708 | 2358 | 31667260 |
Catheter site haemorrhage | 22.78 | 12.70 | 17 | 27709 | 2067 | 31667551 |
Accident | 22.37 | 12.70 | 22 | 27704 | 3889 | 31665729 |
Pulmonary veno-occlusive disease | 22.23 | 12.70 | 10 | 27716 | 465 | 31669153 |
Transplant evaluation | 21.77 | 12.70 | 10 | 27716 | 488 | 31669130 |
Air embolism | 21.40 | 12.70 | 7 | 27719 | 134 | 31669484 |
Intentional overdose | 21.32 | 12.70 | 5 | 27721 | 41384 | 31628234 |
Catheter placement | 21.27 | 12.70 | 11 | 27715 | 697 | 31668921 |
Subacute combined cord degeneration | 20.97 | 12.70 | 7 | 27719 | 143 | 31669475 |
Rotavirus infection | 20.60 | 12.70 | 9 | 27717 | 390 | 31669228 |
Hypotension | 20.56 | 12.70 | 271 | 27455 | 204347 | 31465271 |
Catheter site pain | 20.48 | 12.70 | 13 | 27713 | 1216 | 31668402 |
Pulmonary function test decreased | 20.27 | 12.70 | 22 | 27704 | 4363 | 31665255 |
Carbon dioxide increased | 20.09 | 12.70 | 12 | 27714 | 1007 | 31668611 |
Headache | 20.04 | 12.70 | 247 | 27479 | 183405 | 31486213 |
Catheter site discharge | 19.95 | 12.70 | 10 | 27716 | 593 | 31669025 |
Anaesthetic complication | 19.93 | 12.70 | 12 | 27714 | 1022 | 31668596 |
Catheter site granuloma | 19.72 | 12.70 | 5 | 27721 | 36 | 31669582 |
Pulmonary fibrosis | 19.21 | 12.70 | 44 | 27682 | 16616 | 31653002 |
Interstitial lung disease | 19.15 | 12.70 | 105 | 27621 | 61298 | 31608320 |
Hyperthermia malignant | 19.09 | 12.70 | 15 | 27711 | 1969 | 31667649 |
Catheter site pruritus | 19.06 | 12.70 | 8 | 27718 | 314 | 31669304 |
Bradycardia | 18.65 | 12.70 | 114 | 27612 | 69213 | 31600405 |
Burns third degree | 18.57 | 12.70 | 7 | 27719 | 206 | 31669412 |
Productive cough | 18.53 | 12.70 | 68 | 27658 | 33472 | 31636146 |
Aggression | 18.26 | 12.70 | 5 | 27721 | 37286 | 31632332 |
Suicide attempt | 18.22 | 12.70 | 5 | 27721 | 37243 | 31632375 |
Burns second degree | 18.11 | 12.70 | 8 | 27718 | 356 | 31669262 |
Catheter site warmth | 18.00 | 12.70 | 5 | 27721 | 53 | 31669565 |
Hyponatraemia | 17.85 | 12.70 | 23 | 27703 | 73776 | 31595842 |
Respiratory acidosis | 17.50 | 12.70 | 21 | 27705 | 4641 | 31664977 |
Treatment failure | 17.30 | 12.70 | 7 | 27719 | 40785 | 31628833 |
Cardiac failure congestive | 16.81 | 12.70 | 123 | 27603 | 79264 | 31590354 |
Ventricular tachycardia | 16.57 | 12.70 | 52 | 27674 | 23649 | 31645969 |
Hypocapnia | 16.37 | 12.70 | 6 | 27720 | 163 | 31669455 |
Ventilation perfusion mismatch | 16.23 | 12.70 | 5 | 27721 | 78 | 31669540 |
Pulmonary hypertensive crisis | 16.23 | 12.70 | 6 | 27720 | 167 | 31669451 |
Therapeutic product effect incomplete | 16.22 | 12.70 | 9 | 27717 | 43687 | 31625931 |
Epistaxis | 16.18 | 12.70 | 91 | 27635 | 53616 | 31616002 |
Walking distance test abnormal | 16.17 | 12.70 | 6 | 27720 | 169 | 31669449 |
Infusion site vesicles | 16.13 | 12.70 | 6 | 27720 | 170 | 31669448 |
Accidental underdose | 16.06 | 12.70 | 8 | 27718 | 468 | 31669150 |
Pulse pressure decreased | 15.84 | 12.70 | 6 | 27720 | 179 | 31669439 |
Anaesthetic complication cardiac | 15.76 | 12.70 | 4 | 27722 | 29 | 31669589 |
Thoracic cavity drainage | 15.69 | 12.70 | 6 | 27720 | 184 | 31669434 |
Respiratory tract infection | 15.62 | 12.70 | 42 | 27684 | 17519 | 31652099 |
Confusional state | 15.51 | 12.70 | 62 | 27664 | 133272 | 31536346 |
Psoriasis | 15.45 | 12.70 | 11 | 27715 | 46708 | 31622910 |
PaO2/FiO2 ratio decreased | 15.30 | 12.70 | 4 | 27722 | 33 | 31669585 |
Tachypnoea | 15.25 | 12.70 | 40 | 27686 | 16443 | 31653175 |
Acute kidney injury | 15.18 | 12.70 | 164 | 27562 | 279550 | 31390068 |
Barotrauma | 15.09 | 12.70 | 4 | 27722 | 35 | 31669583 |
Pulmonary capillary haemangiomatosis | 15.09 | 12.70 | 4 | 27722 | 35 | 31669583 |
Dependence on oxygen therapy | 15.05 | 12.70 | 6 | 27720 | 206 | 31669412 |
Catheter site inflammation | 14.99 | 12.70 | 6 | 27720 | 208 | 31669410 |
Complication associated with device | 14.97 | 12.70 | 21 | 27705 | 5408 | 31664210 |
White blood cell count decreased | 14.93 | 12.70 | 34 | 27692 | 87364 | 31582254 |
Pulmonary congestion | 14.65 | 12.70 | 34 | 27692 | 12949 | 31656669 |
Abdominal pain | 14.48 | 12.70 | 72 | 27654 | 145880 | 31523738 |
Drug interaction | 14.44 | 12.70 | 115 | 27611 | 208428 | 31461190 |
Acute right ventricular failure | 14.26 | 12.70 | 5 | 27721 | 119 | 31669499 |
Hemiplegia | 14.26 | 12.70 | 23 | 27703 | 6699 | 31662919 |
Pulseless electrical activity | 14.24 | 12.70 | 23 | 27703 | 6704 | 31662914 |
Pulmonary alveolar haemorrhage | 14.15 | 12.70 | 23 | 27703 | 6743 | 31662875 |
Apnoea | 14.02 | 12.70 | 22 | 27704 | 6260 | 31663358 |
Pneumomediastinum | 13.98 | 12.70 | 13 | 27713 | 2144 | 31667474 |
Thrombocytopenia | 13.83 | 12.70 | 71 | 27655 | 142676 | 31526942 |
Syncope | 13.71 | 12.70 | 124 | 27602 | 85058 | 31584560 |
Dyspnoea at rest | 13.41 | 12.70 | 16 | 27710 | 3515 | 31666103 |
Aspartate aminotransferase increased | 13.17 | 12.70 | 97 | 27629 | 62622 | 31606996 |
Leukopenia | 13.00 | 12.70 | 19 | 27707 | 57809 | 31611809 |
Procedural complication | 12.95 | 12.70 | 17 | 27709 | 4112 | 31665506 |
Rectal haemorrhage | 12.74 | 12.70 | 8 | 27718 | 36296 | 31633322 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Dyspnoea | 1064.81 | 11.38 | 2398 | 70719 | 767662 | 70087665 |
Pulmonary arterial hypertension | 870.64 | 11.38 | 496 | 72621 | 32359 | 70822968 |
Oxygen saturation decreased | 784.14 | 11.38 | 770 | 72347 | 115659 | 70739668 |
Pulmonary hypertension | 599.74 | 11.38 | 447 | 72670 | 46089 | 70809238 |
Oxygen consumption increased | 572.46 | 11.38 | 206 | 72911 | 4474 | 70850853 |
Right ventricular failure | 554.54 | 11.38 | 323 | 72794 | 21951 | 70833376 |
Fluid retention | 480.82 | 11.38 | 448 | 72669 | 62937 | 70792390 |
Hypoxia | 456.47 | 11.38 | 521 | 72596 | 92823 | 70762504 |
Dyspnoea exertional | 409.45 | 11.38 | 453 | 72664 | 77977 | 70777350 |
Chronic obstructive pulmonary disease | 363.76 | 11.38 | 424 | 72693 | 77217 | 70778110 |
Respiratory failure | 281.56 | 11.38 | 570 | 72547 | 168165 | 70687162 |
Hypervolaemia | 256.41 | 11.38 | 257 | 72860 | 39449 | 70815878 |
Transfusion | 249.38 | 11.38 | 184 | 72933 | 18652 | 70836675 |
Pain in jaw | 239.19 | 11.38 | 256 | 72861 | 42413 | 70812914 |
Drug ineffective | 236.47 | 11.38 | 379 | 72738 | 939373 | 69915954 |
Oxygen therapy | 219.56 | 11.38 | 86 | 73031 | 2376 | 70852951 |
Pneumonia | 214.48 | 11.38 | 1192 | 71925 | 595040 | 70260287 |
Acute respiratory failure | 207.34 | 11.38 | 266 | 72851 | 53399 | 70801928 |
Rheumatoid arthritis | 204.48 | 11.38 | 29 | 73088 | 291776 | 70563551 |
Completed suicide | 202.93 | 11.38 | 7 | 73110 | 227128 | 70628199 |
Toxicity to various agents | 198.61 | 11.38 | 73 | 73044 | 382099 | 70473228 |
Nasal congestion | 195.58 | 11.38 | 287 | 72830 | 65385 | 70789942 |
Concomitant disease aggravated | 189.49 | 11.38 | 131 | 72986 | 11983 | 70843344 |
Oedema peripheral | 164.45 | 11.38 | 563 | 72554 | 227528 | 70627799 |
Pulmonary oedema | 141.88 | 11.38 | 282 | 72835 | 81996 | 70773331 |
Cough | 138.23 | 11.38 | 682 | 72435 | 324695 | 70530632 |
Oedema | 135.03 | 11.38 | 317 | 72800 | 103264 | 70752063 |
Pulmonary arterial pressure increased | 130.26 | 11.38 | 71 | 73046 | 4238 | 70851089 |
Catheter site erythema | 123.74 | 11.38 | 72 | 73045 | 4876 | 70850451 |
Drug abuse | 117.51 | 11.38 | 9 | 73108 | 147247 | 70708080 |
Cardiac failure | 112.85 | 11.38 | 365 | 72752 | 143176 | 70712151 |
Contraindicated product administered | 110.98 | 11.38 | 7 | 73110 | 134605 | 70720722 |
Brain natriuretic peptide increased | 108.54 | 11.38 | 80 | 73037 | 8091 | 70847236 |
Therapeutic product effect decreased | 108.01 | 11.38 | 11 | 73106 | 143007 | 70712320 |
Catheter site pruritus | 107.58 | 11.38 | 50 | 73067 | 2121 | 70853206 |
Treatment failure | 101.64 | 11.38 | 14 | 73103 | 144128 | 70711199 |
Lung transplant | 100.90 | 11.38 | 60 | 73057 | 4230 | 70851097 |
Chest pain | 99.80 | 11.38 | 517 | 72600 | 250743 | 70604584 |
Headache | 98.44 | 11.38 | 971 | 72146 | 579434 | 70275893 |
Neutropenia | 98.20 | 11.38 | 73 | 73044 | 257083 | 70598244 |
Productive cough | 98.01 | 11.38 | 236 | 72881 | 78101 | 70777226 |
Blood pressure decreased | 95.08 | 11.38 | 257 | 72860 | 91258 | 70764069 |
Haemoptysis | 93.10 | 11.38 | 180 | 72937 | 51272 | 70804055 |
Arthropathy | 91.88 | 11.38 | 21 | 73096 | 150036 | 70705291 |
Hypercapnia | 91.86 | 11.38 | 73 | 73044 | 8256 | 70847071 |
Catheter management | 88.26 | 11.38 | 51 | 73066 | 3408 | 70851919 |
Drug intolerance | 86.24 | 11.38 | 64 | 73053 | 225623 | 70629704 |
Catheterisation cardiac | 84.87 | 11.38 | 58 | 73059 | 5205 | 70850122 |
Alopecia | 82.92 | 11.38 | 51 | 73066 | 198439 | 70656888 |
Drug hypersensitivity | 81.72 | 11.38 | 90 | 73027 | 262369 | 70592958 |
Epistaxis | 80.65 | 11.38 | 261 | 72856 | 102366 | 70752961 |
Respiratory distress | 76.41 | 11.38 | 172 | 72945 | 54478 | 70800849 |
Syncope | 75.00 | 11.38 | 354 | 72763 | 165355 | 70689972 |
Cyanosis | 72.80 | 11.38 | 104 | 73013 | 23102 | 70832225 |
Rash | 71.30 | 11.38 | 278 | 72839 | 510284 | 70345043 |
Scleroderma | 71.05 | 11.38 | 51 | 73066 | 4950 | 70850377 |
Joint swelling | 70.19 | 11.38 | 95 | 73022 | 253116 | 70602211 |
Hand deformity | 69.80 | 11.38 | 5 | 73112 | 86477 | 70768850 |
Catheter site pain | 69.07 | 11.38 | 50 | 73067 | 4918 | 70850409 |
Pulmonary veno-occlusive disease | 68.81 | 11.38 | 33 | 73084 | 1503 | 70853824 |
Thermal burn | 67.60 | 11.38 | 55 | 73062 | 6431 | 70848896 |
Dependence on oxygen therapy | 67.05 | 11.38 | 23 | 73094 | 431 | 70854896 |
Intentional overdose | 66.09 | 11.38 | 11 | 73106 | 98424 | 70756903 |
Glossodynia | 64.39 | 11.38 | 7 | 73110 | 86480 | 70768847 |
Hypotension | 62.39 | 11.38 | 664 | 72453 | 403717 | 70451610 |
Unevaluable event | 62.07 | 11.38 | 154 | 72963 | 51909 | 70803418 |
Catheter site discharge | 61.93 | 11.38 | 35 | 73082 | 2242 | 70853085 |
Device alarm issue | 61.68 | 11.38 | 33 | 73084 | 1897 | 70853430 |
Stomatitis | 61.03 | 11.38 | 28 | 73089 | 128483 | 70726844 |
Condition aggravated | 59.95 | 11.38 | 689 | 72428 | 426946 | 70428381 |
Pericarditis | 57.91 | 11.38 | 9 | 73108 | 84696 | 70770631 |
Musculoskeletal stiffness | 57.60 | 11.38 | 41 | 73076 | 147719 | 70707608 |
Chronic respiratory failure | 56.02 | 11.38 | 35 | 73082 | 2697 | 70852630 |
Flushing | 54.91 | 11.38 | 198 | 72919 | 81974 | 70773353 |
Pleural effusion | 54.49 | 11.38 | 276 | 72841 | 132588 | 70722739 |
Catheter site infection | 54.11 | 11.38 | 47 | 73070 | 6013 | 70849314 |
Cardiac failure congestive | 53.89 | 11.38 | 279 | 72838 | 135178 | 70720149 |
Pericardial effusion | 53.46 | 11.38 | 127 | 72990 | 41649 | 70813678 |
Palpitations | 53.33 | 11.38 | 241 | 72876 | 110512 | 70744815 |
Pulmonary hypertensive crisis | 52.74 | 11.38 | 18 | 73099 | 332 | 70854995 |
Device related infection | 52.68 | 11.38 | 108 | 73009 | 32077 | 70823250 |
Overdose | 51.93 | 11.38 | 59 | 73058 | 169686 | 70685641 |
Off label use | 51.07 | 11.38 | 505 | 72612 | 742555 | 70112772 |
Suicide attempt | 50.96 | 11.38 | 10 | 73107 | 79500 | 70775827 |
Hepatic enzyme increased | 50.88 | 11.38 | 52 | 73065 | 156938 | 70698389 |
Dizziness | 50.66 | 11.38 | 714 | 72403 | 463427 | 70391900 |
Arthralgia | 50.56 | 11.38 | 308 | 72809 | 503082 | 70352245 |
Transplant evaluation | 50.39 | 11.38 | 27 | 73090 | 1557 | 70853770 |
Therapeutic product effect incomplete | 49.77 | 11.38 | 31 | 73086 | 119851 | 70735476 |
Air embolism | 49.16 | 11.38 | 18 | 73099 | 411 | 70854916 |
Catheter placement | 48.80 | 11.38 | 32 | 73085 | 2681 | 70852646 |
Systemic lupus erythematosus | 48.70 | 11.38 | 22 | 73095 | 101880 | 70753447 |
Emphysema | 47.99 | 11.38 | 68 | 73049 | 14992 | 70840335 |
Hypersensitivity | 47.41 | 11.38 | 104 | 73013 | 229708 | 70625619 |
Infusion related reaction | 47.15 | 11.38 | 82 | 73035 | 197452 | 70657875 |
Catheter site rash | 46.56 | 11.38 | 22 | 73095 | 969 | 70854358 |
Psoriasis | 45.88 | 11.38 | 22 | 73095 | 98411 | 70756916 |
Cor pulmonale | 45.81 | 11.38 | 28 | 73089 | 2075 | 70853252 |
Injection site pain | 42.81 | 11.38 | 35 | 73082 | 117584 | 70737743 |
Dyspnoea at rest | 41.92 | 11.38 | 43 | 73074 | 6776 | 70848551 |
Lung disorder | 41.08 | 11.38 | 161 | 72956 | 69323 | 70786004 |
Pulmonary function test decreased | 40.21 | 11.38 | 42 | 73075 | 6759 | 70848568 |
Febrile neutropenia | 40.08 | 11.38 | 95 | 73022 | 204223 | 70651104 |
Idiopathic pulmonary fibrosis | 40.07 | 11.38 | 36 | 73081 | 4815 | 70850512 |
Anaesthetic complication | 40.03 | 11.38 | 28 | 73089 | 2608 | 70852719 |
Brain scan abnormal | 40.01 | 11.38 | 21 | 73096 | 1161 | 70854166 |
Infusion site pain | 39.51 | 11.38 | 54 | 73063 | 11510 | 70843817 |
Nasal dryness | 39.26 | 11.38 | 32 | 73085 | 3751 | 70851576 |
Confusional state | 38.88 | 11.38 | 156 | 72961 | 284242 | 70571085 |
Cerebral artery thrombosis | 38.74 | 11.38 | 20 | 73097 | 1068 | 70854259 |
Orthopnoea | 38.47 | 11.38 | 48 | 73069 | 9360 | 70845967 |
Pulmonary congestion | 38.36 | 11.38 | 82 | 73035 | 25072 | 70830255 |
Cardiac arrest | 38.26 | 11.38 | 289 | 72828 | 159545 | 70695782 |
Pain | 37.65 | 11.38 | 441 | 72676 | 628375 | 70226952 |
Walking distance test abnormal | 36.78 | 11.38 | 17 | 73100 | 712 | 70854615 |
Hospitalisation | 36.31 | 11.38 | 175 | 72942 | 82393 | 70772934 |
Malaise | 35.83 | 11.38 | 636 | 72481 | 432296 | 70423031 |
Helicobacter infection | 35.67 | 11.38 | 7 | 73110 | 55649 | 70799678 |
Intentional product use issue | 35.41 | 11.38 | 43 | 73074 | 120099 | 70735228 |
Discomfort | 35.22 | 11.38 | 34 | 73083 | 105402 | 70749925 |
Exercise tolerance decreased | 35.21 | 11.38 | 43 | 73074 | 8205 | 70847122 |
Cardiac failure acute | 35.13 | 11.38 | 64 | 73053 | 17423 | 70837904 |
Pneumothorax | 34.62 | 11.38 | 80 | 73037 | 25766 | 70829561 |
Injection site erythema | 34.44 | 11.38 | 16 | 73101 | 72908 | 70782419 |
Device occlusion | 33.99 | 11.38 | 48 | 73069 | 10547 | 70844780 |
Coma | 33.83 | 11.38 | 27 | 73090 | 91817 | 70763510 |
Mobility decreased | 33.50 | 11.38 | 34 | 73083 | 102965 | 70752362 |
Urticaria | 33.43 | 11.38 | 74 | 73043 | 162975 | 70692352 |
Suicidal ideation | 33.29 | 11.38 | 15 | 73102 | 69581 | 70785746 |
Left ventricular failure | 33.27 | 11.38 | 43 | 73074 | 8685 | 70846642 |
Hypoglycaemia | 33.21 | 11.38 | 29 | 73088 | 94335 | 70760992 |
Pruritus | 32.80 | 11.38 | 215 | 72902 | 345345 | 70509982 |
Oxygen saturation abnormal | 32.62 | 11.38 | 29 | 73088 | 3825 | 70851502 |
Leukopenia | 32.62 | 11.38 | 37 | 73080 | 106523 | 70748804 |
Injection site reaction | 32.52 | 11.38 | 6 | 73111 | 49846 | 70805481 |
Catheter site haemorrhage | 32.51 | 11.38 | 32 | 73085 | 4799 | 70850528 |
Blood cholesterol increased | 32.38 | 11.38 | 13 | 73104 | 64591 | 70790736 |
Abdominal distension | 32.00 | 11.38 | 201 | 72916 | 104468 | 70750859 |
Neuromuscular block prolonged | 31.96 | 11.38 | 17 | 73100 | 966 | 70854361 |
Mucosal inflammation | 31.87 | 11.38 | 15 | 73102 | 67835 | 70787492 |
Pulmonary arterial pressure abnormal | 31.61 | 11.38 | 15 | 73102 | 667 | 70854660 |
Impaired healing | 31.19 | 11.38 | 19 | 73098 | 74355 | 70780972 |
Hyponatraemia | 30.94 | 11.38 | 75 | 73042 | 160012 | 70695315 |
Acute kidney injury | 30.69 | 11.38 | 327 | 72790 | 474297 | 70381030 |
N-terminal prohormone brain natriuretic peptide increased | 30.22 | 11.38 | 28 | 73089 | 3896 | 70851431 |
Central venous catheterisation | 30.10 | 11.38 | 25 | 73092 | 3008 | 70852319 |
Death | 29.89 | 11.38 | 712 | 72405 | 509349 | 70345978 |
Malignant neoplasm progression | 29.52 | 11.38 | 50 | 73067 | 121689 | 70733638 |
Cardiac ablation | 29.45 | 11.38 | 21 | 73096 | 2017 | 70853310 |
Irritable bowel syndrome | 29.39 | 11.38 | 8 | 73109 | 50842 | 70804485 |
Aggression | 29.20 | 11.38 | 7 | 73110 | 48439 | 70806888 |
Abdominal pain | 28.98 | 11.38 | 220 | 72897 | 341907 | 70513420 |
Chest discomfort | 28.70 | 11.38 | 223 | 72894 | 124158 | 70731169 |
Depression | 28.55 | 11.38 | 107 | 73010 | 198867 | 70656460 |
Pulmonary capillary haemangiomatosis | 28.39 | 11.38 | 8 | 73109 | 75 | 70855252 |
Subcutaneous emphysema | 28.22 | 11.38 | 19 | 73098 | 1663 | 70853664 |
Concomitant disease progression | 28.17 | 11.38 | 25 | 73092 | 3290 | 70852037 |
Cardiac pacemaker insertion | 27.94 | 11.38 | 31 | 73086 | 5341 | 70849986 |
Cognitive disorder | 27.83 | 11.38 | 14 | 73103 | 60942 | 70794385 |
Paracentesis | 27.80 | 11.38 | 17 | 73100 | 1261 | 70854066 |
Aspiration pleural cavity | 27.75 | 11.38 | 18 | 73099 | 1480 | 70853847 |
Catheter site scab | 27.61 | 11.38 | 10 | 73107 | 221 | 70855106 |
Pulmonary alveolar haemorrhage | 27.55 | 11.38 | 43 | 73074 | 10326 | 70845001 |
Device connection issue | 27.50 | 11.38 | 15 | 73102 | 896 | 70854431 |
Drug interaction | 27.47 | 11.38 | 256 | 72861 | 381185 | 70474142 |
Ventilation perfusion mismatch | 27.23 | 11.38 | 11 | 73106 | 330 | 70854997 |
Carbon dioxide increased | 27.11 | 11.38 | 20 | 73097 | 2025 | 70853302 |
Catheter removal | 27.03 | 11.38 | 13 | 73104 | 596 | 70854731 |
Osteonecrosis of jaw | 26.60 | 11.38 | 5 | 73112 | 40997 | 70814330 |
Interstitial lung disease | 26.58 | 11.38 | 192 | 72925 | 104493 | 70750834 |
Stevens-Johnson syndrome | 26.49 | 11.38 | 3 | 73114 | 35904 | 70819423 |
Nocturnal dyspnoea | 26.47 | 11.38 | 17 | 73100 | 1374 | 70853953 |
Drug resistance | 26.23 | 11.38 | 4 | 73113 | 38186 | 70817141 |
Catheter site warmth | 26.13 | 11.38 | 10 | 73107 | 259 | 70855068 |
Respiratory tract infection | 25.67 | 11.38 | 99 | 73018 | 42299 | 70813028 |
Presyncope | 25.67 | 11.38 | 91 | 73026 | 37347 | 70817980 |
Rash maculo-papular | 25.61 | 11.38 | 10 | 73107 | 50535 | 70804792 |
Tachypnoea | 25.40 | 11.38 | 76 | 73041 | 28562 | 70826765 |
Peripheral swelling | 25.36 | 11.38 | 363 | 72754 | 236200 | 70619127 |
Bronchitis | 25.29 | 11.38 | 207 | 72910 | 117036 | 70738291 |
Atrial flutter | 25.15 | 11.38 | 61 | 73056 | 20266 | 70835061 |
Injection site pruritus | 24.98 | 11.38 | 5 | 73112 | 39205 | 70816122 |
Heart rate increased | 24.87 | 11.38 | 191 | 72926 | 105957 | 70749370 |
Pulseless electrical activity | 24.84 | 11.38 | 47 | 73070 | 13168 | 70842159 |
Neuromuscular blockade | 24.79 | 11.38 | 12 | 73105 | 558 | 70854769 |
Acute right ventricular failure | 24.72 | 11.38 | 10 | 73107 | 301 | 70855026 |
Blister | 24.64 | 11.38 | 41 | 73076 | 100485 | 70754842 |
Thrombocytopenia | 24.63 | 11.38 | 145 | 72972 | 238965 | 70616362 |
Cardiomegaly | 24.54 | 11.38 | 68 | 73049 | 24477 | 70830850 |
Right ventricular dysfunction | 24.54 | 11.38 | 20 | 73097 | 2344 | 70852983 |
Neoplasm progression | 24.53 | 11.38 | 8 | 73109 | 45220 | 70810107 |
Hyperthermia malignant | 24.49 | 11.38 | 21 | 73096 | 2640 | 70852687 |
Rhabdomyolysis | 24.46 | 11.38 | 38 | 73079 | 95722 | 70759605 |
Product use in unapproved indication | 24.02 | 11.38 | 121 | 72996 | 207357 | 70647970 |
Accidental underdose | 23.98 | 11.38 | 13 | 73104 | 767 | 70854560 |
Congestive hepatopathy | 23.80 | 11.38 | 25 | 73092 | 4049 | 70851278 |
Pulmonary function test abnormal | 23.64 | 11.38 | 23 | 73094 | 3402 | 70851925 |
Tracheostomy | 23.51 | 11.38 | 15 | 73102 | 1199 | 70854128 |
Catheter site inflammation | 23.22 | 11.38 | 14 | 73103 | 1012 | 70854315 |
Rhinorrhoea | 23.19 | 11.38 | 132 | 72985 | 66239 | 70789088 |
Oxygen consumption | 22.98 | 11.38 | 7 | 73110 | 88 | 70855239 |
Bone marrow failure | 22.76 | 11.38 | 11 | 73106 | 48999 | 70806328 |
Sputum discoloured | 22.71 | 11.38 | 56 | 73061 | 18795 | 70836532 |
Multiple sclerosis relapse | 22.65 | 11.38 | 8 | 73109 | 43009 | 70812318 |
Wound | 22.63 | 11.38 | 42 | 73075 | 98690 | 70756637 |
Device leakage | 22.54 | 11.38 | 37 | 73080 | 9271 | 70846056 |
Neutrophil count decreased | 22.47 | 11.38 | 32 | 73085 | 83524 | 70771803 |
Colitis ulcerative | 22.30 | 11.38 | 4 | 73113 | 33919 | 70821408 |
Apnoea | 22.27 | 11.38 | 40 | 73077 | 10769 | 70844558 |
Hepatitis | 22.05 | 11.38 | 12 | 73105 | 49968 | 70805359 |
Colitis | 21.99 | 11.38 | 20 | 73097 | 63794 | 70791533 |
Cardiac disorder | 21.98 | 11.38 | 120 | 72997 | 59295 | 70796032 |
Psychotic disorder | 21.66 | 11.38 | 6 | 73111 | 37695 | 70817632 |
Seizure | 21.63 | 11.38 | 102 | 73015 | 177860 | 70677467 |
Cytomegalovirus infection | 21.62 | 11.38 | 7 | 73110 | 39751 | 70815576 |
Mediastinal effusion | 21.51 | 11.38 | 6 | 73111 | 54 | 70855273 |
Catheter site swelling | 21.43 | 11.38 | 16 | 73101 | 1650 | 70853677 |
Infusion site infection | 21.28 | 11.38 | 16 | 73101 | 1667 | 70853660 |
Gamma-glutamyltransferase increased | 21.26 | 11.38 | 106 | 73011 | 50579 | 70804748 |
Catheter site granuloma | 21.22 | 11.38 | 6 | 73111 | 57 | 70855270 |
Procedural complication | 21.14 | 11.38 | 32 | 73085 | 7482 | 70847845 |
Injection site swelling | 21.12 | 11.38 | 9 | 73108 | 43148 | 70812179 |
Feeling abnormal | 21.08 | 11.38 | 232 | 72885 | 142087 | 70713240 |
Hypertension | 20.74 | 11.38 | 200 | 72917 | 295833 | 70559494 |
Secretion discharge | 20.69 | 11.38 | 43 | 73074 | 12890 | 70842437 |
Red blood cell sedimentation rate increased | 20.67 | 11.38 | 7 | 73110 | 38635 | 70816692 |
Mouth ulceration | 20.63 | 11.38 | 5 | 73112 | 34344 | 70820983 |
Rhonchi | 20.59 | 11.38 | 22 | 73095 | 3633 | 70851694 |
Myocardial infarction | 20.49 | 11.38 | 99 | 73018 | 171546 | 70683781 |
Agranulocytosis | 20.37 | 11.38 | 8 | 73109 | 40290 | 70815037 |
Angioplasty | 20.33 | 11.38 | 16 | 73101 | 1784 | 70853543 |
Inappropriate schedule of product administration | 20.29 | 11.38 | 51 | 73066 | 107504 | 70747823 |
Pneumomediastinum | 20.26 | 11.38 | 21 | 73096 | 3349 | 70851978 |
Anaesthetic complication cardiac | 20.19 | 11.38 | 6 | 73111 | 69 | 70855258 |
Diabetic ketoacidosis | 20.11 | 11.38 | 4 | 73113 | 31508 | 70823819 |
Platelet transfusion | 20.08 | 11.38 | 17 | 73100 | 2101 | 70853226 |
Maternal exposure during pregnancy | 20.02 | 11.38 | 57 | 73060 | 115288 | 70740039 |
Infusion site erythema | 19.68 | 11.38 | 31 | 73086 | 7504 | 70847823 |
Right-to-left cardiac shunt | 19.65 | 11.38 | 8 | 73109 | 245 | 70855082 |
Tubulointerstitial nephritis | 19.50 | 11.38 | 5 | 73112 | 33071 | 70822256 |
Therapy non-responder | 19.48 | 11.38 | 141 | 72976 | 76774 | 70778553 |
Atrial fibrillation | 19.40 | 11.38 | 282 | 72835 | 184066 | 70671261 |
Uterine hypotonus | 19.31 | 11.38 | 6 | 73111 | 81 | 70855246 |
Decreased activity | 19.25 | 11.38 | 31 | 73086 | 7643 | 70847684 |
White blood cell count decreased | 19.25 | 11.38 | 100 | 73017 | 170041 | 70685286 |
Abdominal cavity drainage | 19.16 | 11.38 | 11 | 73106 | 726 | 70854601 |
Supraventricular tachycardia | 19.11 | 11.38 | 54 | 73063 | 19656 | 70835671 |
Blood pressure increased | 19.04 | 11.38 | 115 | 73002 | 188402 | 70666925 |
Neuropathy peripheral | 19.01 | 11.38 | 67 | 73050 | 126829 | 70728498 |
Ascites | 18.98 | 11.38 | 127 | 72990 | 67420 | 70787907 |
Emergency care | 18.96 | 11.38 | 12 | 73105 | 946 | 70854381 |
C-reactive protein increased | 18.90 | 11.38 | 55 | 73062 | 110462 | 70744865 |
Bronchospasm | 18.83 | 11.38 | 59 | 73058 | 22733 | 70832594 |
Hallucination | 18.78 | 11.38 | 31 | 73086 | 76229 | 70779098 |
Knee arthroplasty | 18.72 | 11.38 | 6 | 73111 | 34295 | 70821032 |
Product use issue | 18.58 | 11.38 | 109 | 73008 | 179828 | 70675499 |
Pulmonary artery banding | 18.51 | 11.38 | 4 | 73113 | 10 | 70855317 |
Iron deficiency anaemia | 18.40 | 11.38 | 59 | 73058 | 23013 | 70832314 |
Pulmonary artery dilatation | 18.34 | 11.38 | 9 | 73108 | 431 | 70854896 |
Glossoptosis | 17.98 | 11.38 | 7 | 73110 | 190 | 70855137 |
Pancreatitis | 17.86 | 11.38 | 23 | 73094 | 62645 | 70792682 |
Blood alkaline phosphatase increased | 17.64 | 11.38 | 112 | 73005 | 58409 | 70796918 |
Areflexia | 17.62 | 11.38 | 24 | 73093 | 5098 | 70850229 |
Upper respiratory tract inflammation | 17.56 | 11.38 | 21 | 73096 | 3921 | 70851406 |
Aspartate aminotransferase increased | 17.45 | 11.38 | 204 | 72913 | 126774 | 70728553 |
Rotavirus infection | 17.45 | 11.38 | 10 | 73107 | 658 | 70854669 |
Jugular vein distension | 17.44 | 11.38 | 13 | 73104 | 1337 | 70853990 |
Respiratory acidosis | 17.42 | 11.38 | 35 | 73082 | 10246 | 70845081 |
Eosinophilia | 17.32 | 11.38 | 10 | 73107 | 40309 | 70815018 |
Ventricular tachycardia | 17.32 | 11.38 | 79 | 73038 | 36344 | 70818983 |
Acute postoperative sialadenitis | 17.28 | 11.38 | 5 | 73112 | 52 | 70855275 |
Cerebral haemorrhage | 17.26 | 11.38 | 18 | 73099 | 53846 | 70801481 |
Brain hypoxia | 17.19 | 11.38 | 11 | 73106 | 884 | 70854443 |
Choking sensation | 17.16 | 11.38 | 20 | 73097 | 3635 | 70851692 |
Right ventricular enlargement | 16.72 | 11.38 | 9 | 73108 | 524 | 70854803 |
Cerebral infarction | 16.66 | 11.38 | 12 | 73105 | 42997 | 70812330 |
Right ventricular systolic pressure increased | 16.64 | 11.38 | 11 | 73106 | 934 | 70854393 |
Exposure during pregnancy | 16.23 | 11.38 | 42 | 73075 | 87675 | 70767652 |
Complication associated with device | 16.17 | 11.38 | 44 | 73073 | 15669 | 70839658 |
Burns second degree | 16.11 | 11.38 | 11 | 73106 | 985 | 70854342 |
Catheter site irritation | 16.03 | 11.38 | 9 | 73108 | 569 | 70854758 |
Urine output decreased | 15.97 | 11.38 | 46 | 73071 | 16924 | 70838403 |
Weight increased | 15.93 | 11.38 | 344 | 72773 | 241987 | 70613340 |
Argon plasma coagulation | 15.90 | 11.38 | 4 | 73113 | 23 | 70855304 |
Burns third degree | 15.88 | 11.38 | 8 | 73109 | 406 | 70854921 |
Exercise test abnormal | 15.86 | 11.38 | 5 | 73112 | 71 | 70855256 |
Pulmonary haemorrhage | 15.82 | 11.38 | 40 | 73077 | 13633 | 70841694 |
Jaundice | 15.77 | 11.38 | 17 | 73100 | 50091 | 70805236 |
Rales | 15.70 | 11.38 | 46 | 73071 | 17089 | 70838238 |
Sinus disorder | 15.59 | 11.38 | 49 | 73068 | 18910 | 70836417 |
Oral herpes | 15.58 | 11.38 | 3 | 73114 | 24183 | 70831144 |
Cold burn | 15.56 | 11.38 | 3 | 73114 | 3 | 70855324 |
Middle ear effusion | 15.56 | 11.38 | 15 | 73102 | 2194 | 70853133 |
Injection site bruising | 15.55 | 11.38 | 10 | 73107 | 38022 | 70817305 |
Rehabilitation therapy | 15.53 | 11.38 | 13 | 73104 | 1582 | 70853745 |
Lower respiratory tract infection | 15.52 | 11.38 | 61 | 73056 | 111852 | 70743475 |
Mechanical ventilation | 15.37 | 11.38 | 16 | 73101 | 2565 | 70852762 |
Respiratory syncytial virus infection | 15.36 | 11.38 | 28 | 73089 | 7627 | 70847700 |
Fibromyalgia | 15.34 | 11.38 | 16 | 73101 | 47858 | 70807469 |
Cholestasis | 15.34 | 11.38 | 16 | 73101 | 47856 | 70807471 |
Hepatocellular injury | 15.23 | 11.38 | 15 | 73102 | 46076 | 70809251 |
Hospice care | 15.19 | 11.38 | 29 | 73088 | 8176 | 70847151 |
Liver injury | 15.19 | 11.38 | 12 | 73105 | 41023 | 70814304 |
Cardioversion | 15.16 | 11.38 | 14 | 73103 | 1940 | 70853387 |
Dizziness postural | 15.11 | 11.38 | 33 | 73084 | 10235 | 70845092 |
Procedural hypotension | 15.09 | 11.38 | 14 | 73103 | 1952 | 70853375 |
Right ventricular dilatation | 15.04 | 11.38 | 13 | 73104 | 1652 | 70853675 |
Product dose omission issue | 15.04 | 11.38 | 311 | 72806 | 217157 | 70638170 |
PaO2/FiO2 ratio decreased | 14.98 | 11.38 | 4 | 73113 | 30 | 70855297 |
Emotional distress | 14.90 | 11.38 | 10 | 73107 | 37178 | 70818149 |
Inappropriate antidiuretic hormone secretion | 14.76 | 11.38 | 3 | 73114 | 23273 | 70832054 |
COVID-19 pneumonia | 14.72 | 11.38 | 53 | 73064 | 21916 | 70833411 |
Localised oedema | 14.70 | 11.38 | 27 | 73090 | 7394 | 70847933 |
Angioedema | 14.68 | 11.38 | 29 | 73088 | 66581 | 70788746 |
Barotrauma | 14.49 | 11.38 | 6 | 73111 | 192 | 70855135 |
Decreased appetite | 14.47 | 11.38 | 414 | 72703 | 304366 | 70550961 |
Agonal respiration | 14.35 | 11.38 | 3 | 73114 | 6 | 70855321 |
Airway burns | 14.35 | 11.38 | 3 | 73114 | 6 | 70855321 |
Poisoning | 14.17 | 11.38 | 3 | 73114 | 22619 | 70832708 |
Paradoxical embolism | 14.15 | 11.38 | 4 | 73113 | 38 | 70855289 |
Osteoarthritis | 14.11 | 11.38 | 35 | 73082 | 74112 | 70781215 |
Catheter site hypersensitivity | 13.91 | 11.38 | 5 | 73112 | 108 | 70855219 |
Incorrect dose administered | 13.90 | 11.38 | 30 | 73087 | 66689 | 70788638 |
Pulmonary fibrosis | 13.85 | 11.38 | 71 | 73046 | 34239 | 70821088 |
Accident | 13.79 | 11.38 | 26 | 73091 | 7265 | 70848062 |
Delayed recovery from anaesthesia | 13.75 | 11.38 | 12 | 73105 | 1545 | 70853782 |
Palmar-plantar erythrodysaesthesia syndrome | 13.73 | 11.38 | 7 | 73110 | 30240 | 70825087 |
Disease progression | 13.57 | 11.38 | 232 | 72885 | 156440 | 70698887 |
Breath sounds abnormal | 13.57 | 11.38 | 37 | 73080 | 13194 | 70842133 |
Paraesthesia | 13.56 | 11.38 | 91 | 73026 | 145446 | 70709881 |
Lung assist device therapy | 13.50 | 11.38 | 5 | 73112 | 118 | 70855209 |
Rash pruritic | 13.39 | 11.38 | 28 | 73089 | 62963 | 70792364 |
Terminal state | 13.36 | 11.38 | 20 | 73097 | 4632 | 70850695 |
Wheezing | 13.25 | 11.38 | 152 | 72965 | 94018 | 70761309 |
Blood creatine phosphokinase increased | 13.22 | 11.38 | 27 | 73090 | 61236 | 70794091 |
Chronic left ventricular failure | 13.18 | 11.38 | 9 | 73108 | 806 | 70854521 |
Pulmonary pain | 13.11 | 11.38 | 17 | 73100 | 3445 | 70851882 |
Drug level increased | 13.08 | 11.38 | 11 | 73106 | 36458 | 70818869 |
Thoracic cavity drainage | 13.05 | 11.38 | 6 | 73111 | 248 | 70855079 |
Ill-defined disorder | 12.80 | 11.38 | 23 | 73094 | 54718 | 70800609 |
Herpes zoster | 12.77 | 11.38 | 45 | 73072 | 85190 | 70770137 |
Large intestinal polypectomy | 12.66 | 11.38 | 6 | 73111 | 266 | 70855061 |
Vena cava filter insertion | 12.63 | 11.38 | 5 | 73112 | 142 | 70855185 |
Blood carbon monoxide increased | 12.63 | 11.38 | 3 | 73114 | 13 | 70855314 |
Systemic scleroderma | 12.55 | 11.38 | 10 | 73107 | 1135 | 70854192 |
Right ventricular hypertrophy | 12.52 | 11.38 | 11 | 73106 | 1429 | 70853898 |
Bradycardia | 12.46 | 11.38 | 189 | 72928 | 124426 | 70730901 |
Basal cell carcinoma | 12.29 | 11.38 | 10 | 73107 | 33688 | 70821639 |
Menstrual discomfort | 12.28 | 11.38 | 3 | 73114 | 15 | 70855312 |
Myelosuppression | 12.22 | 11.38 | 8 | 73109 | 30137 | 70825190 |
Atrial tachycardia | 12.15 | 11.38 | 17 | 73100 | 3703 | 70851624 |
Cardiorenal syndrome | 12.10 | 11.38 | 11 | 73106 | 1493 | 70853834 |
Plasma cell myeloma | 12.10 | 11.38 | 37 | 73080 | 73164 | 70782163 |
Catheter site erosion | 12.08 | 11.38 | 4 | 73113 | 67 | 70855260 |
Pulmonary vein stenosis | 12.08 | 11.38 | 5 | 73112 | 160 | 70855167 |
Oedematous kidney | 12.08 | 11.38 | 5 | 73112 | 160 | 70855167 |
Gastrointestinal tube insertion | 12.04 | 11.38 | 11 | 73106 | 1503 | 70853824 |
Gastrointestinal arteriovenous malformation | 12.04 | 11.38 | 9 | 73108 | 930 | 70854397 |
Frostbite | 11.99 | 11.38 | 5 | 73112 | 163 | 70855164 |
Head injury | 11.99 | 11.38 | 68 | 73049 | 34073 | 70821254 |
Puncture site infection | 11.97 | 11.38 | 4 | 73113 | 69 | 70855258 |
Retching | 11.96 | 11.38 | 40 | 73077 | 15939 | 70839388 |
Disturbance in attention | 11.96 | 11.38 | 16 | 73101 | 42878 | 70812449 |
Lung infiltration | 11.89 | 11.38 | 49 | 73068 | 21575 | 70833752 |
Oesophageal dilation procedure | 11.86 | 11.38 | 4 | 73113 | 71 | 70855256 |
Joint range of motion decreased | 11.85 | 11.38 | 6 | 73111 | 26020 | 70829307 |
Sopor | 11.75 | 11.38 | 9 | 73108 | 31258 | 70824069 |
Haematoma evacuation | 11.74 | 11.38 | 6 | 73111 | 314 | 70855013 |
Sinus congestion | 11.71 | 11.38 | 42 | 73075 | 17331 | 70837996 |
Proteinuria | 11.64 | 11.38 | 8 | 73109 | 29366 | 70825961 |
Upper respiratory tract infection | 11.63 | 11.38 | 129 | 72988 | 79145 | 70776182 |
Nasal operation | 11.58 | 11.38 | 5 | 73112 | 178 | 70855149 |
Stress cardiomyopathy | 11.57 | 11.38 | 29 | 73088 | 9833 | 70845494 |
Product supply issue | 11.55 | 11.38 | 11 | 73106 | 1584 | 70853743 |
Right ventricular systolic pressure | 11.55 | 11.38 | 3 | 73114 | 20 | 70855307 |
Lung squamous cell carcinoma stage I | 11.55 | 11.38 | 3 | 73114 | 20 | 70855307 |
Blood triglycerides increased | 11.54 | 11.38 | 3 | 73114 | 19661 | 70835666 |
Nasal discomfort | 11.51 | 11.38 | 19 | 73098 | 4782 | 70850545 |
Catheter site vesicles | 11.51 | 11.38 | 6 | 73111 | 327 | 70855000 |
Sedation | 11.50 | 11.38 | 19 | 73098 | 46712 | 70808615 |
Rhinovirus infection | 11.50 | 11.38 | 23 | 73094 | 6710 | 70848617 |
Multiple allergies | 11.49 | 11.38 | 25 | 73092 | 7735 | 70847592 |
Cardiac septal defect repair | 11.42 | 11.38 | 3 | 73114 | 21 | 70855306 |
Ventricular extrasystoles | 11.40 | 11.38 | 43 | 73074 | 18183 | 70837144 |
Polypectomy | 11.38 | 11.38 | 9 | 73108 | 1010 | 70854317 |
None
Source | Code | Description |
---|---|---|
ATC | V03AN04 | VARIOUS ALL OTHER THERAPEUTIC PRODUCTS ALL OTHER THERAPEUTIC PRODUCTS Medical gases |
CHEBI has role | CHEBI:77974 | food packaging gases |
CHEBI has role | CHEBI:78017 | food propellants |
CHEBI has role | CHEBI:33937 | macronutrients |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Persistent pulmonary hypertension of the newborn | indication | 233815004 | DOID:13042 |
Methemoglobinemia | contraindication | 38959009 | DOID:10783 |
Left heart failure | contraindication | 85232009 | |
Congenital Heart Defect Requiring Open Patent Ductus Arteriosus | contraindication |
None
Product | Applicant | Ingredients |
---|---|---|
None (Med Gas) | Air Liquide Industrial U.S. L.P. | 2 |
None (Med Gas) | Air Liquide Large Industries U.S. L.P. | 2 |
None (Med Gas) | Messer LLC | 2 |
None (Med Gas) | Norco Inc. | 2 |
None (Med Gas) | Messer Gas Puerto Rico Inc. | 2 |
None (Med Gas) | Air Liquide America L.P. | 2 |
None (Med Gas) | Airgas Merchant Gases LLC | 2 |
None (Med Gas) | Praxair Inc. | 2 |
None (Med Gas) | Aspen Air, US Corp | 2 |
None (Med Gas) | Air Products and Chemicals Inc. | 2 |
None (Med Gas) | Matheson Tri-Gas Inc. | 2 |
None (Med Gas) | Praxair Canada Inc. | 2 |
None (Med Gas) | Airgas USA LLC | 2 |
None
None
None
None
ID | Source |
---|---|
4019163 | VUID |
N0000147408 | NUI |
D00083 | KEGG_DRUG |
4019163 | VANDF |
C0028158 | UMLSCUI |
CHEBI:25555 | CHEBI |
NGN | PDB_CHEM_ID |
CHEMBL142438 | ChEMBL_ID |
D009584 | MESH_DESCRIPTOR_UI |
DB09152 | DRUGBANK_ID |
N762921K75 | UNII |
947 | PUBCHEM_CID |
7456 | RXNORM |
002515 | NDDF |
36012007 | SNOMEDCT_US |
767123001 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10006-005 | GAS | 99 L | RESPIRATORY (INHALATION) | unapproved medical gas | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10014-002 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10014-002 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10018-9502 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10167-400 | GAS | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10167-400 | GAS | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10218-102 | GAS | 995 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10218-102 | GAS | 995 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10221-002 | GAS | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10221-002 | GAS | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10252-002 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10252-002 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10297-002 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10297-200 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10297-200 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10304-601 | GAS | 999 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10304-601 | GAS | 999 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10412-0095 | GAS | 99.50 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10412-0095 | GAS | 99.50 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10451-003 | GAS | 992 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10451-003 | GAS | 992 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10526-003 | LIQUID | 990 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10526-006 | LIQUID | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10526-006 | LIQUID | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10671-020 | GAS | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10671-021 | LIQUID | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10671-022 | LIQUID | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
NITROGEN | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10671-023 | LIQUID | 99 L | RESPIRATORY (INHALATION) | NDA | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10678-002 | GAS | 992 mL | RESPIRATORY (INHALATION) | unapproved medical gas | 1 sections |
Nitrogen | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10690-002 | GAS | 990 mL | RESPIRATORY (INHALATION) | NDA | 1 sections |