oxygen Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4235 7782-44-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxygen
  • molecular oxygen
  • oxygen molecule
An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
  • Molecular weight: 32.00
  • Formula: O2
  • CLOGP:
  • LIPINSKI: None
  • HAC: 2
  • HDO: 0
  • TPSA: 34.14
  • ALOGS:
  • ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Dyspnoea 873.50 11.90 1805 49291 513743 46121223
Pulmonary arterial hypertension 604.51 11.90 368 50728 25560 46609406
Oxygen saturation decreased 561.66 11.90 521 50575 68643 46566323
Pulmonary hypertension 459.25 11.90 352 50744 35641 46599325
Oxygen consumption increased 437.80 11.90 161 50935 3502 46631464
Right ventricular failure 397.15 11.90 237 50859 15856 46619110
Dyspnoea exertional 360.80 11.90 354 50742 49935 46585031
Fluid retention 352.64 11.90 352 50744 50694 46584272
Chronic obstructive pulmonary disease 269.94 11.90 324 50772 57309 46577657
Drug ineffective 264.58 11.90 214 50882 677624 45957342
Hypoxia 260.28 11.90 302 50794 51536 46583430
Oxygen therapy 208.59 11.90 78 51018 1779 46633187
Respiratory failure 198.50 11.90 365 50731 94451 46540515
Fluid overload 188.58 11.90 188 50908 26997 46607969
Transfusion 181.00 11.90 135 50961 13096 46621870
Rheumatoid arthritis 170.51 11.90 29 51067 240186 46394780
Nasal congestion 160.57 11.90 229 50867 47884 46587082
Pain in jaw 152.83 11.90 199 50897 38173 46596793
Pneumonia 148.54 11.90 806 50290 375514 46259452
Oedema peripheral 136.15 11.90 434 50662 159272 46475694
Acute respiratory failure 134.99 11.90 163 50933 28975 46605991
Toxicity to various agents 125.43 11.90 38 51058 211728 46423238
Oedema 122.77 11.90 244 50852 66827 46568139
Drug hypersensitivity 114.78 11.90 62 51034 243763 46391203
Cardiac failure 109.85 11.90 259 50837 79689 46555277
Cough 104.34 11.90 513 50583 229736 46405230
Concomitant disease aggravated 102.42 11.90 78 51018 7804 46627162
Pulmonary oedema 102.16 11.90 193 50903 50912 46584054
Productive cough 100.72 11.90 191 50905 50524 46584442
Pulmonary arterial pressure increased 100.64 11.90 56 51040 3276 46631690
Chest pain 99.33 11.90 419 50677 175905 46459061
Catheter site erythema 86.29 11.90 54 51042 3929 46631037
Catheter site pruritus 78.82 11.90 40 51056 1939 46633027
Treatment failure 76.22 11.90 7 51089 93080 46541886
Neutropenia 75.65 11.90 31 51065 143173 46491793
Lung transplant 74.99 11.90 44 51052 2848 46632118
Scleroderma 74.18 11.90 52 51044 4577 46630389
Catheter management 71.10 11.90 42 51054 2753 46632213
Haemoptysis 70.74 11.90 113 50983 26076 46608890
Epistaxis 70.21 11.90 191 50905 64114 46570852
Rash 69.05 11.90 183 50913 356329 46278637
Headache 68.30 11.90 811 50285 477541 46157425
Syncope 65.23 11.90 257 50839 104546 46530420
Hypercapnia 65.05 11.90 48 51048 4578 46630388
Brain natriuretic peptide increased 62.59 11.90 47 51049 4603 46630363
Condition aggravated 62.27 11.90 470 50626 244582 46390384
Alopecia 59.57 11.90 54 51042 162360 46472606
Dependence on oxygen therapy 59.55 11.90 20 51076 329 46634637
Off label use 59.35 11.90 215 50881 379626 46255340
Catheterisation cardiac 59.18 11.90 43 51053 4004 46630962
Drug abuse 57.02 11.90 3 51093 63405 46571561
Blood pressure decreased 56.72 11.90 164 50932 56995 46577971
Drug intolerance 54.99 11.90 48 51048 147001 46487965
Therapeutic product effect decreased 52.25 11.90 13 51083 82588 46552378
Device alarm issue 52.19 11.90 27 51069 1363 46633603
Arthropathy 48.65 11.90 16 51080 84684 46550282
Injection site erythema 48.48 11.90 11 51085 74416 46560550
Cardiac failure congestive 48.47 11.90 214 50882 91536 46543430
Musculoskeletal stiffness 47.39 11.90 24 51072 97969 46536997
Cor pulmonale 46.31 11.90 28 51068 1915 46633051
Exercise tolerance decreased 46.06 11.90 39 51057 4538 46630428
Joint swelling 46.05 11.90 69 51027 166004 46468962
Catheter site pain 45.82 11.90 36 51060 3770 46631196
Palpitations 45.72 11.90 216 50880 95043 46539923
Suicide attempt 45.42 11.90 4 51092 55032 46579934
Injection site pain 45.10 11.90 31 51065 107121 46527845
Cyanosis 44.63 11.90 70 51026 15901 46619065
Pleural effusion 44.20 11.90 194 50902 82758 46552208
Thermal burn 43.91 11.90 39 51057 4838 46630128
Pulmonary veno-occlusive disease 43.78 11.90 21 51075 900 46634066
Intentional overdose 43.52 11.90 9 51087 64935 46570031
Unevaluable event 43.43 11.90 130 50966 46045 46588921
Psoriasis 43.16 11.90 16 51080 78588 46556378
Hypotension 43.14 11.90 416 50680 232173 46402793
Air embolism 41.31 11.90 14 51082 237 46634729
Chronic respiratory failure 41.23 11.90 25 51071 1719 46633247
Arthralgia 40.95 11.90 233 50863 364370 46270596
Pericardial effusion 40.90 11.90 88 51008 25455 46609511
Transplant evaluation 40.68 11.90 21 51075 1055 46633911
Flushing 40.62 11.90 159 50937 64455 46570511
Lung disorder 39.86 11.90 121 50975 43183 46591783
Device related infection 39.00 11.90 77 51019 20964 46614002
Catheter site infection 38.85 11.90 36 51060 4717 46630249
Catheter site discharge 38.40 11.90 25 51071 1947 46633019
Catheter site rash 38.31 11.90 18 51078 736 46634230
Overdose 37.26 11.90 34 51062 101945 46533021
Dyspnoea at rest 36.98 11.90 31 51065 3557 46631409
Pulmonary hypertensive crisis 36.75 11.90 12 51084 180 46634786
Dizziness 36.32 11.90 548 50548 339866 46295100
Pruritus 35.94 11.90 140 50956 242212 46392754
Pulmonary arterial pressure abnormal 35.93 11.90 15 51081 461 46634505
Orthopnoea 35.92 11.90 38 51058 5842 46629124
Injection site reaction 35.65 11.90 5 51091 47844 46587122
Oxygen saturation abnormal 35.53 11.90 27 51069 2691 46632275
Chest discomfort 35.12 11.90 193 50903 90076 46544890
Therapeutic product effect incomplete 35.08 11.90 21 51075 78132 46556834
Malaise 34.09 11.90 530 50566 330702 46304264
Febrile neutropenia 34.03 11.90 32 51064 94595 46540371
Respiratory distress 33.03 11.90 93 51003 31823 46603143
Hospitalisation 32.07 11.90 146 50950 63239 46571727
Infusion site pain 32.07 11.90 47 51049 10060 46624906
Urticaria 31.69 11.90 50 51046 117842 46517124
Presyncope 31.16 11.90 77 51019 24377 46610589
Aspiration pleural cavity 30.97 11.90 16 51080 805 46634161
Central venous catheterisation 30.67 11.90 22 51074 2008 46632958
Oxygen consumption 30.53 11.90 9 51087 94 46634872
Suicidal ideation 30.08 11.90 12 51084 56370 46578596
Left ventricular failure 30.05 11.90 32 51064 4958 46630008
Glossodynia 30.04 11.90 6 51090 44367 46590599
Leukopenia 29.79 11.90 19 51077 68324 46566642
Pain 29.63 11.90 357 50739 476591 46158375
Nasal dryness 29.56 11.90 27 51069 3473 46631493
Peripheral swelling 29.40 11.90 283 50813 157788 46477178
Device occlusion 28.74 11.90 34 51062 5911 46629055
Depression 28.71 11.90 93 51003 170011 46464955
Emphysema 28.58 11.90 42 51054 9012 46625954
Frostbite 28.01 11.90 6 51090 13 46634953
Hand deformity 27.25 11.90 3 51093 34571 46600395
Exposure during pregnancy 27.13 11.90 48 51048 108164 46526802
Device leakage 26.46 11.90 31 51065 5334 46629632
Cardiac pacemaker insertion 26.41 11.90 26 51070 3673 46631293
Cardiac failure acute 26.26 11.90 38 51058 8040 46626926
Paracentesis 26.15 11.90 15 51081 930 46634036
Pulmonary congestion 26.04 11.90 53 51043 14746 46620220
Systemic lupus erythematosus 25.93 11.90 20 51076 65160 46569806
Stomatitis 25.87 11.90 22 51074 68275 46566691
Catheter placement 24.76 11.90 19 51077 1922 46633044
Bronchitis 24.48 11.90 199 50897 105780 46529186
Infusion related reaction 24.39 11.90 46 51050 101162 46533804
Therapy non-responder 24.04 11.90 99 50997 41053 46593913
Injection site pruritus 23.72 11.90 7 51089 39736 46595230
Maternal exposure during pregnancy 23.51 11.90 48 51048 102501 46532465
Abdominal distension 22.86 11.90 148 50948 73203 46561763
Injection site swelling 22.49 11.90 8 51088 40319 46594647
N-terminal prohormone brain natriuretic peptide increased 22.38 11.90 17 51079 1694 46633272
Walking distance test abnormal 22.19 11.90 11 51085 507 46634459
Hypersensitivity 22.15 11.90 87 51009 150234 46484732
Death 21.71 11.90 500 50596 335048 46299918
Catheter site swelling 21.54 11.90 15 51081 1306 46633660
Atrial flutter 21.38 11.90 37 51059 9111 46625855
Paraesthesia 21.37 11.90 62 51034 117375 46517591
Rhinorrhoea 21.35 11.90 106 50990 47559 46587407
Wheezing 21.33 11.90 115 50981 53271 46581695
Catheter site scab 21.33 11.90 8 51088 184 46634782
Rales 21.28 11.90 38 51058 9593 46625373
Disease progression 20.84 11.90 171 50925 91129 46543837
Multiple sclerosis relapse 20.83 11.90 10 51086 42115 46592851
Interstitial lung disease 20.74 11.90 115 50981 53834 46581132
Cardiac disorder 20.69 11.90 99 50997 43759 46591207
Osteonecrosis of jaw 20.64 11.90 6 51090 34396 46600570
Pulmonary pain 20.49 11.90 16 51080 1660 46633306
Neuromuscular blockade 20.46 11.90 9 51087 315 46634651
Sputum discoloured 20.43 11.90 44 51052 12734 46622232
Nocturnal dyspnoea 20.14 11.90 13 51083 998 46633968
Malignant neoplasm progression 19.96 11.90 25 51071 64901 46570065
Cardiac ablation 19.84 11.90 14 51082 1245 46633721
Ascites 19.81 11.90 86 51010 36498 46598468
Accident 19.57 11.90 26 51070 5078 46629888
Coma 19.52 11.90 21 51075 58328 46576638
Device connection issue 19.42 11.90 11 51085 666 46634300
Anaesthetic complication 19.35 11.90 16 51080 1801 46633165
Concomitant disease progression 18.89 11.90 17 51079 2145 46632821
Cardiac arrest 18.89 11.90 166 50930 90233 46544733
Weight increased 18.74 11.90 268 50828 164205 46470761
Pulmonary function test decreased 18.72 11.90 22 51074 3798 46631168
Uterine hypotonus 18.44 11.90 6 51090 89 46634877
Paradoxical embolism 18.38 11.90 5 51091 38 46634928
Injection site bruising 18.34 11.90 8 51088 35628 46599338
Stent placement 18.29 11.90 21 51075 3535 46631431
Gamma-glutamyltransferase increased 18.26 11.90 76 51020 31664 46603302
Hepatic enzyme increased 18.14 11.90 39 51057 81748 46553218
Bone marrow failure 18.12 11.90 5 51091 29664 46605302
Infusion site infection 17.99 11.90 14 51082 1445 46633521
Rhabdomyolysis 17.79 11.90 12 51084 41897 46593069
Hepatotoxicity 17.74 11.90 3 51093 25006 46609960
Hypoglycaemia 17.70 11.90 20 51076 54329 46580637
Product use in unapproved indication 17.66 11.90 46 51050 90227 46544739
Seizure 17.63 11.90 72 51024 122982 46511984
Accidental underdose 17.61 11.90 10 51086 608 46634358
Blood cholesterol increased 17.61 11.90 11 51085 40002 46594964
Heart rate increased 17.57 11.90 141 50955 74650 46560316
Hyperandrogenism 17.42 11.90 6 51090 107 46634859
Subcutaneous emphysema 17.38 11.90 11 51085 816 46634150
Hyponatraemia 17.36 11.90 55 51041 101277 46533689
Congestive hepatopathy 17.03 11.90 17 51079 2441 46632525
Ventilation perfusion mismatch 16.71 11.90 7 51089 217 46634749
Localised oedema 16.70 11.90 24 51072 5045 46629921
Bladder agenesis 16.64 11.90 6 51090 123 46634843
Rash maculo-papular 16.47 11.90 5 51091 27869 46607097
Cognitive disorder 16.42 11.90 10 51086 36873 46598093
Blood iron decreased 16.37 11.90 37 51059 11060 46623906
Cardioversion 16.30 11.90 12 51084 1140 46633826
Cloacal exstrophy 16.29 11.90 6 51090 131 46634835
Drug reaction with eosinophilia and systemic symptoms 16.24 11.90 6 51090 29542 46605424
Herpes zoster 16.21 11.90 31 51065 67841 46567125
Carbon dioxide increased 16.10 11.90 12 51084 1162 46633804
Platelet transfusion 16.08 11.90 10 51086 719 46634247
Genitalia external ambiguous 16.04 11.90 6 51090 137 46634829
Congenital ectopic bladder 15.97 11.90 5 51091 65 46634901
Argon plasma coagulation 15.97 11.90 4 51092 21 46634945
Abdominal cavity drainage 15.95 11.90 8 51088 378 46634588
Right ventricular systolic pressure increased 15.89 11.90 9 51087 545 46634421
Thrombocytopenia 15.77 11.90 78 51018 126503 46508463
Angioedema 15.74 11.90 12 51084 39330 46595636
Lung assist device therapy 15.70 11.90 5 51091 69 46634897
Red blood cell sedimentation rate increased 15.69 11.90 3 51093 22886 46612080
Pulmonary fibrosis 15.62 11.90 53 51043 20039 46614927
Enlarged clitoris 15.53 11.90 6 51090 150 46634816
Acute postoperative sialadenitis 15.52 11.90 4 51092 24 46634942
Lipodystrophy acquired 15.51 11.90 13 51083 1492 46633474
Tracheostomy 15.49 11.90 9 51087 572 46634394
Psychotic disorder 15.43 11.90 3 51093 22618 46612348
Right ventricular dysfunction 15.41 11.90 13 51083 1505 46633461
Cold burn 15.38 11.90 3 51093 3 46634963
Blood pressure increased 15.24 11.90 79 51017 126587 46508379
Neuropathy peripheral 15.11 11.90 50 51046 90843 46544123
Osteoarthritis 15.10 11.90 28 51068 61997 46572969
Tachypnoea 15.02 11.90 42 51054 14309 46620657
Haematocrit decreased 15.02 11.90 77 51019 34980 46599986
Meconium stain 14.93 11.90 6 51090 167 46634799
Middle ear effusion 14.87 11.90 14 51082 1871 46633095
Iron deficiency anaemia 14.83 11.90 47 51049 17159 46617807
Echocardiogram 14.75 11.90 4 51092 30 46634936
Gout 14.72 11.90 36 51060 11320 46623646
Drug interaction 14.55 11.90 147 50949 202947 46432019
Terminal state 14.55 11.90 15 51081 2239 46632727
Hospice care 14.50 11.90 23 51073 5272 46629694
Jugular vein distension 14.41 11.90 10 51086 866 46634100
Respiratory tract infection 14.39 11.90 68 51028 29904 46605062
Barotrauma 14.35 11.90 6 51090 185 46634781
Infusion site erythema 14.20 11.90 28 51068 7614 46627352
Mobility decreased 14.19 11.90 28 51068 60566 46574400
Right ventricular dilatation 14.02 11.90 10 51086 904 46634062
Catheter site haemorrhage 13.94 11.90 16 51080 2693 46632273
Gastrointestinal disorder congenital 13.93 11.90 5 51091 101 46634865
Dizziness exertional 13.88 11.90 7 51089 335 46634631
Therapy change 13.79 11.90 22 51074 5068 46629898
Breath sounds abnormal 13.76 11.90 28 51068 7787 46627179
Wrong technique in product usage process 13.76 11.90 24 51072 54398 46580568
Rehabilitation therapy 13.76 11.90 11 51085 1181 46633785
Oxygen consumption decreased 13.75 11.90 6 51090 206 46634760
Tethered cord syndrome 13.61 11.90 6 51090 211 46634755
Idiopathic pulmonary fibrosis 13.60 11.90 12 51084 1476 46633490
Catheter site warmth 13.59 11.90 6 51090 212 46634754
Aggression 13.58 11.90 4 51092 22740 46612226
Pulmonary artery banding 13.57 11.90 3 51093 8 46634958
Abdominal pain 13.54 11.90 174 50922 229857 46405109
Upper respiratory tract inflammation 13.53 11.90 16 51080 2779 46632187
Pneumomediastinum 13.53 11.90 11 51085 1210 46633756
Pulmonary haemorrhage 13.52 11.90 25 51071 6480 46628486
Injury 13.48 11.90 17 51079 44010 46590956
Burns third degree 13.43 11.90 6 51090 218 46634748
PO2 decreased 13.36 11.90 12 51084 1510 46633456
Diverticulitis 13.31 11.90 10 51086 33029 46601937
Urinary retention 13.17 11.90 6 51090 26055 46608911
Congenital genital malformation 13.17 11.90 5 51091 119 46634847
Product use issue 13.16 11.90 56 51040 94588 46540378
Supraventricular tachycardia 13.08 11.90 38 51058 13232 46621734
No adverse event 12.99 11.90 11 51085 34220 46600746
Gastrointestinal arteriovenous malformation 12.92 11.90 8 51088 571 46634395
Therapeutic response decreased 12.86 11.90 17 51079 43128 46591838
Glossoptosis 12.78 11.90 4 51092 52 46634914
Increased bronchial secretion 12.76 11.90 12 51084 1602 46633364
Aspartate aminotransferase increased 12.74 11.90 137 50959 78563 46556403
Adverse drug reaction 12.70 11.90 18 51078 44344 46590622
Hepatitis 12.66 11.90 10 51086 32205 46602761
Hallucination 12.65 11.90 22 51074 49929 46585037
Apnoea 12.58 11.90 26 51070 7313 46627653
Emergency care 12.43 11.90 9 51087 833 46634133
Biopsy liver 12.43 11.90 7 51089 419 46634547
White blood cell count decreased 12.40 11.90 72 51024 112159 46522807
Mouth ulceration 12.33 11.90 7 51089 26825 46608141
Haemoglobin decreased 12.33 11.90 204 50892 128745 46506221
Atrial fibrillation 12.27 11.90 170 50926 103420 46531546
Hypozincaemia 12.27 11.90 3 51093 14 46634952
Neoplasm progression 12.21 11.90 7 51089 26676 46608290
Systemic scleroderma 12.21 11.90 9 51087 857 46634109
Vascular cauterisation 12.19 11.90 4 51092 61 46634905
Pneumocephalus 12.18 11.90 5 51091 147 46634819
Gastrointestinal malformation 12.15 11.90 5 51091 148 46634818
C-reactive protein increased 12.12 11.90 29 51067 58561 46576405
Lung squamous cell carcinoma stage I 12.10 11.90 3 51093 15 46634951
Neutrophil count decreased 12.06 11.90 18 51078 43408 46591558
Mucosal inflammation 11.99 11.90 15 51081 38961 46596005

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Dyspnoea 372.38 12.72 831 23751 332464 29595432
Oxygen saturation decreased 352.74 12.72 289 24293 43151 29884745
Pulmonary arterial hypertension 263.67 12.72 136 24446 9165 29918731
Hypoxia 199.02 12.72 220 24362 47634 29880262
Right ventricular failure 189.63 12.72 104 24478 7932 29919964
Oxygen consumption increased 175.41 12.72 58 24524 1230 29926666
Chronic obstructive pulmonary disease 174.65 12.72 202 24380 45924 29881972
Pulmonary hypertension 155.00 12.72 127 24455 18909 29908987
Respiratory failure 115.66 12.72 255 24327 100387 29827509
Fluid retention 110.91 12.72 119 24463 24879 29903017
Concomitant disease aggravated 109.05 12.72 62 24520 5067 29922829
Thermal burn 93.60 12.72 43 24539 2242 29925654
Acute respiratory failure 92.41 12.72 110 24472 25740 29902156
Dyspnoea exertional 90.98 12.72 128 24454 35302 29892594
Pneumonia 82.95 12.72 512 24070 333794 29594102
Oxygen therapy 73.17 12.72 26 24556 689 29927207
Transfusion 65.40 12.72 52 24530 7409 29920487
Accidental underdose 60.36 12.72 19 24563 342 29927554
Nasal congestion 59.84 12.72 75 24507 18491 29909405
Pain in jaw 59.48 12.72 61 24521 12095 29915801
Toxicity to various agents 59.40 12.72 36 24546 177147 29750749
Completed suicide 57.57 12.72 7 24575 99485 29828411
Subacute combined cord degeneration 51.68 12.72 14 24568 144 29927752
Cough 50.11 12.72 220 24362 125422 29802474
Hypercapnia 47.80 12.72 33 24549 3791 29924105
Pulmonary oedema 47.68 12.72 109 24473 43866 29884030
Pulmonary arterial pressure increased 45.92 12.72 21 24561 1083 29926813
Accident 44.74 12.72 31 24551 3582 29924314
Fluid overload 43.20 12.72 65 24517 19027 29908869
Drug abuse 42.38 12.72 8 24574 82064 29845832
Respiratory distress 41.74 12.72 87 24495 32885 29895011
Brain natriuretic peptide increased 39.44 12.72 30 24552 4005 29923891
Condition aggravated 39.00 12.72 219 24363 137647 29790249
Cerebral artery thrombosis 38.80 12.72 15 24567 506 29927390
Burns third degree 38.19 12.72 11 24571 144 29927752
Oedema 37.47 12.72 98 24484 42895 29885001
Blood pressure decreased 33.81 12.72 100 24482 46975 29880921
Idiopathic pulmonary fibrosis 32.78 12.72 27 24555 4042 29923854
Pulmonary function test abnormal 32.73 12.72 18 24564 1378 29926518
Brain scan abnormal 32.22 12.72 14 24568 639 29927257
Pneumothorax 30.91 12.72 51 24531 16142 29911754
Catheter management 30.80 12.72 15 24567 892 29927004
Cor pulmonale 30.45 12.72 14 24568 731 29927165
Lung transplant 29.92 12.72 19 24563 1897 29925999
Catheter site erythema 29.67 12.72 16 24566 1178 29926718
Drug ineffective 29.37 12.72 162 24420 340225 29587671
Neuromuscular block prolonged 28.82 12.72 11 24571 358 29927538
Oedema peripheral 27.86 12.72 165 24417 105667 29822229
Cyanosis 27.51 12.72 41 24541 11894 29916002
Neutropenia 26.79 12.72 40 24542 128500 29799396
Mechanical ventilation 26.78 12.72 17 24565 1697 29926199
Air embolism 26.65 12.72 8 24574 122 29927774
Cardiac failure 26.60 12.72 137 24445 83281 29844615
Burns second degree 25.28 12.72 10 24572 359 29927537
Transplant evaluation 24.99 12.72 11 24571 518 29927378
Drug interaction 23.83 12.72 84 24498 199484 29728412
Rheumatoid arthritis 23.56 12.72 3 24579 41194 29886702
Pulmonary veno-occlusive disease 23.34 12.72 10 24572 441 29927455
Catheter removal 22.95 12.72 8 24574 200 29927696
Catheterisation cardiac 22.72 12.72 17 24565 2214 29925682
Catheter placement 21.69 12.72 11 24571 714 29927182
Intentional overdose 21.50 12.72 4 24578 41477 29886419
Pulmonary fibrosis 21.36 12.72 43 24539 15847 29912049
Emphysema 21.25 12.72 32 24550 9370 29918526
Subcutaneous emphysema 21.05 12.72 12 24570 985 29926911
Hyperthermia malignant 21.00 12.72 15 24567 1819 29926077
Catheter site haemorrhage 20.90 12.72 16 24566 2156 29925740
Carbon dioxide increased 20.74 12.72 12 24570 1013 29926883
Haemoptysis 20.42 12.72 64 24518 31014 29896882
Catheter site pain 20.28 12.72 12 24570 1056 29926840
Anaesthetic complication 20.27 12.72 12 24570 1057 29926839
Catheter site pruritus 19.84 12.72 8 24574 302 29927594
Areflexia 19.76 12.72 17 24565 2702 29925194
Acute kidney injury 19.59 12.72 138 24444 273704 29654192
Rotavirus infection 19.27 12.72 8 24574 326 29927570
Catheter site granuloma 18.89 12.72 4 24578 12 29927884
Chronic respiratory failure 18.83 12.72 12 24570 1206 29926690
Barotrauma 18.49 12.72 5 24577 51 29927845
Ventricular tachycardia 18.39 12.72 52 24530 23810 29904086
Dyspnoea at rest 18.34 12.72 16 24566 2590 29925306
Catheter site discharge 18.33 12.72 9 24573 545 29927351
Frostbite 18.32 12.72 5 24577 53 29927843
Aggression 18.21 12.72 4 24578 36903 29890993
Ventilation perfusion mismatch 17.68 12.72 5 24577 61 29927835
Walking distance test abnormal 17.60 12.72 6 24576 140 29927756
Pulmonary capillary haemangiomatosis 17.44 12.72 4 24578 19 29927877
Lung disorder 17.28 12.72 61 24521 31408 29896488
Myocardial infarction 16.97 12.72 50 24532 125575 29802321
Respiratory acidosis 16.88 12.72 19 24563 4183 29923713
Leukopenia 16.66 12.72 13 24569 56146 29871750
Treatment failure 16.62 12.72 4 24578 34675 29893221
Pulmonary hypertensive crisis 16.57 12.72 6 24576 168 29927728
Occupational exposure to product 16.55 12.72 7 24575 299 29927597
Anaemia vitamin B12 deficiency 16.46 12.72 7 24575 303 29927593
Thoracic cavity drainage 16.09 12.72 6 24576 183 29927713
Pulse pressure decreased 16.00 12.72 6 24576 186 29927710
Overdose 15.91 12.72 28 24554 84309 29843587
Anaesthetic complication cardiac 15.89 12.72 4 24578 30 29927866
Procedural complication 15.83 12.72 19 24563 4478 29923418
Cardiac failure congestive 15.81 12.72 121 24461 84286 29843610
Catheter site warmth 15.77 12.72 4 24578 31 29927865
PaO2/FiO2 ratio decreased 15.66 12.72 4 24578 32 29927864
Complication associated with device 15.16 12.72 21 24561 5699 29922197
Apnoea 15.15 12.72 22 24560 6236 29921660
Headache 14.93 12.72 221 24361 182085 29745811
Hyponatraemia 14.89 12.72 20 24562 67182 29860714
Pulmonary function test decreased 14.88 12.72 18 24564 4277 29923619
Peripheral swelling 14.65 12.72 93 24489 60981 29866915
Cardiac arrest 14.64 12.72 128 24454 92722 29835174
Suicide attempt 14.45 12.72 6 24576 36691 29891205
Catheter site inflammation 14.32 12.72 6 24576 250 29927646
Epistaxis 14.17 12.72 83 24499 52898 29874998
Interstitial lung disease 14.03 12.72 91 24491 60106 29867790
White blood cell count decreased 13.98 12.72 30 24552 83917 29843979
Pulmonary congestion 13.91 12.72 31 24551 12256 29915640
Productive cough 13.89 12.72 55 24527 29898 29897998
Thrombocytopenia 13.01 12.72 63 24519 136981 29790915

Pharmacologic Action:

SourceCodeDescription
ATC V03AN01 VARIOUS
ALL OTHER THERAPEUTIC PRODUCTS
ALL OTHER THERAPEUTIC PRODUCTS
Medical gases
CHEBI has role CHEBI:27027 trace elements
CHEBI has role CHEBI:33284 nutrients
CHEBI has role CHEBI:33893 reagent
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:63248 oxidizing agent
CHEBI has role CHEBI:75772 baker's yeast metabolite
CHEBI has role CHEBI:77746 h. sapiens metabolites
CHEBI has role CHEBI:77974 food packaging gases
CHEBI has role CHEBI:33937 macronutrients

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4019105 VUID
N0000147362 NUI
D00003 KEGG_DRUG
4019105 VANDF
C0302920 UMLSCUI
CHEBI:15379 CHEBI
OXY PDB_CHEM_ID
CHEMBL1234886 ChEMBL_ID
D010100 MESH_DESCRIPTOR_UI
DB09140 DRUGBANK_ID
S88TT14065 UNII
977 PUBCHEM_CID
7806 RXNORM
d06860 MMSL
000826 NDDF
24099007 SNOMEDCT_US
767111007 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
OXYGEN HUMAN PRESCRIPTION DRUG LABEL 1 10006-001 GAS 99 L RESPIRATORY (INHALATION) unapproved medical gas 1 sections
MEDICAL AIR HUMAN PRESCRIPTION DRUG LABEL 1 10006-004 GAS 21 L RESPIRATORY (INHALATION) unapproved medical gas 1 sections
HELIOX HUMAN PRESCRIPTION DRUG LABEL 1 10006-009 GAS 20 L RESPIRATORY (INHALATION) unapproved medical gas 1 sections
HELIOX HUMAN PRESCRIPTION DRUG LABEL 1 10006-010 GAS 25 L RESPIRATORY (INHALATION) unapproved medical gas 1 sections
HELIOX HUMAN PRESCRIPTION DRUG LABEL 1 10006-011 GAS 30 L RESPIRATORY (INHALATION) unapproved medical gas 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10014-001 GAS 990 mL RESPIRATORY (INHALATION) NDA 1 sections
Oxygen Helium Mixture HUMAN PRESCRIPTION DRUG LABEL 2 10014-006 GAS 200 mL RESPIRATORY (INHALATION) unapproved medical gas 1 sections
Oxygen Helium Mixture 40/60 HUMAN PRESCRIPTION DRUG LABEL 2 10014-007 GAS 400 mL RESPIRATORY (INHALATION) unapproved medical gas 1 sections
Oxygen Helium Mixture 40/60 HUMAN PRESCRIPTION DRUG LABEL 1 10014-008 GAS 400 mL RESPIRATORY (INHALATION) NDA 1 sections
Oxygen Helium Mixture HUMAN PRESCRIPTION DRUG LABEL 1 10014-009 GAS 200 mL RESPIRATORY (INHALATION) NDA 1 sections
Oxygen Helium Mixture 30/70 HUMAN PRESCRIPTION DRUG LABEL 1 10014-018 GAS 300 mL RESPIRATORY (INHALATION) NDA 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10018-8999 GAS 990 mL RESPIRATORY (INHALATION) NDA 1 sections
oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10073-111 GAS 992 mL RESPIRATORY (INHALATION) NDA 1 sections
OXYGEN HUMAN PRESCRIPTION DRUG LABEL 1 10109-1234 GAS 99 L RESPIRATORY (INHALATION) unapproved medical gas 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10163-0202 GAS 99 L RESPIRATORY (INHALATION) unapproved medical gas 1 sections
OXYGEN HUMAN PRESCRIPTION DRUG LABEL 1 10167-100 GAS 99 L RESPIRATORY (INHALATION) NDA 1 sections
AIR COMPRESSED HUMAN PRESCRIPTION DRUG LABEL 1 10167-600 GAS 20 L RESPIRATORY (INHALATION) NDA 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10189-001 GAS 990 mL RESPIRATORY (INHALATION) NDA 1 sections
OXYGEN HUMAN PRESCRIPTION DRUG LABEL 1 10218-001 GAS 995 mL RESPIRATORY (INHALATION) NDA 1 sections
OXYGEN HUMAN PRESCRIPTION DRUG LABEL 1 10221-001 GAS 992 mL RESPIRATORY (INHALATION) NDA 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10252-001 GAS 990 mL RESPIRATORY (INHALATION) NDA 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10297-001 GAS 990 mL RESPIRATORY (INHALATION) NDA 1 sections
Air HUMAN PRESCRIPTION DRUG LABEL 1 10297-005 GAS 210 mL RESPIRATORY (INHALATION) NDA 1 sections
Heliox HUMAN PRESCRIPTION DRUG LABEL 1 10297-007 GAS 200 mL RESPIRATORY (INHALATION) NDA 1 sections
Heliox HUMAN PRESCRIPTION DRUG LABEL 1 10297-008 GAS 300 mL RESPIRATORY (INHALATION) NDA 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10304-463 GAS 995 mL RESPIRATORY (INHALATION) NDA 1 sections
OXYGEN HUMAN PRESCRIPTION DRUG LABEL 1 10358-1417 GAS 995 mL NULLSAL unapproved medical gas 1 sections
OXYGEN HUMAN PRESCRIPTION DRUG LABEL 1 10412-0001 GAS 99 L RESPIRATORY (INHALATION) NDA 1 sections
Oxygen HUMAN PRESCRIPTION DRUG LABEL 1 10451-001 GAS 992 mL RESPIRATORY (INHALATION) NDA 1 sections
Air HUMAN PRESCRIPTION DRUG LABEL 1 10451-004 GAS 210 mL RESPIRATORY (INHALATION) NDA 1 sections