All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

oxygen 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	4235	7782-44-7

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: oxygen molecular oxygen oxygen molecule oxygen, usp	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. Molecular weight: 32.00 Formula: O2 CLOGP: LIPINSKI: None HAC: 2 HDO: 0 TPSA: 34.14 ALOGS: ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Dyspnoea	933.44	11.56	1976	58270	659337	62769439
Pulmonary arterial hypertension	715.14	11.56	373	59873	22204	63406572
Oxygen saturation decreased	608.99	11.56	571	59675	88014	63340762
Pulmonary hypertension	533.93	11.56	369	59877	36754	63392022
Oxygen consumption increased	477.59	11.56	168	60078	3716	63425060
Right ventricular failure	457.40	11.56	253	59993	16935	63411841
Dyspnoea exertional	401.32	11.56	382	59864	59920	63368856
Fluid retention	376.25	11.56	367	59879	59319	63369457
Drug ineffective	365.49	11.56	277	59969	1044488	62384288
Chronic obstructive pulmonary disease	305.87	11.56	336	59910	62350	63366426
Respiratory failure	301.95	11.56	425	59821	101433	63327343
Hypoxia	297.84	11.56	324	59922	59468	63369308
Pneumonia	227.99	11.56	946	59300	455821	62972955
Hypervolaemia	221.99	11.56	197	60049	28216	63400560
Oxygen therapy	218.27	11.56	81	60165	2097	63426679
Transfusion	201.76	11.56	144	60102	15073	63413703
Contraindicated product administered	191.18	11.56	3	60243	217645	63211131
Pain in jaw	179.71	11.56	214	60032	43282	63385494
Acute respiratory failure	163.21	11.56	182	60064	34303	63394473
Nasal congestion	162.74	11.56	252	59994	65408	63363368
Oedema peripheral	160.14	11.56	468	59778	189043	63239733
Arthropathy	157.37	11.56	19	60227	234773	63194003
Treatment failure	155.86	11.56	8	60238	199035	63229741
Cough	150.92	11.56	613	59633	292130	63136646
Alopecia	150.58	11.56	66	60180	337470	63091306
Cardiac failure	143.68	11.56	283	59963	88859	63339917
Productive cough	140.71	11.56	231	60015	62977	63365799
Rheumatoid arthritis	140.64	11.56	34	60212	253785	63174991
Glossodynia	140.64	11.56	7	60239	178869	63249907
Drug intolerance	139.82	11.56	59	60187	308602	63120174
Therapeutic product effect decreased	136.16	11.56	13	60233	193174	63235602
Hand deformity	129.44	11.56	5	60241	159452	63269324
Joint swelling	125.52	11.56	78	60168	327588	63101188
Systemic lupus erythematosus	121.73	11.56	25	60221	208893	63219883
Pulmonary oedema	121.40	11.56	200	60046	54673	63374103
Rash	120.47	11.56	218	60028	560653	62868123
Pulmonary arterial pressure increased	118.35	11.56	61	60185	3534	63425242
Chest pain	114.98	11.56	457	59789	215502	63213274
Concomitant disease aggravated	106.68	11.56	80	60166	9032	63419744
Toxicity to various agents	106.07	11.56	51	60195	247199	63181577
Drug hypersensitivity	102.00	11.56	87	60159	310600	63118176
Epistaxis	100.80	11.56	217	60029	72508	63356268
Haemoptysis	98.87	11.56	129	60117	28597	63400179
Catheter site erythema	97.70	11.56	57	60189	4219	63424557
Oedema	97.08	11.56	256	59990	97366	63331410
Lung transplant	94.19	11.56	50	60196	3078	63425698
Catheter site pruritus	93.78	11.56	44	60202	2076	63426700
Musculoskeletal stiffness	90.67	11.56	31	60215	184587	63244189
Discomfort	89.62	11.56	24	60222	167350	63261426
Hepatic enzyme increased	87.88	11.56	41	60205	202287	63226489
Hypercapnia	87.58	11.56	58	60188	5373	63423403
Blood pressure decreased	85.54	11.56	190	60056	64832	63363944
Syncope	85.14	11.56	275	59971	117110	63311666
Pericarditis	80.33	11.56	14	60232	131565	63297211
Wound	79.16	11.56	28	60218	163235	63265541
Cardiac failure congestive	77.68	11.56	228	60018	92205	63336571
Dependence on oxygen therapy	77.07	11.56	25	60221	427	63428349
Catheter management	76.78	11.56	43	60203	2944	63425832
Off label use	75.87	11.56	356	59890	674106	62754670
Brain natriuretic peptide increased	75.30	11.56	52	60194	5161	63423615
Arthralgia	74.34	11.56	284	59962	569426	62859350
Psoriatic arthropathy	73.81	11.56	3	60243	91517	63337259
Scleroderma	73.11	11.56	52	60194	5410	63423366
Hypersensitivity	72.82	11.56	103	60143	292582	63136194
Headache	71.06	11.56	914	59332	632327	62796449
Hypotension	67.92	11.56	467	59779	272137	63156639
Infusion related reaction	67.66	11.56	80	60166	245441	63183335
Stomatitis	66.89	11.56	24	60222	138701	63290075
Death	66.55	11.56	593	59653	373788	63054988
Catheterisation cardiac	62.02	11.56	44	60202	4559	63424217
Product use issue	61.67	11.56	71	60175	220449	63208327
Pleural effusion	60.16	11.56	210	60036	93000	63335776
Cor pulmonale	59.51	11.56	32	60214	2022	63426754
Device alarm issue	59.30	11.56	29	60217	1501	63427275
Palpitations	58.60	11.56	237	60009	112533	63316243
Neutropenia	56.16	11.56	50	60196	174955	63253821
Pain	55.92	11.56	443	59803	740185	62688591
Pulmonary veno-occlusive disease	55.00	11.56	25	60221	1096	63427680
Therapeutic product effect incomplete	54.81	11.56	25	60221	125031	63303745
Maternal exposure during pregnancy	54.15	11.56	78	60168	219984	63208792
Pericardial effusion	54.01	11.56	100	60146	29958	63398818
Blister	53.78	11.56	28	60218	129786	63298990
Flushing	53.59	11.56	175	60071	74912	63353864
Cyanosis	53.58	11.56	73	60173	16862	63411914
Drug abuse	53.47	11.56	4	60242	72514	63356262
Catheter site pain	51.96	11.56	40	60206	4695	63424081
Device related infection	51.36	11.56	85	60161	23307	63405469
Unevaluable event	51.30	11.56	135	60111	51251	63377525
Dizziness	51.26	11.56	628	59618	429297	62999479
Air embolism	50.70	11.56	16	60230	249	63428527
Impaired healing	50.70	11.56	17	60229	102525	63326251
Chest discomfort	50.06	11.56	222	60024	109747	63319029
Blood cholesterol increased	49.35	11.56	14	60232	94018	63334758
Pruritus	49.13	11.56	177	60069	361276	63067500
Respiratory distress	48.97	11.56	103	60143	33848	63394928
Catheter site infection	48.51	11.56	39	60207	4875	63423901
Malaise	48.03	11.56	604	59642	415350	63013426
Irritable bowel syndrome	47.67	11.56	10	60236	82402	63346374
Thermal burn	47.36	11.56	42	60204	6004	63422772
Bronchitis	46.54	11.56	238	60008	124697	63304079
Catheter site discharge	46.43	11.56	27	60219	1986	63426790
Orthopnoea	46.09	11.56	42	60204	6219	63422557
Dyspnoea at rest	45.95	11.56	35	60211	4044	63424732
Exercise tolerance decreased	44.69	11.56	39	60207	5458	63423318
Catheter site rash	43.57	11.56	19	60227	754	63428022
Exposure during pregnancy	43.56	11.56	50	60196	155497	63273279
Intentional overdose	42.89	11.56	9	60237	74143	63354633
Infusion site pain	42.11	11.56	65	60181	16804	63411972
Chronic respiratory failure	41.98	11.56	25	60221	1922	63426854
Left ventricular failure	41.58	11.56	38	60208	5649	63423127
Respiratory tract infection	41.42	11.56	109	60137	41374	63387402
Transplant evaluation	41.40	11.56	21	60225	1176	63427600
Hospitalisation	41.19	11.56	175	60071	84906	63343870
Injection site erythema	40.75	11.56	14	60232	83160	63345616
Suicide attempt	40.59	11.56	5	60241	60913	63367863
Oxygen saturation abnormal	39.13	11.56	30	60216	3499	63425277
Atrial flutter	38.57	11.56	47	60199	9725	63419051
Mobility decreased	38.40	11.56	35	60211	121124	63307652
Intentional product use issue	38.14	11.56	39	60207	127853	63300923
Urticaria	37.67	11.56	62	60184	165740	63263036
Swelling	37.29	11.56	135	60111	275243	63153533
Injection site pain	37.13	11.56	41	60205	129759	63299017
Pulmonary arterial pressure abnormal	36.63	11.56	15	60231	508	63428268
Lung disorder	36.52	11.56	136	60110	62125	63366651
Pulmonary congestion	36.51	11.56	62	60184	17356	63411420
Liver injury	35.72	11.56	7	60239	60513	63368263
Psoriasis	35.65	11.56	19	60227	86938	63341838
Subcutaneous emphysema	35.33	11.56	17	60229	849	63427927
Nasal dryness	34.25	11.56	31	60215	4550	63424226
Cardiac disorder	34.08	11.56	116	60130	50700	63378076
Presyncope	34.08	11.56	79	60167	27706	63401070
Interstitial lung disease	33.66	11.56	132	60114	61776	63367000
Abdominal distension	33.65	11.56	167	60079	86448	63342328
Cardiac arrest	33.55	11.56	175	60071	92370	63336406
Atrial fibrillation	33.36	11.56	207	60039	116429	63312347
Emphysema	32.88	11.56	46	60200	10892	63417884
Aspiration pleural cavity	32.31	11.56	16	60230	851	63427925
Abdominal discomfort	32.15	11.56	176	60070	320709	63108067
Bladder agenesis	32.09	11.56	10	60236	149	63428627
Injection site reaction	32.05	11.56	8	60238	58516	63370260
Ill-defined disorder	31.88	11.56	19	60227	81736	63347040
Ascites	31.86	11.56	98	60148	40630	63388146
Oxygen consumption	31.80	11.56	9	60237	94	63428682
Cloacal exstrophy	31.67	11.56	10	60236	156	63428620
Genitalia external ambiguous	31.67	11.56	10	60236	156	63428620
Pulmonary hypertensive crisis	31.58	11.56	12	60234	332	63428444
Cardiac failure acute	31.57	11.56	42	60204	9481	63419295
Congenital ectopic bladder	31.46	11.56	9	60237	98	63428678
Catheter placement	31.16	11.56	22	60224	2262	63426514
Overdose	31.13	11.56	38	60208	115040	63313736
Febrile neutropenia	31.12	11.56	40	60206	118409	63310367
Central venous catheterisation	30.82	11.56	23	60223	2576	63426200
Oedematous kidney	30.44	11.56	9	60237	111	63428665
Anaemia	30.02	11.56	417	59829	293013	63135763
Device occlusion	29.92	11.56	36	60210	7351	63421425
Meconium stain	29.79	11.56	10	60236	191	63428585
Device leakage	29.43	11.56	35	60211	7061	63421715
Cardiac pacemaker insertion	29.06	11.56	27	60219	4099	63424677
Gastrointestinal disorder congenital	28.83	11.56	9	60237	135	63428641
Knee arthroplasty	28.57	11.56	8	60238	54198	63374578
Product use in unapproved indication	28.25	11.56	82	60164	178998	63249778
Congenital genital malformation	28.12	11.56	9	60237	147	63428629
Paracentesis	27.79	11.56	15	60231	955	63427821
Rales	27.69	11.56	46	60200	12651	63416125
Sputum discoloured	27.64	11.56	53	60193	16294	63412482
Lipodystrophy acquired	27.10	11.56	17	60229	1435	63427341
Caudal regression syndrome	27	11.56	9	60237	168	63428608
Fibromyalgia	26.97	11.56	22	60224	80398	63348378
Heart rate increased	26.78	11.56	167	60079	94071	63334705
Cardiac ablation	26.75	11.56	17	60229	1468	63427308
Gamma-glutamyltransferase increased	26.73	11.56	82	60164	33949	63394827
Pneumothorax	26.62	11.56	52	60194	16209	63412567
Gastrointestinal malformation	26.47	11.56	9	60237	179	63428597
Tethered cord syndrome	26.41	11.56	10	60236	274	63428502
Pulmonary function test decreased	26.21	11.56	25	60221	3922	63424854
Red blood cell sedimentation rate increased	26.14	11.56	5	60241	43977	63384799
Lower respiratory tract infection	26.03	11.56	54	60192	132253	63296523
Product dose omission issue	26.02	11.56	338	59908	233975	63194801
Walking distance test abnormal	25.66	11.56	12	60234	562	63428214
N-terminal prohormone brain natriuretic peptide increased	25.35	11.56	19	60227	2142	63426634
Adverse drug reaction	25.28	11.56	23	60223	79691	63349085
Osteoarthritis	25.24	11.56	32	60214	95311	63333465
Catheter site scab	25.20	11.56	9	60237	208	63428568
Anaesthetic complication	24.72	11.56	18	60228	1942	63426834
Cognitive disorder	24.69	11.56	11	60235	55804	63372972
Catheter site swelling	24.29	11.56	16	60230	1469	63427307
Congestive hepatopathy	24.17	11.56	21	60225	2921	63425855
Confusional state	24.02	11.56	129	60117	236251	63192525
Haemoglobin decreased	24.01	11.56	227	60019	145258	63283518
Infusion site erythema	23.73	11.56	41	60205	11638	63417138
Injury	23.39	11.56	21	60225	73226	63355550
Pancreatitis haemorrhagic	23.38	11.56	11	60235	522	63428254
Carbon dioxide increased	23.19	11.56	15	60231	1335	63427441
Anal atresia	23.14	11.56	10	60236	388	63428388
C-reactive protein increased	22.85	11.56	34	60212	94673	63334103
Oedematous pancreatitis	22.48	11.56	11	60235	570	63428206
Upper respiratory tract infection	22.45	11.56	144	60102	81903	63346873
Neuromuscular blockade	22.43	11.56	9	60237	289	63428487
Gout	22.41	11.56	43	60203	13228	63415548
Pneumomediastinum	22.34	11.56	15	60231	1421	63427355
Haematocrit decreased	22.29	11.56	85	60161	39255	63389521
Accident	22.18	11.56	28	60218	6004	63422772
Anencephaly	22.17	11.56	9	60237	298	63428478
Neural tube defect	22.04	11.56	8	60238	194	63428582
Condition aggravated	22.03	11.56	518	59728	401699	63027077
Nocturnal dyspnoea	22.01	11.56	14	60232	1210	63427566
Type 2 diabetes mellitus	22.01	11.56	17	60229	63851	63364925
Pulmonary trichosporonosis	21.81	11.56	6	60240	56	63428720
Depression	21.80	11.56	104	60142	196388	63232388
Blood iron decreased	21.62	11.56	45	60201	14676	63414100
Iron deficiency anaemia	21.51	11.56	54	60192	19915	63408861
Injection site pruritus	21.40	11.56	8	60238	45108	63383668
Concomitant disease progression	21.20	11.56	17	60229	2117	63426659
Paraesthesia	21.19	11.56	77	60169	156889	63271887
Rhinorrhoea	21.06	11.56	120	60126	65457	63363319
Suicidal ideation	21.03	11.56	17	60229	62404	63366372
Device connection issue	20.92	11.56	11	60235	664	63428112
Gastrointestinal disorder	20.76	11.56	60	60186	131179	63297597
Upper respiratory tract inflammation	20.71	11.56	18	60228	2505	63426271
Cardiomegaly	20.43	11.56	49	60197	17565	63411211
Bursitis	20.41	11.56	5	60241	37036	63391740
Leukopenia	20.40	11.56	26	60220	77264	63351512
Injection site swelling	20.08	11.56	10	60236	47562	63381214
Tachypnoea	19.92	11.56	48	60198	17254	63411522
Localised oedema	19.83	11.56	25	60221	5353	63423423
Stent placement	19.82	11.56	21	60225	3734	63425042
Disease progression	19.49	11.56	190	60056	122568	63306208
Paradoxical embolism	19.44	11.56	5	60241	35	63428741
Infusion site infection	19.34	11.56	15	60231	1779	63426997
Sepsis	19.19	11.56	226	60020	152897	63275879
Aspartate aminotransferase increased	19.17	11.56	149	60097	90128	63338648
Right ventricular dysfunction	19.16	11.56	15	60231	1804	63426972
Supraventricular tachycardia	19.09	11.56	42	60204	14229	63414547
Meningomyelocele	18.95	11.56	10	60236	608	63428168
Pulmonary artery banding	18.84	11.56	4	60242	10	63428766
Hip arthroplasty	18.67	11.56	11	60235	47635	63381141
Frostbite	18.52	11.56	6	60240	102	63428674
Hepatic function abnormal	18.43	11.56	77	60169	37065	63391711
Sepsis neonatal	18.38	11.56	9	60237	467	63428309
Umbilical cord abnormality	18.29	11.56	10	60236	653	63428123
Hyperandrogenism	18.26	11.56	6	60240	107	63428669
Uterine hypotonus	18.20	11.56	6	60240	108	63428668
Feeling abnormal	18.14	11.56	218	60028	148174	63280602
Lung assist device therapy	18	11.56	6	60240	112	63428664
Multiple sclerosis relapse	17.89	11.56	12	60234	48466	63380310
Pulmonary alveolar haemorrhage	17.69	11.56	22	60224	4646	63424130
Malignant neoplasm progression	17.46	11.56	32	60214	82089	63346687
Mediastinal effusion	17.27	11.56	5	60241	57	63428719
Right ventricular systolic pressure increased	17.20	11.56	9	60237	538	63428238
Oxygen consumption decreased	17.15	11.56	7	60239	235	63428541
PO2 decreased	17.13	11.56	13	60233	1493	63427283
Osteonecrosis of jaw	17.05	11.56	6	60240	35117	63393659
Exomphalos	17.04	11.56	9	60237	548	63428228
Pulmonary haemorrhage	16.99	11.56	27	60219	7154	63421622
Cardioversion	16.87	11.56	12	60234	1248	63427528
Bronchospasm	16.83	11.56	45	60201	17235	63411541
Argon plasma coagulation	16.53	11.56	4	60242	21	63428755
Accidental underdose	16.51	11.56	10	60236	793	63427983
Platelet transfusion	16.47	11.56	10	60236	796	63427980
Abdominal cavity drainage	16.45	11.56	8	60238	409	63428367
Neoplasm progression	16.40	11.56	7	60239	36421	63392355
Enlarged clitoris	16.29	11.56	6	60240	152	63428624
Angioedema	16.23	11.56	13	60233	47952	63380824
Terminal state	16.20	11.56	15	60231	2267	63426509
Compartment syndrome	16.19	11.56	15	60231	2269	63426507
Rehabilitation therapy	16.08	11.56	13	60233	1637	63427139
Tachycardia	15.97	11.56	177	60069	117979	63310797
Pulmonary artery dilatation	15.95	11.56	7	60239	282	63428494
Neuropathy peripheral	15.84	11.56	55	60191	113612	63315164
Inflammation	15.82	11.56	34	60212	82239	63346537
Acute postoperative sialadenitis	15.81	11.56	4	60242	26	63428750
Cold burn	15.81	11.56	3	60243	3	63428773
Idiopathic pulmonary fibrosis	15.80	11.56	12	60234	1380	63427396
Pulmonary pain	15.79	11.56	18	60228	3472	63425304
Catheter site inflammation	15.78	11.56	10	60236	859	63427917
Echocardiogram	15.68	11.56	4	60242	27	63428749
Coma	15.63	11.56	23	60223	64341	63364435
Rhinocerebral mucormycosis	15.62	11.56	8	60238	457	63428319
Deafness bilateral	15.43	11.56	12	60234	1430	63427346
Oral herpes	15.42	11.56	3	60243	26071	63402705
Head injury	15.36	11.56	59	60187	27337	63401439
Pulmonary capillary haemangiomatosis	15.31	11.56	4	60242	30	63428746
Barotrauma	15.27	11.56	6	60240	182	63428594
Tracheostomy	15.24	11.56	9	60237	681	63428095
Procedural hypotension	15.17	11.56	11	60235	1179	63427597
Pneumonia bacterial	15.17	11.56	30	60216	9435	63419341
Middle ear effusion	15.08	11.56	15	60231	2476	63426300
Live birth	15.05	11.56	3	60243	25627	63403149
Blood urea increased	14.95	11.56	57	60189	26322	63402454
Foot deformity	14.88	11.56	4	60242	27849	63400927
Neutrophil count decreased	14.86	11.56	19	60227	56387	63372389
Prescribed overdose	14.69	11.56	7	60239	34146	63394630
Systemic scleroderma	14.67	11.56	10	60236	971	63427805
Rhonchi	14.66	11.56	15	60231	2561	63426215
Injection site bruising	14.64	11.56	11	60235	41899	63386877
Jugular vein distension	14.63	11.56	10	60236	976	63427800
Therapy change	14.58	11.56	23	60223	6058	63422718
Hepatitis	14.48	11.56	10	60236	39778	63388998
Limb injury	14.39	11.56	55	60191	25422	63403354
Catheter site warmth	14.33	11.56	6	60240	215	63428561
Hypertension	14.31	11.56	183	60063	279120	63149656
Bone marrow failure	14.22	11.56	5	60241	29285	63399491
Catheter site hypersensitivity	14.15	11.56	5	60241	112	63428664
Hypoglycaemia	14.06	11.56	22	60224	60043	63368733
Dizziness exertional	13.95	11.56	7	60239	383	63428393
Decreased activity	13.92	11.56	23	60223	6297	63422479
Choking sensation	13.87	11.56	17	60229	3537	63425239
COVID-19 pneumonia	13.84	11.56	37	60209	14172	63414604
Gastrointestinal arteriovenous malformation	13.81	11.56	8	60238	584	63428192
Biopsy liver	13.77	11.56	7	60239	394	63428382
Hospice care	13.76	11.56	26	60220	7906	63420870
Pregnancy	13.75	11.56	9	60237	36827	63391949
Catheter site haemorrhage	13.73	11.56	16	60230	3159	63425617
Distributive shock	13.70	11.56	11	60235	1372	63427404
Chills	13.61	11.56	166	60080	113212	63315564
Colitis ulcerative	13.47	11.56	4	60242	26087	63402689
Red blood cell count decreased	13.46	11.56	75	60171	40570	63388206
Spina bifida	13.43	11.56	9	60237	850	63427926
Joint range of motion decreased	13.41	11.56	7	60239	32421	63396355
Urinary retention	13.36	11.56	6	60240	30295	63398481
Increased bronchial secretion	13.30	11.56	12	60234	1754	63427022
Pneumoperitoneum	13.29	11.56	11	60235	1432	63427344
Disease recurrence	13.25	11.56	5	60241	28025	63400751
Breath sounds abnormal	13.24	11.56	31	60215	10942	63417834
Mucosal inflammation	13.22	11.56	15	60231	46913	63381863
Secretion discharge	13.09	11.56	33	60213	12198	63416578
Cellulitis	13.07	11.56	127	60119	81831	63346945
Abdominal pain	13.00	11.56	198	60048	293258	63135518
Pneumonia mycoplasmal	12.83	11.56	9	60237	916	63427860
Sinus congestion	12.71	11.56	42	60204	18081	63410695
Hypozincaemia	12.69	11.56	3	60243	14	63428762
Mastitis bacterial	12.57	11.56	4	60242	64	63428712
Right ventricular hypertrophy	12.54	11.56	8	60238	695	63428081
Burns third degree	12.54	11.56	6	60240	296	63428480
Menstrual discomfort	12.52	11.56	3	60243	15	63428761
Vascular cauterisation	12.52	11.56	4	60242	65	63428711
Catheter site erosion	12.52	11.56	4	60242	65	63428711
Cardiac failure high output	12.48	11.56	6	60240	299	63428477
Lung squamous cell carcinoma stage I	12.36	11.56	3	60243	16	63428760
Respiration abnormal	12.35	11.56	22	60224	6395	63422381
Apnoea	12.34	11.56	25	60221	7997	63420779
Sinus disorder	12.26	11.56	51	60195	24502	63404274
Therapeutic response decreased	12.19	11.56	25	60221	61500	63367276
Decreased appetite	12.13	11.56	318	59928	250734	63178042
Ventilation perfusion mismatch	12.09	11.56	7	60239	511	63428265
Gastrointestinal haemorrhage	12.08	11.56	124	60122	81052	63347724
Dialysis	12.08	11.56	29	60217	10398	63418378
Cutaneous mucormycosis	12.06	11.56	3	60243	18	63428758
Administration site pruritus	12.05	11.56	6	60240	323	63428453
Right ventricular enlargement	12.05	11.56	6	60240	323	63428453
Acute right ventricular failure	12.00	11.56	5	60241	177	63428599
Oesophageal dilation procedure	11.93	11.56	4	60242	76	63428700
Premature baby	11.91	11.56	45	60201	20690	63408086
Diverticulitis	11.86	11.56	12	60234	39545	63389231
Device infusion issue	11.84	11.56	12	60234	2026	63426750
Glossoptosis	11.84	11.56	4	60242	78	63428698
Weight decreased	11.79	11.56	345	59901	276453	63152323
Neuromuscular block prolonged	11.79	11.56	7	60239	535	63428241
Brain hypoxia	11.74	11.56	7	60239	539	63428237
Stress cardiomyopathy	11.73	11.56	27	60219	9423	63419353
Right ventricular dilatation	11.67	11.56	10	60236	1366	63427410
Seasonal allergy	11.65	11.56	45	60201	20905	63407871
Blood potassium decreased	11.64	11.56	74	60172	41952	63386824
Emergency care	11.62	11.56	9	60237	1065	63427711

FDA Adverse Event Reporting System (Male)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Dyspnoea	362.12	12.42	917	29385	375865	34550764
Oxygen saturation decreased	344.09	12.42	320	29982	53498	34873131
Pulmonary arterial hypertension	311.77	12.42	152	30150	8587	34918042
Hypoxia	246.29	12.42	270	30032	54825	34871804
Right ventricular failure	205.02	12.42	115	30187	8669	34917960
Oxygen consumption increased	176.76	12.42	60	30242	1306	34925323
Pulmonary hypertension	166.55	12.42	141	30161	20783	34905846
Respiratory failure	152.04	12.42	308	29994	108264	34818365
Chronic obstructive pulmonary disease	139.23	12.42	191	30111	48727	34877902
Pneumonia	117.73	12.42	621	29681	362006	34564623
Thermal burn	114.91	12.42	53	30249	2638	34923991
Fluid retention	113.51	12.42	128	30174	26759	34899870
Concomitant disease aggravated	112.67	12.42	67	30235	5634	34920995
Acute respiratory failure	92.88	12.42	124	30178	30804	34895825
Dyspnoea exertional	84.71	12.42	142	30160	43137	34883492
Toxicity to various agents	72.35	12.42	42	30260	200320	34726309
Oxygen therapy	69.60	12.42	27	30275	869	34925760
Pain in jaw	67.18	12.42	69	30233	12971	34913658
Completed suicide	63.29	12.42	6	30296	98162	34828467
Transfusion	60.50	12.42	54	30248	8531	34918098
Hypervolaemia	57.59	12.42	78	30224	19631	34906998
Drug abuse	56.69	12.42	9	30293	99087	34827542
Pneumothorax	56.46	12.42	76	30226	19016	34907613
Nasal congestion	53.81	12.42	82	30220	22975	34903654
Accidental underdose	52.76	12.42	19	30283	495	34926134
Respiratory distress	51.96	12.42	103	30199	35562	34891067
Cerebral artery thrombosis	51.84	12.42	21	30281	759	34925870
Pulmonary oedema	51.75	12.42	122	30180	47407	34879222
Hypercapnia	49.73	12.42	36	30266	4219	34922410
Cough	49.66	12.42	259	30043	149881	34776748
Brain scan abnormal	49.39	12.42	21	30281	859	34925770
Pulmonary arterial pressure increased	45.08	12.42	22	30280	1243	34925386
Haemoptysis	39.35	12.42	91	30211	34915	34891714
Oedema	38.95	12.42	107	30195	45634	34880995
Drug ineffective	38.77	12.42	235	30067	456516	34470113
Neutropenia	38.07	12.42	48	30254	156730	34769899
Burns third degree	37.90	12.42	12	30290	208	34926421
Accident	36.06	12.42	32	30270	5015	34921614
Lung transplant	35.40	12.42	22	30280	2002	34924627
Cardiac arrest	35.36	12.42	171	30131	95988	34830641
Idiopathic pulmonary fibrosis	34.83	12.42	27	30275	3507	34923122
Brain natriuretic peptide increased	34.82	12.42	33	30269	5626	34921003
Blood pressure decreased	32.10	12.42	108	30194	51407	34875222
Catheter site erythema	31.73	12.42	18	30284	1385	34925244
Areflexia	31.72	12.42	24	30278	3007	34923622
Chronic respiratory failure	31.42	12.42	18	30284	1411	34925218
Cyanosis	30.63	12.42	46	30256	12718	34913911
COVID-19 pneumonia	29.67	12.42	53	30249	16914	34909715
Catheter management	29.14	12.42	15	30287	950	34925679
Catheter placement	28.80	12.42	14	30288	784	34925845
Cor pulmonale	28.50	12.42	14	30288	802	34925827
Emphysema	28.28	12.42	38	30264	9487	34917142
Cardiac failure	27.80	12.42	154	30148	91094	34835535
Condition aggravated	27.63	12.42	271	30031	191925	34734704
Lung disorder	26.45	12.42	78	30224	34618	34892011
Catheter site haemorrhage	26.41	12.42	19	30283	2205	34924424
Oedema peripheral	26.36	12.42	186	30116	119626	34807003
Mechanical ventilation	26.11	12.42	18	30284	1952	34924677
Catheter removal	26.00	12.42	9	30293	208	34926421
Air embolism	25.46	12.42	8	30294	135	34926494
Respiratory tract infection	25.25	12.42	54	30248	19658	34906971
Productive cough	25.10	12.42	81	30221	37732	34888897
Neuromuscular block prolonged	24.99	12.42	11	30291	490	34926139
Transplant evaluation	24.88	12.42	11	30291	495	34926134
Pulmonary function test abnormal	23.70	12.42	19	30283	2591	34924038
Rhinocerebral mucormycosis	23.67	12.42	11	30291	557	34926072
Intentional overdose	22.75	12.42	5	30297	43669	34882960
Catheter site pain	22.03	12.42	14	30288	1324	34925305
Interstitial lung disease	21.79	12.42	113	30189	65169	34861460
Hypotension	21.68	12.42	290	30012	221359	34705270
Catheterisation cardiac	21.20	12.42	18	30284	2659	34923970
Pulmonary veno-occlusive disease	21.18	12.42	10	30292	525	34926104
Subacute combined cord degeneration	20.94	12.42	7	30295	145	34926484
Pulmonary fibrosis	20.86	12.42	48	30254	18348	34908281
Rotavirus infection	20.55	12.42	9	30293	396	34926233
Barotrauma	20.02	12.42	5	30297	34	34926595
Ventilation perfusion mismatch	19.94	12.42	6	30296	87	34926542
Catheter site granuloma	19.77	12.42	5	30297	36	34926593
Respiratory acidosis	19.54	12.42	23	30279	5027	34921602
Carbon dioxide increased	19.54	12.42	12	30290	1069	34925560
Treatment failure	19.53	12.42	8	30294	46689	34879940
Catheter site discharge	19.43	12.42	10	30292	633	34925996
SARS-CoV-2 viraemia	19.42	12.42	5	30297	39	34926590
PaO2/FiO2 ratio decreased	19.42	12.42	5	30297	39	34926590
Headache	19.40	12.42	262	30040	200373	34726256
Anaesthetic complication	19.15	12.42	12	30290	1108	34925521
Abdominal pain	19.12	12.42	75	30227	163543	34763086
Burns second degree	19.06	12.42	12	30290	1117	34925512
Epistaxis	18.87	12.42	100	30202	58151	34868478
Tachypnoea	18.77	12.42	46	30256	18306	34908323
Catheter site pruritus	18.75	12.42	8	30294	330	34926299
Rheumatoid arthritis	18.70	12.42	5	30297	38233	34888396
Ventricular tachycardia	18.61	12.42	58	30244	26521	34900108
White blood cell count decreased	18.54	12.42	34	30268	95411	34831218
Subcutaneous emphysema	18.44	12.42	12	30290	1182	34925447
Pulmonary function test decreased	18.17	12.42	22	30280	4953	34921676
Catheter site warmth	18.05	12.42	5	30297	53	34926576
Hyperthermia malignant	17.99	12.42	15	30287	2162	34924467
Cardiac failure congestive	17.56	12.42	128	30174	83142	34843487
Aggression	17.42	12.42	6	30296	38958	34887671
Procedural complication	17.40	12.42	20	30282	4263	34922366
Drug interaction	17.17	12.42	120	30182	225826	34700803
Bradycardia	17.11	12.42	118	30184	75300	34851329
Pneumomediastinum	16.90	12.42	15	30287	2352	34924277
Confusional state	16.89	12.42	66	30236	144094	34782535
Pulmonary congestion	16.82	12.42	37	30265	13728	34912901
Thyroglobulin increased	16.74	12.42	4	30298	22	34926607
Frostbite	16.65	12.42	5	30297	72	34926557
Pulmonary alveolar haemorrhage	16.52	12.42	26	30276	7486	34919143
Hyponatraemia	16.47	12.42	29	30273	82662	34843967
Therapeutic product effect incomplete	16.29	12.42	12	30290	50529	34876100
Pulmonary hypertensive crisis	16.29	12.42	6	30296	167	34926462
Hypocapnia	16.22	12.42	6	30296	169	34926460
Thrombocytopenia	16.17	12.42	75	30227	156172	34770457
Apnoea	15.96	12.42	24	30278	6640	34919989
Walking distance test abnormal	15.96	12.42	6	30296	177	34926452
Anaesthetic complication cardiac	15.79	12.42	4	30298	29	34926600
Superinfection fungal	15.79	12.42	4	30298	29	34926600
Pulse pressure decreased	15.74	12.42	6	30296	184	34926445
Alkalosis hypochloraemic	15.63	12.42	7	30295	325	34926304
Leukopenia	15.49	12.42	19	30283	62837	34863792
Thoracic cavity drainage	15.41	12.42	6	30296	195	34926434
Complication associated with device	14.92	12.42	22	30280	5984	34920645
Infusion site vesicles	14.86	12.42	6	30296	215	34926414
Dependence on oxygen therapy	14.86	12.42	6	30296	215	34926414
Catheter site inflammation	14.73	12.42	6	30296	220	34926409
Pulseless electrical activity	14.54	12.42	24	30278	7187	34919442
Haemodynamic instability	14.46	12.42	28	30274	9495	34917134
Respiratory disorder	14.38	12.42	43	30259	19221	34907408
Bronchopulmonary aspergillosis	14.21	12.42	36	30266	14623	34912006
Aspartate aminotransferase increased	14.17	12.42	104	30198	67679	34858950
Acute kidney injury	14.16	12.42	183	30119	304805	34621824
Acute right ventricular failure	14.15	12.42	5	30297	123	34926506
Syncope	14.12	12.42	131	30171	91320	34835309
Pulmonary haemorrhage	14.09	12.42	29	30273	10275	34916354
Mucosal inflammation	14.04	12.42	8	30294	38614	34888015
Device intolerance	14.00	12.42	3	30299	9	34926620
Hemiplegia	13.79	12.42	23	30279	6949	34919680
Myotonic dystrophy	13.41	12.42	5	30297	144	34926485
Rash maculo-papular	13.39	12.42	4	30298	28447	34898182
Coma	13.28	12.42	12	30290	45666	34880963
Myocardial infarction	13.20	12.42	57	30245	121028	34805601
Suicide attempt	12.98	12.42	9	30293	39107	34887522
Therapeutic product effect decreased	12.91	12.42	7	30295	34736	34891893
Febrile neutropenia	12.83	12.42	68	30234	136781	34789848
Electrocardiogram ST segment elevation	12.74	12.42	19	30283	5219	34921410
Dyspnoea at rest	12.49	12.42	16	30286	3812	34922817
Cardiac failure acute	12.45	12.42	28	30274	10542	34916087
Thoracotomy	12.44	12.42	4	30298	73	34926556
Device related infection	12.42	12.42	38	30264	17199	34909430

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Dyspnoea	1034.98	10.86	2458	75855	854567	78811508
Pulmonary arterial hypertension	941.34	10.86	489	77824	27877	79638198
Oxygen saturation decreased	794.44	10.86	795	77518	128252	79537823
Pulmonary hypertension	606.01	10.86	447	77866	47633	79618442
Oxygen consumption increased	588.52	10.86	211	78102	4768	79661307
Right ventricular failure	568.93	10.86	329	77984	23168	79642907
Fluid retention	469.98	10.86	452	77861	69357	79596718
Hypoxia	459.13	10.86	536	77777	102707	79563368
Dyspnoea exertional	412.27	10.86	467	77846	86606	79579469
Respiratory failure	313.93	10.86	604	77709	180307	79485768
Chronic obstructive pulmonary disease	312.47	10.86	402	77911	85017	79581058
Hypervolaemia	256.68	10.86	260	78053	42430	79623645
Drug ineffective	250.10	10.86	425	77888	1080488	78585587
Pain in jaw	248.60	10.86	265	78048	45886	79620189
Pneumonia	244.97	10.86	1285	77028	658961	79007114
Transfusion	239.12	10.86	185	78128	21145	79644930
Oxygen therapy	220.09	10.86	88	78225	2702	79663373
Completed suicide	213.54	10.86	6	78307	245761	79420314
Acute respiratory failure	212.64	10.86	277	78036	59264	79606811
Toxicity to various agents	198.30	10.86	83	78230	421457	79244618
Concomitant disease aggravated	187.68	10.86	132	78181	13035	79653040
Nasal congestion	186.53	10.86	297	78016	76255	79589820
Oedema peripheral	162.65	10.86	581	77732	251707	79414368
Cough	148.87	10.86	733	77580	366056	79300019
Pulmonary oedema	145.98	10.86	289	78024	87965	79578110
Pulmonary arterial pressure increased	132.56	10.86	72	78241	4483	79661592
Catheter site erythema	128.45	10.86	74	78239	5166	79660909
Oedema	126.62	10.86	328	77985	119252	79546823
Contraindicated product administered	123.15	10.86	8	78305	157530	79508545
Drug abuse	119.48	10.86	11	78302	162680	79503395
Therapeutic product effect decreased	117.91	10.86	12	78301	163851	79502224
Cardiac failure	115.87	10.86	375	77938	154467	79511608
Rheumatoid arthritis	115.40	10.86	31	78282	208439	79457636
Treatment failure	114.01	10.86	16	78297	170470	79495605
Hypercapnia	112.31	10.86	83	78230	8852	79657223
Lung transplant	110.71	10.86	64	78249	4497	79661578
Catheter site pruritus	110.43	10.86	51	78262	2240	79663835
Productive cough	110.15	10.86	258	78055	88073	79578002
Arthropathy	108.68	10.86	21	78292	177090	79488985
Brain natriuretic peptide increased	108.12	10.86	81	78232	8819	79657256
Thermal burn	107.23	10.86	74	78239	7086	79658989
Haemoptysis	103.17	10.86	192	78121	55807	79610268
Chest pain	99.72	10.86	543	77770	281761	79384314
Neutropenia	99.36	10.86	82	78231	287628	79378447
Blood pressure decreased	98.34	10.86	266	78047	99200	79566875
Drug intolerance	97.92	10.86	70	78243	264049	79402026
Alopecia	92.96	10.86	56	78257	231299	79434776
Headache	90.96	10.86	1011	77302	652761	79013314
Catheter management	87.85	10.86	51	78262	3612	79662463
Epistaxis	86.05	10.86	273	78040	111242	79554833
Catheterisation cardiac	82.97	10.86	58	78255	5670	79660405
Respiratory distress	81.17	10.86	178	78135	58161	79607914
Rash	80.86	10.86	294	78019	578064	79088011
Joint swelling	79.49	10.86	100	78213	288546	79377529
Hand deformity	79.11	10.86	6	78307	103913	79562162
Cyanosis	77.46	10.86	109	78204	25073	79641002
Drug hypersensitivity	76.78	10.86	109	78204	298807	79367268
Syncope	75.76	10.86	363	77950	179086	79486989
Air embolism	72.48	10.86	24	78289	423	79665652
Scleroderma	71.09	10.86	52	78261	5458	79660617
Catheter site pain	69.79	10.86	51	78262	5345	79660730
Intentional overdose	68.40	10.86	11	78302	105949	79560126
Glossodynia	68.36	10.86	10	78303	103327	79562748
Pulmonary veno-occlusive disease	68.12	10.86	33	78280	1615	79664460
Musculoskeletal stiffness	68.02	10.86	44	78269	174964	79491111
Stomatitis	67.12	10.86	30	78283	146727	79519348
Dependence on oxygen therapy	67.09	10.86	24	78289	538	79665537
Pericarditis	66.88	10.86	11	78302	104225	79561850
Hypotension	66.23	10.86	692	77621	439625	79226450
Hepatic enzyme increased	63.06	10.86	52	78261	182558	79483517
Catheter site discharge	61.63	10.86	35	78278	2377	79663698
Device alarm issue	60.73	10.86	33	78280	2056	79664019
Accidental underdose	60.49	10.86	25	78288	837	79665238
Unevaluable event	60.37	10.86	154	78159	55431	79610644
Cardiac failure congestive	60.04	10.86	288	78025	142114	79523961
Pneumothorax	59.70	10.86	103	78210	28220	79637855
Chronic respiratory failure	59.33	10.86	37	78276	2985	79663090
Device related infection	57.51	10.86	113	78200	34181	79631894
Flushing	57.37	10.86	204	78109	88064	79578011
Therapeutic product effect incomplete	57.27	10.86	34	78279	141611	79524464
Systemic lupus erythematosus	56.61	10.86	24	78289	121125	79544950
Arthralgia	55.93	10.86	331	77982	571472	79094603
Catheter site infection	55.38	10.86	49	78264	6746	79659329
Pleural effusion	55.02	10.86	285	78028	144977	79521098
Catheter placement	54.85	10.86	35	78278	2939	79663136
Pulmonary hypertensive crisis	53.10	10.86	18	78295	342	79665733
Transplant evaluation	52.67	10.86	28	78285	1669	79664406
Hypersensitivity	52.41	10.86	112	78201	262127	79403948
Emphysema	52.29	10.86	72	78241	16228	79649847
Pericardial effusion	51.15	10.86	129	78184	46108	79619967
Catheter site rash	50.41	10.86	23	78290	982	79665093
Infusion related reaction	49.71	10.86	94	78219	230143	79435932
Intentional product use issue	49.27	10.86	46	78267	152066	79514009
Off label use	49.23	10.86	613	77700	906602	78759473
Palpitations	49.05	10.86	250	78063	126360	79539715
Cor pulmonale	47.66	10.86	29	78284	2239	79663836
Cardiac arrest	46.58	10.86	309	78004	171787	79494288
Condition aggravated	46.05	10.86	719	77594	500405	79165670
Confusional state	44.77	10.86	161	78152	317836	79348239
Overdose	44.52	10.86	70	78243	184136	79481939
Discomfort	44.32	10.86	35	78278	125582	79540493
Dizziness	44.15	10.86	744	77569	525697	79140378
Pulmonary congestion	43.88	10.86	88	78225	27012	79639063
Blood cholesterol increased	43.46	10.86	14	78299	83706	79582369
Helicobacter infection	43.30	10.86	8	78305	69696	79596379
Infusion site pain	43.06	10.86	61	78252	14115	79651960
Dyspnoea at rest	43.00	10.86	44	78269	7258	79658817
Suicide attempt	42.82	10.86	14	78299	82918	79583157
Febrile neutropenia	42.63	10.86	103	78210	230896	79435179
Lung disorder	40.75	10.86	172	78141	80385	79585690
Mobility decreased	40.69	10.86	36	78277	122139	79543936
Subcutaneous emphysema	40.45	10.86	24	78289	1770	79664305
Brain scan abnormal	40.29	10.86	21	78292	1202	79664873
Respiratory tract infection	40.13	10.86	122	78191	48567	79617508
Injection site pain	40.04	10.86	41	78272	129797	79536278
Pulmonary function test decreased	39.60	10.86	43	78270	7594	79658481
Orthopnoea	39.31	10.86	49	78264	10024	79656051
Cerebral artery thrombosis	39.27	10.86	20	78293	1091	79664984
Anaesthetic complication	39.21	10.86	28	78285	2831	79663244
Cardiac failure acute	38.80	10.86	68	78245	18861	79647214
Pruritus	38.77	10.86	228	78085	394420	79271655
Pain	38.31	10.86	475	77838	703327	78962748
Death	38.21	10.86	774	77539	565740	79100335
Urticaria	37.91	10.86	78	78235	185123	79480952
Device occlusion	37.44	10.86	52	78261	11814	79654261
Nasal dryness	37.38	10.86	33	78280	4530	79661545
Walking distance test abnormal	37.36	10.86	17	78296	721	79665354
Rhinocerebral mucormycosis	37.26	10.86	19	78294	1039	79665036
Oxygen saturation abnormal	37.26	10.86	33	78280	4549	79661526
Hospitalisation	37.14	10.86	187	78126	94049	79572026
Impaired healing	36.92	10.86	20	78293	87635	79578440
Irritable bowel syndrome	36.87	10.86	8	78305	62233	79603842
Catheter site haemorrhage	36.04	10.86	34	78279	5083	79660992
Exercise tolerance decreased	35.19	10.86	44	78269	9027	79657048
Left ventricular failure	34.84	10.86	45	78268	9536	79656539
Abdominal pain	34.68	10.86	232	78081	389337	79276738
Burns third degree	34.50	10.86	14	78299	447	79665628
Psoriasis	34.15	10.86	23	78290	89564	79576511
Malaise	33.92	10.86	672	77641	489197	79176878
Mucosal inflammation	33.69	10.86	16	78297	75564	79590511
Barotrauma	33.48	10.86	11	78302	189	79665886
Chest discomfort	33.29	10.86	241	78072	137803	79528272
Coma	33.10	10.86	30	78283	100619	79565456
Injection site erythema	32.70	10.86	18	78295	78179	79587896
Injection site reaction	32.54	10.86	7	78306	54778	79611297
Wound	32.20	10.86	40	78273	116139	79549936
Neuromuscular block prolonged	31.98	10.86	17	78296	1013	79665062
Device connection issue	31.71	10.86	17	78296	1031	79665044
Interstitial lung disease	31.56	10.86	204	78109	112396	79553679
Central venous catheterisation	31.46	10.86	26	78287	3263	79662812
Hypoglycaemia	31.41	10.86	32	78281	101562	79564513
Suicidal ideation	31.31	10.86	18	78295	76322	79589753
Blister	31.20	10.86	43	78270	119433	79546642
Pulmonary arterial pressure abnormal	31.10	10.86	15	78298	727	79665348
Pneumomediastinum	31.00	10.86	27	78286	3640	79662435
Carbon dioxide increased	30.86	10.86	22	78291	2218	79663857
Abdominal distension	30.67	10.86	212	78101	119438	79546637
Pulseless electrical activity	30.50	10.86	52	78261	14108	79651967
Leukopenia	30.36	10.86	42	78271	116471	79549604
Pulmonary alveolar haemorrhage	30.03	10.86	46	78267	11411	79654664
Tachypnoea	29.93	10.86	84	78229	31979	79634096
Catheter removal	29.65	10.86	14	78299	647	79665428
Idiopathic pulmonary fibrosis	29.60	10.86	28	78285	4200	79661875
Bronchitis	29.19	10.86	224	78089	130420	79535655
Red blood cell sedimentation rate increased	29.13	10.86	5	78308	45937	79620138
Atrial flutter	28.96	10.86	65	78248	21560	79644515
N-terminal prohormone brain natriuretic peptide increased	28.63	10.86	29	78284	4726	79661349
Cardiac ablation	28.47	10.86	21	78292	2232	79663843
COVID-19 pneumonia	28.33	10.86	77	78236	28772	79637303
Concomitant disease progression	28.21	10.86	25	78288	3448	79662627
Cognitive disorder	27.95	10.86	17	78296	69909	79596166
Catheter site scab	27.92	10.86	10	78303	225	79665850
Stevens-Johnson syndrome	27.82	10.86	3	78310	39163	79626912
Hyponatraemia	27.78	10.86	86	78227	177762	79488313
Paracentesis	27.76	10.86	17	78296	1328	79664747
Aggression	27.39	10.86	8	78305	50950	79615125
Aspiration pleural cavity	27.29	10.86	18	78295	1599	79664476
Malignant neoplasm progression	27.21	10.86	58	78255	135932	79530143
Depression	27.13	10.86	115	78198	216675	79449400
Cardiac pacemaker insertion	27.13	10.86	31	78282	5791	79660284
Accident	26.82	10.86	38	78275	8793	79657282
Osteonecrosis of jaw	26.77	10.86	5	78308	43221	79622854
Procedural complication	26.72	10.86	36	78277	7947	79658128
Catheter site warmth	26.60	10.86	10	78303	259	79665816
Neutrophil count decreased	26.41	10.86	32	78281	93927	79572148
Neoplasm progression	26.20	10.86	9	78304	51673	79614402
Congestive hepatopathy	26.06	10.86	27	78286	4520	79661555
Drug resistance	25.89	10.86	5	78308	42208	79623867
Acute kidney injury	25.84	10.86	357	77956	519047	79147028
Drug interaction	25.34	10.86	273	78040	414910	79251165
Fibromyalgia	25.22	10.86	16	78297	64324	79601751
Neuromuscular blockade	25.14	10.86	12	78301	568	79665507
Colitis	25.14	10.86	21	78292	73286	79592789
Catheter site inflammation	25.04	10.86	15	78298	1126	79664949
Catheter site swelling	25.01	10.86	18	78295	1842	79664233
Oedematous kidney	24.90	10.86	9	78304	208	79665867
Nocturnal dyspnoea	24.81	10.86	17	78296	1609	79664466
Heart rate increased	24.78	10.86	203	78110	120521	79545554
Cardiomegaly	24.56	10.86	69	78244	26283	79639792
Hepatitis	24.53	10.86	12	78301	55715	79610360
Sputum discoloured	24.39	10.86	61	78252	21682	79644393
Presyncope	24.24	10.86	92	78221	40962	79625113
Atrial fibrillation	24.23	10.86	299	78014	197587	79468488
C-reactive protein increased	24.21	10.86	57	78256	128970	79537105
Ventilation perfusion mismatch	24.02	10.86	12	78301	628	79665447
Respiratory acidosis	23.95	10.86	41	78272	11159	79654916
Injection site pruritus	23.93	10.86	6	78307	42277	79623798
Hypertension	23.83	10.86	209	78104	330783	79335292
Multiple sclerosis relapse	23.77	10.86	8	78305	46525	79619550
Acute right ventricular failure	23.75	10.86	10	78303	351	79665724
Liver injury	23.72	10.86	13	78300	56601	79609474
Hyperthermia malignant	23.70	10.86	21	78292	2896	79663179
Thrombocytopenia	23.57	10.86	158	78155	265101	79400974
Tracheostomy	23.53	10.86	15	78298	1257	79664818
Right ventricular dysfunction	23.49	10.86	20	78293	2615	79663460
Infusion site infection	23.41	10.86	17	78296	1764	79664311
Gamma-glutamyltransferase increased	23.32	10.86	111	78202	54569	79611506
Oxygen consumption	23.32	10.86	7	78306	88	79665987
Product use in unapproved indication	23.32	10.86	147	78166	250212	79415863
Peripheral swelling	23.25	10.86	383	77930	269234	79396841
Psychotic disorder	23.19	10.86	6	78307	41396	79624679
Pulmonary haemorrhage	22.89	10.86	47	78266	14670	79651405
White blood cell count decreased	22.88	10.86	101	78212	188187	79477888
Knee arthroplasty	22.86	10.86	7	78306	43241	79622834
SARS-CoV-2 viraemia	22.77	10.86	6	78307	45	79666030
Apnoea	22.64	10.86	41	78272	11663	79654412
Injection site swelling	22.56	10.86	9	78304	47123	79618952
Bone marrow failure	22.50	10.86	11	78302	51096	79614979
Tubulointerstitial nephritis	22.47	10.86	5	78308	38230	79627845
Device leakage	22.25	10.86	39	78274	10817	79655258
Product dose omission issue	22.22	10.86	354	77959	247183	79418892
Supraventricular tachycardia	22.13	10.86	58	78255	21212	79644863
Acute postoperative sialadenitis	22.10	10.86	6	78307	51	79666024
Infusion site erythema	22.06	10.86	36	78277	9424	79656651
Neuropathy peripheral	21.59	10.86	69	78244	141236	79524839
Colitis ulcerative	21.55	10.86	4	78309	34738	79631337
Catheter site granuloma	21.51	10.86	6	78307	57	79666018
Rhabdomyolysis	21.46	10.86	43	78270	103088	79562987
Mediastinal effusion	21.42	10.86	6	78307	58	79666017
Rhonchi	21.41	10.86	23	78290	4013	79662062
Secretion discharge	21.07	10.86	46	78267	14976	79651099
Pulmonary trichosporonosis	20.97	10.86	6	78307	63	79666012
Cold burn	20.94	10.86	4	78309	4	79666071
Pulmonary function test abnormal	20.91	10.86	23	78290	4121	79661954
Agranulocytosis	20.90	10.86	9	78304	45021	79621054
Cardiac disorder	20.85	10.86	123	78190	65634	79600441
Rhinorrhoea	20.81	10.86	137	78176	75937	79590138
Cytomegalovirus infection	20.64	10.86	8	78305	42636	79623439
Rash maculo-papular	20.57	10.86	15	78298	56063	79610012
Feeling abnormal	20.56	10.86	243	78070	158956	79507119
Angioplasty	20.53	10.86	16	78297	1847	79664228
Decreased activity	20.16	10.86	33	78280	8661	79657414
Anaesthetic complication cardiac	20.09	10.86	6	78307	74	79666001
Right-to-left cardiac shunt	20.06	10.86	8	78305	244	79665831
Paraesthesia	19.98	10.86	97	78216	176226	79489849
Myocardial infarction	19.90	10.86	103	78210	184026	79482049
Pancreatitis	19.65	10.86	23	78290	68552	79597523
PaO2/FiO2 ratio decreased	19.53	10.86	5	78308	33	79666042
Uterine hypotonus	19.40	10.86	6	78307	84	79665991
Therapy non-responder	19.36	10.86	156	78157	92149	79573926
Platelet transfusion	19.31	10.86	17	78296	2325	79663750
Product use issue	19.12	10.86	124	78189	209698	79456377
Paradoxical embolism	19.03	10.86	5	78308	37	79666038
Mouth ulceration	18.92	10.86	7	78306	38387	79627688
Mechanical ventilation	18.77	10.86	18	78295	2746	79663329
Exposure during pregnancy	18.71	10.86	45	78268	101087	79564988
Pulmonary artery banding	18.71	10.86	4	78309	10	79666065
Ventricular tachycardia	18.52	10.86	86	78227	41849	79624226
Hallucination	18.49	10.86	35	78278	85710	79580365
Pancreatitis haemorrhagic	18.44	10.86	11	78302	819	79665256
Abdominal cavity drainage	18.44	10.86	11	78302	819	79665256
Bronchospasm	18.38	10.86	60	78253	24799	79641276
Angioedema	18.26	10.86	29	78284	76006	79590069
Pulmonary artery dilatation	18.21	10.86	9	78304	460	79665615
Emergency care	18.13	10.86	12	78301	1072	79665003
Upper respiratory tract inflammation	17.99	10.86	21	78292	4014	79662061
Right ventricular enlargement	17.69	10.86	10	78303	673	79665402
Delayed recovery from anaesthesia	17.64	10.86	14	78299	1659	79664416
Aspartate aminotransferase increased	17.62	10.86	211	78102	138430	79527645
Blood alkaline phosphatase increased	17.62	10.86	115	78198	63549	79602526
Alkalosis hypochloraemic	17.60	10.86	9	78304	495	79665580
Iron deficiency anaemia	17.24	10.86	60	78253	25612	79640463
Glossoptosis	17.23	10.86	7	78306	224	79665851
Lower respiratory tract infection	17.13	10.86	67	78246	129153	79536922
Areflexia	17.08	10.86	24	78289	5510	79660565
Jugular vein distension	17.02	10.86	13	78300	1457	79664618
Seizure	17.00	10.86	112	78201	188722	79477353
Right ventricular systolic pressure increased	16.95	10.86	11	78302	951	79665124
Brain hypoxia	16.94	10.86	11	78302	952	79665123
Rotavirus infection	16.92	10.86	10	78303	732	79665343
Bursitis	16.90	10.86	7	78306	35837	79630238
Cerebral haemorrhage	16.89	10.86	19	78294	57654	79608421
Choking sensation	16.86	10.86	20	78293	3886	79662189
Osteoarthritis	16.83	10.86	38	78275	87271	79578804
Eosinophilia	16.80	10.86	12	78301	45333	79620742
Maternal exposure during pregnancy	16.73	10.86	73	78240	136465	79529610
Pulmonary capillary haemangiomatosis	16.72	10.86	5	78308	62	79666013
Urine output decreased	16.61	10.86	47	78266	17975	79648100
Lung assist device therapy	16.55	10.86	6	78307	140	79665935
Type 2 diabetes mellitus	16.54	10.86	19	78294	57103	79608972
Basal cell carcinoma	16.52	10.86	8	78305	37367	79628708
Joint range of motion decreased	16.52	10.86	6	78307	33276	79632799
Inappropriate antidiuretic hormone secretion	16.38	10.86	3	78310	26310	79639765
Myotonic dystrophy	16.35	10.86	6	78307	145	79665930
Injection site bruising	16.34	10.86	10	78303	40992	79625083
Jaundice	16.27	10.86	17	78296	53332	79612743
Catheter site irritation	16.22	10.86	9	78304	584	79665491
Exercise test abnormal	16.10	10.86	5	78308	71	79666004
Argon plasma coagulation	16.09	10.86	4	78309	23	79666052
Ascites	16.01	10.86	128	78185	75434	79590641
Ill-defined disorder	15.93	10.86	25	78288	65850	79600225
Proteinuria	15.89	10.86	6	78307	32496	79633579
Blood pressure increased	15.85	10.86	132	78181	211228	79454847
Dizziness postural	15.79	10.86	35	78278	11514	79654561
Cerebral infarction	15.76	10.86	13	78300	45663	79620412
Disturbance in attention	15.70	10.86	16	78297	50785	79615290
Emotional distress	15.58	10.86	10	78303	39959	79626116
Diabetic ketoacidosis	15.55	10.86	7	78306	34115	79631960
Sinus disorder	15.52	10.86	53	78260	22411	79643664
Device infusion issue	15.52	10.86	15	78298	2311	79663764
Complication associated with device	15.51	10.86	45	78268	17451	79648624
Poisoning	15.48	10.86	3	78310	25269	79640806
Frostbite	15.46	10.86	6	78307	170	79665905
Rales	15.44	10.86	49	78264	19952	79646123
Thyroglobulin increased	15.43	10.86	5	78308	82	79665993
Procedural hypotension	15.32	10.86	14	78299	2009	79664066
Head injury	15.32	10.86	75	78238	37294	79628781
Blood creatine phosphokinase increased	15.13	10.86	26	78287	66064	79600011
Middle ear effusion	15.04	10.86	15	78298	2400	79663675
Oedematous pancreatitis	15.02	10.86	11	78302	1157	79664918
Therapy interrupted	14.97	10.86	6	78307	31335	79634740
Cardioversion	14.89	10.86	14	78299	2084	79663991
Inflammation	14.87	10.86	45	78268	93708	79572367
Palmar-plantar erythrodysaesthesia syndrome	14.79	10.86	7	78306	33127	79632948
Sinus congestion	14.69	10.86	48	78265	19848	79646227
Multiple allergies	14.64	10.86	32	78281	10428	79655647
Pneumonia bacterial	14.60	10.86	47	78266	19284	79646791
Respiratory syncytial virus infection	14.59	10.86	30	78283	9372	79656703
Cutaneous mucormycosis	14.40	10.86	6	78307	205	79665870
Cholestasis	14.37	10.86	18	78295	52091	79613984
Localised oedema	14.31	10.86	27	78286	7925	79658150
Nasal operation	14.29	10.86	6	78307	209	79665866
Catheter site dermatitis	14.28	10.86	5	78308	105	79665970
Rehabilitation therapy	14.24	10.86	13	78300	1864	79664211
Catheter site hypersensitivity	14.15	10.86	5	78308	108	79665967
Lung infiltration	14.07	10.86	52	78261	22860	79643215
Cardiorenal syndrome	14.04	10.86	12	78301	1577	79664498
Weight increased	13.97	10.86	364	77949	277022	79389053
Right ventricular dilatation	13.95	10.86	13	78300	1913	79664162
Airway burns	13.63	10.86	3	78310	9	79666066
Hypercholesterolaemia	13.61	10.86	3	78310	23092	79642983
Diverticulitis	13.60	10.86	15	78298	45921	79620154
Hepatocellular injury	13.59	10.86	16	78297	47577	79618498
Oral herpes	13.54	10.86	5	78308	27449	79638626
Incorrect dose administered	13.47	10.86	35	78278	76595	79589480
Seasonal allergy	13.41	10.86	41	78272	16365	79649710
Terminal state	13.34	10.86	20	78293	4869	79661206
Myelosuppression	13.26	10.86	12	78301	40284	79625791
Sedation	13.22	10.86	19	78294	51876	79614199
Pulmonary pain	13.22	10.86	19	78294	4454	79661621
Loss of consciousness	13.17	10.86	235	78078	167708	79498367
Injury	13.17	10.86	36	78277	77460	79588615
Herpes zoster	13.16	10.86	47	78266	93036	79573039
Rash pruritic	13.15	10.86	32	78281	71597	79594478
Acute pulmonary oedema	13.00	10.86	37	78276	14193	79651882
Bradycardia	12.97	10.86	196	78117	135361	79530714
Gastrointestinal disorder	12.84	10.86	69	78244	122136	79543939
Drug level increased	12.82	10.86	12	78301	39639	79626436
Blood carbon monoxide increased	12.77	10.86	3	78310	13	79666062
Vena cava filter insertion	12.74	10.86	5	78308	146	79665929
Adverse drug reaction	12.71	10.86	29	78284	66363	79599712
Hospice care	12.69	10.86	30	78283	10294	79655781
Inappropriate schedule of product administration	12.67	10.86	78	78235	133550	79532525
Systemic scleroderma	12.59	10.86	10	78303	1187	79664888
Thoracic cavity drainage	12.51	10.86	6	78307	287	79665788
PO2 decreased	12.51	10.86	15	78298	2948	79663127
Swollen tongue	12.50	10.86	14	78299	42556	79623519
Pulmonary thrombosis	12.47	10.86	33	78280	12138	79653937
Mastitis bacterial	12.44	10.86	4	78309	64	79666011
Menstrual discomfort	12.42	10.86	3	78310	15	79666060
Medication error	12.34	10.86	31	78282	68611	79597464
Ventricular extrasystoles	12.33	10.86	45	78268	19659	79646416
Pulmonary vein stenosis	12.31	10.86	5	78308	160	79665915
Nightmare	12.27	10.86	5	78308	25856	79640219
Catheter site erosion	12.27	10.86	4	78309	67	79666008
Burns second degree	12.26	10.86	14	78299	2614	79663461
Stress cardiomyopathy	12.18	10.86	31	78282	11135	79654940
Gastrointestinal arteriovenous malformation	12.18	10.86	9	78304	959	79665116
Upper respiratory tract infection	12.14	10.86	140	78173	91028	79575047
Superinfection fungal	12.05	10.86	4	78309	71	79666004
Haemodynamic instability	12	10.86	41	78272	17341	79648734
Haematoma evacuation	11.94	10.86	6	78307	318	79665757
Retching	11.88	10.86	41	78272	17426	79648649
Blood triglycerides increased	11.88	10.86	3	78310	21037	79645038
Gastrointestinal tube insertion	11.80	10.86	11	78302	1619	79664456
Right ventricular hypertrophy	11.76	10.86	11	78302	1626	79664449
Hepatic cytolysis	11.72	10.86	6	78307	27145	79638930
Chronic left ventricular failure	11.72	10.86	9	78304	1017	79665058
Oesophageal dilation procedure	11.70	10.86	4	78309	78	79665997
Puncture site infection	11.70	10.86	4	78309	78	79665997
Right ventricular systolic pressure	11.69	10.86	3	78310	20	79666055
Catheter site vesicles	11.68	10.86	6	78307	333	79665742
Large intestinal polypectomy	11.67	10.86	6	78307	334	79665741
Cardiac septal defect repair	11.56	10.86	3	78310	21	79666054
Lung squamous cell carcinoma stage I	11.56	10.86	3	78310	21	79666054
Progressive multifocal leukoencephalopathy	11.51	10.86	3	78310	20597	79645478
Cardiomyopathy	11.49	10.86	7	78306	28767	79637308
Withdrawal syndrome	11.49	10.86	6	78307	26848	79639227
Tricuspid valve incompetence	11.49	10.86	44	78269	19668	79646407
Haematocrit decreased	11.47	10.86	101	78212	61211	79604864
Extrapyramidal disorder	11.41	10.86	4	78309	22675	79643400
Agonal respiration	11.38	10.86	4	78309	85	79665990
Hip arthroplasty	11.35	10.86	11	78302	35745	79630330
Breath sounds abnormal	11.30	10.86	38	78275	15946	79650129
PO2 abnormal	11.21	10.86	3	78310	24	79666051
Dizziness exertional	11.20	10.86	7	78306	567	79665508
Orthostatic hypotension	11.19	10.86	24	78289	56140	79609935
Respiration abnormal	11.10	10.86	24	78289	7764	79658311
Blood potassium decreased	11.09	10.86	81	78232	46431	79619644
Decreased appetite	11.08	10.86	426	77887	341992	79324083
Mineral supplementation	11.00	10.86	8	78305	832	79665243
Polyneuropathy	10.94	10.86	5	78308	24146	79641929
Hypophosphataemia	10.93	10.86	3	78310	19910	79646165
Paranasal sinus hypersecretion	10.88	10.86	16	78297	3830	79662245
Foot deformity	10.88	10.86	5	78308	24069	79642006

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	V03AN01	VARIOUS ALL OTHER THERAPEUTIC PRODUCTS ALL OTHER THERAPEUTIC PRODUCTS Medical gases
CHEBI has role	CHEBI:27027	trace elements
CHEBI has role	CHEBI:33284	nutrients
CHEBI has role	CHEBI:33893	reagent
CHEBI has role	CHEBI:35472	anti-inflammatory drugs
CHEBI has role	CHEBI:63248	oxidizer
CHEBI has role	CHEBI:75772	S. cerevisiae metabolites
CHEBI has role	CHEBI:77746	Homo sapiens metabolite
CHEBI has role	CHEBI:77974	food packaging gases
CHEBI has role	CHEBI:33937	macronutrients

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

Product	Applicant	Ingredients
None (Med Gas)	Air Liquide Industrial U.S. L.P.	2
None (Med Gas)	Air Liquide Large Industries U.S. L.P.	2
None (Med Gas)	Messer LLC	2
None (Med Gas)	Messer Canada Inc.	2
None (Med Gas)	Messer Gas Puerto Rico Inc.	2
None (Med Gas)	Norco Inc.	2
None (Med Gas)	Airgas Merchant Gases LLC	2
None (Med Gas)	Praxair Inc.	2
None (Med Gas)	Aspen Air, US Corp	2
None (Med Gas)	Air Products and Chemicals Inc.	2
None (Med Gas)	Air Liquide America L.P.	2
None (Med Gas)	Matheson Tri-Gas Inc.	2
None (Med Gas)	Praxair Canada Inc.	2
None (Med Gas)	Airgas USA LLC	2
None (Med Gas)	Praxair Mexico, S. de R.L. de C.V.	2

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

ID	Source
S88TT14065	UNII
4019105	VUID
N0000147362	NUI
D00003	KEGG_DRUG
4019105	VANDF
C0184633	UMLSCUI
CHEBI:25805	CHEBI
WEQ	PDB_CHEM_ID
CHEMBL1234886	ChEMBL_ID
977	PUBCHEM_CID
DB09140	DRUGBANK_ID
D010100	MESH_DESCRIPTOR_UI
7806	RXNORM
d06860	MMSL
000826	NDDF
24099007	SNOMEDCT_US
767111007	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10006-001	GAS	99 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
MEDICAL AIR	HUMAN PRESCRIPTION DRUG LABEL	1	10006-004	GAS	21 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
HELIOX	HUMAN PRESCRIPTION DRUG LABEL	1	10006-009	GAS	20 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
HELIOX	HUMAN PRESCRIPTION DRUG LABEL	1	10006-010	GAS	25 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
HELIOX	HUMAN PRESCRIPTION DRUG LABEL	1	10006-011	GAS	30 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10014-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10014-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen Helium Mixture	HUMAN PRESCRIPTION DRUG LABEL	2	10014-006	GAS	200 mL	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
Oxygen Helium Mixture 40/60	HUMAN PRESCRIPTION DRUG LABEL	2	10014-007	GAS	400 mL	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
Oxygen Helium Mixture 40/60	HUMAN PRESCRIPTION DRUG LABEL	1	10014-008	GAS	400 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen Helium Mixture	HUMAN PRESCRIPTION DRUG LABEL	1	10014-009	GAS	200 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen Helium Mixture 30/70	HUMAN PRESCRIPTION DRUG LABEL	1	10014-018	GAS	300 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10018-8999	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10073-111	GAS	992 mL	RESPIRATORY (INHALATION)	NDA	1 sections
oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10073-111	GAS	992 mL	RESPIRATORY (INHALATION)	NDA	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10109-1234	GAS	99 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10163-0202	GAS	99 L	RESPIRATORY (INHALATION)	unapproved medical gas	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10167-100	GAS	99 L	RESPIRATORY (INHALATION)	NDA	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10167-100	GAS	99 L	RESPIRATORY (INHALATION)	NDA	1 sections
AIR COMPRESSED	HUMAN PRESCRIPTION DRUG LABEL	1	10167-600	GAS	20 L	RESPIRATORY (INHALATION)	NDA	1 sections
AIR COMPRESSED	HUMAN PRESCRIPTION DRUG LABEL	1	10167-600	GAS	20 L	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10189-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10189-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10218-001	GAS	995 mL	RESPIRATORY (INHALATION)	NDA	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10218-001	GAS	995 mL	RESPIRATORY (INHALATION)	NDA	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10221-001	GAS	992 mL	RESPIRATORY (INHALATION)	NDA	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10221-001	GAS	992 mL	RESPIRATORY (INHALATION)	NDA	1 sections
OXYGEN	HUMAN PRESCRIPTION DRUG LABEL	1	10221-001	GAS	992 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10252-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections
Oxygen	HUMAN PRESCRIPTION DRUG LABEL	1	10252-001	GAS	990 mL	RESPIRATORY (INHALATION)	NDA	1 sections