octisalate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4241 118-60-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • octisalate
  • octyl salicylate
  • Molecular weight: 250.34
  • Formula: C15H22O3
  • CLOGP: 5.91
  • LIPINSKI: 1
  • HAC: 3
  • HDO: 1
  • TPSA: 46.53
  • ALOGS: -4.02
  • ROTB: 8

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Macular degeneration 497.81 20.74 114 1824 14274 50588912
Drug ineffective 91.73 20.74 132 1806 819201 49783985
Chronic sinusitis 27.75 20.74 10 1928 6135 50597051
Paraesthesia oral 27.43 20.74 12 1926 12209 50590977
Jarisch-Herxheimer reaction 25.48 20.74 5 1933 290 50602896
Dermatophytosis 21.94 20.74 4 1934 156 50603030

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Macular degeneration 31.08 18.86 11 2766 5699 64490256
Pyrexia 25.00 18.86 66 2711 558578 63937377
Chronic sinusitis 22.81 18.86 9 2768 6283 64489672
Paraesthesia oral 22.24 18.86 11 2766 13120 64482835
Jarisch-Herxheimer reaction 20.69 18.86 5 2772 682 64495273

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.9 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4X49Y0596W UNII
4025698 VUID
N0000179486 NUI
D05226 KEGG_DRUG
4020295 VANDF
4025698 VANDF
C0304632 UMLSCUI
CHEBI:88639 CHEBI
CHEMBL1329203 ChEMBL_ID
8364 PUBCHEM_CID
DB11062 DRUGBANK_ID
7940 INN_ID
91327 RXNORM
006876 NDDF
29622009 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 34 Sunscreen HUMAN OTC DRUG LABEL 3 0023-5494 LOTION 30 mg TOPICAL OTC monograph not final 12 sections
TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 34 Sunscreen (Tinted) HUMAN OTC DRUG LABEL 4 0023-5497 LOTION 30 mg TOPICAL OTC monograph not final 12 sections
TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 50 Sunscreen HUMAN OTC DRUG LABEL 4 0023-5501 LOTION 50 mg TOPICAL OTC monograph not final 8 sections
Purpose HUMAN OTC DRUG LABEL 3 0187-5500 LOTION 50 mg TOPICAL OTC monograph not final 9 sections
Cetaphil Daily Facial Moisturizer with suncreen SPF 35 HUMAN OTC DRUG LABEL 4 0299-4113 LOTION 48 mg TOPICAL OTC monograph final 12 sections
Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 HUMAN OTC DRUG LABEL 4 0299-4118 LOTION 50 mg TOPICAL OTC monograph final 12 sections
Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 HUMAN OTC DRUG LABEL 4 0299-4118 LOTION 50 mg TOPICAL OTC monograph final 12 sections
Cetaphil Oil Absorbing SPF 30 HUMAN OTC DRUG LABEL 3 0299-4123 LOTION 5 g TOPICAL OTC monograph final 8 sections
Cetaphil Oil Absorbing SPF 30 HUMAN OTC DRUG LABEL 3 0299-4123 LOTION 5 g TOPICAL OTC monograph final 8 sections
Differin Oil Absorbing Moisturizer SPF 30 HUMAN OTC DRUG LABEL 3 0299-4133 LOTION 5 g TOPICAL OTC monograph final 9 sections
Cetaphil PRO Oil Absorbing SPF 30 HUMAN OTC DRUG LABEL 3 0299-4313 LOTION 5 g TOPICAL OTC monograph final 8 sections
Differin Oil Absorbing Moisturizer SPF 30 HUMAN OTC DRUG LABEL 3 0299-4607 LOTION 5 g TOPICAL OTC monograph final 9 sections
Differin Oil Absorbing Moisturizer SPF 30 HUMAN OTC DRUG LABEL 3 0299-4607 LOTION 5 g TOPICAL OTC monograph final 9 sections
Cetaphil Daily Facial Moisturizer with suncreen SPF 50 HUMAN OTC DRUG LABEL 5 0299-4930 LOTION 50 mg TOPICAL OTC monograph final 11 sections
Cetaphil Daily Facial Moisturizer with suncreen SPF 50 HUMAN OTC DRUG LABEL 5 0299-4930 LOTION 50 mg TOPICAL OTC monograph final 11 sections
Almay Smart Shade CC Cream HUMAN OTC DRUG LABEL 3 0311-0705 LIQUID 5 mg TOPICAL OTC monograph final 6 sections
Almay Anti Aging Lip Care SPF 20 HUMAN OTC DRUG LABEL 5 0311-0709 LIPSTICK 5 mg TOPICAL OTC monograph final 8 sections
Almay Best Blend Forever Makeup HUMAN OTC DRUG LABEL 4 0311-0719 LOTION 5 mg TOPICAL OTC monograph final 5 sections
Almay Healthy Biome Makeup HUMAN OTC DRUG LABEL 5 0311-0723 EMULSION 5 mg TOPICAL OTC monograph final 7 sections
Blue Lizard Kids SPF 50 Sunscreen HUMAN OTC DRUG LABEL 3 0316-2062 LOTION 55.50 mg TOPICAL OTC monograph not final 9 sections
Blue Lizard Active SPF 50 Sunscreen HUMAN OTC DRUG LABEL 3 0316-2072 LOTION 55.50 mg TOPICAL OTC monograph not final 9 sections
Blue Lizard Sport SPF 50 Sunscreen HUMAN OTC DRUG LABEL 3 0316-2075 LOTION 55.50 mg TOPICAL OTC monograph not final 9 sections
Hydrating Antioxidant Moiturizer HUMAN OTC DRUG LABEL 4 0363-0540 CREAM 4.72 g TOPICAL OTC monograph not final 11 sections
Walgreens 7-in-1 Anti-Aging Vitamin Complex Broad Spectrum SPF 15 Sunscreen HUMAN OTC DRUG LABEL 3 0363-0692 CREAM 5 mg TOPICAL OTC monograph not final 12 sections
Walgreens Advanced Anti-Wrinkle and Firming Day Cream Broad Spectrum SPF18 Sunscreen HUMAN OTC DRUG LABEL 3 0363-0815 CREAM 5 g TOPICAL OTC monograph not final 11 sections
WALGREEN SPORT SPF 70 SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0900 LOTION 30 mg TOPICAL OTC monograph not final 12 sections
WALGREENS SPORT SPF 50 SUNSCREEN HUMAN OTC DRUG LABEL 4 0363-0924 AEROSOL, SPRAY 50 mg TOPICAL OTC monograph not final 13 sections
WALGREENS BROAD SPECTRUM SPF 110 AGE PROTECTION SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0933 LOTION 50 mg TOPICAL OTC monograph not final 12 sections
WALGREENS BROAD SPECTRUM SPF 70 SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0936 STICK 50 mg TOPICAL OTC monograph not final 11 sections
WALGREENS SPORT BROAD SPECTRUM SPF 50 FACES SUNSCREEN HUMAN OTC DRUG LABEL 5 0363-0937 LOTION 50 mg TOPICAL OTC monograph not final 13 sections