octisalate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 4241 | 118-60-5 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Macular degeneration | 497.81 | 20.74 | 114 | 1824 | 14274 | 50588912 |
| Drug ineffective | 91.73 | 20.74 | 132 | 1806 | 819201 | 49783985 |
| Chronic sinusitis | 27.75 | 20.74 | 10 | 1928 | 6135 | 50597051 |
| Paraesthesia oral | 27.43 | 20.74 | 12 | 1926 | 12209 | 50590977 |
| Jarisch-Herxheimer reaction | 25.48 | 20.74 | 5 | 1933 | 290 | 50602896 |
| Dermatophytosis | 21.94 | 20.74 | 4 | 1934 | 156 | 50603030 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Macular degeneration | 31.08 | 18.86 | 11 | 2766 | 5699 | 64490256 |
| Pyrexia | 25.00 | 18.86 | 66 | 2711 | 558578 | 63937377 |
| Chronic sinusitis | 22.81 | 18.86 | 9 | 2768 | 6283 | 64489672 |
| Paraesthesia oral | 22.24 | 18.86 | 11 | 2766 | 13120 | 64482835 |
| Jarisch-Herxheimer reaction | 20.69 | 18.86 | 5 | 2772 | 682 | 64495273 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.9 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4X49Y0596W | UNII |
| 4025698 | VUID |
| N0000179486 | NUI |
| D05226 | KEGG_DRUG |
| 4020295 | VANDF |
| 4025698 | VANDF |
| C0304632 | UMLSCUI |
| CHEBI:88639 | CHEBI |
| CHEMBL1329203 | ChEMBL_ID |
| 8364 | PUBCHEM_CID |
| DB11062 | DRUGBANK_ID |
| 7940 | INN_ID |
| 91327 | RXNORM |
| 006876 | NDDF |
| 29622009 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 34 Sunscreen | HUMAN OTC DRUG LABEL | 3 | 0023-5494 | LOTION | 30 mg | TOPICAL | OTC monograph not final | 12 sections |
| TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 34 Sunscreen (Tinted) | HUMAN OTC DRUG LABEL | 4 | 0023-5497 | LOTION | 30 mg | TOPICAL | OTC monograph not final | 12 sections |
| TOTAL DEFENSE REPAIR BROAD SPECTRUM SPF 50 Sunscreen | HUMAN OTC DRUG LABEL | 4 | 0023-5501 | LOTION | 50 mg | TOPICAL | OTC monograph not final | 8 sections |
| Purpose | HUMAN OTC DRUG LABEL | 3 | 0187-5500 | LOTION | 50 mg | TOPICAL | OTC monograph not final | 9 sections |
| Cetaphil Daily Facial Moisturizer with suncreen SPF 35 | HUMAN OTC DRUG LABEL | 4 | 0299-4113 | LOTION | 48 mg | TOPICAL | OTC monograph final | 12 sections |
| Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 | HUMAN OTC DRUG LABEL | 4 | 0299-4118 | LOTION | 50 mg | TOPICAL | OTC monograph final | 12 sections |
| Cetaphil Healthy Radiance Whipped Day Cream Broad Spectrum SPF 30 | HUMAN OTC DRUG LABEL | 4 | 0299-4118 | LOTION | 50 mg | TOPICAL | OTC monograph final | 12 sections |
| Cetaphil Oil Absorbing SPF 30 | HUMAN OTC DRUG LABEL | 3 | 0299-4123 | LOTION | 5 g | TOPICAL | OTC monograph final | 8 sections |
| Cetaphil Oil Absorbing SPF 30 | HUMAN OTC DRUG LABEL | 3 | 0299-4123 | LOTION | 5 g | TOPICAL | OTC monograph final | 8 sections |
| Differin Oil Absorbing Moisturizer SPF 30 | HUMAN OTC DRUG LABEL | 3 | 0299-4133 | LOTION | 5 g | TOPICAL | OTC monograph final | 9 sections |
| Cetaphil PRO Oil Absorbing SPF 30 | HUMAN OTC DRUG LABEL | 3 | 0299-4313 | LOTION | 5 g | TOPICAL | OTC monograph final | 8 sections |
| Differin Oil Absorbing Moisturizer SPF 30 | HUMAN OTC DRUG LABEL | 3 | 0299-4607 | LOTION | 5 g | TOPICAL | OTC monograph final | 9 sections |
| Differin Oil Absorbing Moisturizer SPF 30 | HUMAN OTC DRUG LABEL | 3 | 0299-4607 | LOTION | 5 g | TOPICAL | OTC monograph final | 9 sections |
| Cetaphil Daily Facial Moisturizer with suncreen SPF 50 | HUMAN OTC DRUG LABEL | 5 | 0299-4930 | LOTION | 50 mg | TOPICAL | OTC monograph final | 11 sections |
| Cetaphil Daily Facial Moisturizer with suncreen SPF 50 | HUMAN OTC DRUG LABEL | 5 | 0299-4930 | LOTION | 50 mg | TOPICAL | OTC monograph final | 11 sections |
| Almay Smart Shade CC Cream | HUMAN OTC DRUG LABEL | 3 | 0311-0705 | LIQUID | 5 mg | TOPICAL | OTC monograph final | 6 sections |
| Almay Anti Aging Lip Care SPF 20 | HUMAN OTC DRUG LABEL | 5 | 0311-0709 | LIPSTICK | 5 mg | TOPICAL | OTC monograph final | 8 sections |
| Almay Best Blend Forever Makeup | HUMAN OTC DRUG LABEL | 4 | 0311-0719 | LOTION | 5 mg | TOPICAL | OTC monograph final | 5 sections |
| Almay Healthy Biome Makeup | HUMAN OTC DRUG LABEL | 5 | 0311-0723 | EMULSION | 5 mg | TOPICAL | OTC monograph final | 7 sections |
| Blue Lizard Kids SPF 50 Sunscreen | HUMAN OTC DRUG LABEL | 3 | 0316-2062 | LOTION | 55.50 mg | TOPICAL | OTC monograph not final | 9 sections |
| Blue Lizard Active SPF 50 Sunscreen | HUMAN OTC DRUG LABEL | 3 | 0316-2072 | LOTION | 55.50 mg | TOPICAL | OTC monograph not final | 9 sections |
| Blue Lizard Sport SPF 50 Sunscreen | HUMAN OTC DRUG LABEL | 3 | 0316-2075 | LOTION | 55.50 mg | TOPICAL | OTC monograph not final | 9 sections |
| Hydrating Antioxidant Moiturizer | HUMAN OTC DRUG LABEL | 4 | 0363-0540 | CREAM | 4.72 g | TOPICAL | OTC monograph not final | 11 sections |
| Walgreens 7-in-1 Anti-Aging Vitamin Complex Broad Spectrum SPF 15 Sunscreen | HUMAN OTC DRUG LABEL | 3 | 0363-0692 | CREAM | 5 mg | TOPICAL | OTC monograph not final | 12 sections |
| Walgreens Advanced Anti-Wrinkle and Firming Day Cream Broad Spectrum SPF18 Sunscreen | HUMAN OTC DRUG LABEL | 3 | 0363-0815 | CREAM | 5 g | TOPICAL | OTC monograph not final | 11 sections |
| WALGREEN SPORT SPF 70 SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0900 | LOTION | 30 mg | TOPICAL | OTC monograph not final | 12 sections |
| WALGREENS SPORT SPF 50 SUNSCREEN | HUMAN OTC DRUG LABEL | 4 | 0363-0924 | AEROSOL, SPRAY | 50 mg | TOPICAL | OTC monograph not final | 13 sections |
| WALGREENS BROAD SPECTRUM SPF 110 AGE PROTECTION SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0933 | LOTION | 50 mg | TOPICAL | OTC monograph not final | 12 sections |
| WALGREENS BROAD SPECTRUM SPF 70 SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0936 | STICK | 50 mg | TOPICAL | OTC monograph not final | 11 sections |
| WALGREENS SPORT BROAD SPECTRUM SPF 50 FACES SUNSCREEN | HUMAN OTC DRUG LABEL | 5 | 0363-0937 | LOTION | 50 mg | TOPICAL | OTC monograph not final | 13 sections |