diatrizoate meglumine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
radiopharmaceuticals, iodine-contained 4208 131-49-7

Description:

MoleculeDescription

Synonyms:

  • meglumine amidotrizoate
  • diatrizoate meglumine
  • amidotrizoic acid methylglucamine salt
  • angiografin
  • diatrizoate methylglucamine
  • gastrografin
A versatile contrast medium used for DIAGNOSTIC X-RAY RADIOLOGY.
  • Molecular weight: 809.13
  • Formula: C18H26I3N3O9
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA: 98.33
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

PropertyValueReference
MRTD (Maximum Recommended Therapeutic Daily Dose) 652.40 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD

Approvals:

DateAgencyCompanyOrphan
Aug. 2, 1955 FDA BRACCO

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Urticaria 57.21 53.10 21 213 185180 79558974

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals
CHEBI has role CHEBI:37338 contrast media

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017587 VUID
N0000145968 NUI
D02015 KEGG_DRUG
4017587 VANDF
C0012005 UMLSCUI
CHEBI:31812 CHEBI
CHEMBL1200839 ChEMBL_ID
D003974 MESH_DESCRIPTOR_UI
3X9MR4N98U UNII
8566 PUBCHEM_CID
3320 RXNORM
4571 MMSL
508 MMSL
58100 MMSL
798 MMSL
002343 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
MD GASTROVIEW HUMAN PRESCRIPTION DRUG LABEL 2 0019-4816 SOLUTION 600 mg ORAL ANDA 19 sections
Cystografin HUMAN PRESCRIPTION DRUG LABEL 1 0270-0149 INJECTION, SOLUTION 300 mg INTRAVENOUS NDA 12 sections
Gastrografin HUMAN PRESCRIPTION DRUG LABEL 2 0270-0445 LIQUID 660 mg ORAL NDA 20 sections
Cystografin Dilute HUMAN PRESCRIPTION DRUG LABEL 1 0270-1410 INJECTION, SOLUTION 180 mg INTRAVESICAL NDA 12 sections
Diatrizoate Meglumine and Diatrizoate Sodium Human Prescription Drug Label 2 53041-688 SOLUTION 660 mg ORAL ANDA 18 sections
Diatrizoate Meglumine and Diatrizoate Sodium Human Prescription Drug Label 2 53041-690 SOLUTION 660 mg ORAL ANDA 18 sections