sodium bicarbonate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4205 144-55-8

Description:

MoleculeDescription

Synonyms:

  • sodium bicarbonate
  • sodium hydrogen carbonate
A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
  • Molecular weight: 84.01
  • Formula: CHNaO3
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Oct. 28, 1981 FDA ALCON

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Acute kidney injury 209.68 11.94 382 23624 227676 50353442
Renal impairment 164.70 11.94 191 23815 75470 50505648
Metabolic alkalosis 141.35 11.94 52 23954 2679 50578439
Renal failure 127.37 11.94 201 23805 106432 50474686
Metabolic acidosis 127.31 11.94 122 23884 38703 50542415
Hyperkalaemia 92.40 11.94 114 23892 47975 50533143
Blood creatinine increased 91.48 11.94 144 23862 76016 50505102
Anaemia 81.56 11.94 284 23722 252172 50328946
Arthralgia 72.71 11.94 61 23945 438641 50142477
Renal injury 71.94 11.94 47 23959 8564 50572554
Drug intolerance 66.21 11.94 12 23994 219092 50362026
Blood urea increased 65.97 11.94 68 23938 23517 50557601
Rheumatoid arthritis 63.61 11.94 10 23996 202540 50378578
Arthropathy 56.48 11.94 5 24001 157901 50423217
Bradycardia 54.04 11.94 104 23902 64322 50516796
Hypokalaemia 53.99 11.94 125 23881 87867 50493251
Circulatory collapse 52.95 11.94 56 23950 19944 50561174
Hypotension 51.80 11.94 235 23771 235234 50345884
Alopecia 51.48 11.94 26 23980 245021 50336097
Contraindicated product administered 49.95 11.94 6 24000 148952 50432166
Electrocardiogram QRS complex prolonged 49.17 11.94 31 23975 5313 50575805
Macular degeneration 48.63 11.94 46 23960 14342 50566776
Fatigue 47.89 11.94 174 23832 707427 49873691
Chronic kidney disease 47.44 11.94 75 23931 39696 50541422
Lactic acidosis 47.03 11.94 68 23938 33287 50547831
Joint swelling 45.85 11.94 30 23976 245256 50335862
Anhedonia 43.26 11.94 36 23970 9488 50571630
Multiple organ dysfunction syndrome 41.89 11.94 81 23925 50256 50530862
Drug hypersensitivity 41.37 11.94 35 23971 250975 50330143
Acidosis 41.02 11.94 36 23970 10191 50570927
Therapeutic product effect decreased 39.90 11.94 8 23998 136042 50445076
Drug clearance decreased 38.62 11.94 16 23990 1133 50579985
Swelling 38.30 11.94 24 23982 200848 50380270
Haemodynamic instability 37.84 11.94 31 23975 7993 50573125
Systemic lupus erythematosus 37.80 11.94 10 23996 140612 50440506
Cardiac arrest 36.94 11.94 105 23901 83546 50497572
Hypocalcaemia 36.83 11.94 54 23952 26762 50554356
Product administration error 36.69 11.94 46 23960 19653 50561465
Treatment failure 36.59 11.94 10 23996 137627 50443491
Respiratory failure 35.09 11.94 109 23897 91072 50490046
Hyperchloraemia 34.99 11.94 13 23993 688 50580430
Sinusitis 34.46 11.94 19 23987 170539 50410579
Ventricular fibrillation 34.24 11.94 33 23973 10526 50570592
Wound 31.48 11.94 6 24000 105788 50475330
Glossodynia 31.47 11.94 8 23998 115561 50465557
Hepatic enzyme increased 31.27 11.94 13 23993 137367 50443751
Rash 31.21 11.94 105 23901 437366 50143752
Shock 30.43 11.94 43 23963 20607 50560511
Monoplegia 30.35 11.94 18 23988 2765 50578353
Central nervous system injury 30.18 11.94 8 23998 136 50580982
Crystal nephropathy 29.61 11.94 12 23994 803 50580315
Abdominal discomfort 29.57 11.94 40 23966 231601 50349517
Urine chloride decreased 29.06 11.94 7 23999 79 50581039
Fear 28.74 11.94 35 23971 14514 50566604
Cardiogenic shock 28.37 11.94 36 23970 15563 50565555
Haemoglobin decreased 27.94 11.94 127 23879 127089 50454029
Thrombocytopenia 27.70 11.94 127 23879 127546 50453572
Splenic injury 27.69 11.94 8 23998 189 50580929
Hypochromasia 27.62 11.94 9 23997 321 50580797
Nephrogenic systemic fibrosis 27.61 11.94 20 23986 4302 50576816
Sepsis 27.21 11.94 130 23876 132795 50448323
Discomfort 26.77 11.94 9 23997 108371 50472747
Hypoxia 26.40 11.94 68 23938 51055 50530063
Musculoskeletal stiffness 26.40 11.94 14 23992 128467 50452651
Peritonitis bacterial 26.26 11.94 20 23986 4641 50576477
Status epilepticus 26.08 11.94 32 23974 13374 50567744
Enzyme induction 25.94 11.94 6 24000 56 50581062
Septic shock 25.46 11.94 72 23934 57103 50524015
Ventricular tachycardia 24.89 11.94 34 23972 15787 50565331
Drug level above therapeutic 24.73 11.94 18 23988 3902 50577216
Urine sodium decreased 24.70 11.94 7 23999 154 50580964
End stage renal disease 24.64 11.94 21 23985 5716 50575402
Weight increased 24.62 11.94 36 23970 201855 50379263
Kidney transplant rejection 24.45 11.94 18 23988 3969 50577149
Dialysis 24.22 11.94 26 23980 9412 50571706
Nasopharyngitis 23.92 11.94 34 23972 192893 50388225
Overdose 23.74 11.94 102 23904 99625 50481493
Tumour lysis syndrome 23.70 11.94 23 23983 7398 50573720
Dehydration 23.58 11.94 138 23868 152311 50428807
Neutrophil count increased 23.08 11.94 31 23975 14164 50566954
Hypernatraemia 22.88 11.94 21 23985 6300 50574818
Unresponsive to stimuli 22.75 11.94 47 23959 30562 50550556
Hypervolaemia 22.40 11.94 42 23964 25457 50555661
Hypersensitivity 21.97 11.94 43 23963 215118 50366000
Infusion related reaction 21.91 11.94 29 23977 169528 50411590
Haemolysis 21.80 11.94 20 23986 5996 50575122
Cardiac assistance device user 21.78 11.94 5 24001 45 50581073
Blood phosphorus increased 21.34 11.94 14 23992 2568 50578550
Endometritis 21.20 11.94 10 23996 965 50580153
Drug level increased 21.15 11.94 35 23971 19233 50561885
Postresuscitation encephalopathy 21.08 11.94 4 24002 12 50581106
Psoriasis 20.34 11.94 4 24002 68996 50512122
Product prescribing error 20.28 11.94 36 23970 20925 50560193
Lymphocyte count decreased 20.27 11.94 41 23965 26266 50554852
Generalised tonic-clonic seizure 20.26 11.94 41 23965 26269 50554849
Headache 20.26 11.94 149 23857 506386 50074732
Pulmonary interstitial emphysema syndrome 19.96 11.94 3 24003 0 50581118
Hypoalbuminaemia 19.93 11.94 24 23982 9836 50571282
Wrong product administered 19.78 11.94 18 23988 5342 50575776
Haemodialysis 19.66 11.94 22 23984 8340 50572778
Anisocytosis 19.22 11.94 8 23998 573 50580545
Febrile bone marrow aplasia 19.11 11.94 19 23987 6292 50574826
Pain in extremity 19.07 11.94 66 23940 272799 50308319
Acute respiratory distress syndrome 18.84 11.94 35 23971 21064 50560054
Impaired healing 18.67 11.94 5 24001 69781 50511337
Peripheral swelling 18.66 11.94 44 23962 205892 50375226
Encephalopathy 18.61 11.94 46 23960 33665 50547453
Tubulointerstitial nephritis 18.57 11.94 29 23977 15182 50565936
Cardiovascular insufficiency 18.34 11.94 10 23996 1310 50579808
Intestinal ischaemia 18.02 11.94 19 23987 6738 50574380
Incision site pain 17.87 11.94 9 23997 1002 50580116
Emotional distress 17.87 11.94 41 23965 28622 50552496
Vascular parkinsonism 17.82 11.94 5 24001 106 50581012
Protein urine present 17.80 11.94 17 23989 5360 50575758
Neonatal hypotension 17.35 11.94 5 24001 117 50581001
Disseminated intravascular coagulation 17.31 11.94 30 23976 17105 50564013
Ileus 17.24 11.94 26 23980 13203 50567915
Toxicity to various agents 17.20 11.94 165 23841 212334 50368784
Nephropathy toxic 16.98 11.94 20 23986 8009 50573109
Accidental overdose 16.94 11.94 32 23974 19501 50561617
Pleural effusion 16.90 11.94 80 23926 81374 50499744
Vomiting 16.73 11.94 309 23697 460449 50120669
Hyperaemia 16.66 11.94 11 23995 2039 50579079
Injury 16.56 11.94 56 23950 48869 50532249
Refractory cytopenia with unilineage dysplasia 16.54 11.94 7 23999 523 50580595
Mental status changes 16.46 11.94 46 23960 36226 50544892
Osteoarthritis 16.42 11.94 6 24000 68600 50512518
N-terminal prohormone brain natriuretic peptide 16.30 11.94 4 24002 49 50581069
Acidosis hyperchloraemic 15.89 11.94 6 24000 332 50580786
Red blood cells urine positive 15.84 11.94 12 23994 2763 50578355
Sulphaemoglobinaemia 15.81 11.94 3 24003 9 50581109
Atrioventricular block first degree 15.77 11.94 17 23989 6184 50574934
Euglycaemic diabetic ketoacidosis 15.67 11.94 12 23994 2807 50578311
Local anaesthetic systemic toxicity 15.57 11.94 7 23999 605 50580513
General physical health deterioration 15.41 11.94 118 23888 142316 50438802
Aplasia pure red cell 15.25 11.94 14 23992 4201 50576917
Renal lymphocele 15.20 11.94 4 24002 66 50581052
Coagulopathy 15.07 11.94 29 23977 17915 50563203
Talipes 15.04 11.94 9 23997 1405 50579713
Milk-alkali syndrome 14.82 11.94 7 23999 678 50580440
pH body fluid abnormal 14.62 11.94 4 24002 77 50581041
Respiratory alkalosis 14.62 11.94 11 23995 2508 50578610
Insomnia 14.56 11.94 39 23967 174826 50406292
Haemorrhage 14.56 11.94 57 23949 53384 50527734
Pulseless electrical activity 14.40 11.94 17 23989 6824 50574294
Pulmonary embolism 14.40 11.94 90 23916 101614 50479504
Tongue oedema 14.38 11.94 13 23993 3826 50577292
Accident at work 14.33 11.94 6 24000 436 50580682
Cerebral haematoma 14.29 11.94 12 23994 3199 50577919
Blood albumin abnormal 14.14 11.94 6 24000 451 50580667
Sensitisation 14.11 11.94 9 23997 1573 50579545
Urinary tract infection pseudomonal 13.84 11.94 7 23999 786 50580332
Peritoneal dialysis complication 13.83 11.94 8 23998 1173 50579945
Arteriovenous fistula site complication 13.70 11.94 6 24000 487 50580631
Activated partial thromboplastin time prolonged 13.63 11.94 16 23990 6386 50574732
Electrolyte imbalance 13.51 11.94 27 23979 17142 50563976
Urine phosphorus increased 13.38 11.94 3 24003 24 50581094
Pain 13.34 11.94 194 23812 578709 50002409
Hypothyroidism 13.30 11.94 41 23965 34084 50547034
Irritable bowel syndrome 13.18 11.94 4 24002 51437 50529681
Blood potassium increased 13.16 11.94 26 23980 16372 50564746
Ovarian cancer recurrent 13.14 11.94 7 23999 875 50580243
Neonatal disorder 12.95 11.94 6 24000 556 50580562
Hypovolaemia 12.90 11.94 19 23987 9446 50571672
Mallory-Weiss syndrome 12.79 11.94 8 23998 1352 50579766
Brain injury 12.75 11.94 15 23991 5999 50575119
Hyperphosphataemia 12.74 11.94 9 23997 1862 50579256
Tachycardia 12.72 11.94 86 23920 99677 50481441
Immunosuppressant drug level increased 12.66 11.94 11 23995 3071 50578047
Diffuse alopecia 12.61 11.94 6 24000 590 50580528
Acute lung injury 12.61 11.94 8 23998 1385 50579733
Cholecystitis chronic 12.60 11.94 19 23987 9650 50571468
Ischaemic hepatitis 12.49 11.94 9 23997 1920 50579198
Urticaria 12.28 11.94 27 23979 129534 50451584
Systolic dysfunction 12.21 11.94 8 23998 1464 50579654
Newborn persistent pulmonary hypertension 12.19 11.94 4 24002 146 50580972
Enterocolitis infectious 12.18 11.94 8 23998 1470 50579648
Stag horn calculus 12.14 11.94 4 24002 148 50580970
Cytomegalovirus viraemia 12.13 11.94 13 23993 4696 50576422
Feeling abnormal 12.02 11.94 26 23980 125466 50455652
Azotaemia 12.01 11.94 12 23994 3996 50577122
Intentional overdose 11.96 11.94 60 23946 62444 50518674
Product use issue 11.95 11.94 34 23972 149441 50431677

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Renal impairment 139.20 11.64 255 26056 81078 29467138
Renal failure 117.63 11.64 298 26013 118301 29429915
Metabolic acidosis 108.60 11.64 150 26161 37512 29510704
Acute kidney injury 105.23 11.64 490 25821 264777 29283439
Lymphocyte count decreased 93.63 11.64 100 26211 19171 29529045
Blood creatinine increased 79.27 11.64 209 26102 84893 29463323
Fear 78.14 11.64 66 26245 9438 29538778
Chronic kidney disease 65.77 11.64 117 26194 36299 29511917
Incision site pain 65.74 11.64 32 26279 1751 29546465
Anhedonia 61.25 11.64 51 26260 7149 29541067
Blood urea increased 59.59 11.64 97 26214 28015 29520201
Hyperkalaemia 57.35 11.64 151 26160 61241 29486975
Renal injury 55.02 11.64 56 26255 10146 29538070
Multiple organ dysfunction syndrome 49.82 11.64 146 26165 62970 29485246
Hypochromasia 49.30 11.64 16 26295 293 29547923
Injury 49.17 11.64 72 26239 18974 29529242
Delayed graft function 49.16 11.64 27 26284 1900 29546316
Neutrophil count increased 44.39 11.64 60 26251 14682 29533534
Red blood cells urine positive 44.23 11.64 24 26287 1649 29546567
Hyperparathyroidism secondary 41.43 11.64 21 26290 1254 29546962
Emotional distress 41 11.64 56 26255 13839 29534377
Calciphylaxis 39.85 11.64 19 26292 993 29547223
Ventricular hyperkinesia 37.86 11.64 12 26299 203 29548013
Kidney transplant rejection 36.95 11.64 38 26273 6967 29541249
Right atrial enlargement 36.61 11.64 12 26299 227 29547989
Anion gap 35.80 11.64 16 26295 720 29547496
Completed suicide 35.45 11.64 18 26293 90228 29457988
Blood phosphorus increased 34.86 11.64 25 26286 2812 29545404
Renal cyst haemorrhage 33.98 11.64 13 26298 392 29547824
Protein urine present 33.34 11.64 30 26281 4664 29543552
Haemoglobin decreased 32.79 11.64 186 26125 108189 29440027
Blood potassium increased 31.64 11.64 51 26260 14600 29533616
Mitral valve thickening 31.39 11.64 12 26299 361 29547855
Rectal prolapse 31.27 11.64 11 26300 260 29547956
Arteriosclerotic gangrene 29.95 11.64 8 26303 71 29548145
Vena cava injury 29.62 11.64 10 26301 208 29548008
Unevaluable event 29.47 11.64 75 26236 29776 29518440
Mean platelet volume increased 29.44 11.64 12 26299 429 29547787
SARS-CoV-2 antibody test positive 28.97 11.64 10 26301 223 29547993
Intraductal papillary mucinous neoplasm 28.84 11.64 11 26300 329 29547887
Electrolyte imbalance 28.20 11.64 42 26269 11232 29536984
Congenital oesophageal anomaly 28.00 11.64 8 26303 93 29548123
Lymphangitis 27.25 11.64 12 26299 521 29547695
Bronchopneumopathy 26.79 11.64 11 26300 401 29547815
Electrocardiogram QRS complex prolonged 26.73 11.64 25 26286 4085 29544131
Labelled drug-drug interaction medication error 25.81 11.64 42 26269 12117 29536099
Complications of transplanted kidney 25.61 11.64 24 26287 3930 29544286
Hypokalaemia 25.32 11.64 100 26211 50103 29498113
Toxic epidermal necrolysis 24.98 11.64 52 26259 18101 29530115
Left ventricular enlargement 24.94 11.64 12 26299 640 29547576
Blood chloride increased 24.74 11.64 20 26291 2689 29545527
Posthaemorrhagic hydrocephalus 23.58 11.64 7 26304 94 29548122
Left atrial enlargement 23.30 11.64 12 26299 741 29547475
Drug clearance decreased 23.29 11.64 15 26296 1415 29546801
High density lipoprotein decreased 23.08 11.64 20 26291 2959 29545257
Anaemia 22.82 11.64 276 26035 200675 29347541
Acidosis 22.63 11.64 35 26276 9670 29538546
Hypocalcaemia 22.59 11.64 54 26257 20611 29527605
Chemotherapeutic drug level increased 22.24 11.64 8 26303 202 29548014
Morganella infection 22.15 11.64 10 26301 461 29547755
Bronchial haemorrhage 21.47 11.64 11 26300 672 29547544
Suicidal ideation 20.91 11.64 3 26308 34713 29513503
Withdrawal hypertension 20.28 11.64 7 26304 156 29548060
Left ventricular hypertrophy 19.75 11.64 27 26284 6676 29541540
Blood uric acid increased 19.73 11.64 25 26286 5743 29542473
Electrocardiogram T wave inversion 18.78 11.64 15 26296 1982 29546234
Spontaneous haemorrhage 18.75 11.64 7 26304 197 29548019
Porphyria acute 18.59 11.64 7 26304 202 29548014
Hypervolaemia 18.27 11.64 45 26266 17500 29530716
Burns second degree 18.07 11.64 8 26303 352 29547864
Acute respiratory distress syndrome 18.02 11.64 53 26258 22882 29525334
Eosinophil count increased 17.78 11.64 27 26284 7342 29540874
Hypoprothrombinaemia 17.73 11.64 8 26303 368 29547848
Burkholderia test positive 17.57 11.64 11 26300 988 29547228
Polyhydramnios 17.53 11.64 7 26304 237 29547979
Abdominal wall haemorrhage 17.21 11.64 7 26304 249 29547967
Retinopathy hypertensive 16.97 11.64 7 26304 258 29547958
Renal artery stenosis 16.90 11.64 14 26297 1947 29546269
Blood triglycerides increased 16.77 11.64 36 26275 12798 29535418
Hyperuricaemia 16.28 11.64 25 26286 6864 29541352
Carotid arteriosclerosis 16.14 11.64 12 26299 1426 29546790
Multiple epiphyseal dysplasia 16 11.64 3 26308 3 29548213
Aplasia pure red cell 16.00 11.64 22 26289 5469 29542747
Tumour lysis syndrome 15.96 11.64 37 26274 13847 29534369
Cardiac arrest 15.74 11.64 130 26181 85461 29462755
Bicytopenia 15.66 11.64 13 26298 1814 29546402
Procedural pain 15.48 11.64 19 26292 4225 29543991
Metabolic alkalosis 15.43 11.64 11 26300 1225 29546991
Bilirubin conjugated increased 15.25 11.64 16 26295 3001 29545215
Renal transplant 14.89 11.64 12 26299 1606 29546610
Sinusitis 14.80 11.64 6 26305 34344 29513872
Nephrogenic anaemia 14.72 11.64 13 26298 1972 29546244
Fluid balance positive 14.64 11.64 4 26307 39 29548177
Fall 14.60 11.64 95 26216 177083 29371133
Drug intolerance 14.49 11.64 13 26298 48366 29499850
Asthma 14.45 11.64 6 26305 33843 29514373
Myeloperoxidase deficiency 14.20 11.64 4 26307 44 29548172
Glomerular filtration rate decreased 14.03 11.64 31 26280 11235 29536981
Mean cell volume increased 14.03 11.64 14 26297 2475 29545741
Human anaplasmosis 13.96 11.64 4 26307 47 29548169
Vitamin D decreased 13.88 11.64 15 26296 2910 29545306
Osteitis 13.74 11.64 11 26300 1458 29546758
Rash 13.58 11.64 106 26205 189713 29358503
Stress 13.52 11.64 46 26265 21444 29526772
White blood cell count increased 13.09 11.64 67 26244 37449 29510767
Histology abnormal 13.04 11.64 6 26305 289 29547927
Renal disorder 13.04 11.64 47 26264 22548 29525668
Foetal exposure during pregnancy 12.92 11.64 7 26304 33860 29514356
Lip ulceration 12.84 11.64 8 26303 712 29547504
Serum ferritin increased 12.82 11.64 20 26291 5568 29542648
Hypotension 12.70 11.64 243 26068 194111 29354105
Therapeutic product effect incomplete 12.46 11.64 10 26301 39295 29508921
Hypernatraemia 12.39 11.64 23 26288 7363 29540853
Peritonitis bacterial 12.37 11.64 20 26291 5736 29542480
Fatigue 12.35 11.64 203 26108 316618 29231598
Urinary tract infection 12.30 11.64 108 26203 72246 29475970
Blood calcium decreased 12.28 11.64 26 26285 9156 29539060
Febrile neutropenia 12.20 11.64 153 26158 112087 29436129
Hypertensive heart disease 12.16 11.64 12 26299 2095 29546121
Blood pressure systolic decreased 12.11 11.64 16 26295 3828 29544388
Drug interaction 12.00 11.64 115 26196 197270 29350946
Off label use 11.97 11.64 192 26119 300608 29247608
Joint swelling 11.93 11.64 16 26295 49614 29498602
Vascular anastomotic haemorrhage 11.81 11.64 4 26307 84 29548132
Psoriasis 11.81 11.64 7 26304 32220 29515996
Oesophagitis 11.80 11.64 30 26281 11893 29536323
Nephrogenic systemic fibrosis 11.80 11.64 16 26295 3926 29544290
Focal segmental glomerulosclerosis 11.76 11.64 11 26300 1796 29546420
Product contamination physical 11.74 11.64 3 26308 22 29548194

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Acute kidney injury 284.19 11.01 793 41978 448447 64007514
Renal impairment 278.94 11.01 393 42378 134624 64321337
Renal failure 228.53 11.01 422 42349 181266 64274695
Metabolic acidosis 210.07 11.01 247 42524 70711 64385250
Blood creatinine increased 152.82 11.01 301 42470 135481 64320480
Hyperkalaemia 142.47 11.01 247 42524 100882 64355079
Renal injury 129.25 11.01 96 42675 15333 64440628
Metabolic alkalosis 127.73 11.01 59 42712 3869 64452092
Blood urea increased 124.51 11.01 150 42621 44003 64411958
Lymphocyte count decreased 104.65 11.01 132 42639 40567 64415394
Anhedonia 100.98 11.01 79 42692 13627 64442334
Fear 100.79 11.01 93 42678 20078 64435883
Incision site pain 89.86 11.01 41 42730 2613 64453348
Chronic kidney disease 86.17 11.01 145 42626 57774 64398187
Arthralgia 85.05 11.01 101 42670 442159 64013802
Drug intolerance 82.42 11.01 13 42758 187979 64267982
Multiple organ dysfunction syndrome 77.91 11.01 193 42578 101220 64354741
Hypokalaemia 75.38 11.01 214 42557 121689 64334272
Neutrophil count increased 73.38 11.01 87 42684 25087 64430874
Hypochromasia 72.55 11.01 24 42747 636 64455325
Anaemia 72.53 11.01 464 42307 378216 64077745
Rheumatoid arthritis 68.42 11.01 13 42758 164281 64291680
Electrocardiogram QRS complex prolonged 65.33 11.01 52 42719 9192 64446769
Acidosis 61.19 11.01 67 42704 17728 64438233
Joint swelling 60.17 11.01 34 42737 215348 64240613
Arthropathy 58.72 11.01 6 42765 120961 64335000
Delayed graft function 58.54 11.01 32 42739 3004 64452957
Kidney transplant rejection 57.79 11.01 49 42722 9462 64446499
Fatigue 57.25 11.01 279 42492 748451 63707510
Injury 56.81 11.01 119 42652 55873 64400088
Haemoglobin decreased 56.80 11.01 268 42503 194795 64261166
Alopecia 55.90 11.01 20 42751 165670 64290291
Hypotension 54.96 11.01 436 42335 380538 64075423
Drug clearance decreased 54.39 11.01 29 42742 2590 64453371
Red blood cells urine positive 54.33 11.01 35 42736 4443 64451518
Hypocalcaemia 52.36 11.01 97 42674 41656 64414305
Contraindicated product administered 50.69 11.01 6 42765 107823 64348138
Protein urine present 50.07 11.01 44 42727 8912 64447049
Blood phosphorus increased 48.80 11.01 34 42737 4912 64451049
Unevaluable event 48.56 11.01 105 42666 50384 64405577
Therapeutic product effect decreased 48.29 11.01 9 42762 115342 64340619
Rash 46.95 11.01 152 42619 458397 63997564
Sinusitis 46.91 11.01 19 42752 145909 64310052
Emotional distress 46.80 11.01 85 42686 35953 64420008
Cardiac arrest 46.54 11.01 214 42557 153850 64302111
Renal cyst haemorrhage 43.67 11.01 15 42756 447 64455514
Respiratory failure 42.28 11.01 215 42556 160968 64294993
Hyperparathyroidism secondary 40.66 11.01 23 42748 2307 64453654
Headache 39.96 11.01 198 42573 529269 63926692
Tumour lysis syndrome 39.17 11.01 56 42715 19384 64436577
Electrolyte imbalance 38.60 11.01 64 42707 25179 64430782
Blood potassium increased 38.57 11.01 65 42706 25915 64430046
Ventricular hyperkinesia 38.51 11.01 12 42759 261 64455700
Completed suicide 38.19 11.01 56 42715 224358 64231603
Anion gap 36.89 11.01 20 42751 1847 64454114
Musculoskeletal stiffness 36.52 11.01 18 42753 123188 64332773
Right atrial enlargement 36.10 11.01 12 42759 323 64455638
Crystal nephropathy 34.99 11.01 17 42754 1248 64454713
Bradycardia 34.79 11.01 163 42608 118056 64337905
Weight increased 34.60 11.01 55 42716 213293 64242668
Ventricular fibrillation 34.50 11.01 59 42712 23801 64432160
Lymphangitis 34.42 11.01 17 42754 1294 64454667
Mitral valve thickening 33.98 11.01 12 42759 389 64455572
Hypernatraemia 33.67 11.01 41 42730 12148 64443813
Suicidal ideation 33.08 11.01 3 42768 66539 64389422
Peritonitis bacterial 32.75 11.01 35 42736 9008 64446953
Lactic acidosis 32.42 11.01 102 42669 61308 64394653
Arteriosclerotic gangrene 32.08 11.01 8 42763 73 64455888
Blood uric acid increased 32.08 11.01 33 42738 8130 64447831
Vena cava injury 31.98 11.01 10 42761 220 64455741
Drug hypersensitivity 31.76 11.01 69 42702 237746 64218215
SARS-CoV-2 antibody test positive 31.20 11.01 10 42761 239 64455722
Infusion related reaction 31.06 11.01 38 42733 164429 64291532
Acute respiratory distress syndrome 30.83 11.01 75 42696 38860 64417101
Pain in extremity 30.60 11.01 101 42670 302984 64152977
Treatment failure 30.42 11.01 20 42751 116796 64339165
Blood chloride increased 29.70 11.01 25 42746 4778 64451183
Hyperchloraemia 29.65 11.01 14 42757 965 64454996
Hypervolaemia 29.52 11.01 73 42698 38212 64417749
Bronchopneumopathy 29.41 11.01 12 42759 581 64455380
Psoriasis 29.15 11.01 6 42765 71697 64384264
Product prescribing error 29.06 11.01 69 42702 35200 64420761
Hepatic enzyme increased 29.06 11.01 26 42745 129917 64326044
Toxic epidermal necrolysis 28.79 11.01 71 42700 37095 64418866
Febrile neutropenia 28.77 11.01 218 42553 187439 64268522
Unresponsive to stimuli 28.74 11.01 86 42685 50307 64405654
Calciphylaxis 28.61 11.01 21 42750 3291 64452670
End stage renal disease 28.56 11.01 35 42736 10440 64445521
Ventricular tachycardia 28.20 11.01 67 42704 34198 64421763
Septic shock 27.88 11.01 141 42630 105296 64350665
Left ventricular enlargement 27.76 11.01 12 42759 672 64455289
High density lipoprotein decreased 27.46 11.01 22 42749 3924 64452037
Glossodynia 27.17 11.01 5 42766 64691 64391270
Central nervous system injury 26.89 11.01 8 42763 148 64455813
Peripheral swelling 26.85 11.01 62 42709 209091 64246870
Shock 26.46 11.01 70 42701 38170 64417791
Wound 26.17 11.01 9 42762 76468 64379493
Hyperuricaemia 26.10 11.01 33 42738 10158 64445803
Intraductal papillary mucinous neoplasm 25.97 11.01 11 42760 586 64455375
Hypoalbuminaemia 25.94 11.01 44 42727 17630 64438331
Urine chloride decreased 25.75 11.01 7 42764 92 64455869
Fall 25.40 11.01 167 42604 416659 64039302
Cardiogenic shock 25.18 11.01 62 42709 32365 64423596
Blood triglycerides increased 25.13 11.01 45 42726 18821 64437140
Systemic lupus erythematosus 25.10 11.01 10 42761 77602 64378359
Platelet count decreased 24.68 11.01 193 42578 167518 64288443
Hypersensitivity 24.60 11.01 59 42712 196393 64259568
Nasopharyngitis 24.46 11.01 59 42712 196014 64259947
Swelling 24.40 11.01 43 42728 160175 64295786
Abdominal discomfort 24.25 11.01 53 42718 182269 64273692
Sepsis 24.08 11.01 246 42525 230095 64225866
White blood cell count increased 23.99 11.01 97 42674 65917 64390044
Discomfort 23.69 11.01 12 42759 80866 64375095
Mean platelet volume increased 23.67 11.01 12 42759 966 64454995
Splenic injury 23.27 11.01 8 42763 239 64455722
Complications of transplanted kidney 23.24 11.01 23 42748 5412 64450549
Hyperphosphataemia 23.14 11.01 20 42751 3961 64452000
Left atrial enlargement 23.06 11.01 12 42759 1020 64454941
Circulatory collapse 22.58 11.01 61 42710 33671 64422290
Anisocytosis 22.09 11.01 11 42760 852 64455109
Feeling abnormal 22.07 11.01 34 42737 133568 64322393
Nephrogenic anaemia 22.00 11.01 18 42753 3307 64452654
Thrombocytopenia 21.51 11.01 235 42536 223566 64232395
Renal tubular necrosis 21.27 11.01 46 42725 22064 64433897
Postresuscitation encephalopathy 21.10 11.01 5 42766 36 64455925
Serum ferritin increased 21.02 11.01 27 42744 8441 64447520
Osteoarthritis 20.75 11.01 8 42763 63328 64392633
Bicytopenia 20.66 11.01 18 42753 3604 64452357
Haemodialysis 20.56 11.01 39 42732 17038 64438923
Eosinophil count increased 20.54 11.01 35 42736 14077 64441884
Chemotherapeutic drug level increased 20.51 11.01 8 42763 344 64455617
Haemodynamic instability 20.41 11.01 36 42735 14876 64441085
Endometritis 20.31 11.01 10 42761 756 64455205
Enzyme induction 20.27 11.01 6 42765 109 64455852
Labelled drug-drug interaction medication error 20.20 11.01 45 42726 22017 64433944
Left ventricular hypertrophy 20.06 11.01 28 42743 9478 64446483
Nephrogenic systemic fibrosis 19.93 11.01 22 42749 5870 64450091
Cytomegalovirus infection 19.83 11.01 62 42709 37137 64418824
Tubulointerstitial nephritis 19.80 11.01 55 42716 30854 64425107
Injection site pain 19.73 11.01 27 42744 111381 64344580
Renal artery stenosis 19.49 11.01 16 42755 2953 64453008
Febrile bone marrow aplasia 19.21 11.01 30 42741 11225 64444736
Cardiovascular insufficiency 19.05 11.01 15 42756 2609 64453352
Multiple epiphyseal dysplasia 18.96 11.01 3 42768 0 64455961
Small for dates baby 18.80 11.01 8 42763 431 64455530
Injection site reaction 18.77 11.01 4 42767 46660 64409301
Urine sodium decreased 18.69 11.01 7 42764 269 64455692
Cardiac assistance device user 18.66 11.01 5 42766 62 64455899
Plasma cell myeloma 18.60 11.01 70 42701 46005 64409956
Insomnia 18.55 11.01 68 42703 197768 64258193
Bronchial haemorrhage 18.50 11.01 11 42760 1211 64454750
Aplasia pure red cell 18.42 11.01 23 42748 6991 64448970
Therapeutic product effect incomplete 18.40 11.01 25 42746 103457 64352504
Local anaesthetic systemic toxicity 18.33 11.01 9 42762 676 64455285
Gait disturbance 18.31 11.01 56 42715 172099 64283862
Morganella infection 17.74 11.01 10 42761 996 64454965
Carotid arteriosclerosis 17.55 11.01 13 42758 2066 64453895
Withdrawal hypertension 17.54 11.01 7 42764 320 64455641
Nephropathy toxic 17.49 11.01 37 42734 17477 64438484
Status epilepticus 17.43 11.01 42 42729 21621 64434340
Migraine 17.33 11.01 10 42761 62667 64393294
Blood albumin decreased 17.11 11.01 41 42730 21032 64434929
Urticaria 17.08 11.01 46 42725 147271 64308690
Asthma 16.94 11.01 23 42748 95202 64360759
Kidney fibrosis 16.87 11.01 15 42756 3086 64452875
Hypoglycaemia 16.42 11.01 109 42662 89783 64366178
Activated partial thromboplastin time prolonged 16.32 11.01 30 42741 12801 64443160
Vascular parkinsonism 16.30 11.01 5 42766 103 64455858
Leukopenia 16.28 11.01 119 42652 101123 64354838
Pruritus 16.19 11.01 131 42640 312269 64143692
Dialysis 16.04 11.01 35 42736 16885 64439076
Helicobacter infection 16.03 11.01 3 42768 38359 64417602
Pulmonary oedema 15.98 11.01 98 42673 78576 64377385
Bilirubin conjugated increased 15.86 11.01 18 42753 4950 64451011
Glomerular filtration rate decreased 15.81 11.01 38 42733 19534 64436427
Fluid balance positive 15.80 11.01 4 42767 39 64455922
Abdominal wall haemorrhage 15.77 11.01 7 42764 418 64455543
Mean cell volume increased 15.64 11.01 18 42753 5028 64450933
Diastolic dysfunction 15.62 11.01 24 42747 8851 64447110
Multiple sclerosis relapse 15.61 11.01 4 42767 41131 64414830
Spontaneous haemorrhage 15.60 11.01 7 42764 429 64455532
Focal segmental glomerulosclerosis 15.54 11.01 14 42757 2930 64453031
Diarrhoea 15.41 11.01 605 42166 722099 63733862
Oesophagitis 15.38 11.01 40 42731 21590 64434371
Thrombotic microangiopathy 15.28 11.01 34 42737 16621 64439340
Pulseless electrical activity 15.22 11.01 29 42742 12710 64443251
Retinopathy hypertensive 15.09 11.01 7 42764 463 64455498
Pleural effusion 15.09 11.01 139 42632 126420 64329541
Encephalopathy 15.08 11.01 78 42693 58741 64397220
Hypoprothrombinaemia 15.04 11.01 8 42763 711 64455250
Rectal prolapse 15.04 11.01 11 42760 1715 64454246
Product use issue 14.99 11.01 51 42720 151664 64304297
Injection site bruising 14.87 11.01 3 42768 36370 64419591
Osteonecrosis of jaw 14.87 11.01 4 42767 39821 64416140
Sulphaemoglobinaemia 14.81 11.01 3 42768 9 64455952
N-terminal prohormone brain natriuretic peptide 14.69 11.01 4 42767 53 64455908
General physical health deterioration 14.58 11.01 203 42568 204222 64251739
Proteinuria 14.58 11.01 46 42725 27677 64428284
Human anaplasmosis 14.55 11.01 4 42767 55 64455906
Haemodialysis complication 14.54 11.01 6 42765 299 64455662
Nasal congestion 14.49 11.01 11 42760 59647 64396314
Loss of personal independence in daily activities 14.47 11.01 16 42755 72438 64383523
Acute lung injury 14.44 11.01 13 42758 2718 64453243
Haemorrhage 14.36 11.01 96 42675 79255 64376706
Azotaemia 14.22 11.01 21 42750 7481 64448480
Drug level above therapeutic 14.08 11.01 20 42751 6881 64449080
Back pain 13.85 11.01 103 42668 250068 64205893
Drug level increased 13.84 11.01 52 42719 34144 64421817
Disseminated intravascular coagulation 13.77 11.01 50 42721 32298 64423663
Macrocytosis 13.61 11.01 12 42759 2440 64453521
Mental status changes 13.58 11.01 78 42693 61084 64394877
Procedural pain 13.50 11.01 31 42740 15477 64440484
Irritable bowel syndrome 13.49 11.01 4 42767 37365 64418596
Renal tubular acidosis 13.47 11.01 13 42758 2966 64452995
Blood magnesium decreased 13.46 11.01 29 42742 13876 64442085
Intestinal ischaemia 13.44 11.01 26 42745 11523 64444438
Nausea 13.42 11.01 408 42363 785392 63670569
Rhinorrhoea 13.40 11.01 12 42759 59957 64396004
Pericarditis 13.39 11.01 13 42758 62503 64393458
Leukocytosis 13.34 11.01 55 42716 37685 64418276
Sleep disorder 13.28 11.01 12 42759 59697 64396264
Hypoxia 13.26 11.01 102 42669 88047 64367914
Anion gap increased 13.23 11.01 13 42758 3031 64452930
Arthritis 13.20 11.01 22 42749 83792 64372169
Burns second degree 13.04 11.01 8 42763 932 64455029
Pneumonia 12.99 11.01 473 42298 559103 63896858
Red blood cell count decreased 12.99 11.01 65 42706 48321 64407640
Vascular anastomotic haemorrhage 12.97 11.01 4 42767 84 64455877
Hypoaesthesia 12.91 11.01 48 42723 139060 64316901
Perineal cyst 12.88 11.01 4 42767 86 64455875
Necrosis 12.87 11.01 21 42750 8150 64447811
Gastrointestinal disorder 12.83 11.01 25 42746 89684 64366277
Electrocardiogram T wave inversion 12.77 11.01 16 42755 4878 64451083
Cardio-respiratory arrest 12.72 11.01 110 42661 98283 64357678
Peritonitis 12.69 11.01 41 42730 24982 64430979
Rhabdomyolysis 12.63 11.01 104 42667 91622 64364339
Hyperaemia 12.59 11.01 12 42759 2697 64453264
Generalised tonic-clonic seizure 12.49 11.01 56 42715 39801 64416160
Renal transplant 12.48 11.01 11 42760 2237 64453724
Cytokine release syndrome 12.31 11.01 36 42735 20793 64435168
Dehydration 12.28 11.01 207 42564 216556 64239405
Porphyria acute 12.27 11.01 7 42764 713 64455248
Wrong technique in product usage process 12.27 11.01 15 42756 64959 64391002
Ill-defined disorder 12.22 11.01 7 42764 44045 64411916
Urinary tract infection pseudomonal 12.18 11.01 9 42762 1425 64454536
Complications of transplant surgery 12.11 11.01 7 42764 732 64455229
Renal disorder 12.08 11.01 51 42720 35314 64420647
Hypomagnesaemia 12.08 11.01 53 42718 37323 64418638
Malaise 11.88 11.01 188 42583 396059 64059902
Haemolysis 11.82 11.01 24 42747 11015 64444946
Cataract 11.76 11.01 10 42761 51252 64404709
Hepatic function abnormal 11.75 11.01 78 42693 64235 64391726
Renal lymphocele 11.72 11.01 4 42767 117 64455844
pH body fluid abnormal 11.56 11.01 4 42767 122 64455839
Myeloperoxidase deficiency 11.53 11.01 3 42768 33 64455928
Amyloidosis 11.50 11.01 11 42760 2483 64453478
Oliguria 11.45 11.01 28 42743 14548 64441413
Arrhythmia 11.42 11.01 67 42704 52877 64403084
Product monitoring error 11.41 11.01 16 42755 5438 64450523
Pyelonephritis 11.33 11.01 31 42740 17235 64438726
Aortic valve incompetence 11.31 11.01 20 42751 8281 64447680
Brain injury 11.07 11.01 22 42749 9943 64446018
Maternal exposure during pregnancy 11.06 11.01 30 42741 95854 64360107

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B05CB04 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
IRRIGATING SOLUTIONS
Salt solutions
ATC B05XA02 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
I.V. SOLUTION ADDITIVES
Electrolyte solutions
CHEBI has role CHEBI:65265 antacids
CHEBI has role CHEBI:77965 food anti-caking agent

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
5MG,N/A;N/A,210GM;N/A,0.74GM;N/A,2.86GM;N/A,5.6GM **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** HALFLYTELY BRAINTREE N021551 July 16, 2010 DISCN FOR SOLUTION, TABLET, DELAYED RELEASE ORAL 7291324 Oct. 22, 2022 GASTROINTESTINAL LAVAGE INDICATED FOR CLEANSING OF THE COLON AS A PREPARATION FOR COLONOSCOPY IN ADULTS
0.21GM/100ML;2.8GM/100ML;9.07GM/100ML NORMOCARB HF 25 DIALYSIS SUPS N021910 July 26, 2006 RX SOLUTION INJECTION 7300674 March 4, 2023 USE AS REPLACEMENT SOLUTION, HEMOFILTRATION SOLUTION OR HEMODIAFILTRATION SOLUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
3.68GM/1000ML;3.05GM/1000ML;0.314GM/1000ML ;3.09GM/1000ML;6.34GM/1000ML;0.187GM/1000ML (5000ML) PHOXILLUM BK 4/2.5 IN PLASTIC CONTAINER BAXTER HLTHCARE CORP N207026 Jan. 13, 2015 RX INJECTABLE INJECTION Jan. 13, 2022 AS A REPLACEMENT SOLUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY (CRRT) AND IN CASE OF DRUG POISONING WHEN CRRT IS USED TO REMOVE DIALYZABLE SUBSTANCES
N/A/1000ML;3.05GM/1000ML;0.314GM/1000ML;2.21GM/1000ML;6.95GM/1000ML;0.187GM/1000ML (5000ML) PHOXILLUM B22K 4/0 IN PLASTIC CONTAINER BAXTER HLTHCARE CORP N207026 Jan. 13, 2015 RX INJECTABLE INJECTION Jan. 13, 2022 AS A REPLACEMENT SOLUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY (CRRT) AND IN CASE OF DRUG POISONING WHEN CRRT IS USED TO REMOVE DIALYZABLE SUBSTANCES

Bioactivity Summary:

None

External reference:

IDSource
4018192 VUID
N0000146526 NUI
D01203 KEGG_DRUG
4018192 VANDF
C0074722 UMLSCUI
CHEBI:32139 CHEBI
CHEMBL1353 ChEMBL_ID
D017693 MESH_DESCRIPTOR_UI
DB01390 DRUGBANK_ID
8MDF5V39QO UNII
516892 PUBCHEM_CID
36676 RXNORM
1720 MMSL
5473 MMSL
d00440 MMSL
000743 NDDF
001116 NDDF
011039 NDDF
387319002 SNOMEDCT_US
57376006 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Good Sense Omeprazole and Sodium Bicarbonate HUMAN OTC DRUG LABEL 2 0113-0058 CAPSULE, GELATIN COATED 1100 mg ORAL ANDA 15 sections
Good Sense Omeprazole and Sodium Bicarbonate HUMAN OTC DRUG LABEL 2 0113-0058 CAPSULE, GELATIN COATED 1100 mg ORAL ANDA 15 sections
Alka-Seltzer Heartburn HUMAN OTC DRUG LABEL 2 0280-0047 TABLET, EFFERVESCENT 1940 mg ORAL OTC monograph final 17 sections
Alka-Seltzer Heartburn Relief Extra Strength HUMAN OTC DRUG LABEL 2 0280-0079 TABLET, EFFERVESCENT 1976 mg ORAL OTC monograph final 16 sections
Alka-Seltzer Heartburn Relief Lemon Lime HUMAN OTC DRUG LABEL 2 0280-0083 TABLET, EFFERVESCENT 1976 mg ORAL OTC monograph final 16 sections
Alka-Seltzer Heartburn Relief Lemon Lime HUMAN OTC DRUG LABEL 2 0280-0083 TABLET, EFFERVESCENT 1650 mg ORAL OTC monograph final 16 sections
Alka-Seltzer Extra Strength HUMAN OTC DRUG LABEL 3 0280-0211 GRANULE, EFFERVESCENT 1985 mg ORAL OTC monograph not final 17 sections
Alka-Seltzer Original HUMAN OTC DRUG LABEL 3 0280-4000 TABLET, EFFERVESCENT 1916 mg ORAL OTC monograph not final 17 sections
Alka-Seltzer Lemon Lime HUMAN OTC DRUG LABEL 3 0280-4020 TABLET, EFFERVESCENT 1700 mg ORAL OTC monograph not final 16 sections
Alka-Seltzer Gold HUMAN OTC DRUG LABEL 3 0280-4100 TABLET, EFFERVESCENT 1050 mg ORAL OTC monograph final 16 sections
CEO-TWO HUMAN OTC DRUG LABEL 2 0283-0808 SUPPOSITORY 618 mg RECTAL OTC monograph not final 15 sections
Walgreens Effervescent Pain Relief HUMAN OTC DRUG LABEL 3 0363-0421 TABLET, EFFERVESCENT 1916 mg ORAL OTC monograph final 17 sections
Walgreens Antacid Pain Relief Extra Strength HUMAN OTC DRUG LABEL 3 0363-0541 TABLET, EFFERVESCENT 1985 mg ORAL OTC monograph final 17 sections
Walgreens Antacid Pain Relief Extra Strength HUMAN OTC DRUG LABEL 3 0363-0541 TABLET, EFFERVESCENT 1985 mg ORAL OTC monograph final 17 sections
Omeprazole and sodium bicarbonate HUMAN OTC DRUG LABEL 2 0363-0732 CAPSULE, GELATIN COATED 1100 mg ORAL ANDA 15 sections
Omeprazole and sodium bicarbonate HUMAN OTC DRUG LABEL 2 0363-0732 CAPSULE, GELATIN COATED 1100 mg ORAL ANDA 15 sections
Well at Walgreens HUMAN OTC DRUG LABEL 2 0363-0801 POWDER, FOR SOLUTION 700 mg NASAL unapproved drug other 11 sections
Well at Walgreens HUMAN OTC DRUG LABEL 2 0363-0801 POWDER, FOR SOLUTION 700 mg NASAL unapproved drug other 11 sections
Well at Walgreens HUMAN OTC DRUG LABEL 2 0363-0802 POWDER, FOR SOLUTION 700 mg NASAL unapproved drug other 11 sections
Well at Walgreens HUMAN OTC DRUG LABEL 2 0363-0802 POWDER, FOR SOLUTION 700 mg NASAL unapproved drug other 11 sections
Humco Sodium Bicarbonate HUMAN OTC DRUG LABEL 1 0395-2685 POWDER 1000 mg ORAL OTC monograph final 10 sections
Humco Sodium Bicarbonate HUMAN OTC DRUG LABEL 1 0395-2685 POWDER 1000 mg ORAL OTC monograph final 10 sections
Sodium Bicarbonate HUMAN OTC DRUG LABEL 1 0395-9124 POWDER 1000 mg ORAL OTC monograph final 10 sections
Sodium Bicarbonate HUMAN PRESCRIPTION DRUG LABEL 1 0404-9948 INJECTION, SOLUTION 42 mg INTRAVENOUS unapproved drug other 11 sections
Sodium Bicarbonate HUMAN PRESCRIPTION DRUG LABEL 1 0404-9949 INJECTION, SOLUTION 75 mg INTRAVENOUS unapproved drug other 13 sections
SODIUM BICARBONATE HUMAN PRESCRIPTION DRUG LABEL 1 0404-9951 INJECTION, SOLUTION 42 mg INTRAVENOUS ANDA 11 sections
SODIUM BICARBONATE HUMAN PRESCRIPTION DRUG LABEL 1 0404-9951 INJECTION, SOLUTION 42 mg INTRAVENOUS ANDA 11 sections
Sodium Bicarbonate HUMAN PRESCRIPTION DRUG LABEL 1 0404-9980 INJECTION, SOLUTION 84 mg INTRAVENOUS unapproved drug other 12 sections
Sodium Bicarbonate HUMAN PRESCRIPTION DRUG LABEL 1 0409-4900 INJECTION, SOLUTION 84 mg INTRAVENOUS ANDA 12 sections
Sodium Bicarbonate HUMAN PRESCRIPTION DRUG LABEL 1 0409-4900 INJECTION, SOLUTION 84 mg INTRAVENOUS ANDA 12 sections