sodium chloride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4198 7647-14-5

Description:

MoleculeDescription

Synonyms:

  • sodium chloride
A ubiquitous sodium salt that is commonly used to season food.
  • Molecular weight: 58.44
  • Formula: ClNa
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

DoseUnitRoute
1 g O

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 16, 1965 FDA HOSPIRA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Myelosuppression 2609.76 10.41 1117 109828 22586 63355491
Agranulocytosis 923.40 10.41 565 110380 24569 63353508
Infective pulmonary exacerbation of cystic fibrosis 799.87 10.41 363 110582 8454 63369623
White blood cell count decreased 680.04 10.41 1014 109931 138090 63239987
Bone marrow failure 526.40 10.41 425 110520 28865 63349212
Hereditary angioedema 475.10 10.41 242 110703 7320 63370757
Drug intolerance 355.33 10.41 57 110888 308604 63069473
Neutrophil count decreased 332.45 10.41 450 110495 55956 63322121
Hyperchloraemia 324.51 10.41 98 110847 665 63377412
Contraindicated product administered 324.05 10.41 13 110932 217635 63160442
Joint swelling 304.39 10.41 97 110848 327569 63050508
Synovitis 301.20 10.41 5 110940 186913 63191164
Rheumatoid arthritis 298.60 10.41 44 110901 253775 63124302
Arthropathy 268.66 10.41 44 110901 234748 63143329
Drug ineffective 267.29 10.41 937 110008 1043828 62334249
Systemic lupus erythematosus 246.17 10.41 36 110909 208882 63169195
Chills 246.11 10.41 584 110361 112794 63265283
Therapeutic product effect decreased 242.82 10.41 27 110918 193160 63184917
Alopecia 240.87 10.41 146 110799 337390 63040687
Peritonitis bacterial 238.23 10.41 132 110813 4747 63373330
Treatment failure 237.55 10.41 33 110912 199010 63179067
Macular degeneration 222.91 10.41 243 110702 24133 63353944
Chest discomfort 216.90 10.41 546 110399 109423 63268654
Glossodynia 214.99 10.41 29 110916 178847 63199230
Cystic fibrosis 211.46 10.41 107 110838 3189 63374888
Hepatic function abnormal 203.29 10.41 286 110659 36856 63341221
Completed suicide 203.15 10.41 13 110932 145660 63232417
Pyrexia 182.01 10.41 1424 109521 469054 62909023
Pericarditis 168.86 10.41 17 110928 131562 63246515
Peritoneal dialysis complication 166.15 10.41 67 110878 1153 63376924
Arthralgia 158.64 10.41 491 110454 569219 62808858
Toxic anterior segment syndrome 151.43 10.41 70 110875 1701 63376376
Wound 148.47 10.41 50 110895 163213 63214864
Swelling 142.21 10.41 163 110782 275215 63102862
Musculoskeletal stiffness 141.42 10.41 73 110872 184545 63193532
Hyperpyrexia 136.76 10.41 83 110862 3549 63374528
Abdominal discomfort 133.56 10.41 222 110723 320663 63057414
Hepatic enzyme increased 125.05 10.41 102 110843 202226 63175851
Helicobacter infection 121.65 10.41 11 110934 92774 63285303
Drug hypersensitivity 121.07 10.41 224 110721 310463 63067614
Psoriatic arthropathy 119.58 10.41 11 110934 91509 63286568
Infusion site extravasation 118.85 10.41 117 110828 10309 63367768
Fungal peritonitis 115.41 10.41 41 110904 488 63377589
Toxicity to various agents 108.55 10.41 165 110780 247085 63130992
Sepsis 107.79 10.41 541 110404 152582 63225495
Hypernatraemia 107.11 10.41 96 110849 7513 63370564
Infusion site pain 106.10 10.41 139 110806 16730 63361347
Sinusitis 104.47 10.41 716 110229 225937 63152140
COVID-19 103.70 10.41 432 110513 112671 63265406
Leukopenia 102.74 10.41 333 110612 76957 63301120
Hyponatraemia 101.49 10.41 426 110519 111474 63266603
Incorrect drug administration rate 101.21 10.41 71 110874 3891 63374186
Peritonitis 99.69 10.41 136 110809 17018 63361059
Vomiting 96.92 10.41 1442 109503 558175 62819902
Hospitalisation 95.11 10.41 346 110599 84735 63293342
Granulocytopenia 94.92 10.41 79 110866 5593 63372484
Mobility decreased 92.61 10.41 48 110897 121111 63256966
Device interaction 91.96 10.41 28 110917 196 63377881
Temperature intolerance 90.13 10.41 94 110851 8870 63369207
Pain 88.18 10.41 849 110096 739779 62638298
Folliculitis 87.85 10.41 10 110935 70307 63307770
Sensitisation 78.05 10.41 57 110888 3329 63374748
Cytokine release syndrome 77.96 10.41 110 110835 14204 63363873
Product use issue 76.44 10.41 170 110775 220350 63157727
Discomfort 76.04 10.41 109 110836 167265 63210812
Tachypnoea 75.69 10.41 120 110825 17182 63360895
Flushing 75.33 10.41 295 110650 74792 63303285
Infusion site erythema 74.63 10.41 97 110848 11582 63366495
Insurance issue 74.10 10.41 71 110874 6050 63372027
Urinary tract infection 72.06 10.41 743 110202 263941 63114136
Infusion site coldness 71.91 10.41 23 110922 193 63377884
Infusion site swelling 71.77 10.41 87 110858 9683 63368394
Psoriasis 70.17 10.41 32 110913 86925 63291152
Osmotic demyelination syndrome 68.78 10.41 30 110915 633 63377444
Dyspnoea 68.13 10.41 1572 109373 659741 62718336
Hyponatraemic encephalopathy 68.07 10.41 23 110922 233 63377844
Irritable bowel syndrome 67.01 10.41 30 110915 82382 63295695
Pneumonia 66.87 10.41 1145 109800 455622 62922455
Nausea 66.27 10.41 1956 108989 852515 62525562
Polycystic ovaries 66.10 10.41 58 110887 4413 63373664
Pantoea agglomerans infection 64.87 10.41 15 110930 27 63378050
Granulocyte count decreased 64.54 10.41 35 110910 1205 63376872
Acidosis hyperchloraemic 63.37 10.41 25 110920 405 63377672
Blood pressure decreased 63.24 10.41 253 110692 64769 63313308
Drug interaction 63.15 10.41 198 110747 228933 63149144
Blister 62.53 10.41 81 110864 129733 63248344
Extravasation 61.74 10.41 43 110902 2329 63375748
Infusion site haemorrhage 61.58 10.41 59 110886 5027 63373050
Stomatitis 61.38 10.41 92 110853 138633 63239444
Paraesthesia oral 61.24 10.41 116 110829 19140 63358937
Death 60.50 10.41 954 109991 373427 63004650
Hypokalaemia 59.60 10.41 347 110598 103457 63274620
Gamma-glutamyltransferase decreased 59.35 10.41 22 110923 298 63377779
Illness 58.65 10.41 204 110741 48855 63329222
Poor venous access 58.51 10.41 98 110847 14687 63363390
Upper respiratory tract infection 58.46 10.41 291 110654 81756 63296321
Maternal exposure during pregnancy 57.98 10.41 194 110751 219868 63158209
Chronic sinusitis 57.46 10.41 90 110855 12753 63365324
Infusion related reaction 57.05 10.41 668 110277 244853 63133224
Cystic fibrosis respiratory infection suppression 56.96 10.41 21 110924 280 63377797
Ejection fraction 56.59 10.41 41 110904 2365 63375712
Condition aggravated 56.15 10.41 442 110503 401775 62976302
Abdominal distension 56.02 10.41 299 110646 86316 63291761
Pulmonary function test decreased 55.95 10.41 50 110895 3897 63374180
Procedural pain 55.54 10.41 119 110826 21450 63356627
Ejection fraction abnormal 55.18 10.41 36 110909 1749 63376328
Type 2 diabetes mellitus 53.92 10.41 22 110923 63846 63314231
Peripheral swelling 53.92 10.41 260 110685 265682 63112395
Therapeutic response decreased 53.91 10.41 20 110925 61505 63316572
Gadolinium deposition disease 52.11 10.41 15 110930 84 63377993
Knee arthroplasty 52.11 10.41 15 110930 54191 63323886
Ear infection 51.99 10.41 166 110779 38047 63340030
Endophthalmitis 51.91 10.41 46 110899 3546 63374531
C-reactive protein abnormal 51.85 10.41 9 110936 46087 63331990
Osteoarthritis 51.83 10.41 54 110891 95289 63282788
Infusion site induration 51.42 10.41 30 110915 1192 63376885
Pallor 51.27 10.41 143 110802 30425 63347652
Incorrect route of product administration 50.63 10.41 133 110812 27319 63350758
Blood cholesterol increased 50.28 10.41 54 110891 93978 63284099
Febrile neutropenia 49.71 10.41 366 110579 118083 63259994
Burkholderia cepacia complex infection 49.03 10.41 16 110929 144 63377933
Cardiac arrest 48.43 10.41 302 110643 92243 63285834
Ultrafiltration failure 48.34 10.41 17 110928 196 63377881
Respiratory tract infection 48.29 10.41 171 110774 41312 63336765
Intentional overdose 47.51 10.41 36 110909 74116 63303961
Sleep disorder due to general medical condition, insomnia type 47.42 10.41 16 110929 52201 63325876
Anaphylactic shock 47.21 10.41 118 110827 23515 63354562
Therapy non-responder 47.17 10.41 38 110907 75863 63302214
Cyanosis 46.59 10.41 96 110849 16839 63361238
Arthritis 46.48 10.41 82 110863 115839 63262238
Suspected transmission of an infectious agent via product 46.06 10.41 18 110927 284 63377793
Hypervolaemia 45.78 10.41 131 110814 28282 63349795
Device related infection 44.85 10.41 115 110830 23277 63354800
Seasonal allergy 44.39 10.41 107 110838 20843 63357234
Platelet count decreased 43.81 10.41 350 110595 115772 63262305
Encapsulating peritoneal sclerosis 43.49 10.41 18 110927 332 63377745
Drug abuse 42.99 10.41 38 110907 72480 63305597
Insomnia 42.71 10.41 212 110733 215040 63163037
Ill-defined disorder 42.55 10.41 48 110897 81707 63296370
Disturbance in social behaviour 42.18 10.41 43 110902 3950 63374127
Wound infection pseudomonas 41.58 10.41 27 110918 1301 63376776
Weight increased 41.46 10.41 276 110669 260516 63117561
Lymphatic fistula 40.40 10.41 22 110923 764 63377313
Suicide attempt 39.77 10.41 29 110916 60889 63317188
Headache 39.65 10.41 1414 109531 631827 62746250
Hip arthroplasty 39.27 10.41 17 110928 47629 63330448
Red blood cell sedimentation rate increased 39.03 10.41 14 110931 43968 63334109
Femoral hernia incarcerated 39.00 10.41 22 110923 819 63377258
Impaired healing 38.92 10.41 75 110870 102467 63275610
Cardiovascular disorder 38.61 10.41 72 110873 11740 63366337
Product contamination 38.31 10.41 21 110924 739 63377338
Product preparation error 38.00 10.41 50 110895 6042 63372035
Anterior chamber inflammation 37.89 10.41 16 110929 311 63377766
Myocardial reperfusion injury 37.38 10.41 12 110933 102 63377975
Unresponsive to stimuli 37.32 10.41 137 110808 33679 63344398
Blood sodium decreased 35.43 10.41 108 110837 24144 63353933
Pancreatic steatosis 35.15 10.41 22 110923 994 63377083
Cough 35.14 10.41 712 110233 292031 63086046
Inflammation 35.00 10.41 56 110889 82217 63295860
Hypersensitivity 34.85 10.41 335 110610 292350 63085727
Peritoneal cloudy effluent 34.63 10.41 12 110933 132 63377945
Depression 34.29 10.41 202 110743 196290 63181787
Maternal exposure during delivery 34.01 10.41 25 110920 1475 63376602
Lower respiratory tract infection 33.89 10.41 118 110827 132189 63245888
Fatigue 33.88 10.41 1241 109704 886787 62491290
Vein disorder 33.32 10.41 43 110902 5098 63372979
Disorganised speech 33.08 10.41 23 110922 1242 63376835
Bacteraemia 32.96 10.41 85 110860 17263 63360814
Suspected product quality issue 32.87 10.41 13 110932 212 63377865
Rhinitis allergic 32.87 10.41 67 110878 11660 63366417
Loss of personal independence in daily activities 32.86 10.41 76 110869 97214 63280863
Rash 32.42 10.41 740 110205 560131 62817946
Inappropriate schedule of product administration 32.21 10.41 300 110645 103665 63274412
Infusion site rash 31.77 10.41 27 110918 1967 63376110
Gait disturbance 31.60 10.41 189 110756 182989 63195088
Dehydration 31.11 10.41 450 110495 172904 63205173
Rapid correction of hyponatraemia 31.03 10.41 11 110934 130 63377947
Injury 31.03 10.41 50 110895 73197 63304880
Arterial haemorrhage 31.01 10.41 25 110920 1692 63376385
Post-traumatic neck syndrome 30.85 10.41 27 110918 2047 63376030
Cardiac disorder 30.54 10.41 172 110773 50644 63327433
Excessive eye blinking 30.53 10.41 22 110923 1258 63376819
Anaphylactoid reaction 30.40 10.41 35 110910 3688 63374389
Haemodialysis complication 29.78 10.41 12 110933 206 63377871
Post procedural complication 29.75 10.41 81 110864 16993 63361084
Infusion site bruising 29.58 10.41 35 110910 3797 63374280
Nephrectomy 29.47 10.41 23 110922 1485 63376592
Staphylococcal infection 29.14 10.41 146 110799 41110 63336967
Hypoxia 28.74 10.41 191 110754 59601 63318476
Pulmonary fibrosis 28.62 10.41 17 110928 39792 63338285
Vascular device infection 28.31 10.41 48 110897 7264 63370813
Haemoptysis 28.10 10.41 112 110833 28614 63349463
Pulmonary oedema 28.03 10.41 178 110767 54695 63323382
Bursitis 27.81 10.41 15 110930 37026 63341051
Gait inability 27.66 10.41 31 110914 52928 63325149
Product preparation issue 27.52 10.41 21 110924 1311 63376766
Osteoporosis 27.37 10.41 36 110909 57302 63320775
Epilepsy 26.86 10.41 106 110839 26959 63351118
Respiratory failure 26.74 10.41 284 110661 101574 63276503
Infusion site pruritus 26.59 10.41 42 110903 5993 63372084
Hepatorenal failure 26.49 10.41 16 110929 678 63377399
Product compounding quality issue 26.44 10.41 7 110938 27 63378050
Seroma 26.33 10.41 25 110920 2106 63375971
Acute pulmonary oedema 25.76 10.41 49 110896 8109 63369968
Neutropenic sepsis 25.71 10.41 75 110870 16363 63361714
Multiple allergies 25.58 10.41 67 110878 13735 63364342
Sleep disorder due to a general medical condition 25.55 10.41 62 110883 12126 63365951
Hypotension 25.47 10.41 640 110305 271964 63106113
Prescribed underdose 25.43 10.41 10 110935 29679 63348398
Productive cough 25.20 10.41 193 110752 63015 63315062
Discoloured vomit 25.14 10.41 17 110928 877 63377200
Burkholderia test positive 25.14 10.41 11 110934 234 63377843
Sputum increased 25.10 10.41 26 110919 2433 63375644
Infusion site mass 25.06 10.41 24 110921 2044 63376033
Intentional self-injury 24.89 10.41 7 110938 25680 63352397
Product deposit 24.84 10.41 11 110934 241 63377836
Cystic fibrosis lung 24.76 10.41 9 110936 115 63377962
Blood creatine increased 24.71 10.41 39 110906 5562 63372515
Anaphylactic reaction 24.25 10.41 198 110747 65902 63312175
Oxygen saturation decreased 24.20 10.41 249 110696 88336 63289741
General physical health deterioration 24.17 10.41 230 110715 201172 63176905
Memory impairment 24.08 10.41 97 110848 104161 63273916
Mental status changes postoperative 23.89 10.41 10 110935 190 63377887
Vasodilatation 23.87 10.41 25 110920 2370 63375707
Ovarian hyperstimulation syndrome 23.59 10.41 32 110913 3982 63374095
Joint stiffness 23.56 10.41 23 110922 41846 63336231
Blood test abnormal 23.20 10.41 70 110875 15559 63362518
Joint range of motion decreased 23.10 10.41 14 110931 32414 63345663
Pain in extremity 23.07 10.41 424 110521 331062 63047015
Poor quality product administered 23.01 10.41 28 110917 3128 63374949
Cold sweat 22.86 10.41 59 110886 11988 63366089
Suspected product contamination 22.49 10.41 6 110939 24 63378053
Peripheral coldness 22.49 10.41 59 110886 12106 63365971
Obstetric procedure complication 22.39 10.41 5 110940 7 63378070
Laryngospasm 22.30 10.41 27 110918 3001 63375076
Nephrocalcinosis 22.28 10.41 17 110928 1061 63377016
Cytopenia 22.21 10.41 57 110888 11544 63366533
Sleep disorder 22.08 10.41 71 110874 81495 63296582
Oliguria 22.05 10.41 49 110896 9052 63369025
Back pain 22.03 10.41 611 110334 263534 63114543
Injection site reaction 22.03 10.41 43 110902 58481 63319596
Bloody peritoneal effluent 21.96 10.41 7 110938 58 63378019
Confusion postoperative 21.90 10.41 10 110935 236 63377841
Pseudomonas infection 21.37 10.41 55 110890 11158 63366919
Osteonecrosis of jaw 21.31 10.41 18 110927 35105 63342972
Femur fracture 21.20 10.41 25 110920 41731 63336346
Necrotic lymphadenopathy 21.16 10.41 7 110938 66 63378011
Burning sensation 21.06 10.41 165 110780 54242 63323835
Electrolyte imbalance 21.04 10.41 80 110865 19996 63358081
Acute respiratory failure 20.90 10.41 117 110828 34368 63343709
Suicidal ideation 20.88 10.41 49 110896 62372 63315705
Cognitive disorder 20.16 10.41 42 110903 55773 63322304
Procedural complication 20.13 10.41 35 110910 5404 63372673
Dysphoria 19.76 10.41 33 110912 4933 63373144
Gastroenteritis viral 19.75 10.41 88 110857 23612 63354465
Disability 19.74 10.41 4 110941 18343 63359734
Drug reaction with eosinophilia and systemic symptoms 19.73 10.41 18 110927 33818 63344259
Blood creatinine decreased 19.64 10.41 35 110910 5510 63372567
C-reactive protein increased 19.50 10.41 92 110853 94615 63283462
Administration site extravasation 19.47 10.41 15 110930 950 63377127
Musculoskeletal pain 19.38 10.41 89 110856 92188 63285889
Confusional state 19.16 10.41 294 110651 236086 63141991
Extradural haematoma 19.02 10.41 19 110926 1703 63376374
Vaginal flatulence 18.97 10.41 26 110919 3267 63374810
Hepatitis 18.97 10.41 25 110920 39763 63338314
Sinus operation 18.95 10.41 23 110922 2563 63375514
Aortic valve stenosis 18.93 10.41 26 110919 3273 63374804
Dry mouth 18.90 10.41 71 110874 77792 63300285
Liver disorder 18.89 10.41 41 110904 53646 63324431
Balance disorder 18.59 10.41 80 110865 84342 63293735
Ventricular fibrillation 18.42 10.41 54 110891 11813 63366264
Haemarthrosis 18.27 10.41 25 110920 3136 63374941
Catheter site pain 18.22 10.41 31 110914 4704 63373373
Air embolism 18.17 10.41 9 110936 256 63377821
Pharyngitis streptococcal 17.97 10.41 50 110895 10622 63367455
Hepatotoxicity 17.94 10.41 23 110922 37018 63341059
Eye infection 17.66 10.41 54 110891 12091 63365986
Overdose 17.66 10.41 123 110822 114955 63263122
Laryngeal oedema 17.63 10.41 34 110911 5684 63372393
Adverse event 17.46 10.41 60 110885 67499 63310578
Wound dehiscence 17.44 10.41 31 110914 4872 63373205
Vascular compression 17.32 10.41 8 110937 194 63377883
Pulse abnormal 17.28 10.41 21 110924 2343 63375734
Marasmus 17.24 10.41 11 110934 514 63377563
Diverticulum intestinal 17.24 10.41 37 110908 6676 63371401
Gastrointestinal infection 17.15 10.41 45 110900 9236 63368841
Haemodilution 17.07 10.41 7 110938 126 63377951
Product administration error 17.06 10.41 81 110864 22316 63355761
Tachyarrhythmia 16.95 10.41 29 110916 4421 63373656
Brain death 16.81 10.41 25 110920 3385 63374692
Moaning 16.74 10.41 13 110932 833 63377244
Cataract operation complication 16.72 10.41 7 110938 133 63377944
Product contamination microbial 16.70 10.41 8 110937 211 63377866
Infusion site thrombosis 16.67 10.41 7 110938 134 63377943
Hepatocellular injury 16.65 10.41 14 110931 27367 63350710
Rhinovirus infection 16.58 10.41 29 110916 4500 63373577
Carpal tunnel syndrome 16.38 10.41 76 110869 20741 63357336
Device infusion issue 16.37 10.41 19 110926 2019 63376058
Erythema 16.21 10.41 412 110533 175339 63202738
Gastrointestinal disorder 16.11 10.41 149 110796 131090 63246987
Infusion site discomfort 16.06 10.41 16 110929 1430 63376647
Tachycardia 16.06 10.41 293 110652 117863 63260214
Pneumorrhachis 16.05 10.41 3 110942 0 63378077
Product barcode issue 16.05 10.41 3 110942 0 63378077
Lethargy 16.04 10.41 159 110786 55848 63322229
Cardiogenic shock 16.03 10.41 68 110877 17864 63360213
Amnesia 16.03 10.41 47 110898 55538 63322539
Sciatica 15.92 10.41 22 110923 34302 63343775
Haemolysis 15.90 10.41 36 110909 6732 63371345
Metabolic alkalosis 15.90 10.41 23 110922 3038 63375039
Sinus tachycardia 15.83 10.41 84 110861 24184 63353893
Infective exacerbation of bronchiectasis 15.74 10.41 9 110936 344 63377733
Central venous catheterisation 15.70 10.41 21 110924 2578 63375499
Inappropriate antidiuretic hormone secretion 15.70 10.41 61 110884 15401 63362676
Corneal oedema 15.63 10.41 16 110929 1477 63376600
Product selection error 15.51 10.41 6 110939 92 63377985
Hypercholesterolaemia 15.49 10.41 9 110936 21325 63356752
Hypoaesthesia oral 15.40 10.41 54 110891 12979 63365098
Anaesthetic complication 15.29 10.41 18 110927 1942 63376135
Meningitis aseptic 15.27 10.41 29 110916 4794 63373283
Leukostasis syndrome 15.13 10.41 5 110940 47 63378030
Migraine 15.01 10.41 259 110686 103087 63274990
Feeling hot 14.94 10.41 144 110801 50210 63327867
Lip erosion 14.92 10.41 13 110932 980 63377097
Catheter site infection 14.88 10.41 29 110916 4885 63373192
Foot deformity 14.88 10.41 16 110929 27837 63350240
Septic shock 14.87 10.41 180 110765 66449 63311628
Stenotrophomonas test positive 14.80 10.41 4 110941 17 63378060
Immune effector cell-associated neurotoxicity syndrome 14.69 10.41 19 110926 2258 63375819
Metabolic acidosis 14.43 10.41 131 110814 44938 63333139
Fibromyalgia 14.37 10.41 82 110863 80338 63297739
Product substitution issue 14.35 10.41 5 110940 15991 63362086
Bronchitis 14.34 10.41 302 110643 124633 63253444
Distal intestinal obstruction syndrome 14.33 10.41 9 110936 409 63377668
Viral infection 14.27 10.41 109 110836 35554 63342523
Blood pressure fluctuation 14.21 10.41 38 110907 46279 63331798
Gastrostomy tube site complication 14.11 10.41 5 110940 59 63378018
Lung transplant 14.10 10.41 22 110923 3106 63374971
Apallic syndrome 14.10 10.41 11 110934 710 63377367
Diabetes insipidus 14.04 10.41 20 110925 2605 63375472
Pneumothorax 14.02 10.41 61 110884 16200 63361877
Fungal sepsis 14.01 10.41 14 110931 1256 63376821
Eructation 13.99 10.41 39 110906 8294 63369783
Perineal cellulitis 13.98 10.41 3 110942 3 63378074
Anterior chamber disorder 13.92 10.41 6 110939 123 63377954
Infusion site irritation 13.62 10.41 12 110933 918 63377159
COVID-19 pneumonia 13.58 10.41 55 110890 14154 63363923
Exposure via contaminated device 13.52 10.41 3 110942 4 63378073
Muscle spasticity 13.43 10.41 11 110934 21783 63356294
Failure to thrive 13.40 10.41 35 110910 7163 63370914
Eosinophilia 13.39 10.41 12 110933 22744 63355333
Live birth 13.38 10.41 15 110930 25615 63352462
Urticaria 13.38 10.41 382 110563 165420 63212657
Decreased appetite 13.34 10.41 551 110394 250501 63127576
Device difficult to use 13.34 10.41 3 110942 12793 63365284
Hypochloraemia 13.33 10.41 17 110928 1992 63376085
Haematuria 13.32 10.41 92 110853 29065 63349012
Female genital tract fistula 13.31 10.41 36 110909 7523 63370554
COVID-19 immunisation 13.27 10.41 16 110929 1771 63376306
Product container issue 13.22 10.41 16 110929 1777 63376300
Fracture 13.20 10.41 9 110936 19575 63358502
Retinal detachment 13.20 10.41 31 110914 5938 63372139
Mental disorder 13.18 10.41 84 110861 25835 63352242
Hypothyroidism 13.18 10.41 123 110822 42509 63335568
Hypoalbuminaemia 13.17 10.41 48 110897 11757 63366320
Immunisation reaction 13.17 10.41 10 110935 620 63377457
Disseminated intravascular coagulation 13.16 10.41 67 110878 18984 63359093
Creatinine renal clearance decreased 13.15 10.41 6 110939 16302 63361775
Seizure 13.15 10.41 314 110631 132320 63245757
Feeling cold 13.14 10.41 79 110866 23809 63354268
Tracheitis 13.01 10.41 11 110934 796 63377281
Normal newborn 12.99 10.41 38 110907 8303 63369774
Neonatal infection 12.93 10.41 6 110939 147 63377930
Infusion site phlebitis 12.91 10.41 5 110940 77 63378000
Coordination abnormal 12.89 10.41 4 110941 13769 63364308
Steatorrhoea 12.88 10.41 9 110936 490 63377587
Catheter site extravasation 12.87 10.41 8 110937 357 63377720
Proctitis 12.85 10.41 29 110916 5412 63372665
Abdominal pain upper 12.85 10.41 269 110676 206175 63171902
Injection site pain 12.83 10.41 155 110790 129645 63248432
Interstitial lung disease 12.82 10.41 60 110885 61848 63316229
Acidosis 12.81 10.41 46 110899 11187 63366890
Bacterial sepsis 12.78 10.41 24 110921 3934 63374143
Hepatic cyst 12.77 10.41 28 110917 5126 63372951
Renal disorder 12.76 10.41 100 110845 32874 63345203
Wrong product administered 12.62 10.41 31 110914 6110 63371967
Breast cancer female 12.58 10.41 4 110941 13555 63364522
Ileus 12.51 10.41 55 110890 14670 63363407
Blood fibrinogen decreased 12.48 10.41 11 110934 842 63377235
Infusion site discolouration 12.43 10.41 11 110934 846 63377231
Lymphocyte count decreased 12.40 10.41 93 110852 30164 63347913
Kidney infection 12.34 10.41 76 110869 23100 63354977
Pelvic fluid collection 12.22 10.41 11 110934 865 63377212
Faecaloma 12.20 10.41 36 110909 7905 63370172
Sleep apnoea syndrome 12.20 10.41 90 110855 29043 63349034
Obesity 12.17 10.41 21 110924 29931 63348146
Abortion spontaneous 12.14 10.41 42 110903 47153 63330924
Mental status changes 12.12 10.41 114 110831 39485 63338592
Product availability issue 12.09 10.41 24 110921 4097 63373980
Eyelid oedema 12.02 10.41 43 110902 10436 63367641
Musculoskeletal disorder 12.01 10.41 11 110934 20633 63357444
Local anaesthetic systemic toxicity 11.98 10.41 11 110934 888 63377189
Pancreatitis chronic 11.94 10.41 18 110927 2466 63375611
Pseudohyperphosphataemia 11.91 10.41 3 110942 9 63378068
Hyperkalaemia 11.90 10.41 146 110799 54057 63324020
Multiple sclerosis relapse 11.90 10.41 44 110901 48434 63329643
Impaired work ability 11.82 10.41 8 110937 17467 63360610
Pneumonia pseudomonal 11.68 10.41 18 110927 2515 63375562
Blood pressure systolic increased 11.64 10.41 43 110902 47354 63330723
Body temperature abnormal 11.58 10.41 16 110929 2025 63376052
Quadriplegia 11.58 10.41 15 110930 1785 63376292
Respiratory distress 11.54 10.41 100 110845 33851 63344226
Corneal disorder 11.49 10.41 15 110930 1799 63376278
Muscle discomfort 11.47 10.41 6 110939 192 63377885
Drug-induced liver injury 11.43 10.41 114 110831 40108 63337969
Obstruction 11.42 10.41 20 110925 3107 63374970
Muscular weakness 11.38 10.41 148 110797 122205 63255872
Hepatic cirrhosis 11.33 10.41 16 110929 24718 63353359
Drainage 11.30 10.41 6 110939 198 63377879
Amylase abnormal 11.25 10.41 3 110942 12 63378065
Blood glucose false positive 11.25 10.41 3 110942 12 63378065
Agitation 11.05 10.41 156 110789 59601 63318476
Paranoia 10.99 10.41 45 110900 11634 63366443
Influenza 10.96 10.41 258 110687 108464 63269613
Therapeutic response unexpected 10.91 10.41 10 110935 18749 63359328
Pulse absent 10.91 10.41 27 110918 5347 63372730
Blood chloride increased 10.90 10.41 18 110927 2666 63375411
Ulcer 10.89 10.41 18 110927 26089 63351988
Convulsions local 10.88 10.41 3 110942 14 63378063
Bone density decreased 10.85 10.41 6 110939 14606 63363471
Catheterisation venous 10.71 10.41 3 110942 15 63378062
Nail bed infection bacterial 10.71 10.41 3 110942 15 63378062
Vascular parkinsonism 10.61 10.41 5 110940 127 63377950
Aspartate aminotransferase increased 10.61 10.41 219 110726 90058 63288019
Pleural effusion 10.59 10.41 225 110720 92985 63285092
Mean cell haemoglobin decreased 10.49 10.41 26 110919 5153 63372924
Oral candidiasis 10.46 10.41 72 110873 22726 63355351
Intentional product misuse 10.41 10.41 63 110882 60854 63317223

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Myelosuppression 770.87 10.51 494 75067 18771 34862599
Infective pulmonary exacerbation of cystic fibrosis 696.52 10.51 325 75236 6476 34874894
Hyperchloraemia 412.25 10.51 113 75448 393 34880977
Peritonitis bacterial 354.23 10.51 199 75362 5911 34875459
Peritoneal dialysis complication 240.22 10.51 102 75459 1607 34879763
Cystic fibrosis 194.11 10.51 87 75474 1571 34879799
Drug ineffective 186.44 10.51 449 75112 456302 34425068
Fungal peritonitis 170.21 10.51 64 75497 719 34880651
Peritonitis 168.31 10.51 192 75369 16173 34865197
Completed suicide 163.15 10.51 13 75548 98155 34783215
Pyrexia 150.56 10.51 1230 74331 331783 34549587
Drug abuse 147.03 10.51 20 75541 99076 34782294
Toxicity to various agents 146.06 10.51 131 75430 200231 34681139
Toxic anterior segment syndrome 145.39 10.51 64 75497 1105 34880265
Drug interaction 139.66 10.51 170 75391 225776 34655594
Chills 134.46 10.51 433 75128 80610 34800760
Cytokine release syndrome 127.68 10.51 199 75362 22678 34858692
Hereditary angioedema 122.76 10.51 55 75506 992 34880378
Temperature intolerance 106.16 10.51 75 75486 3347 34878023
Sputum increased 105.29 10.51 65 75496 2305 34879065
Sinusitis 102.74 10.51 256 75305 41146 34840224
Bone marrow failure 99.49 10.51 205 75356 29048 34852322
Infusion site extravasation 94.44 10.51 77 75484 4267 34877103
Infusion related reaction 91.15 10.51 287 75274 52770 34828600
Osmotic demyelination syndrome 91.05 10.51 42 75519 813 34880557
White blood cell count decreased 90.24 10.51 427 75134 95018 34786352
Pneumonia 86.35 10.51 1177 74384 361450 34519920
Incorrect drug administration rate 84.08 10.51 50 75511 1655 34879715
Chest discomfort 82.92 10.51 283 75278 54247 34827123
Neutrophil count decreased 77.51 10.51 265 75296 50839 34830531
Flushing 72.70 10.51 193 75368 32227 34849143
Air embolism 72.15 10.51 22 75539 121 34881249
Arthralgia 69.87 10.51 166 75395 169875 34711495
Device interaction 69.60 10.51 31 75530 551 34880819
Hypernatraemia 66.77 10.51 87 75474 8403 34872967
Tachypnoea 66.42 10.51 132 75429 18220 34863150
Ultrafiltration failure 65.20 10.51 21 75540 142 34881228
Hyperpyrexia 61.83 10.51 50 75511 2738 34878632
Administration site extravasation 59.10 10.51 28 75533 577 34880793
Sepsis 57.40 10.51 581 74980 165980 34715390
Infusion site pain 55.31 10.51 54 75507 3797 34877573
Rapid correction of hyponatraemia 54.93 10.51 17 75544 99 34881271
Encapsulating peritoneal sclerosis 53.71 10.51 26 75535 563 34880807
Product preparation error 52.33 10.51 42 75519 2275 34879095
Increased bronchial secretion 51.00 10.51 38 75523 1843 34879527
Death 50.97 10.51 1171 74390 396878 34484492
Pulmonary function test decreased 50.51 10.51 58 75503 4917 34876453
Upper respiratory tract infection 49.73 10.51 171 75390 32888 34848482
Cystic fibrosis respiratory infection suppression 49.55 10.51 19 75542 226 34881144
Epilepsy 49.24 10.51 129 75432 21366 34860004
Psoriasis 48.59 10.51 12 75549 38800 34842570
Rheumatoid arthritis 47.53 10.51 12 75549 38226 34843144
Hepatic function abnormal 47.49 10.51 206 75355 44157 34837213
Spinal muscular atrophy 47.06 10.51 21 75540 375 34880995
Disease complication 46.26 10.51 42 75519 2694 34878676
Granulocyte count decreased 45.75 10.51 26 75535 789 34880581
Depression 45.49 10.51 88 75473 97010 34784360
Cough 44.84 10.51 509 75052 149631 34731739
Noninfectious peritonitis 44.61 10.51 15 75546 118 34881252
Peritoneal cloudy effluent 44.48 10.51 16 75545 157 34881213
Extravasation 44.27 10.51 35 75526 1855 34879515
Dysphoria 44.24 10.51 38 75523 2264 34879106
Device infusion issue 43.76 10.51 26 75535 859 34880511
Intentional overdose 43.40 10.51 20 75541 43654 34837716
Anaphylactic shock 43.18 10.51 102 75459 15839 34865531
Pneumococcal sepsis 42.59 10.51 28 75533 1109 34880261
Eosinophil count 42.27 10.51 15 75546 141 34881229
Joint swelling 41.37 10.51 41 75520 59849 34821521
Hypervolaemia 40.85 10.51 114 75447 19595 34861775
Disorganised speech 40.66 10.51 25 75536 880 34880490
Therapeutic product effect incomplete 40.52 10.51 30 75531 50511 34830859
Oxygen saturation decreased 40.50 10.51 226 75335 53592 34827778
Product contamination 40.44 10.51 23 75538 699 34880671
Suicide attempt 40.31 10.51 17 75544 39099 34842271
Vocal cord dysfunction 40.01 10.51 15 75546 167 34881203
Hypoxia 39.90 10.51 229 75332 54866 34826504
Acidosis hyperchloraemic 38.73 10.51 19 75542 424 34880946
Cardiac arrest 38.31 10.51 346 75215 95813 34785557
Infusion site oedema 37.05 10.51 15 75546 208 34881162
Disease progression 36.50 10.51 116 75445 107961 34773409
Therapeutic product effect decreased 35.96 10.51 15 75546 34728 34846642
COVID-19 35.59 10.51 288 75273 77262 34804108
Drug intolerance 35.46 10.51 46 75515 59524 34821846
Cyanosis 34.93 10.51 82 75479 12682 34868688
Febrile neutropenia 33.92 10.51 448 75113 136401 34744969
Insurance issue 33.88 10.51 31 75530 2008 34879362
Product preparation issue 33.80 10.51 17 75544 401 34880969
Respiratory tract infection 33.24 10.51 106 75455 19606 34861764
Burkholderia test positive 33.08 10.51 23 75538 1000 34880370
Hospitalisation 32.75 10.51 223 75338 56679 34824691
Drug resistance 32.48 10.51 8 75553 25919 34855451
Hypokalaemia 32.24 10.51 226 75335 57988 34823382
Treatment failure 32.21 10.51 32 75529 46665 34834705
Productive cough 31.99 10.51 164 75397 37649 34843721
Infusion site swelling 31.86 10.51 33 75528 2491 34878879
Drug dependence 31.28 10.51 7 75554 24210 34857160
Lower respiratory tract infection bacterial 30.90 10.51 17 75544 484 34880886
Stoma closure 30.63 10.51 14 75547 265 34881105
Overdose 30.55 10.51 98 75463 90961 34790409
Motor neurone disease 30.40 10.51 17 75544 500 34880870
Drug reaction with eosinophilia and systemic symptoms 29.99 10.51 17 75544 32995 34848375
Musculoskeletal stiffness 29.95 10.51 34 75527 46646 34834724
Suspected transmission of an infectious agent via product 29.63 10.51 20 75541 828 34880542
Myalgia 29.29 10.51 89 75472 84021 34797349
Lymphadenectomy 29.14 10.51 15 75546 372 34880998
Immune effector cell-associated neurotoxicity syndrome 29.12 10.51 38 75523 3675 34877695
Product contamination microbial 29.06 10.51 18 75543 642 34880728
Pantoea agglomerans infection 29.00 10.51 9 75552 53 34881317
Erectile dysfunction 28.68 10.51 5 75556 20632 34860738
Device related infection 28.44 10.51 92 75469 17145 34864225
Gait disturbance 28.30 10.51 92 75469 85048 34796322
Endotracheal intubation 28.24 10.51 34 75527 3031 34878339
Suffocation feeling 28.15 10.51 17 75544 579 34880791
Unresponsive to stimuli 27.97 10.51 126 75435 27443 34853927
Bloody peritoneal effluent 27.37 10.51 10 75551 103 34881267
Gangrene 27.13 10.51 41 75520 4545 34876825
Weight decreased 27.10 10.51 247 75314 176054 34705316
Coronary artery disease 27.04 10.51 39 75522 48266 34833104
Ischaemic cerebral infarction 26.89 10.51 22 75539 1225 34880145
Hyponatraemia 26.78 10.51 285 75276 82406 34798964
Suspected product contamination 26.74 10.51 9 75552 71 34881299
Pain in extremity 26.73 10.51 162 75399 126351 34755019
Pancreatic enzyme abnormality 26.63 10.51 9 75552 72 34881298
Angioedema 26.48 10.51 25 75536 37349 34844021
Suicidal ideation 26.36 10.51 29 75532 40359 34841011
Respiratory failure 26.29 10.51 354 75207 108218 34773152
Vomiting 25.77 10.51 709 74852 246912 34634458
Infusion site erythema 25.65 10.51 28 75533 2245 34879125
Peritoneal effluent abnormal 25.37 10.51 8 75553 50 34881320
Intentional product misuse 25.35 10.51 37 75524 45574 34835796
Dyspnoea 25.20 10.51 1024 74537 375758 34505612
Complication associated with device 25.18 10.51 46 75515 5960 34875410
Transurethral resection syndrome 24.61 10.51 6 75555 11 34881359
Endophthalmitis 24.60 10.51 34 75527 3474 34877896
Prostate cancer 24.23 10.51 30 75531 39619 34841751
Resuscitation 23.97 10.51 22 75539 1431 34879939
Cataract operation complication 23.64 10.51 10 75551 156 34881214
Toxic epidermal necrolysis 23.53 10.51 101 75460 21545 34859825
Heart rate increased 23.40 10.51 176 75385 46167 34835203
Eye infection 23.40 10.51 34 75527 3639 34877731
Tumour lysis syndrome 22.88 10.51 85 75476 16974 34864396
Catheter site infection 22.61 10.51 28 75533 2569 34878801
Fungal sepsis 22.42 10.51 17 75544 847 34880523
Poor quality product administered 22.41 10.51 24 75537 1883 34879487
Delirium 22.18 10.51 167 75394 43824 34837546
Therapeutic response decreased 21.49 10.51 19 75542 29294 34852076
Hypotension 21.48 10.51 629 74932 221020 34660350
Contraindicated product administered 21.09 10.51 10 75551 21471 34859899
Arthritis 21.02 10.51 22 75539 31324 34850046
Bronchial disorder 20.76 10.51 20 75541 1383 34879987
Pneumonia aspiration 20.52 10.51 158 75403 41745 34839625
Gadolinium deposition disease 20.49 10.51 6 75555 28 34881342
Foetal exposure during pregnancy 20.12 10.51 32 75529 38069 34843301
Metabolic disorder 19.49 10.51 34 75527 4249 34877121
Illness 19.49 10.51 69 75492 13460 34867910
Acute respiratory failure 19.48 10.51 124 75437 30804 34850566
Cystic fibrosis related diabetes 19.38 10.51 9 75552 177 34881193
Infective exacerbation of bronchiectasis 19.35 10.51 12 75549 429 34880941
Eosinophilia 19.22 10.51 17 75544 26205 34855165
Fluid imbalance 19.17 10.51 10 75551 255 34881115
Psychotic disorder 18.97 10.51 15 75546 24437 34856933
Leukoplakia oral 18.91 10.51 7 75554 75 34881295
Diabetes insipidus 18.50 10.51 27 75534 2901 34878469
Respiratory tract infection bacterial 18.47 10.51 21 75540 1761 34879609
Staphylococcal infection 18.02 10.51 127 75434 32633 34848737
Blood glucose false positive 17.76 10.51 6 75555 48 34881322
Product deposit 17.64 10.51 11 75550 397 34880973
COVID-19 pneumonia 17.55 10.51 78 75483 16889 34864481
Dysbiosis 17.46 10.51 12 75549 512 34880858
Suspected product quality issue 17.33 10.51 8 75553 155 34881215
Infusion site rash 17.23 10.51 12 75549 523 34880847
Pancreatic failure 17.04 10.51 14 75547 784 34880586
Procedural complication 16.95 10.51 32 75529 4251 34877119
Rhinovirus infection 16.87 10.51 32 75529 4267 34877103
Cardiac failure congestive 16.86 10.51 108 75453 83162 34798208
Hyponatraemic encephalopathy 16.85 10.51 6 75555 57 34881313
Respiration abnormal 16.84 10.51 27 75534 3149 34878221
Product distribution issue 16.83 10.51 13 75548 666 34880704
Arthropathy 16.82 10.51 20 75541 26887 34854483
Bronchial obstruction 16.67 10.51 19 75542 1597 34879773
Product prescribing error 16.64 10.51 15 75546 22912 34858458
Neuroleptic malignant syndrome 16.63 10.51 9 75552 17925 34863445
Hepatorenal failure 16.62 10.51 12 75549 554 34880816
Blood pressure fluctuation 16.62 10.51 18 75543 25231 34856139
Disturbance in attention 16.53 10.51 19 75542 25926 34855444
Sinus operation 16.52 10.51 13 75548 684 34880686
Influenza 16.46 10.51 172 75389 49494 34831876
Panic reaction 16.35 10.51 18 75543 1457 34879913
Failure to thrive 16.13 10.51 48 75513 8553 34872817
Chemical peritonitis 15.95 10.51 7 75554 120 34881250
Myelodysplastic syndrome 15.91 10.51 11 75550 19197 34862173
Body temperature increased 15.87 10.51 77 75484 17291 34864079
Intentional self-injury 15.85 10.51 5 75556 13766 34867604
Cholestasis 15.83 10.51 21 75540 26927 34854443
Blood pressure systolic increased 15.51 10.51 16 75545 22936 34858434
Benign prostatic hyperplasia 15.42 10.51 6 75555 14489 34866881
Extravasation of urine 15.42 10.51 3 75558 0 34881370
Blood bilirubin increased 15.33 10.51 138 75423 38158 34843212
Seasonal allergy 15.22 10.51 40 75521 6635 34874735
Aggression 15.21 10.51 39 75522 38925 34842445
Hypercalcaemia 15.17 10.51 70 75491 15398 34865972
Intestinal ischaemia 15.09 10.51 44 75517 7750 34873620
Lung consolidation 15.02 10.51 37 75524 5899 34875471
Vascular device infection 15.02 10.51 30 75531 4155 34877215
Respiratory syncytial virus infection 14.84 10.51 32 75529 4677 34876693
Blood sodium increased 14.81 10.51 24 75537 2824 34878546
Vocal cord paralysis 14.73 10.51 14 75547 952 34880418
Loss of personal independence in daily activities 14.73 10.51 31 75530 33148 34848222
Brain herniation 14.70 10.51 29 75532 3979 34877391
Product administration error 14.60 10.51 72 75489 16272 34865098
Gastroenteritis viral 14.55 10.51 41 75520 7083 34874287
Serotonin syndrome 14.52 10.51 13 75548 19920 34861450
Hepatocellular injury 14.44 10.51 16 75545 22195 34859175
Blood pressure decreased 14.16 10.51 172 75389 51343 34830027
Peritoneal effluent leukocyte count increased 14.15 10.51 4 75557 16 34881354
Staphylococcus test positive 14.12 10.51 25 75536 3161 34878209
Insomnia 14.08 10.51 150 75411 103757 34777613
Sputum retention 14.04 10.51 10 75551 452 34880918
Limb mass 13.98 10.51 12 75549 714 34880656
Demyelination 13.92 10.51 25 75536 3196 34878174
Platelet count decreased 13.92 10.51 348 75213 119369 34762001
Visual impairment 13.85 10.51 36 75525 35766 34845604
Post procedural complication 13.84 10.51 55 75506 11333 34870037
Scoliosis 13.80 10.51 23 75538 2770 34878600
Paraesthesia 13.63 10.51 82 75479 64090 34817280
Weight increased 13.56 10.51 132 75429 92901 34788469
Complication of device removal 13.47 10.51 5 75556 54 34881316
Urine analysis abnormal 13.45 10.51 19 75542 1982 34879388
Disease recurrence 13.41 10.51 16 75545 21474 34859896
Cardiovascular disorder 13.39 10.51 50 75511 10006 34871364
Nasopharyngitis 13.35 10.51 219 75342 69749 34811621
Rhegmatogenous retinal detachment 13.31 10.51 5 75556 56 34881314
Infection 13.30 10.51 273 75288 90642 34790728
Procedural pain 13.28 10.51 31 75530 4775 34876595
Lung transplant 13.28 10.51 19 75542 2005 34879365
Lower respiratory tract infection 13.17 10.51 115 75446 31522 34849848
Incision site pain 13.17 10.51 18 75543 1820 34879550
Anti-thyroid antibody positive 13.08 10.51 5 75556 59 34881311
Cystic fibrosis lung 13.08 10.51 5 75556 59 34881311
Atelectasis 13.03 10.51 74 75487 17653 34863717
Rectal haemorrhage 13.02 10.51 44 75517 40205 34841165
Haematochezia 13.01 10.51 54 75507 46480 34834890
Bacteraemia 13.01 10.51 80 75481 19637 34861733
Anaesthetic complication 12.99 10.51 14 75547 1106 34880264
Hypoaldosteronism 12.99 10.51 7 75554 191 34881179
Disseminated Bacillus Calmette-Guerin infection 12.92 10.51 7 75554 193 34881177
Chest X-ray abnormal 12.85 10.51 29 75532 4369 34877001
Tracheostomy malfunction 12.85 10.51 5 75556 62 34881308
Balance disorder 12.77 10.51 45 75516 40609 34840761
Regurgitation 12.72 10.51 17 75544 1682 34879688
Inappropriate antidiuretic hormone secretion 12.72 10.51 58 75503 12695 34868675
Bronchial hyperreactivity 12.65 10.51 17 75544 1692 34879678
Dyskinesia 12.63 10.51 18 75543 22395 34858975
Melaena 12.62 10.51 37 75524 35343 34846027
Brain oedema 12.43 10.51 61 75500 13760 34867610
Muscle spasms 12.42 10.51 103 75458 74898 34806472
Therapeutic response unexpected 12.24 10.51 3 75558 9754 34871616
Respiratory tract congestion 12.22 10.51 35 75526 6104 34875266
Hepatic cyst ruptured 12.13 10.51 3 75558 6 34881364
Diabetes mellitus 12.13 10.51 56 75505 46817 34834553
Peritoneal fluid analysis abnormal 12.06 10.51 4 75557 30 34881340
Dizziness 12.06 10.51 370 75191 218151 34663219
Off label use 12.03 10.51 764 74797 418760 34462610
Serratia infection 11.87 10.51 12 75549 880 34880490
Therapy non-responder 11.85 10.51 44 75517 39102 34842268
Lactobacillus test positive 11.84 10.51 4 75557 32 34881338
Injection site extravasation 11.67 10.51 22 75539 2920 34878450
Blood phosphorus decreased 11.65 10.51 23 75538 3158 34878212
Carbon dioxide increased 11.65 10.51 13 75548 1068 34880302
Multiple sclerosis relapse 11.59 10.51 7 75554 13126 34868244
Oropharyngeal discomfort 11.57 10.51 23 75538 3173 34878197
Blood albumin decreased 11.57 10.51 59 75502 13513 34867857
Moraxella infection 11.52 10.51 7 75554 241 34881129
Osteonecrosis of jaw 11.50 10.51 13 75548 17876 34863494
Bronchitis 11.49 10.51 140 75421 41823 34839547
Condition aggravated 11.46 10.51 322 75239 191874 34689496
Sopor 11.38 10.51 6 75555 12130 34869240
Systemic immune activation 11.33 10.51 4 75557 37 34881333
Respiratory acidosis 11.25 10.51 30 75531 5020 34876350
Dyspnoea paroxysmal nocturnal 11.23 10.51 15 75546 1484 34879886
Secretion discharge 11.11 10.51 33 75528 5872 34875498
Renal failure 11.09 10.51 207 75354 130350 34751020
Urine output decreased 11.00 10.51 47 75514 10002 34871368
Cognitive disorder 10.98 10.51 29 75532 28664 34852706
Basal cell carcinoma 10.87 10.51 16 75545 19642 34861728
Catheter site extravasation 10.83 10.51 5 75556 97 34881273
Fasciotomy 10.82 10.51 3 75558 11 34881359
Duplicate therapy error 10.77 10.51 6 75555 175 34881195
Decubitus ulcer 10.77 10.51 43 75518 8878 34872492
Sedation 10.76 10.51 18 75543 20988 34860382
Exposure during pregnancy 10.73 10.51 3 75558 8931 34872439
Alanine aminotransferase increased 10.63 10.51 239 75322 80576 34800794
Lactic acidosis 10.58 10.51 39 75522 34733 34846637
Labelled drug-drug interaction medication error 10.57 10.51 10 75551 14929 34866441
Peripheral swelling 10.57 10.51 110 75451 76431 34804939
Peritoneal disorder 10.54 10.51 7 75554 282 34881088

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Myelosuppression 3305.35 9.86 1585 149597 38711 79554495
Infective pulmonary exacerbation of cystic fibrosis 1264.95 9.86 574 150608 12277 79580929
White blood cell count decreased 849.21 9.86 1382 149800 186906 79406300
Agranulocytosis 675.83 9.86 610 150572 44420 79548786
Bone marrow failure 608.25 9.86 609 150573 50498 79542708
Peritonitis bacterial 440.01 9.86 256 150926 9311 79583895
Neutrophil count decreased 432.92 9.86 697 150485 93262 79499944
Completed suicide 374.39 9.86 23 151159 245744 79347462
Cystic fibrosis 358.78 9.86 166 151016 3714 79589492
Chills 344.99 9.86 865 150317 159369 79433837
Drug ineffective 336.90 9.86 998 150184 1079915 78513291
Pyrexia 304.02 9.86 2262 148920 676447 78916759
Hereditary angioedema 289.23 9.86 159 151023 5176 79588030
Drug intolerance 285.84 9.86 74 151108 264045 79329161
Joint swelling 281.34 9.86 98 151084 288548 79304658
Synovitis 269.36 9.86 3 151179 150731 79442475
Chest discomfort 263.99 9.86 713 150469 137331 79455875
Rheumatoid arthritis 259.48 9.86 42 151140 208428 79384778
Toxic anterior segment syndrome 254.78 9.86 118 151064 2646 79590560
Hepatic function abnormal 252.76 9.86 478 150704 72629 79520577
Toxicity to various agents 243.71 9.86 264 150918 421276 79171930
Contraindicated product administered 222.17 9.86 21 151161 157517 79435689
Peritoneal dialysis complication 221.67 9.86 102 151080 2252 79590954
Temperature intolerance 217.62 9.86 166 151016 9539 79583667
Cytokine release syndrome 206.72 9.86 296 150886 35702 79557504
Therapeutic product effect decreased 206.18 9.86 32 151150 163831 79429375
Arthralgia 204.54 9.86 492 150690 571311 79021895
Arthropathy 198.61 9.86 46 151136 177065 79416141
Hyperpyrexia 184.30 9.86 125 151057 5967 79587239
Drug interaction 175.35 9.86 325 150857 414858 79178348
Treatment failure 172.83 9.86 54 151128 170432 79422774
Fungal peritonitis 157.23 9.86 64 151118 1036 79592170
Drug abuse 157.10 9.86 56 151126 162635 79430571
Hypernatraemia 156.93 9.86 164 151018 14287 79578919
Osmotic demyelination syndrome 156.52 9.86 70 151112 1443 79591763
Alopecia 146.02 9.86 134 151048 231221 79361985
Peritonitis 145.75 9.86 220 150962 27816 79565390
Systemic lupus erythematosus 142.89 9.86 28 151154 121121 79472085
Tachypnoea 142.31 9.86 234 150948 31829 79561377
Flushing 137.75 9.86 424 150758 87844 79505362
Musculoskeletal stiffness 133.98 9.86 83 151099 174925 79418281
Sepsis 125.10 9.86 907 150275 268521 79324685
Psoriatic arthropathy 122.71 9.86 6 151176 77993 79515213
Infusion site extravasation 121.18 9.86 121 151061 9987 79583219
Device interaction 118.84 9.86 47 151135 703 79592503
Sputum increased 112.54 9.86 83 151099 4530 79588676
Granulocyte count decreased 112.33 9.86 59 151123 1749 79591457
Vomiting 111.88 9.86 1827 149355 664001 78929205
Glossodynia 111.60 9.86 29 151153 103308 79489898
Hyponatraemia 110.22 9.86 644 150538 177204 79416002
Pericarditis 109.28 9.86 31 151151 104205 79489001
Leukopenia 109.02 9.86 474 150708 116039 79477167
Febrile neutropenia 101.70 9.86 768 150414 230231 79362975
Pneumonia 100.45 9.86 1783 149399 658463 78934743
Infusion site pain 98.69 9.86 128 151054 14048 79579158
Anaphylactic shock 97.75 9.86 213 150969 35783 79557423
Helicobacter infection 93.85 9.86 11 151171 69693 79523513
Mobility decreased 92.04 9.86 59 151123 122116 79471090
Acidosis hyperchloraemic 90.45 9.86 40 151142 802 79592404
Hospitalisation 90.16 9.86 386 150796 93850 79499356
Psoriasis 87.90 9.86 30 151152 89557 79503649
Pantoea agglomerans infection 87.10 9.86 23 151159 79 79593127
Administration site extravasation 86.80 9.86 45 151137 1298 79591908
Incorrect drug administration rate 86.19 9.86 67 151115 3959 79589247
Wound 84.95 9.86 58 151124 116121 79477085
Unresponsive to stimuli 84.26 9.86 265 150917 55523 79537683
Hypokalaemia 83.73 9.86 513 150669 143527 79449679
Epilepsy 83.03 9.86 216 150966 40644 79552562
Dyspnoea 81.35 9.86 2162 149020 854863 78738343
Swelling 80.83 9.86 182 151000 216529 79376677
Dysphoria 80.73 9.86 69 151113 4665 79588541
Platelet count decreased 79.99 9.86 637 150545 194027 79399179
Drug hypersensitivity 79.35 9.86 295 150887 298621 79294585
Hyponatraemic encephalopathy 78.25 9.86 28 151154 312 79592894
Cyanosis 77.68 9.86 157 151025 25025 79568181
Pain 76.24 9.86 911 150271 702891 78890315
Intentional overdose 74.71 9.86 55 151127 105905 79487301
Granulocytopenia 74.61 9.86 100 151082 11331 79581875
Encapsulating peritoneal sclerosis 74.31 9.86 35 151147 816 79592390
Endophthalmitis 73.49 9.86 75 151107 6353 79586853
Gadolinium deposition disease 73.08 9.86 21 151161 106 79593100
Infusion site swelling 73.04 9.86 82 151100 7744 79585462
Extravasation 72.97 9.86 59 151123 3691 79589515
Suspected transmission of an infectious agent via product 71.69 9.86 38 151144 1148 79592058
Cystic fibrosis respiratory infection suppression 70.97 9.86 28 151154 416 79592790
Cardiac arrest 70.61 9.86 563 150619 171533 79421673
Weight increased 70.23 9.86 279 150903 277107 79316099
Pulmonary function test decreased 69.54 9.86 79 151103 7558 79585648
Product contamination 69.53 9.86 38 151144 1222 79591984
Hypoxia 67.95 9.86 380 150802 102863 79490343
Infusion site coldness 67.78 9.86 23 151159 216 79592990
Infusion site erythema 66.77 9.86 86 151096 9374 79583832
C-reactive protein abnormal 66.71 9.86 7 151175 48360 79544846
Sensitisation 66.35 9.86 53 151129 3258 79589948
Disorganised speech 65.38 9.86 44 151138 2073 79591133
Depression 64.95 9.86 203 150979 216587 79376619
Polycystic ovaries 64.27 9.86 55 151127 3724 79589482
Abdominal discomfort 64.22 9.86 251 150931 250476 79342730
Blood pressure decreased 63.41 9.86 363 150819 99103 79494103
Peripheral swelling 61.60 9.86 282 150900 269335 79323871
Product preparation error 61.57 9.86 65 151117 5728 79587478
Arthritis 60.80 9.86 77 151105 114803 79478403
Folliculitis 58.92 9.86 16 151166 55364 79537842
Rapid correction of hyponatraemia 58.89 9.86 19 151163 150 79593056
COVID-19 58.87 9.86 505 150677 157169 79436037
Suicide attempt 58.52 9.86 43 151139 82889 79510317
Irritable bowel syndrome 57.42 9.86 23 151159 62218 79530988
Condition aggravated 55.19 9.86 646 150536 500478 79092728
Therapeutic response decreased 55.00 9.86 29 151153 66824 79526382
Infusion site haemorrhage 54.99 9.86 50 151132 3670 79589536
Respiratory failure 54.77 9.86 554 150628 180357 79412849
Ultrafiltration failure 54.41 9.86 20 151162 242 79592964
Nausea 54.24 9.86 2273 148909 954923 78638283
Suspected product quality issue 54.23 9.86 21 151161 296 79592910
Infusion site induration 53.85 9.86 31 151151 1104 79592102
Incorrect route of product administration 53.73 9.86 167 151015 34762 79558444
Gamma-glutamyltransferase decreased 53.72 9.86 22 151160 362 79592844
Disease complication 53.55 9.86 56 151126 4881 79588325
Spinal muscular atrophy 52.69 9.86 22 151160 381 79592825
Product preparation issue 52.61 9.86 33 151149 1377 79591829
Hypervolaemia 52.27 9.86 189 150993 42501 79550705
Osteoarthritis 52.21 9.86 53 151129 87256 79505950
Paraesthesia oral 52.05 9.86 118 151064 20353 79572853
Oxygen saturation decreased 51.19 9.86 419 150763 128628 79464578
Infusion related reaction 49.55 9.86 660 150522 229577 79363629
Hepatic enzyme increased 49.22 9.86 179 151003 182431 79410775
Ejection fraction 49.09 9.86 38 151144 2231 79590975
Chronic sinusitis 48.53 9.86 88 151094 12938 79580268
Pain in extremity 47.80 9.86 451 150731 364087 79229119
Air embolism 47.26 9.86 21 151161 426 79592780
Drug reaction with eosinophilia and systemic symptoms 47.05 9.86 32 151150 64212 79528994
Pallor 47.05 9.86 204 150978 49858 79543348
Insurance issue 46.69 9.86 56 151126 5677 79587529
Device related infection 46.46 9.86 157 151025 34137 79559069
Peritoneal cloudy effluent 45.99 9.86 19 151163 320 79592886
Suspected product contamination 45.88 9.86 14 151168 90 79593116
Eosinophil count 45.58 9.86 15 151167 127 79593079
Procedural pain 44.83 9.86 120 151062 22964 79570242
Poor quality product administered 44.37 9.86 44 151138 3601 79589605
Gait disturbance 43.34 9.86 224 150958 207282 79385924
Overdose 43.05 9.86 191 150991 184015 79409191
Hepatorenal failure 42.81 9.86 28 151154 1257 79591949
Ejection fraction abnormal 42.50 9.86 36 151146 2404 79590802
Fatigue 41.77 9.86 1395 149787 928332 78664874
Knee arthroplasty 41.53 9.86 15 151167 43233 79549973
Insomnia 41.50 9.86 283 150899 244887 79348319
Cataract operation complication 41.27 9.86 17 151165 284 79592922
Macular degeneration 40.43 9.86 75 151107 11221 79581985
Abdominal distension 40.42 9.86 375 150807 119275 79473931
Sleep disorder due to general medical condition, insomnia type 40.33 9.86 16 151166 43540 79549666
Product contamination microbial 40.05 9.86 24 151158 922 79592284
Type 2 diabetes mellitus 39.81 9.86 30 151152 57092 79536114
Intentional self-injury 39.26 9.86 7 151175 32412 79560794
Wound infection pseudomonas 39.17 9.86 29 151153 1592 79591614
Pneumococcal sepsis 38.52 9.86 29 151153 1633 79591573
Increased bronchial secretion 38.36 9.86 39 151143 3288 79589918
Lymphatic fistula 38.28 9.86 22 151160 781 79592425
Sopor 38.14 9.86 8 151174 33002 79560204
Device infusion issue 37.83 9.86 33 151149 2293 79590913
Acute respiratory failure 37.74 9.86 217 150965 59324 79533882
Stomatitis 37.50 9.86 147 151035 146610 79446596
Therapy non-responder 37.34 9.86 74 151108 92231 79500975
Femoral hernia incarcerated 37.31 9.86 22 151160 820 79592386
Osteoporosis 36.97 9.86 29 151153 54083 79539123
Myocardial reperfusion injury 36.42 9.86 12 151170 102 79593104
Immune effector cell-associated neurotoxicity syndrome 36.41 9.86 50 151132 5798 79587408
Blister 36.38 9.86 111 151071 119365 79473841
Ill-defined disorder 36.06 9.86 43 151139 65832 79527374
Anaesthetic complication 35.71 9.86 35 151147 2824 79590382
Upper respiratory tract infection 35.60 9.86 295 150887 90873 79502333
Suicidal ideation 35.58 9.86 56 151126 76284 79516922
Cough 35.07 9.86 927 150255 365862 79227344
Bacteraemia 34.96 9.86 139 151043 32685 79560521
Red blood cell sedimentation rate increased 34.84 9.86 22 151160 45920 79547286
Diabetes insipidus 34.46 9.86 46 151136 5191 79588015
Balance disorder 34.46 9.86 86 151096 98771 79494435
Loss of personal independence in daily activities 34.40 9.86 91 151091 102489 79490717
Cytopenia 33.74 9.86 100 151082 20283 79572923
Drug resistance 33.72 9.86 19 151163 42194 79551012
Tumour lysis syndrome 33.67 9.86 111 151071 23828 79569378
Haemodialysis complication 33.64 9.86 15 151167 307 79592899
Noninfectious peritonitis 33.50 9.86 14 151168 243 79592963
Inappropriate antidiuretic hormone secretion 33.49 9.86 118 151064 26195 79567011
Vascular device infection 32.81 9.86 65 151117 10211 79582995
Gait inability 32.74 9.86 38 151144 58879 79534327
Pulmonary oedema 32.57 9.86 282 150900 87972 79505234
Hypotension 32.36 9.86 1077 150105 439240 79153966
Maternal exposure during delivery 32.34 9.86 24 151158 1322 79591884
Blood cholesterol increased 32.27 9.86 69 151113 83651 79509555
Discomfort 31.98 9.86 126 151056 125491 79467715
Blood glucose false positive 31.73 9.86 9 151173 43 79593163
Blood pressure systolic increased 31.35 9.86 49 151133 66937 79526269
Infective exacerbation of bronchiectasis 31.13 9.86 19 151163 755 79592451
Pancreatic steatosis 31.12 9.86 22 151160 1123 79592083
Memory impairment 31.11 9.86 108 151074 111626 79481580
Stoma closure 31.02 9.86 14 151168 295 79592911
Disturbance in social behaviour 30.20 9.86 42 151140 4928 79588278
Hip arthroplasty 30.17 9.86 15 151167 35741 79557465
Motor neurone disease 29.90 9.86 17 151165 591 79592615
Pulmonary fibrosis 29.68 9.86 24 151158 44088 79549118
Blood pressure fluctuation 29.67 9.86 51 151131 67094 79526112
Anaphylactic reaction 29.57 9.86 265 150917 83478 79509728
Bursitis 28.82 9.86 16 151166 35828 79557378
Anaphylactoid reaction 28.82 9.86 43 151139 5379 79587827
Rhinovirus infection 28.71 9.86 53 151129 7900 79585306
Toxic epidermal necrolysis 28.59 9.86 163 151019 44418 79548788
Product use issue 28.59 9.86 257 150925 209565 79383641
Illness 28.49 9.86 168 151014 46343 79546863
Infusion site oedema 28.44 9.86 19 151163 884 79592322
Electrolyte imbalance 28.37 9.86 125 151057 30756 79562450
Cognitive disorder 28.33 9.86 56 151126 69870 79523336
Staphylococcal infection 28.00 9.86 198 150984 58097 79535109
Burkholderia test positive 27.82 9.86 16 151166 569 79592637
Injection site pain 27.76 9.86 139 151043 129699 79463507
Impaired healing 27.72 9.86 80 151102 87575 79505631
Eosinophilia 27.71 9.86 27 151155 45318 79547888
Failure to thrive 27.62 9.86 66 151116 11778 79581428
Bloody peritoneal effluent 27.55 9.86 11 151171 169 79593037
Poisoning 27.45 9.86 7 151175 25265 79567941
Hepatocellular injury 27.21 9.86 30 151152 47563 79545643
Intentional product misuse 27.16 9.86 91 151091 95074 79498132
Musculoskeletal pain 27.12 9.86 101 151081 102253 79490953
Product administration error 27.09 9.86 126 151056 31720 79561486
Vocal cord dysfunction 27.07 9.86 16 151166 599 79592607
Post-traumatic neck syndrome 26.84 9.86 26 151156 2068 79591138
Injection site reaction 26.68 9.86 39 151143 54746 79538460
Sciatica 26.47 9.86 15 151167 33207 79559999
Poor venous access 26.29 9.86 85 151097 18064 79575142
Sinus operation 26.25 9.86 28 151154 2497 79590709
Osteonecrosis of jaw 26.11 9.86 26 151156 43200 79550006
Rhinitis allergic 26.10 9.86 66 151116 12203 79581003
Endotracheal intubation 26.05 9.86 38 151144 4659 79588547
Femur fracture 26.04 9.86 21 151161 38631 79554575
Arterial haemorrhage 25.92 9.86 28 151154 2533 79590673
Myalgia 25.89 9.86 226 150956 185415 79407791
Necrotic lymphadenopathy 25.84 9.86 9 151173 92 79593114
General physical health deterioration 25.73 9.86 367 150815 274871 79318335
Resuscitation 25.59 9.86 27 151155 2377 79590829
Respiratory tract infection 25.54 9.86 169 151013 48520 79544686
Productive cough 25.52 9.86 268 150914 88063 79505143
Product deposit 25.27 9.86 15 151167 566 79592640
Suffocation feeling 25.19 9.86 23 151159 1697 79591509
Inflammation 25.18 9.86 92 151090 93661 79499545
Haemodilution 25.14 9.86 10 151172 152 79593054
Seizure 25.11 9.86 500 150682 188334 79404872
Delirium 25.03 9.86 258 150924 84369 79508837
Urticaria 24.83 9.86 491 150691 184710 79408496
Lymphocyte count decreased 24.72 9.86 164 151018 47125 79546081
Blood bilirubin increased 24.63 9.86 212 150970 66020 79527186
Herpes zoster 24.57 9.86 92 151090 92991 79500215
Ovarian hyperstimulation syndrome 24.48 9.86 32 151150 3539 79589667
Quadriplegia 24.43 9.86 31 151151 3329 79589877
Pulse abnormal 24.25 9.86 31 151151 3353 79589853
Peritoneal effluent abnormal 24.25 9.86 7 151175 36 79593170
Joint stiffness 24.16 9.86 25 151157 40805 79552401
Aggression 24.11 9.86 37 151145 50921 79542285
Fungal sepsis 23.98 9.86 23 151159 1807 79591399
Hypercholesterolaemia 23.96 9.86 7 151175 23088 79570118
Infusion site thrombosis 23.82 9.86 11 151171 245 79592961
Aspartate aminotransferase increased 23.71 9.86 382 150800 138259 79454947
COVID-19 pneumonia 23.70 9.86 113 151069 28736 79564470
Respiratory distress 23.43 9.86 190 150992 58149 79535057
Tachycardia 23.40 9.86 470 150712 177298 79415908
Peripheral coldness 23.32 9.86 75 151107 15895 79577311
Pancreatic enzyme abnormality 23.23 9.86 9 151173 127 79593079
Dehydration 23.05 9.86 625 150557 247562 79345644
Seasonal allergy 23.01 9.86 76 151106 16330 79576876
Blood sodium decreased 22.93 9.86 124 151058 33131 79560075
Lower respiratory tract infection bacterial 22.87 9.86 17 151165 939 79592267
Haemoptysis 22.83 9.86 183 150999 55816 79537390
Prescribed underdose 22.56 9.86 14 151168 29500 79563706
Obesity 22.54 9.86 20 151162 35105 79558101
Hypoalbuminaemia 22.53 9.86 90 151092 21207 79571999
Joint range of motion decreased 22.53 9.86 18 151164 33264 79559942
Vasodilatation 22.50 9.86 29 151153 3162 79590044
Vaginal flatulence 22.37 9.86 26 151156 2549 79590657
Cystic fibrosis lung 22.20 9.86 9 151173 144 79593062
Foot deformity 22.03 9.86 9 151173 24065 79569141
Cystic fibrosis related diabetes 21.93 9.86 10 151172 216 79592990
Vein disorder 21.89 9.86 37 151145 5145 79588061
Catheter site infection 21.72 9.86 43 151139 6752 79586454
Sleep disorder due to a general medical condition 21.71 9.86 68 151114 14209 79578997
Excessive eye blinking 21.57 9.86 21 151161 1680 79591526
Infusion site rash 21.56 9.86 21 151161 1681 79591525
Dry mouth 21.32 9.86 90 151092 87929 79505277
Urinary tract infection 21.31 9.86 676 150506 273836 79319370
Seroma 21.29 9.86 24 151158 2276 79590930
Nephrectomy 21.19 9.86 23 151159 2092 79591114
Fluid imbalance 21.15 9.86 13 151169 523 79592683
Poisoning deliberate 20.87 9.86 5 151177 18823 79574383
Drug dependence 20.87 9.86 28 151154 40741 79552465
Ear infection 20.85 9.86 124 151058 34308 79558898
Regurgitation 20.72 9.86 26 151156 2761 79590445
Mental status changes postoperative 20.56 9.86 9 151173 176 79593030
Urine analysis abnormal 20.52 9.86 41 151141 6479 79586727
Coordination abnormal 20.40 9.86 4 151178 17308 79575898
Amnesia 20.34 9.86 57 151125 63000 79530206
Disturbance in attention 20.31 9.86 41 151141 50760 79542446
Pregnancy 20.17 9.86 13 151169 26838 79566368
Sinusitis 20.09 9.86 499 150683 195002 79398204
Disability 20.09 9.86 4 151178 17116 79576090
Lung transplant 19.85 9.86 33 151149 4528 79588678
Blood creatinine decreased 19.77 9.86 45 151137 7780 79585426
Staphylococcus test positive 19.50 9.86 40 151142 6441 79586765
Pseudomonas infection 19.50 9.86 85 151097 20818 79572388
Septic shock 19.39 9.86 334 150848 122467 79470739
Ventricular fibrillation 19.35 9.86 115 151067 31811 79561395
Panic reaction 19.30 9.86 33 151149 4632 79588574
Hepatic cytolysis 19.25 9.86 14 151168 27137 79566069
Chemical peritonitis 19.21 9.86 10 151172 291 79592915
Intentional product use issue 19.13 9.86 190 150992 151922 79441284
Pruritus 19.10 9.86 923 150259 393725 79199481
Prostate cancer 18.98 9.86 21 151161 33247 79559959
Stress 18.92 9.86 82 151100 79530 79513676
Distal intestinal obstruction syndrome 18.84 9.86 14 151168 773 79592433
Fall 18.78 9.86 745 150437 486884 79106322
Corneal oedema 18.77 9.86 24 151158 2596 79590610
Sleep disorder 18.72 9.86 91 151091 85586 79507620
Blood phosphorus decreased 18.72 9.86 40 151142 6628 79586578
Fracture 18.62 9.86 9 151173 21792 79571414
Infusion site phlebitis 18.58 9.86 8 151174 150 79593056
Complication associated with device 18.56 9.86 74 151108 17422 79575784
Osteonecrosis 18.44 9.86 19 151163 31076 79562130
Discoloured vomit 18.28 9.86 18 151164 1460 79591746
Alanine aminotransferase increased 18.23 9.86 420 150762 162150 79431056
Disease recurrence 18.15 9.86 35 151147 44074 79549132
Cardiovascular disorder 18.13 9.86 75 151107 17950 79575256
Pulse absent 18.10 9.86 51 151131 10052 79583154
Procedural complication 18.10 9.86 44 151138 7939 79585267
Respiratory tract infection bacterial 18.09 9.86 21 151161 2056 79591150
Hypochloraemia 17.96 9.86 23 151159 2492 79590714
Anterior chamber inflammation 17.89 9.86 12 151170 562 79592644
Oropharyngeal discomfort 17.88 9.86 41 151141 7125 79586081
Heart rate increased 17.87 9.86 325 150857 120399 79472807
Blood pressure diastolic abnormal 17.87 9.86 7 151175 19195 79574011
Mental disorder 17.86 9.86 111 151071 31191 79562015
Joint effusion 17.72 9.86 6 151176 18008 79575198
Brain injury 17.65 9.86 55 151127 11462 79581744
Haemarthrosis 17.64 9.86 36 151146 5776 79587430
Cholestasis 17.64 9.86 46 151136 52063 79541143
Pneumonia aspiration 17.42 9.86 199 150983 66768 79526438
Abdominal pain upper 17.37 9.86 309 150873 223510 79369696
Erythema 17.36 9.86 550 150632 222740 79370466
Serratia infection 17.25 9.86 19 151163 1757 79591449
Post procedural complication 17.22 9.86 90 151092 23739 79569467
Cauda equina syndrome 17.20 9.86 17 151165 1386 79591820
Infusion site mass 17.15 9.86 18 151164 1575 79591631
Eyelid oedema 17.09 9.86 61 151121 13626 79579580
Impaired work ability 17.00 9.86 8 151174 19673 79573533
Therapeutic product effect incomplete 16.96 9.86 179 151003 141466 79451740
Steatorrhoea 16.89 9.86 14 151168 907 79592299
Hypoaldosteronism 16.88 9.86 10 151172 376 79592830
Basal cell carcinoma 16.87 9.86 28 151154 37347 79555859
Hepatic cirrhosis 16.85 9.86 25 151157 34881 79558325
Weight decreased 16.79 9.86 529 150653 354669 79238537
Musculoskeletal disorder 16.64 9.86 10 151172 21438 79571768
Bronchial disorder 16.59 9.86 22 151160 2467 79590739
Acute pulmonary oedema 16.57 9.86 62 151120 14168 79579038
Infusion site bruising 16.54 9.86 24 151158 2928 79590278
Product container issue 16.49 9.86 16 151166 1275 79591931
Angioedema 16.47 9.86 81 151101 75954 79517252
Tachyarrhythmia 16.46 9.86 39 151143 6923 79586283
Hyperchloraemia 16.44 9.86 15 151167 1106 79592100
Body temperature increased 16.42 9.86 142 151040 44278 79548928
Sinus tachycardia 16.37 9.86 123 151059 36785 79556421
Blood creatine increased 16.23 9.86 47 151135 9408 79583798
Nephrocalcinosis 16.22 9.86 17 151165 1485 79591721
Hepatitis 16.10 9.86 53 151129 55674 79537532
Multiple allergies 16.07 9.86 50 151132 10410 79582796
Erectile dysfunction 16.05 9.86 4 151178 14660 79578546
Confusion postoperative 15.98 9.86 8 151174 214 79592992
Therapeutic response unexpected 15.90 9.86 9 151173 19937 79573269
Gangrene 15.82 9.86 45 151137 8919 79584287
Pneumorrhachis 15.81 9.86 3 151179 0 79593206
Product barcode issue 15.81 9.86 3 151179 0 79593206
Exposure via contaminated device 15.81 9.86 3 151179 0 79593206
Sedation complication 15.80 9.86 5 151177 15664 79577542
Blood albumin decreased 15.78 9.86 89 151093 24154 79569052
Lip erosion 15.69 9.86 17 151165 1543 79591663
Diabetes mellitus 15.59 9.86 86 151096 78304 79514902
Abortion spontaneous 15.37 9.86 20 151162 29487 79563719
Dyspnoea paroxysmal nocturnal 15.32 9.86 20 151162 2208 79590998
Catheter site extravasation 15.29 9.86 10 151172 449 79592757
Sedation 15.24 9.86 49 151133 51846 79541360
Liver disorder 15.20 9.86 78 151104 72339 79520867
Anterior chamber disorder 15.19 9.86 7 151175 155 79593051
Coma 15.17 9.86 120 151062 100529 79492677
Systemic inflammatory response syndrome 15.10 9.86 52 151130 11413 79581793
Pancreatic failure 15.09 9.86 17 151165 1611 79591595
Serotonin syndrome 15.05 9.86 40 151142 44987 79548219
Blood test abnormal 15.01 9.86 70 151112 17640 79575566
Maternal exposure during pregnancy 14.98 9.86 176 151006 136362 79456844
Lymphadenectomy 14.96 9.86 15 151167 1244 79591962
Product substitution issue 14.95 9.86 10 151172 20246 79572960
Ulcer 14.92 9.86 21 151161 29951 79563255
Blood pressure systolic abnormal 14.91 9.86 7 151175 17240 79575966
Corneal disorder 14.89 9.86 20 151162 2271 79590935
Adverse drug reaction 14.81 9.86 70 151112 66322 79526884
Ischaemic cerebral infarction 14.78 9.86 21 151161 2514 79590692
Catheter site pain 14.73 9.86 32 151150 5364 79587842
Hepatotoxicity 14.72 9.86 49 151133 51303 79541903
Wrong product administered 14.71 9.86 44 151138 8968 79584238
Respiration abnormal 14.63 9.86 40 151142 7748 79585458
Psychotic disorder 14.44 9.86 36 151146 41366 79551840
Angina pectoris 14.40 9.86 50 151132 51682 79541524
Injury 14.35 9.86 87 151095 77409 79515797
Multiple sclerosis relapse 14.33 9.86 43 151139 46490 79546716
Tracheitis 14.29 9.86 15 151167 1313 79591893
Rash erythematous 14.28 9.86 170 151012 57599 79535607
Burning sensation 14.26 9.86 172 151010 58460 79534746
Neuroleptic malignant syndrome 14.03 9.86 19 151163 27540 79565666
Aortic valve stenosis 14.00 9.86 31 151151 5263 79587943
Device difficult to use 13.99 9.86 4 151178 13381 79579825
Normal newborn 13.97 9.86 37 151145 7035 79586171
Urinary tract pain 13.82 9.86 8 151174 288 79592918
Gastrointestinal stoma output increased 13.80 9.86 9 151173 402 79592804
Drug chemical incompatibility 13.77 9.86 6 151176 116 79593090
Transmission of an infectious agent via product 13.76 9.86 7 151175 194 79593012
Infusion site discomfort 13.75 9.86 15 151167 1372 79591834
Infusion site ischaemia 13.74 9.86 3 151179 3 79593203
Heparin-induced thrombocytopenia 13.71 9.86 45 151137 9637 79583569
Cardiac failure congestive 13.60 9.86 189 150993 142213 79450993
Respiratory syncytial virus infection 13.59 9.86 44 151138 9358 79583848
Laryngeal oedema 13.57 9.86 40 151142 8089 79585117
Gastrostomy tube site complication 13.56 9.86 7 151175 200 79593006
Status asthmaticus 13.56 9.86 13 151169 1021 79592185
Dysbiosis 13.53 9.86 14 151168 1205 79592001
Acute generalised exanthematous pustulosis 13.45 9.86 8 151174 17246 79575960
Unmasking of previously unidentified disease 13.43 9.86 18 151164 2039 79591167
Full blood count decreased 13.41 9.86 92 151090 26727 79566479
Upper airway obstruction 13.39 9.86 15 151167 1413 79591793
Drug tolerance decreased 13.34 9.86 4 151178 12974 79580232
Retching 13.34 9.86 67 151115 17400 79575806
Metabolic disorder 13.33 9.86 43 151139 9127 79584079
Transient ischaemic attack 13.31 9.86 53 151129 52642 79540564
Hypercalcaemia 13.25 9.86 121 151061 38309 79554897
Creatinine renal clearance decreased 13.21 9.86 10 151172 18992 79574214
Acidosis 13.16 9.86 73 151109 19689 79573517
Eructation 13.10 9.86 48 151134 10861 79582345
Vasculitis 13.09 9.86 17 151165 25085 79568121
Convulsions local 13.07 9.86 5 151177 68 79593138
Disseminated Bacillus Calmette-Guerin infection 13.07 9.86 7 151175 216 79592990
Proctitis 13.06 9.86 34 151148 6398 79586808
Incision site pain 13.02 9.86 21 151161 2809 79590397
Neuropathy peripheral 12.98 9.86 189 150993 141116 79452090
Hepatitis cholestatic 12.97 9.86 5 151177 13847 79579359
Disseminated intravascular coagulation 12.94 9.86 114 151068 35728 79557478
Sputum retention 12.91 9.86 13 151169 1084 79592122
Gastroenteritis viral 12.90 9.86 86 151096 24745 79568461
Exostosis 12.88 9.86 8 151174 16850 79576356
Feeling cold 12.88 9.86 96 151086 28633 79564573
Toxic skin eruption 12.80 9.86 14 151168 22279 79570927
Breast cancer female 12.79 9.86 3 151179 11458 79581748
Pharyngitis streptococcal 12.74 9.86 47 151135 10667 79582539
COVID-19 treatment 12.71 9.86 9 151173 461 79592745
Vitamin E decreased 12.69 9.86 4 151178 29 79593177
Device related sepsis 12.69 9.86 33 151149 6207 79586999
Contusion 12.64 9.86 202 150980 148574 79444632
Alanine aminotransferase decreased 12.64 9.86 15 151167 1504 79591702
Brain death 12.56 9.86 31 151151 5646 79587560
Hepatic cyst ruptured 12.53 9.86 3 151179 6 79593200
Wrong product stored 12.53 9.86 3 151179 6 79593200
Lower respiratory tract infection 12.52 9.86 171 151011 129049 79464157
Wound dehiscence 12.52 9.86 34 151148 6561 79586645
Moaning 12.52 9.86 13 151169 1124 79592082
Blood fibrinogen decreased 12.44 9.86 17 151165 1962 79591244
Cold sweat 12.41 9.86 69 151113 18630 79574576
Mental status changes 12.39 9.86 187 150995 66772 79526434
Injection site pruritus 12.36 9.86 40 151142 42243 79550963
Bronchopulmonary dysplasia 12.30 9.86 7 151175 244 79592962
Carpal tunnel syndrome 12.26 9.86 71 151111 19457 79573749
Lactobacillus test positive 12.24 9.86 4 151178 33 79593173
Brain oedema 12.24 9.86 86 151096 25177 79568029
Cardiovascular insufficiency 12.22 9.86 21 151161 2960 79590246
Myocardial infarction 12.21 9.86 261 150921 183868 79409338
Second primary malignancy 12.14 9.86 6 151176 14344 79578862
Skin ulcer 12.13 9.86 57 151125 54093 79539113
Bone disorder 12.12 9.86 11 151171 19102 79574104
Ankylosing spondylitis 12.12 9.86 4 151178 12201 79581005
Hypoaesthesia oral 12.10 9.86 56 151126 14068 79579138
Pemphigoid 12.08 9.86 7 151175 15308 79577898
Oliguria 12.06 9.86 62 151120 16247 79576959
Incontinence 12.02 9.86 56 151126 14108 79579098
Bronchial obstruction 12.01 9.86 20 151162 2748 79590458
Lactic acidosis 11.99 9.86 81 151101 70278 79522928
Cardiac disorder 11.92 9.86 183 150999 65574 79527632
Infusion site pruritus 11.90 9.86 25 151157 4093 79589113
Neutropenic sepsis 11.89 9.86 90 151092 26974 79566232
Death 11.87 9.86 1237 149945 565277 79027929
Blood urea increased 11.81 9.86 143 151039 48647 79544559
Leukostasis syndrome 11.80 9.86 5 151177 90 79593116
Skin fissures 11.78 9.86 5 151177 13068 79580138
Progressive multifocal leukoencephalopathy 11.76 9.86 13 151169 20587 79572619
Coagulopathy 11.73 9.86 112 151070 35894 79557312
Hypophysitis 11.71 9.86 25 151157 4141 79589065
Cystic fibrosis hepatic disease 11.65 9.86 4 151178 39 79593167
Intestinal ischaemia 11.65 9.86 53 151129 13217 79579989
Multimorbidity 11.63 9.86 14 151168 1425 79591781
Postoperative wound infection 11.56 9.86 52 151130 12909 79580297
Peripheral venous disease 11.55 9.86 8 151174 15901 79577305
Eye infection 11.52 9.86 49 151133 11871 79581335
Poor feeding infant 11.51 9.86 6 151176 175 79593031
Bladder cancer 11.50 9.86 12 151170 19514 79573692
Leukoplakia oral 11.47 9.86 7 151175 278 79592928
Congestive cardiomyopathy 11.46 9.86 4 151178 11776 79581430
Extradural haematoma 11.45 9.86 20 151162 2856 79590350
Body temperature abnormal 11.45 9.86 18 151164 2357 79590849
Transurethral resection syndrome 11.43 9.86 3 151179 10 79593196
Photosensitivity reaction 11.34 9.86 14 151168 21113 79572093
Oxygen saturation immeasurable 11.31 9.86 4 151178 43 79593163
Blood chloride increased 11.24 9.86 28 151154 5128 79588078
Pseudohyperphosphataemia 11.21 9.86 3 151179 11 79593195
Injection site bruising 11.16 9.86 40 151142 40962 79552244
Limb discomfort 11.12 9.86 29 151153 32821 79560385
Thrombocytopenia 11.10 9.86 612 150570 264647 79328559
Vascular compression 11.10 9.86 9 151173 565 79592641
Peritoneal disorder 11.10 9.86 10 151172 725 79592481
Vertigo 11.06 9.86 81 151101 69001 79524205
Therapy partial responder 11.05 9.86 10 151172 17387 79575819
Schizophrenia 10.90 9.86 8 151174 15432 79577774
Hypersensitivity 10.88 9.86 397 150785 261842 79331364
Neutrophil count increased 10.88 9.86 94 151088 29302 79563904
Carbon dioxide increased 10.83 9.86 17 151165 2223 79590983
Vulva cyst 10.81 9.86 3 151179 13 79593193
Visual impairment 10.80 9.86 117 151065 92014 79501192
Chest pain 10.79 9.86 646 150536 281658 79311548
Infusion site urticaria 10.78 9.86 12 151170 1122 79592084
Dry skin 10.75 9.86 80 151102 67915 79525291
Feeling hot 10.74 9.86 166 151016 59568 79533638
Bone density decreased 10.67 9.86 6 151176 13341 79579865
Hyperglycaemia 10.63 9.86 190 150992 70145 79523061
Amylase abnormal 10.62 9.86 4 151178 52 79593154
Mental fatigue 10.59 9.86 9 151173 604 79592602
Tuberculosis 10.56 9.86 8 151174 15190 79578016
Female genital tract fistula 10.55 9.86 30 151152 5945 79587261
Injection site erythema 10.54 9.86 96 151086 78101 79515105
Apallic syndrome 10.53 9.86 11 151171 957 79592249
Synovial cyst 10.53 9.86 3 151179 10062 79583144
Encephalopathy 10.52 9.86 183 150999 67214 79525992
Pneumonitis 10.51 9.86 168 151014 60692 79532514
Drug-induced liver injury 10.49 9.86 180 151002 65937 79527269
Delusion 10.48 9.86 14 151168 20409 79572797
Autonomic failure syndrome 10.46 9.86 3 151179 15 79593191
Metabolic acidosis 10.45 9.86 217 150965 82312 79510894
Lung consolidation 10.43 9.86 39 151143 8908 79584298
Orthostatic hypotension 10.42 9.86 63 151119 56101 79537105
Haemolysis 10.39 9.86 50 151132 12762 79580444
Abscess rupture 10.38 9.86 7 151175 331 79592875
Peritoneal fluid analysis abnormal 10.35 9.86 4 151178 56 79593150
Cataract 10.35 9.86 72 151110 62048 79531158
Urine output decreased 10.34 9.86 64 151118 17958 79575248
Atelectasis 10.34 9.86 100 151082 32157 79561049
Vascular parkinsonism 10.33 9.86 5 151177 124 79593082
Hyperaemia 10.33 9.86 20 151162 3090 79590116
Uveitis 10.31 9.86 10 151172 16820 79576386
Prescribed overdose 10.28 9.86 37 151145 37846 79555360
Extrapyramidal disorder 10.22 9.86 17 151165 22662 79570544
Nervousness 10.20 9.86 31 151151 33384 79559822
Hepatic cyst 10.20 9.86 30 151152 6059 79587147
Stoma complication 10.18 9.86 10 151172 809 79592397
Tongue disorder 10.18 9.86 7 151175 13968 79579238
Intervertebral disc degeneration 10.11 9.86 9 151173 15776 79577430
Neoplasm progression 10.11 9.86 57 151125 51625 79541581
Dyskinesia 10.10 9.86 47 151135 44726 79548480
Glycosylated haemoglobin increased 10.09 9.86 13 151169 19247 79573959
Hot flush 9.95 9.86 62 151120 54815 79538391
Lower limb fracture 9.92 9.86 18 151164 23197 79570009

FDA Adverse Event Reporting System (Pediatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Neurotoxicity 32.17 25.92 8 294 8 89482
Bone marrow failure 32.17 25.92 8 294 8 89482
Gasping syndrome 32.17 25.92 8 294 8 89482
Toxicity to various agents 31.62 25.92 15 287 199 89291
Circulatory collapse 30.07 25.92 10 292 46 89444

Pharmacologic Action:

SourceCodeDescription
ATC A12CA01 ALIMENTARY TRACT AND METABOLISM
MINERAL SUPPLEMENTS
OTHER MINERAL SUPPLEMENTS
Sodium
ATC B05CB01 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
IRRIGATING SOLUTIONS
Salt solutions
ATC B05XA03 BLOOD AND BLOOD FORMING ORGANS
BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
I.V. SOLUTION ADDITIVES
Electrolyte solutions
ATC S01XA03 SENSORY ORGANS
OPHTHALMOLOGICALS
OTHER OPHTHALMOLOGICALS
Other ophthalmologicals
CHEBI has role CHEBI:79314 flame retardants
CHEBI has role CHEBI:149552 emetics

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

SpeciesUseRelation
Multiple Species Restore circulatory volume and maintain blood pressure in animals being treated for shock Indication
Multiple Species Early treatment of scouring Indication
Multiple Species Treatment following intravenous fluid therapy Indication
Multiple Species Early treatment of scouring Indication

🐶 Veterinary products

ProductApplicantIngredients
Intragel Zoetis Inc. 2
Re-Sorb, Vytrate Zoetis Inc. 6

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
0.21GM/100ML;2.8GM/100ML;9.07GM/100ML NORMOCARB HF 25 DIALYSIS SUPS N021910 July 26, 2006 RX SOLUTION INJECTION 7300674 March 4, 2023 USE AS REPLACEMENT SOLUTION, HEMOFILTRATION SOLUTION OR HEMODIAFILTRATION SOLUTION IN CONTINUOUS RENAL REPLACEMENT THERAPY
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 10792306 March 9, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 11529368 March 9, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 9592252 Aug. 11, 2032 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 10918723 Sept. 10, 2033 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS
7.54GM;140GM;2.2GM;48.11GM;5.2GM;9GM PLENVU SALIX N209381 May 4, 2018 RX FOR SOLUTION ORAL 9326969 Sept. 10, 2033 FOR CLEANSING OF THE COLON IN PREPARATION FOR COLONOSCOPY IN ADULTS

Orange Book exclusivity data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRouteExclusivity dateDescription
234MG/ML SODIUM CHLORIDE 23.4% FRESENIUS KABI USA A217796 July 11, 2023 RX INJECTABLE INJECTION Jan. 23, 2024 COMPETITIVE GENERIC THERAPY
0.9GM/BOT;178.7GM/BOT;1.12GM/BOT;0.5GM/BOT;7.3GM/BOT SUFLAVE BRAINTREE LABS N215344 June 15, 2023 RX FOR SOLUTION ORAL June 15, 2026 NEW PRODUCT

Bioactivity Summary:

None

External reference:

IDSource
4017444 VUID
N0000145832 NUI
D02056 KEGG_DRUG
4017444 VANDF
C0037494 UMLSCUI
CHEBI:26710 CHEBI
CHEMBL1200574 ChEMBL_ID
D012965 MESH_DESCRIPTOR_UI
DB09153 DRUGBANK_ID
4155 INN_ID
451W47IQ8X UNII
5234 PUBCHEM_CID
9863 RXNORM
5476 MMSL
6383 MMSL
d00438 MMSL
000759 NDDF
002238 NDDF
387390002 SNOMEDCT_US
70379000 SNOMEDCT_US
786818003 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
SODIUM CHLORIDE HUMAN PRESCRIPTION DRUG LABEL 1 0019-1188 INJECTION 0.90 mg INTRAVASCULAR NDA 17 sections
SODIUM CHLORIDE HUMAN PRESCRIPTION DRUG LABEL 1 0019-1188 INJECTION 0.90 mg INTRAVASCULAR NDA 17 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-0795 SOLUTION 6.40 mg OPHTHALMIC NDA 9 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-0795 SOLUTION 6.40 mg OPHTHALMIC NDA 9 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-0795 SOLUTION 6.40 mg OPHTHALMIC NDA 9 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-0795 SOLUTION 6.40 mg OPHTHALMIC NDA 9 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-1795 SOLUTION 6.40 mg OPHTHALMIC NDA 9 sections
BSS HUMAN PRESCRIPTION DRUG LABEL 6 0065-1795 SOLUTION 6.40 mg OPHTHALMIC NDA 9 sections
Sodium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0264-1800 INJECTION, SOLUTION 9 mg INTRAVENOUS NDA 23 sections
Sodium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0264-1800 INJECTION, SOLUTION 9 mg INTRAVENOUS NDA 23 sections
ProcalAmine HUMAN PRESCRIPTION DRUG LABEL 22 0264-1915 INJECTION 0.12 g INTRAVENOUS NDA 24 sections
ProcalAmine HUMAN PRESCRIPTION DRUG LABEL 22 0264-1915 INJECTION 0.12 g INTRAVENOUS NDA 24 sections
HyperlyteCR HUMAN PRESCRIPTION DRUG LABEL 5 0264-1943 INJECTION, SOLUTION, CONCENTRATE 1.17 g INTRAVENOUS UNAPPROVED DRUG OTHER 18 sections
HyperlyteCR HUMAN PRESCRIPTION DRUG LABEL 5 0264-1943 INJECTION, SOLUTION, CONCENTRATE 1.17 g INTRAVENOUS UNAPPROVED DRUG OTHER 18 sections
Balanced Salt HUMAN PRESCRIPTION DRUG LABEL 6 0264-1945 SOLUTION 6.40 mg IRRIGATION ANDA 11 sections
HESPAN HUMAN PRESCRIPTION DRUG LABEL 2 0264-1965 INJECTION, SOLUTION 0.90 g INTRAVENOUS NDA 22 sections
HESPAN HUMAN PRESCRIPTION DRUG LABEL 2 0264-1965 INJECTION, SOLUTION 0.90 g INTRAVENOUS NDA 22 sections
Sodium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0264-2201 IRRIGANT 0.90 g IRRIGATION NDA 23 sections
Sodium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0264-2201 IRRIGANT 0.90 g IRRIGATION NDA 23 sections
Sodium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0264-2201 IRRIGANT 0.90 g IRRIGATION NDA 23 sections
Sodium Chloride HUMAN PRESCRIPTION DRUG LABEL 1 0264-2201 IRRIGANT 0.90 g IRRIGATION NDA 23 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.86 g IRRIGATION NDA 22 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.86 g IRRIGATION NDA 22 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.86 g IRRIGATION NDA 22 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.86 g IRRIGATION NDA 22 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.86 g IRRIGATION NDA 22 sections
Ringers HUMAN PRESCRIPTION DRUG LABEL 3 0264-2202 IRRIGANT 0.86 g IRRIGATION NDA 22 sections
Lactated Ringers HUMAN PRESCRIPTION DRUG LABEL 4 0264-2203 IRRIGANT 0.60 g IRRIGATION NDA 18 sections
Lactated Ringers HUMAN PRESCRIPTION DRUG LABEL 4 0264-2203 IRRIGANT 0.60 g IRRIGATION NDA 18 sections
Lactated Ringers HUMAN PRESCRIPTION DRUG LABEL 4 0264-2203 IRRIGANT 0.60 g IRRIGATION NDA 18 sections