asparagine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
4126 70-47-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • asparagine
  • L-asparagine
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
  • Molecular weight: 132.12
  • Formula: C4H8N2O3
  • CLOGP: -3.54
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 106.41
  • ALOGS: 0.10
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:27027 trace elements
CHEBI has role CHEBI:50733 nutritional supplement
CHEBI has role CHEBI:75771 mus musculus metabolite
CHEBI has role CHEBI:75772 baker's yeast metabolite
CHEBI has role CHEBI:76924 plant metabolites
CHEBI has role CHEBI:76971 e.coli metabolites
CHEBI has role CHEBI:77746 h. sapiens metabolites
CHEBI has role CHEBI:83056 daphnia magna metabolites
CHEBI has role CHEBI:84735 algal metabolites

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.1 acidic
pKa2 12.1 acidic
pKa3 8.83 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
5Z33R5TKO7 UNII
N0000170238 NUI
D09738 KEGG_DRUG
C0003995 UMLSCUI
CHEBI:22653 CHEBI
ASN PDB_CHEM_ID
CHEMBL58832 ChEMBL_ID
DB00174 DRUGBANK_ID
D001216 MESH_DESCRIPTOR_UI
6267 PUBCHEM_CID
4533 IUPHAR_LIGAND_ID
1157 RXNORM
006909 NDDF
34744002 SNOMEDCT_US
87136001 SNOMEDCT_US

Pharmaceutical products:

None