prasterone sulfate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
androgens/anabolic steroids 4049 651-48-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • prasterone sulfate
  • dehydroandrosterone sulfate
  • dehydroepiandrosterone monosulfate
  • dehydroepiandrosterone sulfate
  • dehydroepiandrosterone sulphate
  • dehydroisoandrosterone sulfate
The circulating form of a major C19 steroid produced primarily by the ADRENAL CORTEX. DHEA sulfate serves as a precursor for TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE.
  • Molecular weight: 368.49
  • Formula: C19H28O5S
  • CLOGP: 3.01
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 80.67
  • ALOGS: -4.66
  • ROTB: 2
  • Status: ONP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
CHEBI has role CHEBI:75771 Mus musculus metabolites
CHEBI has role CHEBI:77194 ATP:pantothenate 4-phosphotransferase inhibitor
CHEBI has role CHEBI:77746 Homo sapiens metabolite
CHEBI has role CHEBI:50113 androgene

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.53 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4021360 VANDF
4036745 VANDF
C0057277 UMLSCUI
CHEBI:16814 CHEBI
CHEBI:28689 CHEBI
ZQK PDB_CHEM_ID
DB05804 DRUGBANK_ID
12594 PUBCHEM_CID
4528 IUPHAR_LIGAND_ID
57B09Q7FJR UNII
DB01708 DRUGBANK_ID
3143 RXNORM
131731 MMSL
20676 MMSL
32118 MMSL
73034 MMSL
d04425 MMSL
004609 NDDF
103044003 SNOMEDCT_US
413963008 SNOMEDCT_US
78316004 SNOMEDCT_US
D019314 MESH_DESCRIPTOR_UI
C0011185 UMLSCUI
2869 INN_ID
5881 PUBCHEM_CID

Pharmaceutical products:

None