artemisinin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antimalarial agents, artemisinin related compounds | 3871 | 63968-64-9 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
antimalarial from Chinese medicinal herb Artemisia annua
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 1 | g | O |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.05 mg/mL | Bocci G, Oprea TI, Benet LZ |
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Bocci G, Oprea TI, Benet LZ |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | P01BE01 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS ANTIMALARIALS Artemisinin and derivatives, plain |
| ATC | P01BF07 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS ANTIMALARIALS Artemisinin and derivatives, combinations |
| ATC | P01BF08 | ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS ANTIPROTOZOALS ANTIMALARIALS Artemisinin and derivatives, combinations |
| MeSH PA | D000890 | Anti-Infective Agents |
| CHEBI has role | CHEBI:38068 | antimalarials |
| CHEBI has role | CHEBI:76924 | plant metabolites |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Falciparum malaria | indication | 62676009 | DOID:14067 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Cytochrome P450 1A2 | Enzyme | IC50 | 5.70 | DRUG MATRIX |
External reference:
| ID | Source |
|---|---|
| D02481 | KEGG_DRUG |
| C0052430 | UMLSCUI |
| CHEBI:223316 | CHEBI |
| CHEMBL567597 | ChEMBL_ID |
| DB13132 | DRUGBANK_ID |
| C031327 | MESH_SUPPLEMENTAL_RECORD_UI |
| 68827 | PUBCHEM_CID |
| 9954 | IUPHAR_LIGAND_ID |
| 5954 | INN_ID |
| 9RMU91N5K2 | UNII |
| 2367409 | RXNORM |
| 019140 | NDDF |
| 895350006 | SNOMEDCT_US |
| 96106001 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| ArtemiC Rescue | HUMAN OTC DRUG LABEL | 4 | 83278-001 | SPRAY, SUSPENSION | 0.60 g | ORAL | unapproved drug other | 11 sections |