chlorthenoxazine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3707 132-89-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • chlorthenoxazine
  • apirazin
  • chlorethylbenzmethoxazone
  • ossapirina
  • ossazone
  • piroxina
  • reumagrip
  • valmorin
  • Molecular weight: 211.65
  • Formula: C10H10ClNO2
  • CLOGP: 1.55
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 1
  • TPSA: 38.33
  • ALOGS: -2.16
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.97 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Poly [ADP-ribose] polymerase 1 Enzyme IC50 5.07 CHEMBL

External reference:

IDSource
C0055478 UMLSCUI
CHEBI:134882 CHEBI
CHEMBL124815 ChEMBL_ID
8602 PUBCHEM_CID
962 INN_ID
KA0B657LV3 UNII
20891 RXNORM
004336 NDDF

Pharmaceutical products:

None