bietaserpine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
derivatives of Rauwolfia alkaloids 3687 53-18-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bietaserpine
  • diethylaminoreserpin
  • N-Diethylaminoethylreserpine
hypotensive agent; structure
  • Molecular weight: 707.87
  • Formula: C39H53N3O9
  • CLOGP: 5.64
  • LIPINSKI: 3
  • HAC: 12
  • HDO: 0
  • TPSA: 110.16
  • ALOGS: -5.02
  • ROTB: 15

Drug dosage:

DoseUnitRoute
15 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C02AA07 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Rauwolfia alkaloids
ATC C02AA57 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIADRENERGIC AGENTS, CENTRALLY ACTING
Rauwolfia alkaloids
ATC C02LA07 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIHYPERTENSIVES AND DIURETICS IN COMBINATION
Rauwolfia alkaloids and diuretics in combination
MeSH PA D000959 Antihypertensive Agents
MeSH PA D002317 Cardiovascular Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 9.96 Basic
pKa2 7.24 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07167 KEGG_DRUG
C0053565 UMLSCUI
CHEBI:125518 CHEBI
CHEMBL3989595 ChEMBL_ID
DB13575 DRUGBANK_ID
C004538 MESH_SUPPLEMENTAL_RECORD_UI
1686 INN_ID
0P5B94FVD5 UNII
20054848 PUBCHEM_CID

Pharmaceutical products:

None