Molfile
Inchi
Smiles
Synonyms:
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ICI 176334
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ICI-176334
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bicalutamide
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casodex
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Bicalutamide is a non-steroidal androgen receptor inhibitor. It competitively inhibits the action of androgens by binding to cytosol androgen receptors in the target tissue. Prostatic carcinoma is known to be androgen sensitive and responds to treatment that counteracts the effect of androgen and/or removes the source of androgen.
- Molecular weight: 430.37
- Formula: C18H14F4N2O4S
- CLOGP: 2.71
- LIPINSKI: 0
- HAC: 6
- HDO: 2
- TPSA: 107.26
- ALOGS: -4.67
- ROTB: 6
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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