tetrofosmin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
insecticides, anthelminthics, pesticides etc., phosphorous derivatives 3592 127502-06-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • tetrofosmin
Tetrofosmin is a diagnostic agent used to assess areas of reversible myocardial ischemia in the presence or absence of infracted myocardium and is also used to assess ventricular function.
  • Molecular weight: 382.46
  • Formula: C18H40O4P2
  • CLOGP: -0.69
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 36.92
  • ALOGS: -5.76
  • ROTB: 19

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
No adverse event 286.67 81.48 56 162 41349 63447455
Radioisotope scan abnormal 277.47 81.48 29 189 204 63488600

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Radioisotope scan abnormal 381.18 81.83 41 178 203 34956509
No adverse event 349.82 81.83 66 153 22861 34933851

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
No adverse event 359.25 59.55 69 265 37123 79706931
Radioisotope scan abnormal 305.20 59.55 35 299 495 79743559
Drug ineffective 60.66 59.55 43 291 1080870 78663184

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D06094 KEGG_DRUG
C1366036 UMLSCUI
CHEMBL1615784 ChEMBL_ID
DB11180 DRUGBANK_ID
4274 PUBCHEM_CID
6886 INN_ID
3J0KPB596Q UNII
1311569 RXNORM
23732 MMSL
d06761 MMSL
009786 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Myoview HUMAN PRESCRIPTION DRUG LABEL 1 17156-024 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 0.23 mg INTRAVENOUS NDA 26 sections
Myoview HUMAN PRESCRIPTION DRUG LABEL 1 17156-024 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 0.23 mg INTRAVENOUS NDA 26 sections
Myoview HUMAN PRESCRIPTION DRUG LABEL 1 17156-026 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 1.38 mg INTRAVENOUS NDA 24 sections
Myoview HUMAN PRESCRIPTION DRUG LABEL 1 17156-026 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 1.38 mg INTRAVENOUS NDA 24 sections
Myoview HUMAN PRESCRIPTION DRUG LABEL 1 17156-026 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 1.38 mg INTRAVENOUS NDA 24 sections
Tetrofosmin HUMAN PRESCRIPTION DRUG LABEL 1 51808-223 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 0.35 mg INTRAVENOUS Unapproved drug other 7 sections
Tetrofosmin HUMAN PRESCRIPTION DRUG LABEL 1 51808-223 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 0.35 mg INTRAVENOUS Unapproved drug other 7 sections