talastine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antihistaminics 3579 16188-61-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • talastine monohydrochloride
  • talastine hydrochloride
  • talastine HCl
  • ahanon
  • talastine
  • benzylphthalazone
  • Molecular weight: 307.40
  • Formula: C19H21N3O
  • CLOGP: 2.15
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 0
  • TPSA: 35.91
  • ALOGS: -3.65
  • ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R06AB07 RESPIRATORY SYSTEM
ANTIHISTAMINES FOR SYSTEMIC USE
ANTIHISTAMINES FOR SYSTEMIC USE
Substituted alkylamines

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.76 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Histamine H1 receptor GPCR ANTAGONIST SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE

External reference:

IDSource
D07399 KEGG_DRUG
16188-76-4 SECONDARY_CAS_RN
C0084711 UMLSCUI
CHEBI:135308 CHEBI
CHEMBL1742439 ChEMBL_ID
DB13349 DRUGBANK_ID
C009376 MESH_SUPPLEMENTAL_RECORD_UI
65624 PUBCHEM_CID
2402 INN_ID
49AB2PA48B UNII

Pharmaceutical products:

None