stallimycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
antibiotics, produced by Streptomyces strains	3553	636-47-5

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

stallimycin
Distamycin 3
Distamycin A
stallimycin hydrochloride
stallimycin HCl

Molecular weight: 481.52
Formula: C22H27N9O4
CLOGP: -0.25
LIPINSKI: 2
HAC: 13
HDO: 6
TPSA: 181.06
ALOGS: -3.37
ROTB: 9

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D000890	Anti-Infective Agents
MeSH PA	D000998	Antiviral Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	12.13	acidic
pKa2	12.94	acidic
pKa3	13.41	acidic
pKa4	10.01	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
DNA topoisomerase 1	Enzyme	P11387	TOP1_HUMAN		IC50	5.57		CHEMBL
GTPase HRas	Cytosolic other	P01112	RASH_HUMAN		IC50	6.70		CHEMBL
Estrogen receptor	Nuclear hormone receptor	P03372 Q92731	ESR1_HUMAN ESR2_HUMAN		IC50	7.70		CHEMBL

External reference:

ID	Source
D05916	KEGG_DRUG
C0244119	UMLSCUI
DMY	PDB_CHEM_ID
CHEMBL11252	ChEMBL_ID
C030000	MESH_SUPPLEMENTAL_RECORD_UI
3346	INN_ID
6576-51-8	SECONDARY_CAS_RN
80O63P88IS	UNII
3115	PUBCHEM_CID
CHEMBL19687	ChEMBL_ID

Pharmaceutical products:

None