revaprazan Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
3525 199463-33-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • revaprazan hydrochloride
  • revaprazan
  • revaprazan HCl
  • YH 1885
  • revanex
  • YH1885
proton pump inhibitor
  • Molecular weight: 362.45
  • Formula: C22H23FN4
  • CLOGP: 6.21
  • LIPINSKI: 1
  • HAC: 4
  • HDO: 1
  • TPSA: 41.05
  • ALOGS: -4.53
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Sept. 15, 2005 Korean Food and Drug Administration (KFDA)

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

None

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Duodenal ulcer disease indication 51868009 DOID:1724
Gastro-esophageal reflux disease with esophagitis indication 266433003
Gastric ulcer indication 397825006 DOID:10808

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 6.34 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Potassium-transporting ATPase Transporter INHIBITOR SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE

External reference:

IDSource
D05722 KEGG_DRUG
178307-42-1 SECONDARY_CAS_RN
C2699073 UMLSCUI
CHEBI:135529 CHEBI
CHEMBL1618279 ChEMBL_ID
CHEMBL1257753 ChEMBL_ID
DB16308 DRUGBANK_ID
C108798 MESH_SUPPLEMENTAL_RECORD_UI
8415 INN_ID
5P184180P5 UNII
204103 PUBCHEM_CID

Pharmaceutical products:

None