All FDA-approved EMA-approved PMDA-approved
Target Card Uniprot Example: P23975

resorcinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	3524	108-46-3

Description:

Molecule	Description
Molfile Inchi Smiles Synonyms: resorcinol resorcin benzene-1,3-diol	an antiseptic and disinfectant used for temporary relief of itching Molecular weight: 110.11 Formula: C6H6O2 CLOGP: 0.81 LIPINSKI: 0 HAC: 2 HDO: 2 TPSA: 40.46 ALOGS: -0.13 ROTB: 0

Drug dosage:

None

ADMET properties:

None

Approvals:

Date	Agency	Company	Orphan
None	FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
ATC	D10AX02	DERMATOLOGICALS ANTI-ACNE PREPARATIONS ANTI-ACNE PREPARATIONS FOR TOPICAL USE Other anti-acne preparations for topical use
ATC	S01AX06	SENSORY ORGANS OPHTHALMOLOGICALS ANTIINFECTIVES Other antiinfectives
CHEBI has role	CHEBI:91025	EPO inhibitor
CHEBI has role	CHEBI:139492	sensitizers

Drug Use | Suggest Off label Use Form| |View source of the data|

Disease	Relation	SNOMED_ID	DOID
Acne vulgaris	indication	88616000
Skin irritation	indication	367466007
Acneiform eruption	indication	402644006
Itching of skin	indication	418363000
Minor Skin Wound Pain	indication
Folliculitis	contraindication	13600006	DOID:4409
Infection of skin AND/OR subcutaneous tissue	contraindication	19824006
Methemoglobinemia	contraindication	38959009	DOID:10783
Conduction disorder of the heart	contraindication	44808001
Diabetes mellitus	contraindication	73211009	DOID:9351
Decreased respiratory function	contraindication	80954004
Kidney disease	contraindication	90708001	DOID:557
Anemia due to enzyme deficiency	contraindication	111577008
Deficiency of glucose-6-phosphate dehydrogenase	contraindication	124134002	DOID:2862
Deficiency of cytochrome-b>5< reductase	contraindication	124184009
Open wound	contraindication	125643001
Seizure disorder	contraindication	128613002
Condyloma acuminatum	contraindication	240542006	DOID:11168
Eruption of skin	contraindication	271807003	DOID:0050486
Peripheral vascular disease	contraindication	400047006
Blister	contraindication	417237009
Denuded skin	contraindication	418242004
Inflammatory dermatosis	contraindication	703938007

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	9.01	acidic
pKa2	11.02	acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Carbonic anhydrase 2	Enzyme	P00918	CAH2_HUMAN		Ki	5.11		CHEMBL
Carbonic anhydrase 9	Enzyme	Q16790	CAH9_HUMAN		Ki	4.16		CHEMBL
Carbonic anhydrase 12	Enzyme	O43570	CAH12_HUMAN		Ki	5.12		CHEMBL
Carbonic anhydrase 5A, mitochondrial	Enzyme	P35218	CAH5A_HUMAN		Ki	5.06		CHEMBL
Carbonic anhydrase 5B, mitochondrial	Enzyme	Q9Y2D0	CAH5B_HUMAN		Ki	5.15		CHEMBL
Carbonic anhydrase 14	Enzyme	Q9ULX7	CAH14_HUMAN		Ki	4.97		CHEMBL
Carbonic anhydrase 13	Enzyme		CAH13_MOUSE		Ki	4.20		CHEMBL
Prostaglandin G/H synthase 1	Enzyme		PGH1_SHEEP		Kd	4.06		CHEMBL
Carbonic anhydrase	Enzyme		Q2PCB5_DICLA		Ki	5.19		CHEMBL

External reference:

ID	Source
YUL4LO94HK	UNII
4019032	VUID
N0000147303	NUI
D00133	KEGG_DRUG
4019032	VANDF
C0073085	UMLSCUI
CHEBI:27810	CHEBI
RCO	PDB_CHEM_ID
CHEMBL24147	ChEMBL_ID
5054	PUBCHEM_CID
DB11085	DRUGBANK_ID
C031389	MESH_SUPPLEMENTAL_RECORD_UI
35382	RXNORM
5052	MMSL
5418	MMSL
001950	NDDF
411296008	SNOMEDCT_US
78032005	SNOMEDCT_US

Pharmaceutical products:

Product	Category	Ingredients	NDC	Form	Quantity	Route	Marketing	Label
good sense vagicaineanti itch	HUMAN OTC DRUG LABEL	2	0113-0142	CREAM	3 g	TOPICAL	OTC monograph not final	13 sections
Adult Acnomel Tinted	HUMAN OTC DRUG LABEL	2	0295-9116	CREAM	2 g	TOPICAL	OTC monograph final	12 sections
Anti-Itch Regular Strength	HUMAN OTC DRUG LABEL	2	0363-0621	CREAM	2 g	TOPICAL	OTC monograph final	11 sections
Well at Walgreens Anti-Itch Maximum Strength	HUMAN OTC DRUG LABEL	2	0363-0674	CREAM	3 g	TOPICAL	OTC monograph final	11 sections
Anti-Itch Medicated Maximum Strength	HUMAN OTC DRUG LABEL	2	0363-2311	CREAM	30 mg	TOPICAL	OTC MONOGRAPH NOT FINAL	11 sections
Tinted Acne Treatment	HUMAN OTC DRUG LABEL	2	0363-7783	CREAM	2 g	TOPICAL	OTC monograph final	7 sections
REZAMID	HUMAN OTC DRUG LABEL	2	11086-022	LOTION	2 g	TOPICAL	OTC monograph final	11 sections
REZAMID	HUMAN OTC DRUG LABEL	2	11086-022	LOTION	2 1	TOPICAL	OTC monograph final	11 sections
VAGISIL Anti-Itch Medicated Creme Maximum Strength	HUMAN OTC DRUG LABEL	2	11509-4402	CREAM	30 mg	TOPICAL	OTC MONOGRAPH NOT FINAL	11 sections
VAGISIL Anti-Itch Creme Regular Strength	HUMAN OTC DRUG LABEL	2	11509-5103	CREAM	20 mg	TOPICAL	OTC MONOGRAPH NOT FINAL	10 sections
Up and up vagicaine	HUMAN OTC DRUG LABEL	2	11673-142	CREAM	3 g	TOPICAL	OTC monograph not final	13 sections
BENZOCAINE and RESORCINOL	HUMAN OTC DRUG LABEL	2	11822-2890	OINTMENT	20 mg	TOPICAL	OTC monograph not final	7 sections
Rite Aid Original Strength Vagicaine	HUMAN OTC DRUG LABEL	2	11822-2891	CREAM	20 mg	TOPICAL	OTC monograph not final	7 sections
Vagicaine Medicated Maximum Strength	HUMAN OTC DRUG LABEL	2	11822-5880	CREAM	30 mg	TOPICAL	OTC MONOGRAPH NOT FINAL	11 sections
Rite Aid Original Strength Vagicaine	HUMAN OTC DRUG LABEL	2	11822-9974	CREAM	2 g	TOPICAL	OTC monograph not final	9 sections
signature care vagicaine	HUMAN OTC DRUG LABEL	2	21130-142	CREAM	3 g	TOPICAL	OTC monograph not final	13 sections
Budpak Feminine Anti-Itch	HUMAN OTC DRUG LABEL	2	27293-022	CREAM	0.02 g	TOPICAL	OTC monograph not final	10 sections
Vagicaine	HUMAN OTC DRUG LABEL	2	29500-7820	CREAM	0.85 g	TOPICAL	OTC monograph not final	12 sections
Vagicaine	HUMAN OTC DRUG LABEL	2	29500-7820	CREAM	0.85 g	TOPICAL	OTC monograph not final	12 sections
AssuredFeminine Anti-itch	HUMAN OTC DRUG LABEL	2	33992-2014	CREAM	2 g	TOPICAL	OTC monograph not final	10 sections
VagicaineMaximum Strength	HUMAN OTC DRUG LABEL	2	41250-142	CREAM	3 g	TOPICAL	OTC monograph not final	13 sections
good neighbor pharmacy vagicaine	HUMAN OTC DRUG LABEL	2	46122-576	CREAM	3 g	TOPICAL	OTC monograph not final	13 sections
Well at Walgreens Anti-ItchMaximum Strength	HUMAN OTC DRUG LABEL	2	47046-181	CREAM	3 g	TOPICAL	OTC monograph final	11 sections
Leader Anti-Itch Maximum Strength	HUMAN OTC DRUG LABEL	2	49781-092	CREAM	30 mg	TOPICAL	OTC monograph final	11 sections
Family Wellness	HUMAN OTC DRUG LABEL	2	55621-016	CREAM	3 g	TOPICAL	OTC monograph not final	9 sections
OptimV Anti-ItchMaximum Strength	HUMAN OTC DRUG LABEL	2	55758-300	CREAM	3 g	TOPICAL	OTC monograph not final	13 sections
CLARIFYING MASK	HUMAN OTC DRUG LABEL	2	55878-102	PASTE	2 g	TOPICAL	OTC monograph final	10 sections
CLARIFYING MASK	HUMAN OTC DRUG LABEL	2	55878-106	PASTE	2 g	TOPICAL	OTC monograph final	11 sections
DG HealthFeminine Anti-itch	HUMAN OTC DRUG LABEL	2	55910-158	CREAM	3 g	TOPICAL	OTC monograph not final	11 sections
BENZOCAINE and RESORCINOL	HUMAN OTC DRUG LABEL	2	55910-185	CREAM	20 mg	TOPICAL	OTC monograph not final	7 sections