Stem definition | Drug id | CAS RN |
---|---|---|
monoamine oxydase (MAO)-inhibitors type B | 3521 | 136236-51-6 |
Dose | Unit | Route |
---|---|---|
1 | mg | O |
Property | Value | Reference |
---|---|---|
BA (Bioavailability) | 36 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
May 16, 2006 | FDA | TEVA | |
March 23, 2018 | PMDA | Takeda Pharmaceutical Company Limited |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hallucination | 222.89 | 22.18 | 102 | 4726 | 46555 | 50553741 |
Dyskinesia | 195.64 | 22.18 | 80 | 4748 | 27781 | 50572515 |
Hallucination, visual | 189.78 | 22.18 | 68 | 4760 | 16514 | 50583782 |
Serotonin syndrome | 124.05 | 22.18 | 56 | 4772 | 24657 | 50575639 |
Fall | 113.80 | 22.18 | 149 | 4679 | 334783 | 50265513 |
On and off phenomenon | 90.29 | 22.18 | 22 | 4806 | 1390 | 50598906 |
Bradykinesia | 76.17 | 22.18 | 24 | 4804 | 3919 | 50596377 |
Delusion | 72.88 | 22.18 | 30 | 4798 | 10539 | 50589757 |
Pleurothotonus | 66.79 | 22.18 | 17 | 4811 | 1284 | 50599012 |
Drug interaction | 63.16 | 22.18 | 86 | 4742 | 199535 | 50400761 |
Freezing phenomenon | 60.76 | 22.18 | 15 | 4813 | 1000 | 50599296 |
Tremor | 56.66 | 22.18 | 62 | 4766 | 114841 | 50485455 |
Confusional state | 52.67 | 22.18 | 76 | 4752 | 185852 | 50414444 |
Gambling disorder | 48.72 | 22.18 | 13 | 4815 | 1181 | 50599115 |
Orthostatic hypotension | 48.71 | 22.18 | 32 | 4796 | 29449 | 50570847 |
Sudden onset of sleep | 48.23 | 22.18 | 11 | 4817 | 521 | 50599775 |
Muscle rigidity | 42.18 | 22.18 | 20 | 4808 | 9809 | 50590487 |
Impulse-control disorder | 40.60 | 22.18 | 10 | 4818 | 660 | 50599636 |
Compulsive shopping | 39.91 | 22.18 | 10 | 4818 | 708 | 50599588 |
Hypersexuality | 39.08 | 22.18 | 9 | 4819 | 445 | 50599851 |
Stoma site discharge | 38.68 | 22.18 | 11 | 4817 | 1264 | 50599032 |
Labelled drug-drug interaction medication error | 35.06 | 22.18 | 18 | 4810 | 10459 | 50589837 |
Coronary artery dissection | 34.87 | 22.18 | 9 | 4819 | 718 | 50599578 |
Stoma site erythema | 33.05 | 22.18 | 9 | 4819 | 882 | 50599414 |
Altered state of consciousness | 31.91 | 22.18 | 22 | 4806 | 21888 | 50578408 |
Psychotic symptom | 30.32 | 22.18 | 9 | 4819 | 1203 | 50599093 |
Choking | 29.60 | 22.18 | 15 | 4813 | 8483 | 50591813 |
Serum serotonin increased | 29.47 | 22.18 | 6 | 4822 | 165 | 50600131 |
Compulsive hoarding | 28.79 | 22.18 | 5 | 4823 | 56 | 50600240 |
Agitation | 28.36 | 22.18 | 30 | 4798 | 53354 | 50546942 |
Anxiety | 28.05 | 22.18 | 56 | 4772 | 177550 | 50422746 |
Stoma site extravasation | 27.05 | 22.18 | 6 | 4822 | 250 | 50600046 |
Stoma site hypergranulation | 26.33 | 22.18 | 6 | 4822 | 283 | 50600013 |
Dementia | 25.53 | 22.18 | 17 | 4811 | 15980 | 50584316 |
Resting tremor | 25.38 | 22.18 | 7 | 4821 | 719 | 50599577 |
Cerebral atrophy | 24.88 | 22.18 | 11 | 4817 | 4590 | 50595706 |
Fracture | 24.74 | 22.18 | 17 | 4811 | 16816 | 50583480 |
Gait disturbance | 24.52 | 22.18 | 48 | 4780 | 149957 | 50450339 |
Parkinsonian gait | 23.79 | 22.18 | 6 | 4822 | 436 | 50599860 |
Nocturia | 23.79 | 22.18 | 12 | 4816 | 6718 | 50593578 |
Sleep talking | 23.63 | 22.18 | 7 | 4821 | 929 | 50599367 |
Balance disorder | 23.12 | 22.18 | 31 | 4797 | 70559 | 50529737 |
Dystonia | 22.29 | 22.18 | 14 | 4814 | 11912 | 50588384 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hallucination | 453.83 | 24.75 | 224 | 7446 | 44488 | 29522369 |
Impulse-control disorder | 286.80 | 24.75 | 66 | 7604 | 1159 | 29565698 |
Dyskinesia | 247.00 | 24.75 | 115 | 7555 | 19946 | 29546911 |
Hypersexuality | 208.33 | 24.75 | 52 | 7618 | 1304 | 29565553 |
Hallucination, visual | 178.31 | 24.75 | 84 | 7586 | 14931 | 29551926 |
Fall | 155.29 | 24.75 | 209 | 7461 | 176969 | 29389888 |
On and off phenomenon | 153.63 | 24.75 | 44 | 7626 | 1884 | 29564973 |
Gambling disorder | 153.11 | 24.75 | 42 | 7628 | 1533 | 29565324 |
Freezing phenomenon | 124.25 | 24.75 | 34 | 7636 | 1229 | 29565628 |
Orthostatic hypotension | 122.27 | 24.75 | 75 | 7595 | 22554 | 29544303 |
Confusional state | 121.27 | 24.75 | 157 | 7513 | 127720 | 29439137 |
Dopamine dysregulation syndrome | 117.13 | 24.75 | 25 | 7645 | 304 | 29566553 |
Delusion | 92.43 | 24.75 | 49 | 7621 | 11167 | 29555690 |
Serotonin syndrome | 74.61 | 24.75 | 50 | 7620 | 17462 | 29549395 |
Abnormal behaviour | 73.03 | 24.75 | 55 | 7615 | 23072 | 29543785 |
Resting tremor | 67.19 | 24.75 | 18 | 7652 | 599 | 29566258 |
Somnolence | 63.11 | 24.75 | 98 | 7572 | 93857 | 29473000 |
Dystonia | 59.57 | 24.75 | 35 | 7635 | 9714 | 29557143 |
Bradykinesia | 59.21 | 24.75 | 25 | 7645 | 3422 | 29563435 |
Muscle rigidity | 55.44 | 24.75 | 33 | 7637 | 9378 | 29557479 |
Compulsive shopping | 55.00 | 24.75 | 14 | 7656 | 380 | 29566477 |
Tremor | 52.59 | 24.75 | 79 | 7591 | 73459 | 29493398 |
Cogwheel rigidity | 50.75 | 24.75 | 17 | 7653 | 1226 | 29565631 |
Sudden onset of sleep | 50.58 | 24.75 | 13 | 7657 | 367 | 29566490 |
Stereotypy | 47.86 | 24.75 | 14 | 7656 | 645 | 29566212 |
Stoma site discharge | 47.42 | 24.75 | 15 | 7655 | 902 | 29565955 |
Cognitive disorder | 45.25 | 24.75 | 42 | 7628 | 23457 | 29543400 |
Balance disorder | 44.85 | 24.75 | 51 | 7619 | 36119 | 29530738 |
Supine hypertension | 43.12 | 24.75 | 11 | 7659 | 301 | 29566556 |
Akinesia | 42.94 | 24.75 | 17 | 7653 | 1973 | 29564884 |
Marasmus | 42.59 | 24.75 | 12 | 7658 | 483 | 29566374 |
Jealous delusion | 42.19 | 24.75 | 10 | 7660 | 200 | 29566657 |
Psychomotor hyperactivity | 41.22 | 24.75 | 26 | 7644 | 8187 | 29558670 |
Embedded device | 40.86 | 24.75 | 10 | 7660 | 230 | 29566627 |
Stoma site erythema | 39.66 | 24.75 | 12 | 7658 | 622 | 29566235 |
Hyperkinesia | 39.25 | 24.75 | 15 | 7655 | 1584 | 29565273 |
Sleep disorder | 38.34 | 24.75 | 39 | 7631 | 24347 | 29542510 |
Oesophageal achalasia | 37.64 | 24.75 | 10 | 7660 | 322 | 29566535 |
Anticholinergic syndrome | 35.60 | 24.75 | 12 | 7658 | 882 | 29565975 |
Rapid eye movement sleep behaviour disorder | 35.55 | 24.75 | 8 | 7662 | 126 | 29566731 |
Mesenteric artery thrombosis | 35.34 | 24.75 | 10 | 7660 | 409 | 29566448 |
Dementia | 35.18 | 24.75 | 27 | 7643 | 11631 | 29555226 |
Obsessive-compulsive personality disorder | 34.50 | 24.75 | 8 | 7662 | 145 | 29566712 |
Gait disturbance | 34.03 | 24.75 | 65 | 7605 | 73284 | 29493573 |
Paraphilia | 33.60 | 24.75 | 7 | 7663 | 75 | 29566782 |
Device dislocation | 32.33 | 24.75 | 18 | 7652 | 4509 | 29562348 |
Agitation | 32.28 | 24.75 | 52 | 7618 | 51252 | 29515605 |
Hyperthermia | 31.02 | 24.75 | 23 | 7647 | 9407 | 29557450 |
Psychotic disorder | 30.99 | 24.75 | 32 | 7638 | 20322 | 29546535 |
Thunderclap headache | 30.96 | 24.75 | 6 | 7664 | 43 | 29566814 |
Autonomic nervous system imbalance | 30.35 | 24.75 | 14 | 7656 | 2362 | 29564495 |
Therapeutic product effect variable | 30.20 | 24.75 | 13 | 7657 | 1864 | 29564993 |
Nocturia | 28.87 | 24.75 | 21 | 7649 | 8341 | 29558516 |
Restlessness | 28.76 | 24.75 | 32 | 7638 | 22113 | 29544744 |
Blood lactic acid | 28.02 | 24.75 | 8 | 7662 | 338 | 29566519 |
Disturbance in attention | 27.89 | 24.75 | 31 | 7639 | 21393 | 29545464 |
Fracture | 27.50 | 24.75 | 18 | 7652 | 6035 | 29560822 |
Toxicity to various agents | 27.04 | 24.75 | 6 | 7664 | 173655 | 29393202 |
Micturition disorder | 26.81 | 24.75 | 12 | 7658 | 1889 | 29564968 |
Aggression | 26.53 | 24.75 | 39 | 7631 | 35502 | 29531355 |
Binge eating | 26.52 | 24.75 | 6 | 7664 | 97 | 29566760 |
Dysphagia | 25.86 | 24.75 | 49 | 7621 | 54877 | 29511980 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Hallucination | 509.26 | 19.41 | 245 | 10358 | 72543 | 64415586 |
Dyskinesia | 367.20 | 19.41 | 162 | 10441 | 39226 | 64448903 |
Hallucination, visual | 323.90 | 19.41 | 134 | 10469 | 27700 | 64460429 |
Impulse-control disorder | 261.24 | 19.41 | 59 | 10544 | 1529 | 64486600 |
On and off phenomenon | 219.35 | 19.41 | 56 | 10547 | 2463 | 64485666 |
Fall | 215.57 | 19.41 | 301 | 10302 | 416525 | 64071604 |
Orthostatic hypotension | 177.70 | 19.41 | 105 | 10498 | 46633 | 64441496 |
Hypersexuality | 169.56 | 19.41 | 41 | 10562 | 1438 | 64486691 |
Gambling disorder | 154.61 | 19.41 | 40 | 10563 | 1854 | 64486275 |
Serotonin syndrome | 153.90 | 19.41 | 90 | 10513 | 39192 | 64448937 |
Freezing phenomenon | 152.60 | 19.41 | 38 | 10565 | 1508 | 64486621 |
Delusion | 129.70 | 19.41 | 62 | 10541 | 17952 | 64470177 |
Dopamine dysregulation syndrome | 124.90 | 19.41 | 26 | 10577 | 453 | 64487676 |
Confusional state | 121.83 | 19.41 | 180 | 10423 | 260964 | 64227165 |
Bradykinesia | 109.32 | 19.41 | 41 | 10562 | 6519 | 64481610 |
Resting tremor | 92.21 | 19.41 | 25 | 10578 | 1389 | 64486740 |
Muscle rigidity | 90.14 | 19.41 | 48 | 10555 | 17425 | 64470704 |
Dystonia | 86.69 | 19.41 | 48 | 10555 | 18817 | 64469312 |
Tremor | 86.64 | 19.41 | 114 | 10489 | 148116 | 64340013 |
Sudden onset of sleep | 75.75 | 19.41 | 18 | 10585 | 585 | 64487544 |
Stoma site discharge | 61.66 | 19.41 | 19 | 10584 | 1663 | 64486466 |
Akinesia | 61.51 | 19.41 | 22 | 10581 | 3057 | 64485072 |
Compulsive shopping | 61.43 | 19.41 | 16 | 10587 | 761 | 64487368 |
Nocturia | 61.35 | 19.41 | 32 | 10571 | 11133 | 64476996 |
Jealous delusion | 57.32 | 19.41 | 12 | 10591 | 215 | 64487914 |
Abnormal behaviour | 54.97 | 19.41 | 45 | 10558 | 33577 | 64454552 |
Rapid eye movement sleep behaviour disorder | 52.46 | 19.41 | 12 | 10591 | 329 | 64487800 |
Dementia | 52.27 | 19.41 | 36 | 10567 | 20730 | 64467399 |
Cogwheel rigidity | 51.82 | 19.41 | 19 | 10584 | 2834 | 64485295 |
Supine hypertension | 51.78 | 19.41 | 12 | 10591 | 349 | 64487780 |
Agitation | 51.62 | 19.41 | 68 | 10535 | 88299 | 64399830 |
Drug interaction | 51.38 | 19.41 | 153 | 10450 | 361930 | 64126199 |
Balance disorder | 51.23 | 19.41 | 66 | 10537 | 83860 | 64404269 |
Stereotypy | 50.78 | 19.41 | 14 | 10589 | 828 | 64487301 |
Marasmus | 50.36 | 19.41 | 14 | 10589 | 854 | 64487275 |
Autonomic nervous system imbalance | 48.35 | 19.41 | 20 | 10583 | 4112 | 64484017 |
Hyperthermia | 46.47 | 19.41 | 30 | 10573 | 15520 | 64472609 |
Hyperkinesia | 46.40 | 19.41 | 17 | 10586 | 2529 | 64485600 |
Psychotic disorder | 45.75 | 19.41 | 41 | 10562 | 34537 | 64453592 |
Disturbance in attention | 45.29 | 19.41 | 44 | 10559 | 41030 | 64447099 |
Pleurothotonus | 44.30 | 19.41 | 16 | 10587 | 2286 | 64485843 |
Somnolence | 44.22 | 19.41 | 101 | 10502 | 203544 | 64284585 |
Mesenteric artery thrombosis | 42.01 | 19.41 | 11 | 10592 | 534 | 64487595 |
Gait disturbance | 41.45 | 19.41 | 89 | 10514 | 172066 | 64316063 |
Stoma site erythema | 41.24 | 19.41 | 13 | 10590 | 1226 | 64486903 |
Choking | 40.84 | 19.41 | 24 | 10579 | 10514 | 64477615 |
Anxiety | 40.17 | 19.41 | 97 | 10506 | 202552 | 64285577 |
Sleep talking | 39.48 | 19.41 | 12 | 10591 | 1003 | 64487126 |
Obsessive-compulsive personality disorder | 39.43 | 19.41 | 8 | 10595 | 122 | 64488007 |
Fracture | 39.11 | 19.41 | 29 | 10574 | 18726 | 64469403 |
Paraphilia | 38.41 | 19.41 | 7 | 10596 | 58 | 64488071 |
Compulsive hoarding | 37.60 | 19.41 | 7 | 10596 | 66 | 64488063 |
Oesophageal achalasia | 34.91 | 19.41 | 10 | 10593 | 680 | 64487449 |
Micturition urgency | 33.48 | 19.41 | 21 | 10582 | 10338 | 64477791 |
Dysphagia | 32.61 | 19.41 | 61 | 10542 | 106751 | 64381378 |
Impulsive behaviour | 31.53 | 19.41 | 13 | 10590 | 2650 | 64485479 |
Abnormal dreams | 30.99 | 19.41 | 20 | 10583 | 10336 | 64477793 |
Aggression | 30.80 | 19.41 | 38 | 10565 | 46194 | 64441935 |
Therapeutic product effect variable | 30.05 | 19.41 | 11 | 10592 | 1633 | 64486496 |
Altered state of consciousness | 29.96 | 19.41 | 34 | 10569 | 37868 | 64450261 |
Neuroleptic malignant syndrome | 29.87 | 19.41 | 28 | 10575 | 24968 | 64463161 |
Device dislocation | 29.78 | 19.41 | 26 | 10577 | 21152 | 64466977 |
Speech disorder | 29.39 | 19.41 | 38 | 10565 | 48403 | 64439726 |
Psychomotor hyperactivity | 29.36 | 19.41 | 22 | 10581 | 14429 | 64473700 |
Middle insomnia | 29.32 | 19.41 | 21 | 10582 | 12856 | 64475273 |
Blood lactic acid | 29.32 | 19.41 | 8 | 10595 | 455 | 64487674 |
Hyperpyrexia | 29.18 | 19.41 | 15 | 10588 | 5062 | 64483067 |
Parkinsonian gait | 28.64 | 19.41 | 9 | 10594 | 840 | 64487289 |
Presyncope | 28.63 | 19.41 | 32 | 10571 | 35057 | 64453072 |
Syncope | 28.62 | 19.41 | 73 | 10530 | 157562 | 64330567 |
Cognitive disorder | 28.52 | 19.41 | 40 | 10563 | 55047 | 64433082 |
Anticholinergic syndrome | 28.15 | 19.41 | 12 | 10591 | 2657 | 64485472 |
Coronary artery dissection | 28.03 | 19.41 | 9 | 10594 | 901 | 64487228 |
Nightmare | 27.98 | 19.41 | 25 | 10578 | 20968 | 64467161 |
Toxicity to various agents | 27.03 | 19.41 | 13 | 10590 | 363500 | 64124629 |
Obsessive-compulsive disorder | 27.01 | 19.41 | 14 | 10589 | 4804 | 64483325 |
Disorientation | 26.65 | 19.41 | 39 | 10564 | 55789 | 64432340 |
Pneumonia aspiration | 26.28 | 19.41 | 40 | 10563 | 59231 | 64428898 |
Micturition disorder | 26.25 | 19.41 | 12 | 10591 | 3136 | 64484993 |
Gastrointestinal motility disorder | 26.06 | 19.41 | 14 | 10589 | 5165 | 64482964 |
Sleep attacks | 25.77 | 19.41 | 6 | 10597 | 178 | 64487951 |
Drooling | 25.71 | 19.41 | 14 | 10589 | 5305 | 64482824 |
Sleep disorder | 24.66 | 19.41 | 39 | 10564 | 59670 | 64428459 |
Thunderclap headache | 24.55 | 19.41 | 6 | 10597 | 220 | 64487909 |
Hip fracture | 24.34 | 19.41 | 26 | 10577 | 27073 | 64461056 |
Intermittent claudication | 23.46 | 19.41 | 11 | 10592 | 3043 | 64485086 |
Serum serotonin increased | 23.31 | 19.41 | 6 | 10597 | 272 | 64487857 |
Prescribed underdose | 23.11 | 19.41 | 21 | 10582 | 17994 | 64470135 |
Insomnia | 22.85 | 19.41 | 78 | 10525 | 197758 | 64290371 |
Diarrhoea | 22.43 | 19.41 | 54 | 10549 | 722650 | 63765479 |
Device occlusion | 22.19 | 19.41 | 16 | 10587 | 9897 | 64478232 |
Compulsions | 22.01 | 19.41 | 6 | 10597 | 340 | 64487789 |
Delirium | 21.71 | 19.41 | 40 | 10563 | 69154 | 64418975 |
Off label use | 21.48 | 19.41 | 45 | 10558 | 632761 | 63855368 |
Reduced facial expression | 20.64 | 19.41 | 9 | 10594 | 2104 | 64486025 |
Psychotic symptom | 20.54 | 19.41 | 9 | 10594 | 2129 | 64486000 |
Poor quality sleep | 20.32 | 19.41 | 20 | 10583 | 18931 | 64469198 |
Death | 20.17 | 19.41 | 142 | 10461 | 482563 | 64005566 |
Underdose | 20.12 | 19.41 | 23 | 10580 | 25806 | 64462323 |
Hyperhidrosis | 19.78 | 19.41 | 55 | 10548 | 124865 | 64363264 |
Anosmia | 19.63 | 19.41 | 11 | 10592 | 4406 | 64483723 |
Parkinsonism hyperpyrexia syndrome | 19.46 | 19.41 | 5 | 10598 | 225 | 64487904 |
None
Source | Code | Description |
---|---|---|
ATC | N04BD02 | NERVOUS SYSTEM ANTI-PARKINSON DRUGS DOPAMINERGIC AGENTS Monoamine oxidase B inhibitors |
FDA MoA | N0000000184 | Monoamine Oxidase Inhibitors |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D008996 | Monoamine Oxidase Inhibitors |
MeSH PA | D018696 | Neuroprotective Agents |
MeSH PA | D020011 | Protective Agents |
FDA EPC | N0000175744 | Monoamine Oxidase Inhibitor |
CHEBI has role | CHEBI:38623 | monoamine oxidase inhibitors |
CHEBI has role | CHEBI:63726 | neuroprotective agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Parkinson's disease | indication | 49049000 | DOID:14330 |
Dyskinesia | contraindication | 9748009 | |
Bipolar disorder | contraindication | 13746004 | DOID:3312 |
Orthostatic hypotension | contraindication | 28651003 | |
Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Disease of liver | contraindication | 235856003 | DOID:409 |
Pheochromocytoma | contraindication | 302835009 | |
Malignant melanoma | contraindication | 372244006 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 7.54 | Basic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
EQ 0.5MG BASE | AZILECT | TEVA | N021641 | May 16, 2006 | RX | TABLET | ORAL | 7815942 | Aug. 27, 2027 | TREATMENT OF PARKINSONS DISEASE |
EQ 1MG BASE | AZILECT | TEVA | N021641 | May 16, 2006 | RX | TABLET | ORAL | 7815942 | Aug. 27, 2027 | TREATMENT OF PARKINSONS DISEASE |
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] B | Enzyme | INHIBITOR | Ki | 6.15 | CHEMBL | CHEMBL | |||
Acetylcholinesterase | Enzyme | IC50 | 7.72 | CHEMBL | |||||
5-hydroxytryptamine receptor 6 | GPCR | Ki | 8.85 | CHEMBL | |||||
Amine oxidase [flavin-containing] A | Enzyme | Ki | 5.01 | CHEMBL | |||||
Cholinesterase | Enzyme | IC50 | 5.32 | CHEMBL | |||||
Amine oxidase [flavin-containing] B | Enzyme | IC50 | 8.36 | CHEMBL | |||||
Amine oxidase [flavin-containing] A | Enzyme | IC50 | 6.39 | CHEMBL |
ID | Source |
---|---|
4025261 | VUID |
N0000179514 | NUI |
D02562 | KEGG_DRUG |
136236-50-5 | SECONDARY_CAS_RN |
161735-79-1 | SECONDARY_CAS_RN |
4025261 | VANDF |
4025262 | VANDF |
C0525678 | UMLSCUI |
CHEBI:63620 | CHEBI |
RAU | PDB_CHEM_ID |
CHEMBL887 | ChEMBL_ID |
DB01367 | DRUGBANK_ID |
CHEMBL1201142 | ChEMBL_ID |
CHEMBL1235738 | ChEMBL_ID |
3052776 | PUBCHEM_CID |
7151 | INN_ID |
C031967 | MESH_SUPPLEMENTAL_RECORD_UI |
6641 | IUPHAR_LIGAND_ID |
003N66TS6T | UNII |
134748 | RXNORM |
162358 | MMSL |
20417 | MMSL |
70623 | MMSL |
d05612 | MMSL |
010775 | NDDF |
010776 | NDDF |
418734001 | SNOMEDCT_US |
419010007 | SNOMEDCT_US |
734664007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3060 | TABLET | 0.50 mg | ORAL | NDA authorized generic | 29 sections |
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3060 | TABLET | 0.50 mg | ORAL | NDA authorized generic | 29 sections |
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3061 | TABLET | 1 mg | ORAL | NDA authorized generic | 29 sections |
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0093-3061 | TABLET | 1 mg | ORAL | NDA authorized generic | 29 sections |
Rasagiline Mesylate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-1270 | TABLET | 0.50 mg | ORAL | ANDA | 30 sections |
Rasagiline Mesylate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-1270 | TABLET | 0.50 mg | ORAL | ANDA | 30 sections |
Rasagiline Mesylate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-1271 | TABLET | 1 mg | ORAL | ANDA | 30 sections |
Rasagiline Mesylate | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-1271 | TABLET | 1 mg | ORAL | ANDA | 30 sections |
Rasagiline | Human Prescription Drug Label | 1 | 16714-770 | TABLET | 0.50 mg | ORAL | ANDA | 29 sections |
Rasagiline | Human Prescription Drug Label | 1 | 16714-771 | TABLET | 1 mg | ORAL | ANDA | 29 sections |
Rasagiline Mesylate | Human Prescription Drug Label | 1 | 23155-746 | TABLET | 0.50 mg | ORAL | ANDA | 29 sections |
Rasagiline Mesylate | Human Prescription Drug Label | 1 | 23155-747 | TABLET | 1 mg | ORAL | ANDA | 29 sections |
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-779 | TABLET | 0.50 mg | ORAL | NDA authorized generic | 29 sections |
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-780 | TABLET | 1 mg | ORAL | NDA authorized generic | 29 sections |
RASAGILINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42571-220 | TABLET | 0.50 mg | ORAL | ANDA | 29 sections |
RASAGILINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42571-221 | TABLET | 1 mg | ORAL | ANDA | 29 sections |
Azilect | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43353-015 | TABLET | 1 mg | ORAL | NDA | 30 sections |
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 47781-683 | TABLET | 0.50 mg | ORAL | ANDA | 27 sections |
Rasagiline | HUMAN PRESCRIPTION DRUG LABEL | 1 | 47781-690 | TABLET | 1 mg | ORAL | ANDA | 27 sections |
Azilect | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-6206 | TABLET | 1 mg | ORAL | NDA | 30 sections |
Rasagiline | Human Prescription Drug Label | 1 | 67877-259 | TABLET | 0.50 mg | ORAL | ANDA | 29 sections |
Rasagiline | Human Prescription Drug Label | 1 | 67877-260 | TABLET | 1 mg | ORAL | ANDA | 29 sections |
Azilect | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68546-142 | TABLET | 0.50 mg | ORAL | NDA | 30 sections |
Azilect | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68546-142 | TABLET | 0.50 mg | ORAL | NDA | 30 sections |
Azilect | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68546-229 | TABLET | 1 mg | ORAL | NDA | 30 sections |
Azilect | HUMAN PRESCRIPTION DRUG LABEL | 1 | 68546-229 | TABLET | 1 mg | ORAL | NDA | 30 sections |