betamethasone butyrate propionate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 352 5534-02-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • antebate
  • betamethasone butyrate propionate
a topical corticosteroid
  • Molecular weight: 518.62
  • Formula: C29H39FO7
  • CLOGP: 4.45
  • LIPINSKI: 1
  • HAC: 7
  • HDO: 1
  • TPSA: 106.97
  • ALOGS: -5.11
  • ROTB: 9

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 0.06 mg/mL Bocci G, Oprea TI, Benet LZ

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:35705 immunosuppressive agents
CHEBI has role CHEBI:65023 anti-asthmatic agents
MeSH PA D018927 Anti-Asthmatic Agents
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
MeSH PA D019141 Respiratory System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.48 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D02032 KEGG_DRUG
1514 RXNORM
CHEBI:135815 CHEBI
CHEBI:3077 CHEBI
CHEMBL1697785 ChEMBL_ID
C000612965 MESH_SUPPLEMENTAL_RECORD_UI
C587113 MESH_SUPPLEMENTAL_RECORD_UI
DB00443 DRUGBANK_ID
10006 MMSL
4270 MMSL
d00628 MMSL
116571008 SNOMEDCT_US
29896003 SNOMEDCT_US
C2698381 UMLSCUI
C0005308 UMLSCUI
4018644 VANDF
71470 PUBCHEM_CID
1045 INN_ID
9782 PUBCHEM_CID
D001623 MESH_DESCRIPTOR_UI
50FH5AG9RW UNII
002168 NDDF

Pharmaceutical products:

None