DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
pyrovalerone 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
3511
3563-49-3
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
pyrovalerone hydrochloride
pyrovalerone
pyrovalerone HCl
Molecular weight: 245.37
Formula: C16H23NO
CLOGP: 4.10
LIPINSKI: 0
HAC: 2
HDO: 0
TPSA: 20.31
ALOGS: -3.08
ROTB: 5
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
MeSH PA
D002491
Central Nervous System Agents
MeSH PA
D000697
Central Nervous System Stimulants
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
8.13
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Sodium-dependent serotonin transporter
Transporter
P31645
SC6A4_HUMAN
Ki
5.42
CHEMBL
Sodium-dependent noradrenaline transporter
Transporter
P23975
SC6A2_HUMAN
Ki
6.71
CHEMBL
Sodium-dependent dopamine transporter
Transporter
Q01959
SC6A3_HUMAN
Ki
8.10
CHEMBL
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External reference:
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ID
Source
1147-62-2
SECONDARY_CAS_RN
14373
PUBCHEM_CID
1737
INN_ID
96248002
SNOMEDCT_US
C005719
MESH_SUPPLEMENTAL_RECORD_UI
C0072777
UMLSCUI
CHEBI:134998
CHEBI
CHEMBL201960
ChEMBL_ID
CHEMBL2104793
ChEMBL_ID
D05663
KEGG_DRUG
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Pharmaceutical products:
None
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Structure 🔎
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pyrovalerone