pyrovalerone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
	3511	3563-49-3

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

pyrovalerone hydrochloride
pyrovalerone
pyrovalerone HCl

Molecular weight: 245.37
Formula: C16H23NO
CLOGP: 4.10
LIPINSKI: 0
HAC: 2
HDO: 0
TPSA: 20.31
ALOGS: -3.08
ROTB: 5

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event term	Likelihood ratio	Likelihood ratio threshold	Patients taking drug having adverse event	Patients taking drug not having adverse event	Patients not taking drug having adverse event	Patients not taking drug not having adverse event
Victim of sexual abuse	52.01	46.87	5	6	468	70927965

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D002491	Central Nervous System Agents
MeSH PA	D000697	Central Nervous System Stimulants

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation level	Dissociation constant	Type (acidic/basic)
pKa1	8.13	Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Sodium-dependent serotonin transporter	Transporter	P31645	SC6A4_HUMAN		Ki	5.42		CHEMBL
Sodium-dependent noradrenaline transporter	Transporter	P23975	SC6A2_HUMAN		Ki	6.71		CHEMBL
Sodium-dependent dopamine transporter	Transporter	Q01959	SC6A3_HUMAN		Ki	8.10		CHEMBL

External reference:

ID	Source
D05663	KEGG_DRUG
1147-62-2	SECONDARY_CAS_RN
C0072777	UMLSCUI
CHEBI:134998	CHEBI
CHEMBL201960	ChEMBL_ID
CHEMBL2104793	ChEMBL_ID
C005719	MESH_SUPPLEMENTAL_RECORD_UI
14373	PUBCHEM_CID
1737	INN_ID
VOU69C02JP	UNII
96248002	SNOMEDCT_US

Pharmaceutical products:

None