benzylthiouracil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
uracil derivatives used as thyroid antagonists 339 6336-50-1

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • bentiuracil
  • basdene
  • 6-Benzyl-2-thiouracil
  • benzylthiouracil
  • Molecular weight: 218.27
  • Formula: C11H10N2OS
  • CLOGP: 1.48
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 41.13
  • ALOGS: -3.64
  • ROTB: 2

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC H03BA03 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
THYROID THERAPY
ANTITHYROID PREPARATIONS
Thiouracils

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.72 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
19084 RXNORM
C0053332 UMLSCUI
CHEBI:134902 CHEBI
CHEMBL1491306 ChEMBL_ID
DB13804 DRUGBANK_ID
C019269 MESH_SUPPLEMENTAL_RECORD_UI
PZ35LUM333 UNII
685814 PUBCHEM_CID
713402004 SNOMEDCT_US
005312 NDDF

Pharmaceutical products:

None